1 Matching Annotations
- Nov 2022
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cccrg.cochrane.org cccrg.cochrane.org
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PDF summary by Cochrane for planning a meta-analysis at the protocol stage. Gives guidance on how to anticipate & deal with various types of heterogeneity (clinical, methodological , & statistical). Link to paper
Covers - ways to assess heterogeneity - courses of action if substantial heterogeneity is found - methods to examine the influence of effect modifiers (either to explore heterogeneity or because there's good reason to suggest specific features of participants/interventions/study types will influence effects of the intervention. - methods include subgroup analyses & meta-regression
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