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    Opposing roles for AMPK in regulating distinct mitophagy pathways
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    sciencedirect.com/science/article/pii/S1097276524008657
  3. Nov 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High fat diet induced hepatic insulin resistance per se attenuates murine de novo lipogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11550620/
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    Insulin Mediates Lipopolysaccharide-Induced Inflammatory Responses and Oxidative Stress in BV2 Microglia
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    Bidirectional signals generated by Siglec-7 and its crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance
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  7. Oct 2024
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    Midkine as a driver of age-related changes and increase in mammary tumorigenesis
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    sciencedirect.com/science/article/pii/S1535610824003507
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    Voluntary exercise suppresses inflammation and improves insulin resistance in the arcuate nucleus and ventral tegmental area in mice on a high-fat diet
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    sciencedirect.com/science/article/pii/S0031938424002518
  10. Sep 2024
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    Zdhhc1- and Zdhhc2-mediated Gpm6a palmitoylation is essential for maintenance of mammary stem cell activity
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    sciencedirect.com/science/article/pii/S2211124724011136
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    PI3K isoform-selective inhibition in neuron-specific PTEN-deficient mice rescues molecular defects and reduces epilepsy-associated phenotypes
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    sciencedirect.com/science/article/pii/S0969996120303016
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    Amino alkynylisoquinoline and alkynylnaphthyridine compounds potently inhibit acute myeloid leukemia proliferation in mice
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    Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice
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    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PlexinB1 Inactivation Reprograms Immune Cells in the Tumor Microenvironment, Inhibiting Breast Cancer Growth and Metastatic Dissemination
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    IGF1 promotes human myotube differentiation toward a mature metabolic and contractile phenotype
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    Anti-HDGF antibody targets EGFR tyrosine kinase inhibitor-tolerant cells in NSCLC patient-derived xenografts
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  19. Aug 2024
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    MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation
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    sciencedirect.com/science/article/pii/S2211124724010337
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    PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8+ T cell ferroptosis
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    sciencedirect.com/science/article/pii/S1074761324003765
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    Integrative plasma and fecal metabolomics identify functional metabolites in adenoma-colorectal cancer progression and as early diagnostic biomarkers
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  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers
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    Epigenetic repression of de novo cysteine synthetases induces intra-cellular accumulation of cysteine in hepatocarcinoma by up-regulating the cystine uptake transporter xCT
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    ncbi.nlm.nih.gov/pmc/articles/PMC11304919/
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    The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes
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    Hepatic BMAL1 and HIF1α regulate a time-dependent hypoxic response and prevent hepatopulmonary-like syndrome
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    sciencedirect.com/science/article/pii/S1550413124002742
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    A TNF receptor 2 agonist ameliorates neuropathology and improves cognition in an Alzheimer’s disease mouse model
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  28. www.mdpi.com www.mdpi.com
    Ellagic Acid Prevents α-Synuclein Aggregation and Protects SH-SY5Y Cells from Aggregated α-Synuclein-Induced Toxicity via Suppression of Apoptosis and Activation of Autophagy
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  29. Jul 2024
  30. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA metabolism maintains histone acetylation for syncytialization of human placental trophoblast stem cells
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    sciencedirect.com/science/article/pii/S1934590924002534
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KIT in oocytes: a key factor for oocyte survival and reproductive lifespan
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    Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration
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    High-fat diet enhances starvation-induced hyperactivity via sensitizing hunger-sensing neurons in Drosophila
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      DOI: 10.7554/eLife.53103

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    Decoding sunitinib resistance in ccRCC: Metabolic-reprogramming-induced ABAT and GABAergic system shifts
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  35. www.science.org www.science.org
    Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers
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  36. dx.doi.org dx.doi.org
    Cenicriviroc Suppresses and Reverses Steatohepatitis by Regulating Macrophage Infiltration and M2 Polarization in Mice
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      DOI: 10.1210/endocr/bqae069

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  37. www.science.org www.science.org
    In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss
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    Multi-step regulation of microRNA expression and secretion into small extracellular vesicles by insulin
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    sciencedirect.com/science/article/pii/S2211124724008209
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Energy‑stress‑mediated activation of AMPK sensitizes MPS1 kinase inhibition in triple‑negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11223027/
  40. Jun 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetyl-NPKY of Integrin-beta 1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity.
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    ncbi.nlm.nih.gov/pmc/articles/PMC11187247/
  42. journals.plos.org journals.plos.org
    Myosin II mediates Shh signals to shape dental epithelia via control of cell adhesion and movement
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      DOI: 10.1371/journal.pgen.1011326

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    journals.plos.org/plosgenetics/article
  43. www.science.org www.science.org
    In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss
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  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptomic characterization of lung pericytes in systemic sclerosis-associated pulmonary fibrosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11167435/
  45. May 2024
  46. 52.53.155.43 52.53.155.43
    PIIS2589004224013336-html.html
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    Discovery of a novel potent EGFR inhibitor against EGFR activating mutations and on-target resistance in NSCLC
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      DOI: 10.1158/1078-0432.CCR-23-2951

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    The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability
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    Astragaloside IV promotes cerebral angiogenesis and neurological recovery after focal ischemic stroke in mice via activating PI3K/Akt/mTOR signaling pathway
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    TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory
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    Resistance wheel running improves contractile strength, but not metabolic capacity, in a murine model of volumetric muscle loss injury
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    Allyl isothiocyanate mitigates airway inflammation and constriction in a house dust mite-induced allergic asthma model via upregulation of tight junction proteins and the TRPA1 modulation
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    Tyrosine Kinase Inhibitors Diminish Renal Neoplasms in a Tuberous Sclerosis Model via induction of Apoptosis
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  131. Jun 2023
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    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    UBE2M-mediated neddylation of TRIM21 regulates obesity-induced inflammation and metabolic disorders
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    Endothelial MRs mediate Western diet-induced lipid disorders and skeletal muscle insulin resistance in females
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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fasting produces antidepressant-like effects via activating mammalian target of rapamycin complex 1 signaling pathway in ovariectomized mice
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    Identification and validation of Rab11a in Rat orofacial inflammatory pain model induced by CFA
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    PICT-1 regulates p53 splicing and sensitivity of medullary thyroid carcinoma cells to Everolimus
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    ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis
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    Kinetics of RTK activation determine ERK reactivation and resistance to dual BRAF/MEK inhibition in melanoma
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    Impacts of High Fructose Diet and Chronic Exercise on Nitric Oxide Synthase and Oxidative Stress in Rat Kidney
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    AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells
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    PAC1 deficiency protects obese male mice from immobilization-induced muscle atrophy by suppressing FoxO-atrogene axis
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    PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity
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    Dihydroartemisinin inhibited stem cell-like properties and enhanced oxaliplatin sensitivity of colorectal cancer via AKT/mTOR signaling
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  150. Apr 2023
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    PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion
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    Piezo1 induces endothelial responses to shear stress via soluble adenylyl Cyclase-IP3R2 circuit
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    Live-cell imaging identifies cAMP microdomains regulating β-adrenoceptor-subtype-specific lipolytic responses in human white adipocytes
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    Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness
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    Statins enhances antitumor effect of oxaliplatin in KRAS-mutated colorectal cancer cells and inhibits oxaliplatin-induced neuropathy
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    Rapamycin treatment unmasks a sex-specific pattern of scar expansion of the infarcted rat heart: The relationship between mTOR and KATP channel
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    PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection
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    Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination
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    Chronic cortisol elevation restricts glucose uptake but not insulin responsiveness in zebrafish skeletal muscle
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  174. Jan 2023
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    Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development
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    Glutamine and leucine administration attenuates muscle atrophy in sepsis
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    The TAZ-CAMTA1 Fusion Protein Promotes Tumorigenesis via Connective Tissue Growth Factor and Ras–MAPK Signaling in Epithelioid Hemangioendothelioma
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    Dysregulation of ErbB4 Signaling Pathway in the Dorsal Hippocampus after Neonatal Hypoxia-Ischemia and Late Deficits in PV+ Interneurons, Synaptic Plasticity and Working Memory
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