4 Matching Annotations
  1. May 2019
    1. When geneticists finally gained the power to cost-efficiently analyze entire genomes, they realized that most disorders and diseases are influenced by thousands of genes, each of which has a tiny effect. To reliably detect these miniscule effects, you need to compare hundreds of thousands of volunteers. By contrast, the candidate-gene studies of the 2000s looked at an average of 345 people!

      I'm hoping that more researchers are contemplating this as they stroll merrily along their way this week.

  2. Apr 2017
    1. I have had IBS essentially all my life. At least as far back as I can remember. This is a very interesting experiement. Hopefully scientists can use this as a springboard for either further research, or ideally, to find a solution. IBS negatively impacts quality of life for many sufferers.

      Isn't the flipped experiment a clear indication that FTT (fecal transplant therapy) can help alleviating IBS? If the reverse is true, there might be great value in getting your microbiome fixed/infused by healthy microbiota from donors.

  3. Apr 2016
  4. Feb 2015
    1. Positive-stranded RNA viruses: I went to a retro (retrovirus) toga (togavirus) party, where I drank flavored (flavivirus) Corona (coronavirus) and ate hippy (hepevirus) California (calicivirus) pickles (picornavirus).

      I would add "positively fun" to the mnemonic for positive-stranded RNA viruses, so it reads, "I went to a POSITIVELY FUN retro toga party, where I drank flavored Corona and ate hippy California pickles.