3 Matching Annotations
  1. Jul 2025
    1. level of improvement provided by MetAMOS over other assembly tools is highly dependent on the specific characteristics of the dataset being assembled
      • library size re-estimation within MetAMOS (was incorrect in tongue dorsum dataset so helped a lot)
      • Number of regions of genomic variation (helps real datasets that have a high number of these since scaffold building pipeline is good)
    2. aggressive assembly approaches sometimes result in more contiguous assemblies, but often introduce errors of the most severe kind (chimeras)

      There are trade-offs. - Could we ask the user if the tool should err on more contiguous vs chimeras with a set % - or summarize results from both and ask the user to choose..?