10 Matching Annotations
  1. Mar 2020
    1. mechanical integrity and function of collagen

      The demonstration of the mechanical integrity is important to the overall function of the model. If the heart cannot withstand the stresses from normally bodily functions, it will not serve as a good replacement in a human body.

    2. creating a regulatory process for clinical translation

      Since the field is ever-changing and rather new, there is not an existing method to regulate products and approve their effectiveness. Before any sort of product can be approved to be used in patients, a regulatory process must be put into place.

    3. mechanical properties by adapting published fixation protocols

      It is important that all standards are met, especially when creating any sort of medical product. The standards insure that the device will be able to withstand the stresses that accompanying bodily functions.

    4. self-assemble vascular networks

      Angiogenesis is essential to the growth and repair of new tissue, providing cells with replenishing resources. In some situations though, excess vascularization can cause some problems which are addressed in the accompanying article.

    5. proof of concept

      It is important to note the value of understanding the reason for why work is being done and how it will affect future research. While not all research ends with a finished product or breakthrough, smaller research projects are important to lay the foundation for future work.

    6. computational method

      Computational modeling is a helpful tool in determining the effectiveness of medical products and experiments. They help speed up discovery and testing.

  2. Feb 2020
    1. microvascularization

      formation of small blood vessels

    2. Engineering smaller-scale vasculature

      This novel research displays a new method to the progression of tissue engineering by presenting a new method to 3D print smaller-scale vasculature. This method can prove to be useful in future Tissue Engineering applications.

    3. To accomplish this, we developed a substantiallyimproved second generation of the freeformreversible embedding of suspended hydrogels(FRESH v2.0

      This exemplifies the idea that research and learning can sometimes take multiple tries to perfect an idea.

    4. Three-dimensional (3D) bio-printing

      This work builds on a relatively new field, bioprinting. A field that poses a variety of ethical dilemmas to policy makers.

      Read more here: https://jme.bmj.com/content/43/9/618