213 Matching Annotations
  1. Dec 2025
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    Conformational change of the Plasmodium TRAP I domain is essential for sporozoite migration and transmission of malaria
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    biorxiv.org/lookup/doi/10.1101/2022.08.24.505106
  3. Nov 2025
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    Bassoon controls synaptic vesicle pools via regulation of presynaptic phosphorylation and cAMP homeostasis
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    biorxiv.org/lookup/doi/10.1101/2021.07.22.453360
  5. May 2025
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    LTK and ALK regulate neuronal polarity and cortical migration by modulating IGF1R activity
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    biorxiv.org/content/10.1101/2023.01.29.526107v1
  7. Nov 2024
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    Nutritional status and fecundity are synchronised by muscular exopheresis
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    biorxiv.org/content/10.1101/2020.06.17.157230v2
  9. Sep 2024
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    The mitotic surveillance pathway requires PLK1-dependent 53BP1 displacement from kinetochores
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    biorxiv.org/lookup/doi/10.1101/2023.03.27.534346
  11. Mar 2024
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    The P4-ATPase Drs2 regulates the homeostasis of Atg9
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    biorxiv.org/content/10.1101/2020.12.25.417865v3
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    A YTHDF-PABP axis is required for m6A-mediated organogenesis in plants
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    biorxiv.org/content/10.1101/2023.07.03.547513v2
  14. Jan 2024
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    Convergent Insulin and TGF-β signalling drives cancer cachexia by promoting aberrant fatbody ECM accumulation in a Drosophila tumour model
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    biorxiv.org/content/10.1101/2023.06.10.544444v1
  16. Dec 2023
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    The 5:2 diet does not increase adult hippocampal neurogenesis or enhance spatial memory in mice
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    biorxiv.org/content/10.1101/2022.10.03.510613v1
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    Adult neural stem cells and neurogenesis are resilient to intermittent fasting
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    biorxiv.org/content/10.1101/2022.07.08.499318v2
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    Molecular view of ER membrane remodeling by the Sec61/TRAP translocon
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    biorxiv.org/content/10.1101/2022.09.30.510141v1
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    Recognition of centromere-specific histone Cse4 by the inner kinetochore Okp1-Ame1 complex
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    biorxiv.org/content/10.1101/2023.06.06.543957v1
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    Protein phosphatase 1 regulates core PCP signaling
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    biorxiv.org/content/10.1101/2023.09.12.556998v1
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    Blood flow diverts extracellular vesicles from endothelial degradative compartments to promote angiogenesis
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    biorxiv.org/content/10.1101/2022.12.19.521008v1
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    Circadian oscillation in primary cilium length by clock genes regulate fibroblast cell migration
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    biorxiv.org/content/10.1101/2023.01.24.525311v2
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    The nucleolar protein GNL3 prevents resection of stalled replication forks.
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    biorxiv.org/content/10.1101/2022.10.27.514025v2
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    Monomeric agonist peptide/MHCII complexes activate T-cells in an autonomous fashion
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    biorxiv.org/content/10.1101/2023.03.13.532401v1
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    DONSON is required for CMG helicase assembly in the mammalian cell cycle
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    biorxiv.org/content/10.1101/2023.08.16.553614v1
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    Tetraspanner-based nanodomains modulate BAR domain-induced membrane curvature
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    biorxiv.org/content/10.1101/2022.11.21.517310v1
  28. Nov 2023
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    SARS-CoV-2 ORF3c suppresses immune activation by inhibiting innate sensing
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    biorxiv.org/content/10.1101/2023.02.27.530232v2
  30. www.biorxiv.org www.biorxiv.org
    Tick-borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK2
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    biorxiv.org/content/10.1101/2023.09.07.556670v1
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    http://biorxiv.org/cgi/content/short/2021.01.06.425396
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    biorxiv.org/content/10.1101/2021.01.06.425396v2
  32. www.biorxiv.org www.biorxiv.org
    Enhanced Airway Epithelial Response to SARS-CoV-2 Infection in Children is Critically Tuned by the Cross-Talk Between Immune and Epithelial Cells
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    biorxiv.org/content/10.1101/2023.05.17.541103v1
  33. Sep 2023
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    Fasting-sensitive SUMO-switch on Prox1 controls hepatic cholesterol metabolism
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    biorxiv.org/content/10.1101/2022.08.17.504229v1
  35. www.biorxiv.org www.biorxiv.org
    Interferon inhibits a model RNA virus via a limited set of inducible effector genes
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    biorxiv.org/content/10.1101/2023.02.21.529297v1
  36. www.biorxiv.org www.biorxiv.org
    Branched chain amino acid synthesis is coupled to TOR activation early in the cell cycle in yeast
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    biorxiv.org/content/10.1101/2023.01.10.523468v2
  37. www.biorxiv.org www.biorxiv.org
    Calculating ATP production rates from oxidative phosphorylation and glycolysis during cell activation
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    biorxiv.org/content/10.1101/2022.04.16.488523v2
  38. www.biorxiv.org www.biorxiv.org
    Myddosome clustering in IL-1 receptor signaling regulates the formation of an NF-kB activating signalosome
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    biorxiv.org/content/10.1101/2023.01.06.522894v2
  39. Aug 2023
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    PRMT5 links lipid metabolism to contractile function of skeletal muscles
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    biorxiv.org/content/10.1101/2022.11.04.515165v1
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    Terminal differentiation of enterocytes is governed by distinct members of Tgfβ superfamily
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    biorxiv.org/content/10.1101/2022.11.11.516138v2
  42. Jul 2023
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    DOT1L bridges transcription and heterochromatin formation at pericentromeres
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    biorxiv.org/content/10.1101/2021.10.21.465349v1
  44. www.biorxiv.org www.biorxiv.org
    PARK15/FBXO7 is dispensable for PINK1/Parkin-dependent mitophagy in iNeuron and HeLa cell systems
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    biorxiv.org/content/10.1101/2022.11.02.514817v2
  45. www.biorxiv.org www.biorxiv.org
    MATR3-antisense LINE1 RNA meshwork scaffolds higher-order chromatin organization
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    biorxiv.org/content/10.1101/2022.09.13.506124v1
  46. www.biorxiv.org www.biorxiv.org
    ENGRAILED-1 transcription factor exerts a paracrine neurotrophic activity on adult spinal cord α-motoneurons.
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    biorxiv.org/content/10.1101/2022.08.16.504081v3
  47. Jun 2023
  48. www.biorxiv.org www.biorxiv.org
    Tmem117 in AVP neurons regulates the counterregulatory response to hypoglycemia
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    biorxiv.org/content/10.1101/2022.10.21.513159v3
  49. www.biorxiv.org www.biorxiv.org
    The histone methyltransferase DOT1L regulates chromatin reorganization and gene expression during the postmeiotic differentiation of male germ cells
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    biorxiv.org/content/10.1101/2022.10.17.512530v2
  50. May 2023
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    A quantitative fluorescence-based approach to study mitochondrial protein import
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    biorxiv.org/content/10.1101/2022.10.10.511594v1
  52. www.biorxiv.org www.biorxiv.org
    Ubiquitination occurs in the mitochondrial matrix by eclipsed components of the ubiquitin machinery
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    biorxiv.org/content/10.1101/2022.07.10.499450v2
  53. www.biorxiv.org www.biorxiv.org
    The transcriptional regulator Sin3A balances IL-17A and Foxp3 expression in primary CD4 T cells
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    biorxiv.org/content/10.1101/2022.04.19.488789v1
  54. www.biorxiv.org www.biorxiv.org
    Inhibition of the ATM kinase rescues planarian regeneration after lethal radiation
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    biorxiv.org/content/10.1101/2022.09.28.509579v1
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    Endothelial FOXC1 and FOXC2 promote intestinal regeneration after ischemia-reperfusion injury
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    biorxiv.org/content/10.1101/2022.03.03.482713v2
  56. www.biorxiv.org www.biorxiv.org
    The piRNA pathway sustains adult neurogenesis by repressing protein synthesis
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    biorxiv.org/content/10.1101/2020.09.15.297739v2
  57. www.biorxiv.org www.biorxiv.org
    Caspase-dependent activation of Hedgehog-signalling sustains proliferation and differentiation of ovarian somatic stem cells.
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    biorxiv.org/content/10.1101/722330v3
  58. Apr 2023
  59. www.biorxiv.org www.biorxiv.org
    UBAP2L-dependent coupling of PLK1 localization and stability during mitosis
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    biorxiv.org/content/10.1101/2022.10.24.513562v2
  60. www.biorxiv.org www.biorxiv.org
    Deregulations of miR-1 and its target Multiplexin promote dilated cardiomyopathy associated with myotonic dystrophy type 1
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    biorxiv.org/content/10.1101/2022.09.06.506816v1
  61. www.biorxiv.org www.biorxiv.org
    Morphofunctional changes at the active zone during synaptic vesicle exocytosis
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    biorxiv.org/content/10.1101/2022.03.07.483217v2
  62. Mar 2023
  63. www.biorxiv.org www.biorxiv.org
    Mild impairment of mitochondrial function increases longevity and pathogen resistance through ATFS-1-driven activation of p38-regulated innate immunity
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    biorxiv.org/content/10.1101/2021.03.31.437812v1
  64. www.biorxiv.org www.biorxiv.org
    Rabaptin5 targets autophagy to damaged early endosomes and Salmonella containing vacuoles by interaction with FIP200 and ATG16L1
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    biorxiv.org/content/10.1101/2020.09.01.277764v2
  65. www.biorxiv.org www.biorxiv.org
    Protein-coding potential of RNAs measured by potentially translated island scores
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    biorxiv.org/content/10.1101/2021.04.14.439730v2
  66. www.biorxiv.org www.biorxiv.org
    Production of offspring from azoospermic mice with meiotic failure: Precise biparental meiosis within halved oocytes
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    biorxiv.org/content/10.1101/2021.09.03.458818v4
  67. www.biorxiv.org www.biorxiv.org
    The Legionella-driven PtdIns(4)P gradient at LCV-ER membrane contact sites promotes Vap-, OSBP- and Sac1-dependent pathogen vacuole remodeling
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    biorxiv.org/content/10.1101/2022.06.17.496549v2
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    The spindle orienting machinery requires activation, not just localization
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    biorxiv.org/content/10.1101/2022.06.29.498167v1
  69. www.biorxiv.org www.biorxiv.org
    Multinucleation resets human macrophages for specialized functions at the expense of mononuclear phagocyte identity
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    biorxiv.org/content/10.1101/2022.08.22.504763v1
  70. Feb 2023
  71. www.biorxiv.org www.biorxiv.org
    The mechanosensitive TRPV2 calcium channel controls melanoma invasiveness and metastatic potential.
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    biorxiv.org/content/10.1101/2021.10.22.465391v1
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    Single cell clonal analysis identifies an AID-dependent pathway of plasma cell differentiation
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    biorxiv.org/content/10.1101/2021.06.03.446763v1
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    Cryo-EM structure of the octameric pore of Clostridium perfringens β-toxin
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    biorxiv.org/content/10.1101/2021.11.23.469684v2
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    CDK9 and PP2A regulate the link between RNA polymerase II transcription termination and RNA maturation.
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    biorxiv.org/content/10.1101/2021.06.21.449289v3
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    Constricted migration contributes to persistent 3D genome structure changes associated with an invasive phenotype in melanoma cells
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    biorxiv.org/content/10.1101/856583v3
  76. www.biorxiv.org www.biorxiv.org
    NuRD independent Mi-2 activity represses ectopic gene expression during neuronal maturation.
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    biorxiv.org/content/10.1101/2022.04.19.488642v3
  77. Jan 2023
  78. www.biorxiv.org www.biorxiv.org
    CDK8 and CDK19 act redundantly to control the CFTR pathway in the intestinal epithelium
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    biorxiv.org/content/10.1101/2022.01.28.478171v1
  79. Dec 2022
  80. www.biorxiv.org www.biorxiv.org
    Adaptation delay causes a burst of mutations in bacteria responding to oxidative stress
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    biorxiv.org/content/10.1101/2022.05.25.493234v1
  81. www.biorxiv.org www.biorxiv.org
    Specific N-glycans regulate an extracellular adhesion complex during somatosensory dendrite patterning
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    biorxiv.org/content/10.1101/2021.10.11.464022v1
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    The dengue virus NS1 protein conveys pro-inflammatory signals by docking onto human high-density lipoproteins
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    biorxiv.org/content/10.1101/2021.05.05.442454v1
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    Dissecting the co-transcriptome landscape of plants and microbiota members
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    biorxiv.org/content/10.1101/2021.04.25.440543v2
  84. Nov 2022
  85. www.biorxiv.org www.biorxiv.org
    The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging
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    biorxiv.org/content/10.1101/2022.02.28.482241v1
  86. www.biorxiv.org www.biorxiv.org
    The AAA-ATPase Atad1 and its partners promote degradation of desmin intermediate filaments in muscle
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    biorxiv.org/content/10.1101/2022.01.24.477493v2
  87. www.biorxiv.org www.biorxiv.org
    Live-cell chromosome dynamics in Arabidopsis thaliana reveals increased chromatin mobility in response to DNA damage
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    biorxiv.org/content/10.1101/2021.11.03.466744v2
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    The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins
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    biorxiv.org/content/10.1101/2022.08.18.504437v1
  89. www.biorxiv.org www.biorxiv.org
    Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair
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    biorxiv.org/content/10.1101/2020.08.24.265033v1
  90. www.biorxiv.org www.biorxiv.org
    http://biorxiv.org/cgi/content/short/2020.11.10.376822
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    biorxiv.org/content/10.1101/2020.11.10.376822v2
  91. www.biorxiv.org www.biorxiv.org
    Dynamic chromosomal interactions and control of heterochromatin positioning by Ki67
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    biorxiv.org/content/10.1101/2021.10.20.465140v2
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    The chromatin factor ROW cooperates with BEAF-32 in regulating long-range genes
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    biorxiv.org/content/10.1101/2021.03.08.434270v3
  93. www.biorxiv.org www.biorxiv.org
    Parkin drives pS65-Ub turnover independently of canonical autophagy in Drosophila
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    biorxiv.org/content/10.1101/2021.06.10.447841v2
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    Parkin coordinates mitochondrial lipid remodeling to execute mitophagy
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    biorxiv.org/content/10.1101/2020.02.28.970210v1
  95. www.biorxiv.org www.biorxiv.org
    Endothelial-immune crosstalk contributes to vasculopathy in non-alcoholic fatty liver disease
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    biorxiv.org/content/10.1101/2021.12.13.472411v1
  96. www.biorxiv.org www.biorxiv.org
    Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc
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    biorxiv.org/content/10.1101/2021.09.11.459911v1
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    http://biorxiv.org/cgi/content/short/2020.10.28.359356
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    biorxiv.org/content/10.1101/2020.10.28.359356v4
  98. www.biorxiv.org www.biorxiv.org
    Autophagic state prospectively identifies facultative stem cells in the intestinal epithelium
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    biorxiv.org/content/10.1101/2022.04.08.487404v1
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    Zika virus alters centrosome organization to suppress the innate immune response
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    biorxiv.org/content/10.1101/2020.09.15.298083v1
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    https://biorxiv.org/cgi/content/10.1101/2021.02.25.432821
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    biorxiv.org/content/10.1101/2021.02.25.432821v3
  101. www.biorxiv.org www.biorxiv.org
    Mechanistic insights into the enhancement or inhibition of phase separation by polyubiquitin chains of different lengths or linkages
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    biorxiv.org/content/10.1101/2021.11.12.467822v2
  102. www.biorxiv.org www.biorxiv.org
    Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6-dependent pathway
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    biorxiv.org/content/10.1101/2021.10.06.463323v1
  103. www.biorxiv.org www.biorxiv.org
    Basal Neural Stem Cells in the Subventricular Zone Drive Postnatal Neurogenesis with Apical Stem Cells Acting as Proliferation Gatekeepers
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    biorxiv.org/content/10.1101/2020.11.20.391102v4
  104. www.biorxiv.org www.biorxiv.org
    Lifespan can be extended during a specific time window early in life
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    biorxiv.org/content/10.1101/2022.02.18.480980v1
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    IL-21 lowers the B cell receptor affinity threshold for participation in a T cell dependent immune response.
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    biorxiv.org/content/10.1101/2022.01.21.476732v2
  106. www.biorxiv.org www.biorxiv.org
    Nanoengineered DNA origami with repurposed TOP1 inhibitors targeting myeloid cells for the mitigation of neuroinflammation
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    biorxiv.org/content/10.1101/2021.10.04.462880v1
  107. www.biorxiv.org www.biorxiv.org
    Structural mechanism underpinning Thermus oshimai Pif1-mediated G-quadruplex unfolding
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  201. Oct 2020
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  208. Jul 2020
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    An early Myc-dependent transcriptional program underlies enhanced macromolecular biosynthesis and cell growth during B-cell activation
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    biorxiv.org/content/10.1101/561464v2
  213. www.biorxiv.org www.biorxiv.org
    The multi PAM2 protein Upa2 functions as novel core component of endosomal mRNA transport
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    biorxiv.org/content/10.1101/455378v2
  214. www.biorxiv.org www.biorxiv.org
    Radial F-actin Organization During Early Neuronal Development
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    biorxiv.org/content/10.1101/372813v2
  215. www.biorxiv.org www.biorxiv.org
    TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease
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    biorxiv.org/content/10.1101/634519v1
  216. www.biorxiv.org www.biorxiv.org
    Characterisation of the c10orf76-PI4KB complex, and its necessity for Golgi PI4P levels and enterovirus replication
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    biorxiv.org/content/10.1101/634592v1
  217. www.biorxiv.org www.biorxiv.org
    Apicomplexan F-actin is required for efficient nuclear entry during host cell invasion
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    biorxiv.org/content/10.1101/646463v1
  218. www.biorxiv.org www.biorxiv.org
    Targeted gene correction of FKRP by CRISPR/Cas9 restores functional glycosylation of α-dystroglycan in cortical neurons derived from human induced pluripotent stem cells
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    biorxiv.org/content/10.1101/101352v1
  219. Jun 2020
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    Metabolic Energy Sensing by Mammalian CLC Anion/Proton Exchangers
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    biorxiv.org/content/10.1101/545368v1
  221. www.biorxiv.org www.biorxiv.org
    Gi-Coupled Receptor Activation Potentiates Piezo2 Currents via Gβγ
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    biorxiv.org/content/10.1101/722637v1
  222. www.biorxiv.org www.biorxiv.org
    Controlling the Mitochondrial Protonmotive Force with Light to Impact Cellular Stress Resistance
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    biorxiv.org/content/10.1101/742536v1
  223. www.biorxiv.org www.biorxiv.org
    The mitochondrial Rho-GTPase, Miro, is resident at peroxisomes and regulates peroxisomal trafficking and morphology
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    biorxiv.org/content/10.1101/241208v1
  224. www.biorxiv.org www.biorxiv.org
    Cristae undergo continuous cycles of fusion and fission in a MICOS-dependent manner
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    biorxiv.org/content/10.1101/654541v1
  225. Nov 2019
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    Pannexin-1 Channels govern the Generation of Necroptotic small Extracellular Vesicles
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    biorxiv.org/content/10.1101/537753v1
  227. www.biorxiv.org www.biorxiv.org
    S-acylated Golga7b stabilises DHHC5 at the plasma membrane to regulate desmosome assembly and cell adhesion.
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    biorxiv.org/content/10.1101/481861v1
  228. www.biorxiv.org www.biorxiv.org
    Elucidation of the viral disassembly switch of tobacco mosaic virus
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    biorxiv.org/content/10.1101/569178v1
  229. Sep 2019
  230. www.biorxiv.org www.biorxiv.org
    The β3-integrin endothelial adhesome regulates microtubule dependent cell migration
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    biorxiv.org/content/10.1101/145839v1
  231. www.biorxiv.org www.biorxiv.org
    A genetic system for generating single-sex progeny in mice
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    biorxiv.org/content/10.1101/515064v2
  232. www.biorxiv.org www.biorxiv.org
    Multiple C2 domains and Transmembrane region Proteins (MCTPs) tether membranes at plasmodesmata
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    biorxiv.org/content/10.1101/423905v1
  233. www.biorxiv.org www.biorxiv.org
    Euchromatic histone methyltransferases regulate peripheral heterochromatin tethering via histone and non-histone protein methylations
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    biorxiv.org/content/10.1101/240952v2
  234. www.biorxiv.org www.biorxiv.org
    Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice
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    The nucleoporin ELYS regulates nuclear size by controlling NPC number and nuclear import capacity
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    biorxiv.org/content/10.1101/510230v1
  236. www.biorxiv.org www.biorxiv.org
    SWI/SNF chromatin remodeling controls Notch-responsive enhancer accessibility
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    biorxiv.org/content/10.1101/399501v1
  237. www.biorxiv.org www.biorxiv.org
    Structural basis of HEAT-kleisin interactions in the human condensin I subcomplex
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    biorxiv.org/content/10.1101/435149v1
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    The fungal root endophyte Serendipita indica modifies extracellular nucleotides to subvert plant immunity
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    biorxiv.org/content/10.1101/396028v1
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    The key protein of endosomal mRNP transport binds translational landmark sites of cargo mRNAs
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    biorxiv.org/content/10.1101/418079v2