- May 2018
One group received citalopram (up to 60 mg/day) plus vitamin C (up to 1,000 mg/day). The other group received citalopram plus placebo.
Considering the results of other trials with different depression severities and vitamin C dosage and forms (sustained release) (covered in this article), it is astonishing that the researchers used such a single, modest, non-sustained release dose.
The plasma peak of vitamin C is obtained a few hours after the administration. For the rest of the day, the subject is back to baseline.
This is common knowledge.