3 Matching Annotations
  1. Aug 2020
    1. Luban, J., Sattler, R., Mühlberger, E., Graci, J. D., Cao, L., Weetall, M., Trotta, C., Colacino, J. M., Bavari, S., Strambio-De-Castillia, C., Suder, E. L., Wang, Y., Soloveva, V., Cintron-Lue, K., Naryshkin, N. A., Pykett, M., Welch, E. M., O’Keefe, K., Kong, R., … Peltz, S. (2020). The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines. BioRxiv, 2020.08.05.238394. https://doi.org/10.1101/2020.08.05.238394

  2. May 2018
    1. One group received citalopram (up to 60 mg/day) plus vitamin C (up to 1,000 mg/day). The other group received citalopram plus placebo.

      Considering the results of other trials with different depression severities and vitamin C dosage and forms (sustained release) (covered in this article), it is astonishing that the researchers used such a single, modest, non-sustained release dose.

      The plasma peak of vitamin C is obtained a few hours after the administration. For the rest of the day, the subject is back to baseline.

      This is common knowledge.

  3. Mar 2018
    1. The pharmacokinetics of Alcar are complex,similar to other naturally occurring substances andinclude partial prehepatic metabolism, first liver passeffect and varying bioavailability

      The pharmacokinetics of alcar