- May 2021
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pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
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Conclusion: The combination of ultra-low-dose naltrexone and morphine in extremity trauma does not affect the opioid requirements; it, however, lowers the risk of nausea.
From the full text, they used 5 micrograms of naltrexone. Naltrexone dose is very finicky. There's low dose (LDN), very low dose (VLDN), and ultra-low dose (ULDN). This is a ULDN. I believe the type of effects I'm looking for occur at VLDN and LDN doses. If I recall correctly, I think 2 mg is optimal for analgesia, but I don't remember whether this was with or without morphine. 0.125 mg and 0.25 mg are effective in opioid withdrawal when combined with methadone. Thus, it's not too surprising that 5 mcg had little effect. At those doses, the effects it does have are like mediated by different mechanisms.
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- Sep 2016
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rxshoppingmart.com rxshoppingmart.com
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Morphine 100mg is a pain killer medicinal drug that is used inside the remedy if slight to intense pain.. every pill incorporates a hundred mg of morphine sulphate.
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