16 Matching Annotations
  1. Mar 2021
    1. Antoine R , Valadão Ana Luiza C , Marine T  et al.   PREPRINT: SARS-CoV-2 replication triggers an MDA-5-dependent interferon production which is unable to efficiently control replication. bioRxiv  2020:2020.10.28.358945. doi:10.1101/2020.10.28.358945.

      Rebendenne A, Valadão ALC, Tauziet M, Maarifi G, Bonaventure B, McKellar J, Planès R, Nisole S, Arnaud-Arnould M, Moncorgé O, Goujon C. SARS-CoV-2 triggers an MDA-5-dependent interferon response which is unable to control replication in lung epithelial cells. J Virol. 2021 Jan 29:JVI.02415-20 https://doi.org/10.1128/JVI.02415-20

    2. Bayati A , Kumar R , Francis V  et al.   PREPRINT: SARS-CoV-2 uses clathrin-mediated endocytosis to gain access into cells. bioRxiv  2020:2020.07.13.201509. doi:10.1101/2020.07.13.201509.

      Bayati A, Kumar R, Francis V, McPherson PS. SARS-CoV-2 infects cells following viral entry via clathrin-mediated endocytosis. J Biol Chem. 2021 Jan 18;296:100306 https://doi.org/10.1016/j.jbc.2021.100306

    3. Zhou Q , Wei X-S , Xiang X  et al.   PREPRINT: Interferon-a2b treatment for COVID-19. medRxiv  2020:2020.04.06.20042580. doi:10.1101/2020.04.06.20042580.

      Zhou, Q., Chen, V., Shannon, C. P., Wei, X.-S., Xiang, X., Wang, X., Wang, Z.-H., Tebbutt, S. J., Kollmann, T. R., & Fish, E. N. (2020). Interferon-α2b Treatment for COVID-19. Front Immunol, 11(1061) https://doi.org/10.3389/fimmu.2020.01061

    4. Baker SA , Kowk S , Berry GJ  et al.   PREPRINT: Angiotensin-converting enzyme 2 (ACE2) expression increases with age in patients requiring mechanical ventilation. medRxiv  2020:2020.07.05.20140467. doi:10.1101/2020.07.05.20140467.

      Baker SA, Kwok S, Berry GJ, Montine TJ. Angiotensin-converting enzyme 2 (ACE2) expression increases with age in patients requiring mechanical ventilation. PLoS One. 2021 Feb 16;16(2):e0247060 https://doi.org/10.1371/journal.pone.0247060

    5. Wang K , Chen W , Zhou Y-S  et al.   PREPRINT: SARS-CoV-2 invades host cells via a novel route: CD147-spike protein. bioRxiv  2020:2020.03.14.988345. doi:10.1101/2020.03.14.988345.

      Wang, K., Chen, W., Zhang, Z. et al. CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells. Sig Transduct Target Ther 5, 283 (2020). https://doi.org/10.1038/s41392-020-00426-x

    6. Zhang L , Jackson CB , Mou H  et al.   PREPRINT: The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity. bioRxiv  2020:2020.06.12.148726. doi:10.1101/2020.06.12.148726.

      Zhang, L., Jackson, C.B., Mou, H. et al. SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity. Nat Commun 11, 6013 (2020). https://doi.org/10.1038/s41467-020-19808-4

    7. Lee IT , Nakayama T , Wu C-T  et al.   PREPRINT: Robust ACE2 protein expression localizes to the motile cilia of the respiratory tract epithelia and is not increased by ACE inhibitors or angiotensin receptor blockers. medRxiv  2020:2020.05.08.20092866. doi:10.1101/2020.05.08.20092866.

      Lee, I.T., Nakayama, T., Wu, CT. et al. ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs. Nat Commun 11, 5453 (2020). https://doi.org/10.1038/s41467-020-19145-6

    1. Cerda P , Ribas J , Iriarte A , et al. ; PREPRINT: D-dimer dynamics in hospitalized COVID-19 patients: potential utility for diagnosis of pulmonary embolism. medRxiv  2020:2020.09.21.20193953. doi: 10.1101/2020.09.21.20193953.

      Cerdà P, Ribas J, Iriarte A, Mora-Luján JM, Torres R, Del Río B, Jofre HI, Ruiz Y, Huguet M, Fuset MP, Martínez-Yélamos S, Santos S, Llecha N, Corbella X, Riera-Mestre A. Blood test dynamics in hospitalized COVID-19 patients: Potential utility of D-dimer for pulmonary embolism diagnosis. PLoS One. 2020 Dec 28;15(12):e0243533. https://doi.org/10.1371/journal.pone.0243533

    2. Meizlish ML , Pine AB , Bishai JD  et al.   PREPRINT: a neutrophil activation signature predicts critical illness and mortality in COVID-19. medRxiv  2020. doi:10.1101/2020.09.01.20183897.

      Meizlish ML, Pine AB, Bishai JD, Goshua G, Nadelmann ER, Simonov M, Chang CH, Zhang H, Shallow M, Bahel P, Owusu K, Yamamoto Y, Arora T, Atri DS, Patel A, Gbyli R, Kwan J, Won CH, Dela Cruz C, Price C, Koff J, King BA, Rinder HM, Wilson FP, Hwa J, Halene S, Damsky W, van Dijk D, Lee AI, Chun HJ. A neutrophil activation signature predicts critical illness and mortality in COVID-19. Blood Adv. 2021 Mar 9;5(5):1164-1177. https://doi.org/10.1182/bloodadvances.2020003568

    3. Aschenbrenner AC , Mouktaroudi M , Kraemer B  et al.   PREPRINT: disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients. medRxiv  2020. doi:10.1101/2020.07.07.20148395.

      Aschenbrenner AC, Mouktaroudi M, Krämer B, Oestreich M, Antonakos N, Nuesch-Germano M, Gkizeli K, Bonaguro L, Reusch N, Baßler K, Saridaki M, Knoll R, Pecht T, Kapellos TS, Doulou S, Kröger C, Herbert M, Holsten L, Horne A, Gemünd ID, Rovina N, Agrawal S, Dahm K, van Uelft M, Drews A, Lenkeit L, Bruse N, Gerretsen J, Gierlich J, Becker M, Händler K, Kraut M, Theis H, Mengiste S, De Domenico E, Schulte-Schrepping J, Seep L, Raabe J, Hoffmeister C, ToVinh M, Keitel V, Rieke G, Talevi V, Skowasch D, Aziz NA, Pickkers P, van de Veerdonk FL, Netea MG, Schultze JL, Kox M, Breteler MMB, Nattermann J, Koutsoukou A, Giamarellos-Bourboulis EJ, Ulas T; German COVID-19 Omics Initiative (DeCOI). Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients. Genome Med. 2021 Jan 13;13(1):7. https://doi.org/10.1186/s13073-020-00823-5.

    4. Falck-Jones S , Vangeti S , Yu M  et al.   PREPRINT: functional myeloid-derived suppressor cells expand in blood but not airways of COVID-19 patients and predict disease severity. medRxiv  2020. doi:10.1101/2020.09.08.20190272.

      Falck-Jones S, Vangeti S, Yu M, Falck-Jones R, Cagigi A, Badolati I, Österberg B, Lautenbach MJ, Ahlberg E, Lin A, Lepzien R, Szurgot I, Lenart K, Hellgren F, Maecker HT, Sälde J, Albert J, Johansson N, Bell M, Lore K, Färnert A, Smed-Sörensen A. Functional monocytic myeloid-derived suppressor cells increase in blood but not airways and predict COVID-19 severity. J Clin Invest. 2021 Jan 25:144734. https://doi.org/10.1172/JCI144734

    5. Lombardi A , Trombetta E , Cattaneo A  et al.   PREPRINT: early phases of COVID-19 are characterized by a reduction of lymphocyte populations and the presence of atypical monocytes. medRxiv  2020. doi:10.1101/2020.05.01.20087080.

      Lombardi A, Trombetta E, Cattaneo A, Castelli V, Palomba E, Tirone M, Mangioni D, Lamorte G, Manunta M, Prati D, Ceriotti F, Gualtierotti R, Costantino G, Aliberti S, Scaravilli V, Grasselli G, Gori A, Porretti L and Bandera A (2020) Early Phases of COVID-19 Are Characterized by a Reduction in Lymphocyte Populations and the Presence of Atypical Monocytes . Front. Immunol. 11:560330. https://doi.org/10.3389/fimmu.2020.560330

    6. Vietzen H , Zoufaly A , Traugott M  et al.   PREPRINT: NK cell receptor NKG2C deletion and HLA-E variants are risk factors for severe COVID-19. Res Square  2020. doi:10.21203/rs.3.rs-34505/v1.

      Vietzen H, Zoufaly A, Traugott M, Aberle J, Aberle SW, Puchhammer-Stöckl E. Deletion of the NKG2C receptor encoding KLRC2 gene and HLA-E variants are risk factors for severe COVID-19. Genet Med. 2021 Jan 26:1–5. https://doi.org/10.1038/s41436-020-01077-7

    7. Zhou Q , Wei X-S , Xiang X  et al.   PREPRINT: Interferon-a2b treatment for COVID-19. medRxiv  2020:2020.04.06.20042580.

      Zhou Q, Chen V, Shannon CP, Wei X-S, Xiang X, Wang X, Wang Z-H, Tebbutt SJ, Kollmann TR and Fish EN (2020) Interferon-α2b Treatment for COVID-19. Front. Immunol. 11:1061. https://doi.org/10.3389/fimmu.2020.01061

    8. Simadibrata DM , Calvin J , Wijaya AD  et al.   PREPRINT: neutrophil-to-lymphocyte ratio on admission to predict the severity and mortality of COVID-19 patients: a meta-analysis. medRxiv  2020. doi:10.1101/2020.09.14.20191098.

      Simadibrata DM, Calvin J, Wijaya AD, Ibrahim NAA. Neutrophil-to-lymphocyte ratio on admission to predict the severity and mortality of COVID-19 patients: A meta-analysis. The American Journal of Emergency Medicine. 2021; 42: 60– 69. https://doi.org/10.1016/j.ajem.2021.01.006.

    9. Zhang D , Guo R , Lei L  et al.   PREPRINT: COVID-19 infection induces readily detectable morphological and inflammation-related phenotypic changes in peripheral blood monocytes, the severity of which correlate with patient outcome. medRxiv  2020. doi:10.1101/2020.03.24.20042655.

      Zhang, D, Guo, R, Lei, L, et al. COVID‐19 infection induces readily detectable morphological and inflammation‐related phenotypic changes in peripheral blood monocytes. J Leukoc Biol. 2021; 109: 13– 22. https://doi.org/10.1002/JLB.4HI0720-470R