6 Matching Annotations
- Feb 2019
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www.pnas.org www.pnas.org
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Neu5Ac/Neu5Gc ratio may be relevant becauseof likely competition of Neu5Ac with Neu5Gc for incorporationinto cells (34)
Mice could have been fed both to see this competition.
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it is detected in the liver, and in humans, it is detected moreprominently in the colon, prostate, and ovary.
More extensive research on the mechanisms involved in Gc absorption would help draw parallels between the mice and humans. At this point it doesn't seem as though Gc has precisely the same effect on humans as it does on immunized mice.
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45–530 13–29
Because of the high presence of Gc but low percentage, caviar would make a good correlation study for the relationship between carcinomas and Gc% rather than just presence.
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epitopes
An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system
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IL-6, which is frequentlyelevated in chronic liver disease and malignancy
How does Gc effect the human liver?
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