- Jun 2017
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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The other anaerobes tested – A. vaginae, M. mulieris, P. bivia, Veillonella, Peptostreptococcus and Peptoniphilus – demonstrated significantly lower biofilm formation relative to G. vaginalis (Student's t-test, P<0.0001).
virulence - biofilm production by Gardnerella vaginalis & Mobiluncus mulieris
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Analysis of adherence, biofilm formation and cytotoxicity suggests a greater virulence potential of Gardnerella vaginalis relative to other bacterial-vaginosis-associated anaerobes
adherence, biofilm, cytotoxicity
virulence factors for G. vaginalis
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wwwnc.cdc.gov wwwnc.cdc.gov
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Many mycoplasmal pathogens exhibit filamentous or flask-shaped appearances and display prominent and specialized polar tip organelles that mediate attachment to host target cells (43,44). These tip structures are complex, composed of a network of interactive proteins, designated adhesins, and adherence-accessory proteins (Figure 1, [14,43]).
Mycoplasma virulence - specialized polar tip organelles
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www.ejmm.edu.eg www.ejmm.edu.eguntitled1
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Once they attach to a host cell in the body, their unique plasma and protein coating can then mimic the cell wall of the host cell and the immune system can not differentiate the mycoplasma from the body’s own host cell (1).
virulence, Mycoplasma
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academic.oup.com academic.oup.com
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G. vaginalis was isolated from the vaginal sample by streaking the specimen on a selective human blood Tween (HBT) bilayer agar medium (Becton-Dickinson).
Culturing techniques
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- May 2017
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www.ashasexualhealth.org www.ashasexualhealth.org
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Trich can cause genital inflammation that makes it easier to become infected with the HIV virus or to pass the HIV virus on to a sex partner.
complications of parasitic vaginitis (trichomoniasis)
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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epithelial cells, biofilm production, surface hydrophobicity, phospholipase C and protease activity
Virulence factors of G. vaginalis
Tags
Annotators
URL
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Gardnerella vaginalis, Mycoplasma hominis and various anaerobic bacteria including Mobiluncus sp., and Prevotella sp.
Other probabe causative organism
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These are primarily anaerobic bacteria and an organism called Gardnerella vaginalis,
A possible caustative organism. No one really knows for sure.
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www.cdc.gov www.cdc.gov
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A health care provider will examine your vagina for signs of vaginal discharge. Your provider can also perform laboratory tests on a sample of vaginal fluid to determine if BV is present.
test vaginal fluid to determine for presence of bacterial vaginosis
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Bacterial vaginosis is the most common vaginal infection in women ages 15-44.
Common age
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emedicine.medscape.com emedicine.medscape.com
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Bacterial Vaginosis Workup
Determining if there is a case
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www.medicalnewstoday.com www.medicalnewstoday.com
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Clindamyci
Alternative treatments if metronidazole does not work. If it comes back despite using clindamycin, use tinidazole.
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Metronidazole is the most common antibiotic for BV.
Most common form of treatment for bacterial vaginitis.
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www.webmd.com www.webmd.com
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fishy smell, bacterial vaginosis is a better guess
Bacterial-fishy smell while yeast overgrowth looks like cottage cheese
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www.mayoclinic.org www.mayoclinic.org
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The most common types of vaginitis are:
Bacteria, yeast, and parasite
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