1 Matching Annotations
  1. May 2019
    1. However, unlike insulin signaling, UNC-43 phosphorylates and activates DAF-16, thus promoting its nuclear localization. The phosphorylation of DAF-16 at S286 by UNC-43 is removed by TAX-6•CNB-1, leading to DAF-16 inactivation.

      Kinase: UNC-43 (O62305) <br /> Substrate: DAF-16 (O16850) <br /> Site: Ser-286