79 Matching Annotations
  1. May 2025
  2. www.biorxiv.org www.biorxiv.org
    Shared requirement for MYC upstream super-enhancer in tissue regeneration and cancer
    1
    1. EMBOpress 20 May 2025

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    biorxiv.org/content/10.1101/2022.11.04.515076v2
  3. www.biorxiv.org www.biorxiv.org
    Mitochondrial Signatures Shape Phenotype Switching and Apoptosis in Response to PLK1 and RSK Inhibitors in Melanoma
    1
    1. EMBOpress 20 May 2025

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    biorxiv.org/content/10.1101/2024.06.14.599035v1
  4. www.biorxiv.org www.biorxiv.org
    Transcription Factor EB (TFEB) activity increases resistance of TNBC stem cells to metabolic stress
    1
    1. EMBOpress 20 May 2025

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    biorxiv.org/content/10.1101/2023.05.30.542913v1
  5. www.biorxiv.org www.biorxiv.org
    Loss-of-function cancer-associated mutations in the EIF4G2 non-canonical translation initiation factor
    1
    1. EMBOpress 20 May 2025

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    biorxiv.org/content/10.1101/2023.08.22.554280v2
  6. Dec 2024
  7. www.biorxiv.org www.biorxiv.org
    A complete digital karyotype of the B-cell leukemia REH cell line resolved by long-read sequencing
    1
    1. EMBOpress 12 Dec 2024

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    biorxiv.org/content/10.1101/2023.03.08.531483v1
  8. Oct 2024
  9. www.biorxiv.org www.biorxiv.org
    Reprogramming of breast tumor-associated macrophages with modulation of arginine metabolism
    1
    1. EMBOpress 03 Oct 2024

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    biorxiv.org/content/10.1101/2023.08.22.554238v1
  10. Sep 2024
  11. www.biorxiv.org www.biorxiv.org
    Proteomic analysis reveals microvesicles containing NAMPT as mediators of radiation resistance in glioma
    1
    1. EMBOpress 11 Sep 2024

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    biorxiv.org/lookup/doi/10.1101/2022.03.23.485479
  12. Apr 2024
  13. www.biorxiv.org www.biorxiv.org
    Integrative DNA methylation analysis of pediatric brain tumors reveals tumor type-specific developmental trajectories and epigenetic signatures of malignancy
    1
    1. EMBOpress 27 Apr 2024

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    biorxiv.org/content/10.1101/2022.03.14.483566v2
  14. Feb 2024
  15. www.biorxiv.org www.biorxiv.org
    CRISPR-Cas9-mediated genome engineering exaggerates genomic deletion at 10q23.31 including the PTEN gene locus mimicking cancer profiles
    1
    1. EMBOpress 03 Feb 2024

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    biorxiv.org/content/10.1101/2023.04.05.535680v1
  16. Jan 2024
  17. www.biorxiv.org www.biorxiv.org
    Proteomic-based stratification of intermediate-risk prostate cancer patients
    1
    1. EMBOpress 26 Jan 2024

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    biorxiv.org/content/10.1101/2023.03.03.530910v1
  18. docdrop.org docdrop.org
    Video: Let Food Be Thy Medicine: EAT THIS To Heal The Body & STARVE CANCER! | Dr. William Li (DocDrop)
    1
    1. stopresetgo 25 Jan 2024

      for - healthy eating - Dr. William Li - nutrition - healthy food - inflammation - angiogenesis

      summary - A good interview about human health and healthy diet. William Li begins by talking about angiogenesis as a key aspect of human health - and how pathology of angiogenesis is at the root of many major diseases. - The interviewer then asks Dr. Li about the connection between another keystone disease, and angiogenesis. - Dr. Li then describes some healthy foods and good dietary practices including extra virgin olive oil.

      adjacency - between - angiogenesis - inflammation - Micheal Levine's work - evolutionary biology - adjacency statement - they all seem related, as evolutionary biology has created legacy subsystems within the human body

      adjacency - Michael Levine - angiogenesis - inflammation angiogenesis inflammation adjacency - cancer - inflammation - angiogenesis adjacency - food - angiogenesis - cancer adjacency - michael levine - evolutionary biology - angiogenesis
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    docdrop.org/video/cNPV_5stNLo/
  19. Dec 2023
  20. www.biorxiv.org www.biorxiv.org
    TUMOR ENDOTHELIAL CELL AUTOPHAGY IS A KEY VASCULAR-IMMUNE CHECKPOINT IN MELANOMA
    1
    1. EMBOpress 16 Dec 2023

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    biorxiv.org/content/10.1101/2023.04.21.537799v2
  21. www.biorxiv.org www.biorxiv.org
    Paralog dispensability shapes homozygous deletion patterns in tumor genomes
    1
    1. EMBOpress 13 Dec 2023

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    biorxiv.org/content/10.1101/2022.06.20.496722v3
  22. www.biorxiv.org www.biorxiv.org
    Downregulation of stromal syntenin sustains AML development
    1
    1. EMBOpress 12 Dec 2023

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    biorxiv.org/content/10.1101/2023.02.15.527799v1
  23. www.biorxiv.org www.biorxiv.org
    NRF2 connects Src tyrosine kinase to ferroptosis resistance in glioblastoma
    1
    1. EMBOpress 09 Dec 2023

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    biorxiv.org/content/10.1101/2023.05.08.539792v1
  24. www.biorxiv.org www.biorxiv.org
    YAP antagonizes TEAD-mediated AR signaling and prostate cancer growth
    1
    1. EMBOpress 01 Dec 2023

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    biorxiv.org/content/10.1101/2022.08.01.502314v1
  25. Sep 2023
  26. www.biorxiv.org www.biorxiv.org
    PTEN deficiency exposes a requirement for an ARF GTPase module in integrin-dependent invasion in ovarian cancer.
    1
    1. EMBOpress 06 Sep 2023

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    biorxiv.org/content/10.1101/2022.11.29.518198v1
  27. www.biorxiv.org www.biorxiv.org
    Discovery of oncogenic ROS1 missense mutations with sensitivity to tyrosine kinase inhibitors
    1
    1. EMBOpress 02 Sep 2023

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    biorxiv.org/content/10.1101/2022.12.27.521482v1
  28. Aug 2023
  29. www.biorxiv.org www.biorxiv.org
    NLRP3 controls ATM activation in response to DNA damage.
    1
    1. EMBOpress 26 Aug 2023

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    biorxiv.org/content/10.1101/2020.05.12.087015v1
  30. www.biorxiv.org www.biorxiv.org
    ATR inhibition augments the efficacy of lurbinectedin in small cell lung cancer
    1
    1. EMBOpress 02 Aug 2023

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    biorxiv.org/content/10.1101/2022.12.16.520783v1
  31. Jun 2023
  32. www.biorxiv.org www.biorxiv.org
    Highly multiplexed quantitative phosphosite assay for biology and preclinical studies
    1
    1. EMBOpress 10 Jun 2023

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    biorxiv.org/content/10.1101/2020.12.08.415281v1
  33. May 2023
  34. www.biorxiv.org www.biorxiv.org
    RAS and PP2A activities converge on epigenetic gene regulation
    1
    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.05.11.491459v1
  35. www.biorxiv.org www.biorxiv.org
    ROR1 plays a critical role in pancreatic tumor-initiating cells with a partial EMT signature.
    1
    1. EMBOpress 19 May 2023

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    biorxiv.org/content/10.1101/2022.07.13.499868v1
  36. Apr 2023
  37. www.biorxiv.org www.biorxiv.org
    β-catenin activity induces an RNA biosynthesis program promoting therapy resistance in T Acute Lymphoblastic Leukemia
    1
    1. EMBOpress 27 Apr 2023

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    biorxiv.org/content/10.1101/2022.07.07.499249v1
  38. www.biorxiv.org www.biorxiv.org
    An RNA-binding switch drives ribosome biogenesis and tumorigenesis downstream of RAS oncogene
    1
    1. EMBOpress 25 Apr 2023

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    biorxiv.org/content/10.1101/2021.12.16.472890v3
  39. Mar 2023
  40. www.biorxiv.org www.biorxiv.org
    Non-canonical miRNA-RNA base-pairing impedes tumor suppressor activity of miR-16
    1
    1. EMBOpress 15 Mar 2023

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    biorxiv.org/content/10.1101/2021.11.30.470499v1
  41. www.biorxiv.org www.biorxiv.org
    Blockade of pro-fibrotic response mediated by the miR-143/-145 cluster prevents targeted therapy-induced phenotypic plasticity and delays resistance in melanoma
    1
    1. EMBOpress 15 Mar 2023

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    biorxiv.org/content/10.1101/2021.07.02.450838v1
  42. www.biorxiv.org www.biorxiv.org
    The eukaryotic translation initiation factor eIF4E reprogrammes the splicing machinery anddrives alternative splicing
    1
    1. EMBOpress 15 Mar 2023

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    biorxiv.org/content/10.1101/2021.12.07.471666v4
  43. Feb 2023
  44. www.biorxiv.org www.biorxiv.org
    The mechanosensitive TRPV2 calcium channel controls melanoma invasiveness and metastatic potential.
    1
    1. EMBOpress 28 Feb 2023

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    biorxiv.org/content/10.1101/2021.10.22.465391v1
  45. www.biorxiv.org www.biorxiv.org
    TSC2 regulates tumor susceptibility to TRAIL-mediated T cell killing by orchestrating mTOR signaling
    1
    1. EMBOpress 15 Feb 2023

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    biorxiv.org/content/10.1101/2022.05.09.491124v1
  46. Jan 2023
  47. www.biorxiv.org www.biorxiv.org
    Pan-Cancer landscape of protein activities identifies drivers of signalling dysregulation and patient survival
    1
    1. EMBOpress 28 Jan 2023

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    biorxiv.org/content/10.1101/2021.06.09.447741v1
  48. Nov 2022
  49. www.biorxiv.org www.biorxiv.org
    Heterogeneity of the Cancer Cell Line Metabolic Landscape
    1
    1. EMBOpress 21 Nov 2022

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    biorxiv.org/content/10.1101/2021.08.19.456093v1
  50. www.biorxiv.org www.biorxiv.org
    Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes
    1
    1. EMBOpress 21 Nov 2022

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    biorxiv.org/content/10.1101/2022.01.03.474504v1
  51. www.biorxiv.org www.biorxiv.org
    Longitudinal monitoring of disease burden and response using ctDNA from dried blood spots in xenograft models
    1
    1. EMBOpress 21 Nov 2022

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    biorxiv.org/content/10.1101/2022.01.15.476442v1
  52. www.biorxiv.org www.biorxiv.org
    THEM6-mediated lipid remodelling sustains stress resistance in cancer
    1
    1. EMBOpress 21 Nov 2022

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    biorxiv.org/content/10.1101/2021.04.04.438378v1
  53. Jun 2022
  54. www.biorxiv.org www.biorxiv.org
    Genetic and compound screens uncover factors modulating cancer cell response to indisulam
    1
    1. EMBOpress 02 Jun 2022

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    biorxiv.org/content/10.1101/2021.12.20.473451v1
  55. Apr 2022
  56. www.biorxiv.org www.biorxiv.org
    Polycomb Group Ring Finger Protein 6 suppresses Myc-induced lymphomagenesis
    1
    1. EMBOpress 23 Apr 2022

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    biorxiv.org/content/10.1101/2021.12.02.470967v1
  57. www.biorxiv.org www.biorxiv.org
    TET2-mediated epigenetic reprogramming of breast cancer cells impairs lysosome biogenesis
    1
    1. EMBOpress 22 Apr 2022

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    biorxiv.org/content/10.1101/2021.10.27.466063v1
  58. Mar 2022
  59. www.biorxiv.org www.biorxiv.org
    REDUCED ER-MITOCHONDRIA CONNECTIVITY PROMOTES NEUROBLASTOMA MULTIDRUG RESISTANCE
    1
    1. EMBOpress 29 Mar 2022

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    biorxiv.org/content/10.1101/2021.03.01.433120v1
  60. Feb 2022
  61. www.biorxiv.org www.biorxiv.org
    A census of cell types and paracrine interactions in colorectal cancer
    1
    1. EMBOpress 25 Feb 2022

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    biorxiv.org/content/10.1101/2020.01.10.901579v3
  62. www.biorxiv.org www.biorxiv.org
    CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawal
    1
    1. EMBOpress 11 Feb 2022

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    biorxiv.org/content/10.1101/2021.02.03.428245v1
  63. www.biorxiv.org www.biorxiv.org
    Cell Communication Network factor 4 promotes tumor-induced immunosuppression in melanoma
    1
    1. EMBOpress 09 Feb 2022

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    biorxiv.org/content/10.1101/2021.02.23.432584v3
  64. www.biorxiv.org www.biorxiv.org
    Nucleotide Biosynthesis Links Glutathione Metabolism to Ferroptosis Sensitivity
    1
    1. EMBOpress 03 Feb 2022

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    biorxiv.org/content/10.1101/2021.07.14.452394v1
  65. Jan 2022
  66. www.biorxiv.org www.biorxiv.org
    The Sec61 translocon is a therapeutic vulnerability in Multiple Myeloma
    1
    1. EMBOpress 28 Jan 2022

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    biorxiv.org/content/10.1101/2021.09.05.459026v1
  67. Dec 2021
  68. www.nature.com www.nature.com
    Replicating scientific results is tough — but essential
    1
    1. lucyparfitt16 15 Dec 2021

      Replicating scientific results is tough—But essential. (2021). Nature, 600(7889), 359–360. https://doi.org/10.1038/d41586-021-03736-4

      is:article lang:en science replication research cancer biology scientific journal Reproducibility Project experimental treatment bias time consuming detail open science scientific method methodology data peer review funding publishing investment progress
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    nature.com/articles/d41586-021-03736-4
  69. Nov 2021
  70. www.biorxiv.org www.biorxiv.org
    The unfolded protein response links tumor aneuploidy to local immune dysregulation
    1
    1. EMBOpress 24 Nov 2021

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    biorxiv.org/content/10.1101/2020.11.10.377358v1
  71. Oct 2021
  72. www.biorxiv.org www.biorxiv.org
    RASSF1C oncogene elicits amoeboid invasion, cancer stemness and invasive EVs via a novel SRC/Rho axis
    1
    1. EMBOpress 26 Oct 2021

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    biorxiv.org/lookup/doi/10.1101/2021.01.05.425393
  73. Jul 2021
  74. www.biorxiv.org www.biorxiv.org
    Primary platinum resistance and immune exclusion in ovarian carcinomas with high expression of the homologous recombination mediator RAD51
    1
    1. EMBOpress 17 Jul 2021

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    biorxiv.org/content/10.1101/2020.06.09.137612v1
  75. www.biorxiv.org www.biorxiv.org
    Targeting the SHP2 phosphatase promotes vascular damage and inhibition of tumor growth
    1
    1. EMBOpress 16 Jul 2021

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    biorxiv.org/content/10.1101/2020.10.06.327882v1
  76. Jun 2021
  77. www.biorxiv.org www.biorxiv.org
    Aneuploid cells activate NF-κB to promote their immune clearance by NK cells
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    1. EMBOpress 30 Jun 2021

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    biorxiv.org/content/10.1101/2020.06.25.172239v1
  78. www.biorxiv.org www.biorxiv.org
    Pancreatic Cancer Intrinsic PI3Kα Activity accelerates Metastasis and rewires Macrophage Component
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    1. EMBOpress 08 Jun 2021

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    biorxiv.org/content/10.1101/2020.09.23.307884v1
  79. Apr 2021
  80. www.biorxiv.org www.biorxiv.org
    Identifying Modules of Cooperating Cancer Drivers
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    biorxiv.org/content/10.1101/2020.06.29.168229v1
  81. www.biorxiv.org www.biorxiv.org
    Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor
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    biorxiv.org/content/10.1101/2020.01.31.929372v1
  82. www.biorxiv.org www.biorxiv.org
    WNT inhibition creates a BRCA-like state in Wnt-addicted cancer
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    1. EMBOpress 02 Apr 2021

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    biorxiv.org/content/10.1101/2020.06.17.157024v1
  83. Feb 2021
  84. www.biorxiv.org www.biorxiv.org
    A FIJI Macro for quantifying pattern in extracellular matrix
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    1. EMBOpress 25 Feb 2021

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    biorxiv.org/content/10.1101/867507v4
  85. www.biorxiv.org www.biorxiv.org
    IMiDs induce FAM83F degradation via an interaction with CK1α to attenuate Wnt signalling
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    1. EMBOpress 25 Feb 2021

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    biorxiv.org/content/10.1101/2020.05.25.114660v1
  86. www.biorxiv.org www.biorxiv.org
    Helicobacter pylori accelerates KRAS-dependent gastric dysplasia
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    1. EMBOpress 25 Feb 2021

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    biorxiv.org/content/10.1101/2020.10.06.328518v1
  87. www.biorxiv.org www.biorxiv.org
    LSD1 inhibitors induce neuronal differentiation of Merkel cell carcinoma by disrupting the LSD1-CoREST complex and activating TGFβ signaling
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    1. EMBOpress 25 Feb 2021

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    biorxiv.org/content/10.1101/2020.04.14.041657v1
  88. www.biorxiv.org www.biorxiv.org
    The Mutational Landscape of the SCAN-B Real-World Primary Breast Cancer Transcriptome
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    1. EMBOpress 25 Feb 2021

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    biorxiv.org/content/10.1101/2020.01.30.926733v1
  89. Oct 2020
  90. www.biorxiv.org www.biorxiv.org
    DDX5 targets tissue-specific RNAs to promote intestine tumorigenesis
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    biorxiv.org/content/10.1101/2020.03.25.006668v1
  91. www.biorxiv.org www.biorxiv.org
    Reprogrammed mRNA translation drives metabolic response to therapeutic targeting of ribosome biogenesis
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    biorxiv.org/content/10.1101/847723v3
  92. www.biorxiv.org www.biorxiv.org
    The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism
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    biorxiv.org/content/10.1101/855361v1
  93. Jul 2020
  94. www.biorxiv.org www.biorxiv.org
    Small molecule inhibitors and a kinase-dead expressing mouse model demonstrate that the kinase activity of Chk1 is essential for mouse embryos and cancer cells
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    1. EMBOpress 15 Jul 2020

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    biorxiv.org/content/10.1101/2020.01.21.913467v1
  95. www.biorxiv.org www.biorxiv.org
    STAT3-dependent systems-level analysis reveals PDK4 as an independent predictor of biochemical recurrence in prostate cancer
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    biorxiv.org/content/10.1101/770701v1
  96. www.biorxiv.org www.biorxiv.org
    Stromal ISLR promotes intestinal regeneration and cancer by suppressing epithelial Hippo signaling
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    biorxiv.org/content/10.1101/740472v1
  97. www.biorxiv.org www.biorxiv.org
    An early Myc-dependent transcriptional program underlies enhanced macromolecular biosynthesis and cell growth during B-cell activation
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    biorxiv.org/content/10.1101/561464v2
  98. www.biorxiv.org www.biorxiv.org
    Hippo Pathway Deregulation Drives Tissue Stiffness and Cancer Stem-like Cells in Lung Adenocarcinoma
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    biorxiv.org/content/10.1101/390849v1
  99. www.biorxiv.org www.biorxiv.org
    EZH2 co-opts gain-of-function p53 mutants to promote cancer growth and metastasis
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    biorxiv.org/content/10.1101/298737v1
  100. Jun 2020
  101. www.biorxiv.org www.biorxiv.org
    Ubiquitin and SUMO conjugation as biomarkers of Acute Myeloid Leukemias response to chemotherapies
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    biorxiv.org/content/10.1101/825182v1
  102. www.biorxiv.org www.biorxiv.org
    The USP28-{triangleup}Np63 axis is a vulnerability of squamous tumours
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    biorxiv.org/content/10.1101/683508v1
  103. www.biorxiv.org www.biorxiv.org
    Preservation of stemness in high-grade serous ovarian cancer organoids requires low Wnt environment
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    biorxiv.org/content/10.1101/741397v1
  104. Sep 2019
  105. www.biorxiv.org www.biorxiv.org
    Tumor-Intrinsic Response to IFNgamma Shapes the Tumor Microenvironment and Anti-PD-1 Response in NSCLC
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    biorxiv.org/content/10.1101/531236v1
  106. www.biorxiv.org www.biorxiv.org
    Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy
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    biorxiv.org/content/10.1101/284240v2
  107. www.biorxiv.org www.biorxiv.org
    Fibroblasts from metastatic sites induce broad-spectrum drug desensitization via modulation of mitochondrial priming
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    biorxiv.org/content/10.1101/197376v1
  108. www.biorxiv.org www.biorxiv.org
    Whole chromosome loss in tetraploid cells confers tumorigenic potential in a mouse allograft model
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    biorxiv.org/content/10.1101/172668v1
  109. www.biorxiv.org www.biorxiv.org
    FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.
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    biorxiv.org/content/10.1101/365460v1
  110. www.biorxiv.org www.biorxiv.org
    Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib
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    biorxiv.org/content/10.1101/202770v1
  111. www.biorxiv.org www.biorxiv.org
    Small interfering RNAs based on huntingtin trinucleotide repeats are highly toxic to cancer cells
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    biorxiv.org/content/10.1101/247429v1
  112. www.biorxiv.org www.biorxiv.org
    Resolving Drug Effects In Patient-Derived Cancer Cells Links Organoid Responses To Genome Alterations
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    biorxiv.org/content/10.1101/124446v1