11 Matching Annotations
  1. Apr 2021
    1. John Company: Second Edition is a dramatic reimagining of the first edition that took over two years of extensive design and production work. 
  2. Mar 2021
  3. Feb 2021
  4. Nov 2020
  5. Sep 2020
    1. I think that we should be willing (taking the risk) to make bold changes, as long as they fit in the direction we see the community going in the long term (with Material-UI empowering it).
  6. Aug 2020
    1. Whereas histamine stimulates parietal cells’ excretion of hydrochloric acid through activation of adenylyl cyclase, somatostatin directly opposes this action; somatostatin receptor activation on parietal cells inhibits adenylyl cyclase. This is a form of negative feedback.

      Understanding the interactions here and the negative feedback process is important.

    2. gastrin, histamine, and acetylcholine operate synergistically to promote hydrochloric acid excretion. When operating in concert, the effects of gastrin, histamine, and acetylcholine are greater-than-additive

      Understanding the great-than-additive effect of these signaling molecules working in concert is important. Some students in the summer 2020 class were unsure what this meant, so it may be helpful to add to this description to clarify this greater-than-additive effect, which can also be described as synergistic. This could be something like, "The simultaneous signaling of all three of these molecules produces a synergistic effect that is stronger than the sum of the effects they each produce separately."

  7. Dec 2018
    1. their business

      "THEIR business" Interesting that this claim to partnership is right up front -- in the first item on the list. It's the starting point for what follows.

  8. May 2017
    1. is being eradicated by experimental filmmakers such as Peter Greenaw

      Hmmmm . . . has anyone else seen a film by Peter Greenaway? I was curious what this would look like, so I went through his imdb, and I haven't seen (and had barely heard of) any of his projects, which suggests to me that Manovich is perhaps an unreliable source if he believes Greenaway is successfully eradicating narrative.

  9. Feb 2016