Transparent Peer Review
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- reviews
- authors' reply
- editorial decisions
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SV-AUC
Sedimentation Velocity Analytical Ultracentrifugation
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The two binding partners must be in identical buffersto minimize heats of dilution
must be in identical buffer to minimize dilution heat
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The thermophoresis of a fluorescently labeled molecule A
fluorescent label is needed? here the molecule A is protein or ligand?
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by attaching acceptor and donor to different domains of a target protein, the interdomain dynamics can be monitored
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McCulloch and Pitts wrote up their findings in a now-seminal paper, “A Logical Calculus of Ideas Immanent in Nervous Activity,” published in the Bulletin of Mathematical Biophysics.
reference at: https://link.springer.com/article/10.1007%2FBF02478259