287 Matching Annotations
  1. Dec 2023
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    YAP antagonizes TEAD-mediated AR signaling and prostate cancer growth
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    1. EMBOpress 01 Dec 2023

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    biorxiv.org/content/10.1101/2022.08.01.502314v1
  3. Nov 2023
  4. www.biorxiv.org www.biorxiv.org
    A bifunctional kinase-phosphatase module integrates mitotic checkpoint and error-correction signalling to ensure mitotic fidelity
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    1. EMBOpress 30 Nov 2023

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    biorxiv.org/content/10.1101/2022.05.22.492960v2
  5. www.biorxiv.org www.biorxiv.org
    Vimentin intermediate filaments organize organellar architecture in response to ER stress
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    1. EMBOpress 28 Nov 2023

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    biorxiv.org/content/10.1101/2022.03.24.485587v1
  6. www.biorxiv.org www.biorxiv.org
    A region-resolved proteomic map of the human brain enabled by high-throughput proteomics
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    1. EMBOpress 21 Nov 2023

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    biorxiv.org/content/10.1101/2023.06.05.543676v1
  7. www.biorxiv.org www.biorxiv.org
    Comprehensive comparison of female germ cell development in vitro and in vivo identifies epigenetic gene regulation crucial for oocyte development and embryonic competence
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    1. EMBOpress 17 Nov 2023

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    biorxiv.org/content/10.1101/2023.02.15.528760v1
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    A network of small RNAs regulates sporulation initiation in C. difficile
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    1. EMBOpress 15 Nov 2023

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    biorxiv.org/content/10.1101/2022.10.17.512509v1
  9. Oct 2023
  10. www.biorxiv.org www.biorxiv.org
    EMBRYO-UTERINE INTERACTION COORDINATES MOUSE EMBRYOGENESIS DURING IMPLANTATION
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    1. EMBOpress 05 Oct 2023

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    biorxiv.org/content/10.1101/2022.06.13.495767v1
  11. Sep 2023
  12. www.biorxiv.org www.biorxiv.org
    Mechanisms and physiological function of daily haemoglobin oxidation rhythms in red blood cells
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    1. EMBOpress 06 Sep 2023

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    biorxiv.org/content/10.1101/2021.10.11.463714v2
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    PTEN deficiency exposes a requirement for an ARF GTPase module in integrin-dependent invasion in ovarian cancer.
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    1. EMBOpress 06 Sep 2023

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    biorxiv.org/content/10.1101/2022.11.29.518198v1
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    A Sterol-PI(4)P exchanger controls the Tel1/ATM axis of the DNA Damage Response
    1
    1. EMBOpress 02 Sep 2023

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    biorxiv.org/content/10.1101/2022.07.13.499867v1
  15. www.biorxiv.org www.biorxiv.org
    Phosphorylation controls spatial and temporal activities of motor-PRC1 complexes to complete mitosis
    1
    1. EMBOpress 01 Sep 2023

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    biorxiv.org/content/10.1101/2023.03.11.531660v1
  16. Aug 2023
  17. www.biorxiv.org www.biorxiv.org
    Randomly incorporated genomic 6mA delays zygotic transcription initiation
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    1. EMBOpress 25 Aug 2023

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    biorxiv.org/content/10.1101/2022.10.27.514014v1
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    Senescent cell death as an aging resistance mechanism in naked mole-rat
    1
    1. EMBOpress 04 Aug 2023

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    biorxiv.org/content/10.1101/2020.07.02.155903v1
  19. www.biorxiv.org www.biorxiv.org
    Synaptotagmin 1 mediates toxicity of botulinum neurotoxin type A
    1
    1. EMBOpress 04 Aug 2023

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    biorxiv.org/content/10.1101/2022.02.28.482398v1
  20. www.biorxiv.org www.biorxiv.org
    Direct observation of coordinated assembly of individual native centromeric nucleosomes
    1
    1. EMBOpress 03 Aug 2023

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    biorxiv.org/content/10.1101/2023.01.20.524981v2
  21. www.biorxiv.org www.biorxiv.org
    Evolutionary transcriptomics reveals longevity mostly driven by polygenic and indirect selection in mammals
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    1. EMBOpress 02 Aug 2023

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    biorxiv.org/content/10.1101/2023.01.09.523139v1
  22. Jul 2023
  23. www.biorxiv.org www.biorxiv.org
    Characterization of the REC114-MEI4-IHO1 complex regulating meiotic DNA double-strand break formation
    1
    1. EMBOpress 29 Jul 2023

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    biorxiv.org/content/10.1101/2023.01.11.523614v1
  24. www.biorxiv.org www.biorxiv.org
    Ribonucleotide synthesis by NME6 fuels mitochondrial gene expression
    1
    1. EMBOpress 28 Jul 2023

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    biorxiv.org/content/10.1101/2022.11.29.518352v1
  25. www.biorxiv.org www.biorxiv.org
    Cohesin-mediated DNA loop extrusion resolves sister chromatids in G2 phase
    1
    1. EMBOpress 15 Jul 2023

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    biorxiv.org/content/10.1101/2023.01.12.523718v1
  26. www.biorxiv.org www.biorxiv.org
    Centrosome amplification fine-tunes tubulin acetylation to differentially control intracellular organization
    1
    1. EMBOpress 13 Jul 2023

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    biorxiv.org/content/10.1101/2022.10.17.512471v1
  27. Jun 2023
  28. www.biorxiv.org www.biorxiv.org
    HNRNPH1 regulates the neuroprotective cold-shock protein RBM3 expression through poison exon exclusion
    1
    1. EMBOpress 29 Jun 2023

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    biorxiv.org/content/10.1101/2022.10.27.514062v1
  29. www.biorxiv.org www.biorxiv.org
    Structural basis of ubiquitin-independent PP1 complex disassembly by p97
    1
    1. EMBOpress 29 Jun 2023

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    biorxiv.org/content/10.1101/2022.06.24.497491v1
  30. www.biorxiv.org www.biorxiv.org
    Multivalent BARD1-nucleosome interactions facilitate H2A ubiquitylation by BRCA1/BARD1
    1
    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.08.09.503292v2
  31. www.biorxiv.org www.biorxiv.org
    PERK Signaling Promotes Mitochondrial Elongation By Remodeling Membrane Phosphatidic Acid
    1
    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.02.23.481593v2
  32. www.biorxiv.org www.biorxiv.org
    Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response
    1
    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.12.21.521356v1
  33. www.biorxiv.org www.biorxiv.org
    Pseudomonas aeruginosa mechanosensing controls cell polarity during twitching by activating two antagonistic response regulators
    1
    1. EMBOpress 24 Jun 2023

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    biorxiv.org/content/10.1101/2022.11.15.516588v1
  34. www.biorxiv.org www.biorxiv.org
    Two distinct mechanisms underlie dosage sensitivity in Pumilio1-associated diseases
    1
    1. EMBOpress 16 Jun 2023

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    biorxiv.org/content/10.1101/2021.03.11.435015v5
  35. www.biorxiv.org www.biorxiv.org
    Stable kinetochore-microtubule attachment requires loop-dependent Ndc80-Ndc80 binding
    1
    1. EMBOpress 15 Jun 2023

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    biorxiv.org/content/10.1101/2022.08.25.505310v1
  36. www.biorxiv.org www.biorxiv.org
    Deterministic and probabilistic fate decisions co-exist in a single retinal lineage
    1
    1. EMBOpress 10 Jun 2023

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    biorxiv.org/content/10.1101/2022.08.11.503564v1
  37. www.biorxiv.org www.biorxiv.org
    Functionally distinct promoter classes initiate transcription via different mechanisms reflected in focused versus dispersed initiation patterns
    1
    1. EMBOpress 10 Jun 2023

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    biorxiv.org/content/10.1101/2022.09.30.509643v2
  38. May 2023
  39. www.biorxiv.org www.biorxiv.org
    Ubx5-Cdc48 assists the protease Wss1 at DNA-protein crosslink sites in yeast
    1
    1. EMBOpress 25 May 2023

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    biorxiv.org/content/10.1101/2022.05.30.493988v1
  40. www.biorxiv.org www.biorxiv.org
    eIF3 mRNA selectivity profiling reveals eIF3k as a cancer-relevant regulator of ribosome content
    1
    1. EMBOpress 25 May 2023

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    biorxiv.org/content/10.1101/2022.08.28.505560v2
  41. www.biorxiv.org www.biorxiv.org
    FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors
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    1. EMBOpress 24 May 2023

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    biorxiv.org/lookup/doi/10.1101/2022.10.12.511867
  42. www.biorxiv.org www.biorxiv.org
    ROR1 plays a critical role in pancreatic tumor-initiating cells with a partial EMT signature.
    1
    1. EMBOpress 19 May 2023

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    biorxiv.org/content/10.1101/2022.07.13.499868v1
  43. www.biorxiv.org www.biorxiv.org
    DASH/Dam1 complex mutants stabilize ploidy by weakening kinetochore-microtubule attachments
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    1. EMBOpress 16 May 2023

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    biorxiv.org/content/10.1101/2022.09.28.509901v1
  44. Apr 2023
  45. www.biorxiv.org www.biorxiv.org
    TOR acts as metabolic gatekeeper for auxin-dependent lateral root initiation in Arabidopsis thaliana
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    1. EMBOpress 28 Apr 2023

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    biorxiv.org/content/10.1101/2022.03.29.486207v2
  46. www.biorxiv.org www.biorxiv.org
    An RNA-binding switch drives ribosome biogenesis and tumorigenesis downstream of RAS oncogene
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    1. EMBOpress 25 Apr 2023

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    biorxiv.org/content/10.1101/2021.12.16.472890v3
  47. www.biorxiv.org www.biorxiv.org
    Cell-extrinsic autophagy in mature adipocytes regulates anti-inflammatory response to intestinal tissue injury through lipid mobilization
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    1. EMBOpress 19 Apr 2023

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    biorxiv.org/content/10.1101/2021.10.25.465200v2
  48. www.biorxiv.org www.biorxiv.org
    Single cell analysis of lymphatic endothelial cell fate specification and differentiation during zebrafish development
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    1. EMBOpress 11 Apr 2023

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    biorxiv.org/content/10.1101/2022.02.10.479999v2
  49. Mar 2023
  50. www.biorxiv.org www.biorxiv.org
    Hda1C limits divergent non-coding transcription and restricts transcription initiation frequency
    1
    1. EMBOpress 15 Mar 2023

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    biorxiv.org/content/10.1101/2021.04.06.438606v1
  51. www.biorxiv.org www.biorxiv.org
    E-Cadherin mediated AMIS localisation
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    1. EMBOpress 15 Mar 2023

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    biorxiv.org/content/10.1101/2021.11.30.470571v5
  52. www.biorxiv.org www.biorxiv.org
    Reconstitution of centrosome positioning by the production of pushing forces in microtubules growing against the actin network.
    1
    1. EMBOpress 15 Mar 2023

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    biorxiv.org/content/10.1101/2022.01.21.476947v1
  53. www.biorxiv.org www.biorxiv.org
    The Grainyhead/LSF transcription factor GRH-1 is rhythmically required for molting
    1
    1. EMBOpress 15 Mar 2023

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    biorxiv.org/content/10.1101/2022.03.01.482504v2
  54. www.biorxiv.org www.biorxiv.org
    Shuffled ATG8 interacting motifs form an ancestral bridge between UFMylation and C53-mediated autophagy
    1
    1. EMBOpress 15 Mar 2023

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    biorxiv.org/content/10.1101/2022.04.26.489478v1
  55. www.biorxiv.org www.biorxiv.org
    An Arrayed Genome-Wide Perturbation Screen Identifies the Ribonucleoprotein hnRNP K As Rate-Limiting for Prion Propagation
    1
    1. EMBOpress 15 Mar 2023

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    biorxiv.org/content/10.1101/2022.03.03.482765v1
  56. www.biorxiv.org www.biorxiv.org
    Uncoupling from transcription protects polyadenylation site cleavage from inhibition by DNA damage
    1
    1. EMBOpress 15 Mar 2023

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    biorxiv.org/content/10.1101/2022.05.26.492040v2
  57. www.biorxiv.org www.biorxiv.org
    The cryo-EM structure of the CENP-A nucleosome in complex with ggKNL2
    1
    1. EMBOpress 15 Mar 2023

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    biorxiv.org/content/10.1101/2022.06.24.497480v1
  58. www.biorxiv.org www.biorxiv.org
    The eukaryotic translation initiation factor eIF4E reprogrammes the splicing machinery anddrives alternative splicing
    1
    1. EMBOpress 15 Mar 2023

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    biorxiv.org/content/10.1101/2021.12.07.471666v4
  59. www.biorxiv.org www.biorxiv.org
    Structure and mechanism of a novel cytomegaloviral DCAF mediating interferon antagonism
    1
    1. EMBOpress 07 Mar 2023

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    The Proxitome of Arabidopsis Processing Bodies Reveals a Condensate-Membrane Interface Instructing Actin-Driven Directional Growth
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  61. Feb 2023
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    TORC1 phosphorylates and inhibits the ribosome preservation factor Stm1 to activate dormant ribosomes
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    MitoStores: Chaperone-controlled protein granules store mitochondrial precursors in the cytosol
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    Retromer oligomerization drives SNX-BAR coat assembly and membrane constriction
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    Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis
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    The blood vasculature instructs lymphatics patterning in a SOX7-dependent manner
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    TSC2 regulates tumor susceptibility to TRAIL-mediated T cell killing by orchestrating mTOR signaling
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    Transient ribosome slowdown at the decoding step triggers mRNA degradation independent of Znf598 in zebrafish
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    A molecular mechanism by which amyloid-β induces transcriptional inactivation of CREB in Alzheimer's Disease
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    Plasma membrane topography governs the three-dimensional dynamic localization of IgM B cell receptor clusters
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    Condensin pinches a short negatively supercoiledDNA loop during each round of ATP usage
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  73. Dec 2022
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    When Yeast Cells Change their Mind: Cell Cycle 'Start' is Reversible under Starvation
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    Structural and biochemical basis of FANCI-FANCD2 interdependent ubiquitination
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    Cue-specific remodeling of the neuronal transcriptome through intron retention programs
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    The E3 ligase RNF115 regulates phagosome maturation and host response to bacterial infection
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    A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
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    m6A is required for resolving progenitor identity during planarian stem cell differentiation
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    Structure and functional mapping of the KRAB-KAP1 repressor complex
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    Temporal and sequential transcriptional dynamics define lineage shifts in corticogenesis
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    An ERAD-independent role for rhomboid pseudoprotease Dfm1 in mediating sphingolipid homeostasis
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    RNA-mediated nucleosome depletion is required for elimination of transposon-derived DNA.
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    Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity
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    Cellular stress in brain organoids is limited to a distinct and bioinformatically removable subpopulation.
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    HEAT SHOCK FACTOR BINDING PROTEIN limits meiotic crossovers by repressing HEI10 transcription
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    TSG101 Associates with PARP1 and is Essential for PARylation and DNA Damage-induced NF-κB Activation
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    A conserved signaling pathway activates bacterial CBASS immune signaling in response to DNA damage
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    CRYPTOCHROME suppresses the circadian proteome and promotes protein homeostasis
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    Naked mole-rat hematopoietic stem and progenitors are highly quiescent with an inherent myeloid bias
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    Regulation of mitochondrial proteostasis by the proton gradient
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    Heterotypic Assembly Mechanism Regulates CHIP E3 Ligase Activity
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    Mitotic checkpoint gene expression is tuned by coding sequences
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    Nuclear Pore Complex Acetylation Regulates mRNA Export and Cell Cycle Commitment in Budding Yeast
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    Cellular toxicity of iHAP1 and DT-061 does not occur through PP2A-B56 targeting
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    Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms
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    Cooperative Amyloid Fibre Binding and Disassembly by the Hsp70 disaggregase
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    Precise control of microtubule disassembly in living cells
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    Varicella-Zoster Virus ORF9 Is an Antagonist of the DNA Sensor cGAS
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    Self-ubiquitination of a pathogen type-III effector traps and blocks the autophagy machinery to promote disease
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    A temporally controlled sequence of X-chromosomeinactivation and reactivation defines female mouse in vitro germ cells with meiotic potential
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  103. Jun 2022
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    A RIF1 and KAP1-based, double-bookmarking system generates a toggle switch that stabilises the identities of the active and inactive X chromosomes during random X inactivation in mouse
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    Centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly
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    Structural basis for feedforward control in the PINK1/parkin pathway
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    UPF3A and UPF3B are redundant and modular activators of nonsense-mediated mRNA decay in human cells
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    CROP: A Retromer-PROPPIN complex mediating membrane fission in the endo-lysosomal system
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    A genetic program boosts mitochondrial function to power macrophage tissue invasion
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    Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores
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    REDUCED ER-MITOCHONDRIA CONNECTIVITY PROMOTES NEUROBLASTOMA MULTIDRUG RESISTANCE
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    Autophagy suppression by TORC1 maintains epithelial plasma membrane integrity and inhibits syncytium formation
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    1. EMBOpress 23 Mar 2022

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      PeerReviewed EMBOPress The EMBO Journal cell biology
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    biorxiv.org/content/10.1101/2021.08.05.455228v1
  117. www.biorxiv.org www.biorxiv.org
    Specialization of actin isoforms derived from the loss of key interactions with regulatory factors
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    1. EMBOpress 22 Mar 2022

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      PeerReviewed EMBOPress The EMBO Journal cell biology
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    biorxiv.org/content/10.1101/2021.02.09.430555v1
  118. www.biorxiv.org www.biorxiv.org
    Epigenetic Inheritance is Gated by Naive Pluripotency and Dppa2
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    1. EMBOpress 22 Mar 2022

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      PeerReviewed EMBOPress The EMBO Journal genetics
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    biorxiv.org/content/10.1101/2021.05.11.443595v1
  119. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2020.08.18.255810
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    1. EMBOpress 19 Mar 2022

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      PeerReviewed EMBOPress The EMBO Journal immunology
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    biorxiv.org/content/10.1101/2020.08.18.255810v2
  120. www.biorxiv.org www.biorxiv.org
    Rewiring phospholipid biosynthesis reveals robustness in membrane homeostasis and uncovers lipid regulatory players.
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    1. EMBOpress 12 Mar 2022

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    biorxiv.org/content/10.1101/2021.07.20.453065v1
  121. www.biorxiv.org www.biorxiv.org
    Heterotypic Aβ interactions facilitate amyloid assembly and modify amyloid structure
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    1. EMBOpress 11 Mar 2022

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      PeerReviewed EMBOPress The EMBO Journal neuroscience
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    biorxiv.org/content/10.1101/2021.04.28.441786v1
  122. www.biorxiv.org www.biorxiv.org
    The nucleoporin Nup50 activates the Ran guanyl-nucleotide exchange factor RCC1 to promote mitotic NPC assembly
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    1. EMBOpress 10 Mar 2022

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    biorxiv.org/content/10.1101/2021.03.31.437874v1
  123. www.biorxiv.org www.biorxiv.org
    Balancing the length of distal tip is key for stability and signalling function of primary cilia
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    1. EMBOpress 09 Mar 2022

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    biorxiv.org/content/10.1101/2021.06.04.447095v1
  124. www.biorxiv.org www.biorxiv.org
    Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation
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    1. EMBOpress 09 Mar 2022

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      PeerReviewed EMBOPress The EMBO Journal biochemistry
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    biorxiv.org/content/10.1101/2021.04.30.442163v1
  125. www.biorxiv.org www.biorxiv.org
    Versatile genetic toolbox for Prevotella copri enables studying polysaccharide utilization systems
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    1. EMBOpress 09 Mar 2022

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      PeerReviewed EMBOPress The EMBO Journal microbiology
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    biorxiv.org/content/10.1101/2021.03.19.436125v1
  126. Feb 2022
  127. www.biorxiv.org www.biorxiv.org
    Low membrane fluidity triggers lipid phase separation and protein segregation in vivo
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    1. EMBOpress 15 Feb 2022

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    biorxiv.org/content/10.1101/852160v2
  128. www.biorxiv.org www.biorxiv.org
    CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawal
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    1. EMBOpress 11 Feb 2022

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      PeerReviewed EMBOPress The EMBO Journal cancer biology
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    biorxiv.org/content/10.1101/2021.02.03.428245v1
  129. www.biorxiv.org www.biorxiv.org
    Molecular species selectivity of lipid transport creates a mitochondrial sink for di-unsaturated phospholipids
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    1. EMBOpress 03 Feb 2022

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      PeerReviewed EMBOPress The EMBO Journal biochemistry
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    biorxiv.org/content/10.1101/2020.06.08.140129v1
  130. www.biorxiv.org www.biorxiv.org
    Ontogeny and function of the circadian clock in intestinal organoids
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      PeerReviewed EMBOPress The EMBO Journal molecular biology
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    biorxiv.org/content/10.1101/2020.04.22.053223v1
  131. Jan 2022
  132. www.biorxiv.org www.biorxiv.org
    Nascent polypeptide within the exit tunnel ensures continuous translation elongation by stabilizing the translating ribosome
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