SeqAn implements various applications that can be used for different tasks for example to map reads, apply read error correction, conduct protein searches, run variant detection and many more. However, analysts are not interested in a single execution of one tool but design and execute entire pipelines using different tools for different tasks contained in the pipeline. Often they also require some downstream analysis steps, e.g. computing some statistics, generating reports and so on. Hence it was desirable to add SeqAn applications to the KNIME workflow engine, which offers many additional analysis and data mining features.