60 Matching Annotations
  1. Jul 2021
  2. Jun 2021
  3. May 2021
    1. Braud, M., Gaboriaud, A., Ferry, T., Mardi, W. E., Silva, L. D., Lemouzy, M., Guttierrez, J., Petit, S., Szabelska, A., & IJzerman, H. (2021). COVID-19-related conspiracy beliefs and their relationship with perceived stress and pre-existing conspiracy beliefs in a Prolific Academic sample: A replication and extension of Georgiou et al. (2020). PsyArXiv. https://doi.org/10.31234/osf.io/t62s7

  4. Apr 2021
  5. Mar 2021
  6. Feb 2021
  7. Dec 2020
    1. All replication in R6K relies on the two essential components of a minimal replicon, the γ ori, and its cognate Rep, π protein, encoded by the pir gene
    1. Corker, K. S., Arnal, J., Bonfiglio, D. B. V., Curran, P. G., Chartier, C. R., Chopik, W. J., Guadagno, R., Kimbrough, A., Schmidt, K., & Wiggins, B. J. (2020). Many Labs 5: Registered Replication of Albarracín et al. (2008), Experiment 7. PsyArXiv. https://doi.org/10.31234/osf.io/qzspr

  8. Nov 2020
    1. Replication begins

      Rolling circle replication overview

      Replication begins when the Rep protein, which is encoded on the plasmid (ORF A), recognizes a specific site on the plasmid (double-strand origin, or DSO) and catalyzes the nicking of one DNA strand. The Rep protein remains bound to the 5′ phosphate after the nicking action. The newly released 3′ hydroxyl on the opposite end serves as a primer for DNA synthesis. The host DNA polymerase uses the unnicked circular strand as a template, so that a single replication fork moves around a plasmid until it regenerates the DSO. A second copy of Rep protein catalyzes the cleavage of the newly formed DSO, effectively releasing a single stranded copy of the plasmid. In the absence of Rep, the replication fork continues to move around the template, forming a single stranded concatemer. The single strand origin (SSO), a non-coding element that forms extensive secondary structure, is required for synthesis of the lagging strand. SSO sequences vary considerably among different RCR plasmids, but are extremely important for robust replication of the plasmid in the cell [10]. Here we describe the engineering of the pWV01 RCR origin to create pBAV1K-T5, a very broad-host range expression vector.

  9. Oct 2020
  10. Sep 2020
  11. Aug 2020
    1. Luban, J., Sattler, R., Mühlberger, E., Graci, J. D., Cao, L., Weetall, M., Trotta, C., Colacino, J. M., Bavari, S., Strambio-De-Castillia, C., Suder, E. L., Wang, Y., Soloveva, V., Cintron-Lue, K., Naryshkin, N. A., Pykett, M., Welch, E. M., O’Keefe, K., Kong, R., … Peltz, S. (2020). The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines. BioRxiv, 2020.08.05.238394. https://doi.org/10.1101/2020.08.05.238394

  12. Jul 2020
    1. Listens to changes in a PostgreSQL Database and broadcasts them over WebSocket. It works like this:the Phoenix server listens to PostgreSQL's replication functionality (using Postgres' logical decoding).it converts the byte stream into JSON.it then broadcasts over WebSocket.
  13. Jun 2020
  14. May 2020
  15. Apr 2020
  16. Feb 2020
    1. 0.506 (0.532)

      can we find any measures of dispersion here?

    2. For the 12 studies with an original p < 0.005, 10 (83%) replicated. For the 12 studies with an original p > 0.005, only 1 (8%) replicated. Further work is needed to test if prediction markets outperform predictions based only on the initial p-value, to test if the market also aggregates other information important for reproducibility.

      p values may capture all the information?

  17. Jan 2020
  18. Dec 2019
    1. "The replication crisis, if nothing else, has shown that productivity is not intrinsically valuable. Much of what psychology has produced has been shown, empirically, to be a waste of time, effort, and money. As Gibson put it: our gains are puny, our science ill-founded. As a subject, it is hard to see what it has to lose from a period of theoretical confrontation. The ultimate response to the replication crisis will determine whether this bout is postponed or not."

  19. Jul 2019
  20. Jun 2016
    1. etter writing continued as a medium for theinformal exchange of information and for requesting fellowscientists to replicate experiments (Manten, 1980, p. 8).

      replication happened outside of journals, via letter writing

  21. Mar 2016
    1. Schmidt, S. (2009). Shall we really do it again? The powerful concept of replication is neglected in thesocial sciences.Review of General Psychology, 13(2), 90–100.
    2. Evanschitzky, H., Baumgarth, C., Hubbard, R., & Armstrong, J. S. (2007). Replication research’s disturbingtrend.Journal of Business Research, 60(4), 411–415. doi

      replication research

  22. Jan 2015
    1. Teachers can save digital content to the built-in storage and up to 50 students at a time can connect to the Access Point to download or access documents, videos, or other files on their own devices even if there’s no internet signal.

      CouchDB replication anyone?

  23. Oct 2013