Differential susceptibility is a technical term used to describe the ways that different people and different groups have different responses to technology even on the same platform. Similar versions of it can be applied to other areas outside of technology, which is but one target. Other areas include differential well-being and mental health.

It could also be applied to drug addiction as some are more susceptible to becoming addicted to nicotine than others. Which parts of this might be nature, nurture, culture, etc.