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- Feb 2018
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- Oct 2017
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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In the case of molecules targeting CD19 on B cells, one cannot exclude a possible co-signal triggered by the interaction between CD28 and B7, known to be expressed on normal and malignant B cells. However, BiTE molecules targeting EpCAM expressed on a variety of solid tumor of epithelial origin that do not express B7 show similar efficacy.
cosignal trigger
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