304 Matching Annotations
  1. Dec 2024
  2. www.biorxiv.org www.biorxiv.org
    Structural basis for inhibition of mycobacterial ATP synthase by squaramides and second generation diarylquinolines
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    1. EMBOpress 03 Dec 2024

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    biorxiv.org/content/10.1101/2023.02.03.527018v1
  3. Nov 2024
  4. www.biorxiv.org www.biorxiv.org
    An auto-release mechanism for HMCES-DNA-protein crosslinks
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    1. EMBOpress 26 Nov 2024

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    biorxiv.org/content/10.1101/2022.12.18.520715v1
  5. Aug 2024
  6. www.biorxiv.org www.biorxiv.org
    Multi-modal adaptor-clathrin contacts drive coated vesicleassembly
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    1. EMBOpress 20 Aug 2024

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    biorxiv.org/content/10.1101/2021.05.22.445240v1
  7. May 2024
  8. www.biorxiv.org www.biorxiv.org
    Control of mammalian brain aging by the unfolded protein response (UPR)
    1
    1. EMBOpress 22 May 2024

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    biorxiv.org/content/10.1101/2020.04.13.039172v1
  9. Apr 2024
  10. www.biorxiv.org www.biorxiv.org
    Condensate functionalization with motors directs their nucleation in space and allows manipulating RNA localization
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    1. EMBOpress 23 Apr 2024

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    biorxiv.org/content/10.1101/2022.07.10.499452v1
  11. Mar 2024
  12. www.biorxiv.org www.biorxiv.org
    Plant YTHDF proteins are direct effectors of antiviral immunity against an m6A-containing RNA virus
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    1. EMBOpress 20 Mar 2024

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    biorxiv.org/content/10.1101/2022.10.19.512835v1
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    Regulation of branched versus linear Arp2/3-generated actin filaments
    1
    1. EMBOpress 07 Mar 2024

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    biorxiv.org/content/10.1101/2022.05.06.490861v1
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    Extracellular vesicles and co-isolated endogenous retroviruses differently affect dendritic cells
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    1. EMBOpress 06 Mar 2024

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    biorxiv.org/content/10.1101/2023.01.27.525863v1
  15. Feb 2024
  16. www.biorxiv.org www.biorxiv.org
    Cryo-EM structure of lipid embedded human ABCA7 at 3.6 &Aring resolution
    1
    1. EMBOpress 27 Feb 2024

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    biorxiv.org/content/10.1101/2021.03.01.433448v2
  17. www.biorxiv.org www.biorxiv.org
    Pioneer activity distinguishes activating from non-activating pluripotency transcription factor binding sites
    1
    1. EMBOpress 07 Feb 2024

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    biorxiv.org/content/10.1101/2022.07.27.501606v1
  18. Jan 2024
  19. www.biorxiv.org www.biorxiv.org
    Human liver organoids model progressive inflammatory and fibrotic injury in non-alcoholic fatty liver disease
    1
    1. EMBOpress 17 Jan 2024

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    biorxiv.org/content/10.1101/2022.07.19.500693v2
  20. www.biorxiv.org www.biorxiv.org
    Arp2/3 inhibition switches Eps8’s network associations to favour longer actin filament formation necessary for tunneling nanotubes
    1
    1. EMBOpress 06 Jan 2024

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    biorxiv.org/content/10.1101/2022.08.24.504515v2
  21. Dec 2023
  22. www.biorxiv.org www.biorxiv.org
    Monomeric α-Synuclein activates the Plasma Membrane Calcium Pump
    1
    1. EMBOpress 19 Dec 2023

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    biorxiv.org/content/10.1101/2022.02.21.481193v2
  23. www.biorxiv.org www.biorxiv.org
    Adaptive Pathfinding by Nucleokinesis during Amoeboid Migration
    1
    1. EMBOpress 15 Dec 2023

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    biorxiv.org/content/10.1101/2023.05.19.540965v1
  24. www.biorxiv.org www.biorxiv.org
    The ribosome-associated chaperone Zuo1 controls translation upon TORC1 inhibition
    1
    1. EMBOpress 15 Dec 2023

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    biorxiv.org/content/10.1101/2022.12.09.519716v1
  25. www.biorxiv.org www.biorxiv.org
    The Response of the Eukaryotic Replisome to G-quadruplex- and i-motif-forming Sequences
    1
    1. EMBOpress 13 Dec 2023

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    biorxiv.org/content/10.1101/2022.11.18.517070v2
  26. www.biorxiv.org www.biorxiv.org
    Thiol reductive stress activates the hypoxia response pathway
    1
    1. EMBOpress 13 Dec 2023

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    biorxiv.org/content/10.1101/2023.03.06.531274v2
  27. www.biorxiv.org www.biorxiv.org
    YAP antagonizes TEAD-mediated AR signaling and prostate cancer growth
    1
    1. EMBOpress 01 Dec 2023

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      PeerReviewed EMBOPress The EMBO Journal cancer biology
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    biorxiv.org/content/10.1101/2022.08.01.502314v1
  28. Nov 2023
  29. www.biorxiv.org www.biorxiv.org
    A bifunctional kinase-phosphatase module integrates mitotic checkpoint and error-correction signalling to ensure mitotic fidelity
    1
    1. EMBOpress 30 Nov 2023

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    biorxiv.org/content/10.1101/2022.05.22.492960v2
  30. www.biorxiv.org www.biorxiv.org
    Vimentin intermediate filaments organize organellar architecture in response to ER stress
    1
    1. EMBOpress 28 Nov 2023

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    biorxiv.org/content/10.1101/2022.03.24.485587v1
  31. www.biorxiv.org www.biorxiv.org
    A region-resolved proteomic map of the human brain enabled by high-throughput proteomics
    1
    1. EMBOpress 21 Nov 2023

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    biorxiv.org/content/10.1101/2023.06.05.543676v1
  32. www.biorxiv.org www.biorxiv.org
    Comprehensive comparison of female germ cell development in vitro and in vivo identifies epigenetic gene regulation crucial for oocyte development and embryonic competence
    1
    1. EMBOpress 17 Nov 2023

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    biorxiv.org/content/10.1101/2023.02.15.528760v1
  33. www.biorxiv.org www.biorxiv.org
    A network of small RNAs regulates sporulation initiation in C. difficile
    1
    1. EMBOpress 15 Nov 2023

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    biorxiv.org/content/10.1101/2022.10.17.512509v1
  34. Oct 2023
  35. www.biorxiv.org www.biorxiv.org
    EMBRYO-UTERINE INTERACTION COORDINATES MOUSE EMBRYOGENESIS DURING IMPLANTATION
    1
    1. EMBOpress 05 Oct 2023

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    biorxiv.org/content/10.1101/2022.06.13.495767v1
  36. Sep 2023
  37. www.biorxiv.org www.biorxiv.org
    Mechanisms and physiological function of daily haemoglobin oxidation rhythms in red blood cells
    1
    1. EMBOpress 06 Sep 2023

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    biorxiv.org/content/10.1101/2021.10.11.463714v2
  38. www.biorxiv.org www.biorxiv.org
    PTEN deficiency exposes a requirement for an ARF GTPase module in integrin-dependent invasion in ovarian cancer.
    1
    1. EMBOpress 06 Sep 2023

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    biorxiv.org/content/10.1101/2022.11.29.518198v1
  39. www.biorxiv.org www.biorxiv.org
    A Sterol-PI(4)P exchanger controls the Tel1/ATM axis of the DNA Damage Response
    1
    1. EMBOpress 02 Sep 2023

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    biorxiv.org/content/10.1101/2022.07.13.499867v1
  40. www.biorxiv.org www.biorxiv.org
    Phosphorylation controls spatial and temporal activities of motor-PRC1 complexes to complete mitosis
    1
    1. EMBOpress 01 Sep 2023

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    biorxiv.org/content/10.1101/2023.03.11.531660v1
  41. Aug 2023
  42. www.biorxiv.org www.biorxiv.org
    Randomly incorporated genomic 6mA delays zygotic transcription initiation
    1
    1. EMBOpress 25 Aug 2023

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    biorxiv.org/content/10.1101/2022.10.27.514014v1
  43. www.biorxiv.org www.biorxiv.org
    Senescent cell death as an aging resistance mechanism in naked mole-rat
    1
    1. EMBOpress 04 Aug 2023

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    biorxiv.org/content/10.1101/2020.07.02.155903v1
  44. www.biorxiv.org www.biorxiv.org
    Synaptotagmin 1 mediates toxicity of botulinum neurotoxin type A
    1
    1. EMBOpress 04 Aug 2023

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    biorxiv.org/content/10.1101/2022.02.28.482398v1
  45. www.biorxiv.org www.biorxiv.org
    Direct observation of coordinated assembly of individual native centromeric nucleosomes
    1
    1. EMBOpress 03 Aug 2023

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    biorxiv.org/content/10.1101/2023.01.20.524981v2
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    Evolutionary transcriptomics reveals longevity mostly driven by polygenic and indirect selection in mammals
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    1. EMBOpress 02 Aug 2023

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    biorxiv.org/content/10.1101/2023.01.09.523139v1
  47. Jul 2023
  48. www.biorxiv.org www.biorxiv.org
    Characterization of the REC114-MEI4-IHO1 complex regulating meiotic DNA double-strand break formation
    1
    1. EMBOpress 29 Jul 2023

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    biorxiv.org/content/10.1101/2023.01.11.523614v1
  49. www.biorxiv.org www.biorxiv.org
    Ribonucleotide synthesis by NME6 fuels mitochondrial gene expression
    1
    1. EMBOpress 28 Jul 2023

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    biorxiv.org/content/10.1101/2022.11.29.518352v1
  50. www.biorxiv.org www.biorxiv.org
    Cohesin-mediated DNA loop extrusion resolves sister chromatids in G2 phase
    1
    1. EMBOpress 15 Jul 2023

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    biorxiv.org/content/10.1101/2023.01.12.523718v1
  51. www.biorxiv.org www.biorxiv.org
    Centrosome amplification fine-tunes tubulin acetylation to differentially control intracellular organization
    1
    1. EMBOpress 13 Jul 2023

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    biorxiv.org/content/10.1101/2022.10.17.512471v1
  52. Jun 2023
  53. www.biorxiv.org www.biorxiv.org
    HNRNPH1 regulates the neuroprotective cold-shock protein RBM3 expression through poison exon exclusion
    1
    1. EMBOpress 29 Jun 2023

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    biorxiv.org/content/10.1101/2022.10.27.514062v1
  54. www.biorxiv.org www.biorxiv.org
    Structural basis of ubiquitin-independent PP1 complex disassembly by p97
    1
    1. EMBOpress 29 Jun 2023

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    biorxiv.org/content/10.1101/2022.06.24.497491v1
  55. www.biorxiv.org www.biorxiv.org
    Multivalent BARD1-nucleosome interactions facilitate H2A ubiquitylation by BRCA1/BARD1
    1
    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.08.09.503292v2
  56. www.biorxiv.org www.biorxiv.org
    PERK Signaling Promotes Mitochondrial Elongation By Remodeling Membrane Phosphatidic Acid
    1
    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.02.23.481593v2
  57. www.biorxiv.org www.biorxiv.org
    Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response
    1
    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.12.21.521356v1
  58. www.biorxiv.org www.biorxiv.org
    Pseudomonas aeruginosa mechanosensing controls cell polarity during twitching by activating two antagonistic response regulators
    1
    1. EMBOpress 24 Jun 2023

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    biorxiv.org/content/10.1101/2022.11.15.516588v1
  59. www.biorxiv.org www.biorxiv.org
    Two distinct mechanisms underlie dosage sensitivity in Pumilio1-associated diseases
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    1. EMBOpress 16 Jun 2023

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    biorxiv.org/content/10.1101/2021.03.11.435015v5
  60. www.biorxiv.org www.biorxiv.org
    Stable kinetochore-microtubule attachment requires loop-dependent Ndc80-Ndc80 binding
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    1. EMBOpress 15 Jun 2023

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    biorxiv.org/content/10.1101/2022.08.25.505310v1
  61. www.biorxiv.org www.biorxiv.org
    Deterministic and probabilistic fate decisions co-exist in a single retinal lineage
    1
    1. EMBOpress 10 Jun 2023

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    biorxiv.org/content/10.1101/2022.08.11.503564v1
  62. www.biorxiv.org www.biorxiv.org
    Functionally distinct promoter classes initiate transcription via different mechanisms reflected in focused versus dispersed initiation patterns
    1
    1. EMBOpress 10 Jun 2023

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    biorxiv.org/content/10.1101/2022.09.30.509643v2
  63. May 2023
  64. www.biorxiv.org www.biorxiv.org
    Ubx5-Cdc48 assists the protease Wss1 at DNA-protein crosslink sites in yeast
    1
    1. EMBOpress 25 May 2023

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    biorxiv.org/content/10.1101/2022.05.30.493988v1
  65. www.biorxiv.org www.biorxiv.org
    eIF3 mRNA selectivity profiling reveals eIF3k as a cancer-relevant regulator of ribosome content
    1
    1. EMBOpress 25 May 2023

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    FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors
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    ROR1 plays a critical role in pancreatic tumor-initiating cells with a partial EMT signature.
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    1. EMBOpress 19 May 2023

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    DASH/Dam1 complex mutants stabilize ploidy by weakening kinetochore-microtubule attachments
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  69. Apr 2023
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    TOR acts as metabolic gatekeeper for auxin-dependent lateral root initiation in Arabidopsis thaliana
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    An RNA-binding switch drives ribosome biogenesis and tumorigenesis downstream of RAS oncogene
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    Cell-extrinsic autophagy in mature adipocytes regulates anti-inflammatory response to intestinal tissue injury through lipid mobilization
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    Single cell analysis of lymphatic endothelial cell fate specification and differentiation during zebrafish development
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  74. Mar 2023
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    Hda1C limits divergent non-coding transcription and restricts transcription initiation frequency
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    E-Cadherin mediated AMIS localisation
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    Reconstitution of centrosome positioning by the production of pushing forces in microtubules growing against the actin network.
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    The Grainyhead/LSF transcription factor GRH-1 is rhythmically required for molting
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    Shuffled ATG8 interacting motifs form an ancestral bridge between UFMylation and C53-mediated autophagy
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    An Arrayed Genome-Wide Perturbation Screen Identifies the Ribonucleoprotein hnRNP K As Rate-Limiting for Prion Propagation
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    Uncoupling from transcription protects polyadenylation site cleavage from inhibition by DNA damage
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    The cryo-EM structure of the CENP-A nucleosome in complex with ggKNL2
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    The eukaryotic translation initiation factor eIF4E reprogrammes the splicing machinery anddrives alternative splicing
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    Structure and mechanism of a novel cytomegaloviral DCAF mediating interferon antagonism
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    The Proxitome of Arabidopsis Processing Bodies Reveals a Condensate-Membrane Interface Instructing Actin-Driven Directional Growth
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  86. Feb 2023
  87. www.biorxiv.org www.biorxiv.org
    TORC1 phosphorylates and inhibits the ribosome preservation factor Stm1 to activate dormant ribosomes
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    MitoStores: Chaperone-controlled protein granules store mitochondrial precursors in the cytosol
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    Retromer oligomerization drives SNX-BAR coat assembly and membrane constriction
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    Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis
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    The blood vasculature instructs lymphatics patterning in a SOX7-dependent manner
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    TSC2 regulates tumor susceptibility to TRAIL-mediated T cell killing by orchestrating mTOR signaling
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    Transient ribosome slowdown at the decoding step triggers mRNA degradation independent of Znf598 in zebrafish
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    A molecular mechanism by which amyloid-β induces transcriptional inactivation of CREB in Alzheimer's Disease
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    biorxiv.org/content/10.1101/2020.01.08.898304v3
  95. Jan 2023
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    Plasma membrane topography governs the three-dimensional dynamic localization of IgM B cell receptor clusters
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    Condensin pinches a short negatively supercoiledDNA loop during each round of ATP usage
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  98. Dec 2022
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    When Yeast Cells Change their Mind: Cell Cycle 'Start' is Reversible under Starvation
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    Structural and biochemical basis of FANCI-FANCD2 interdependent ubiquitination
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    Cue-specific remodeling of the neuronal transcriptome through intron retention programs
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  102. Nov 2022
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    The E3 ligase RNF115 regulates phagosome maturation and host response to bacterial infection
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    A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
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    m6A is required for resolving progenitor identity during planarian stem cell differentiation
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    Structure and functional mapping of the KRAB-KAP1 repressor complex
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    Temporal and sequential transcriptional dynamics define lineage shifts in corticogenesis
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    An ERAD-independent role for rhomboid pseudoprotease Dfm1 in mediating sphingolipid homeostasis
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    RNA-mediated nucleosome depletion is required for elimination of transposon-derived DNA.
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    Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity
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    Cellular stress in brain organoids is limited to a distinct and bioinformatically removable subpopulation.
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    HEAT SHOCK FACTOR BINDING PROTEIN limits meiotic crossovers by repressing HEI10 transcription
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    TSG101 Associates with PARP1 and is Essential for PARylation and DNA Damage-induced NF-κB Activation
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    A conserved signaling pathway activates bacterial CBASS immune signaling in response to DNA damage
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    CRYPTOCHROME suppresses the circadian proteome and promotes protein homeostasis
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    biorxiv.org/content/10.1101/2020.05.16.099556v3
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    Naked mole-rat hematopoietic stem and progenitors are highly quiescent with an inherent myeloid bias
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    Regulation of mitochondrial proteostasis by the proton gradient
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    Heterotypic Assembly Mechanism Regulates CHIP E3 Ligase Activity
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    Mitotic checkpoint gene expression is tuned by coding sequences
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    Nuclear Pore Complex Acetylation Regulates mRNA Export and Cell Cycle Commitment in Budding Yeast
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  121. www.biorxiv.org www.biorxiv.org
    Cellular toxicity of iHAP1 and DT-061 does not occur through PP2A-B56 targeting
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  122. www.biorxiv.org www.biorxiv.org
    Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms
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  123. www.biorxiv.org www.biorxiv.org
    Cooperative Amyloid Fibre Binding and Disassembly by the Hsp70 disaggregase
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  124. www.biorxiv.org www.biorxiv.org
    Precise control of microtubule disassembly in living cells
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  125. www.biorxiv.org www.biorxiv.org
    Varicella-Zoster Virus ORF9 Is an Antagonist of the DNA Sensor cGAS
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  126. www.biorxiv.org www.biorxiv.org
    Self-ubiquitination of a pathogen type-III effector traps and blocks the autophagy machinery to promote disease
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  127. www.biorxiv.org www.biorxiv.org
    A temporally controlled sequence of X-chromosomeinactivation and reactivation defines female mouse in vitro germ cells with meiotic potential
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  128. Jun 2022
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    A RIF1 and KAP1-based, double-bookmarking system generates a toggle switch that stabilises the identities of the active and inactive X chromosomes during random X inactivation in mouse
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  130. May 2022
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    Centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly
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  132. www.biorxiv.org www.biorxiv.org
    Structural basis for feedforward control in the PINK1/parkin pathway
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  133. www.biorxiv.org www.biorxiv.org
    UPF3A and UPF3B are redundant and modular activators of nonsense-mediated mRNA decay in human cells
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  134. www.biorxiv.org www.biorxiv.org
    CROP: A Retromer-PROPPIN complex mediating membrane fission in the endo-lysosomal system
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  135. Apr 2022
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    A genetic program boosts mitochondrial function to power macrophage tissue invasion
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    biorxiv.org/content/10.1101/2021.02.18.431643v1
  137. www.biorxiv.org www.biorxiv.org
    Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores