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Gilbert, P. B., Montefiori, D. C., McDermott, A., Fong, Y., Benkeser, D. C., Deng, W., Zhou, H., Houchens, C. R., Martins, K., Jayashankar, L., Castellino, F., Flach, B., Lin, B. C., O’Connell, S., McDanal, C., Eaton, A., Sarzotti-Kelsoe, M., Lu, Y., Yu, C., … Teams, U. S. G. (USG)/CoVPN B. (2021). Immune Correlates Analysis of the mRNA-1273 COVID-19 Vaccine Efficacy Trial. MedRxiv, 2021.08.09.21261290. https://doi.org/10.1101/2021.08.09.21261290
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Gutman, R. (2021, October 28). Is Moderna Really Better Than Pfizer—Or Is It Just a Higher Dose? The Atlantic. https://www.theatlantic.com/health/archive/2021/10/pfizer-moderna-dose-which-vaccine-best/620501/
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Sadoff, J., Gars, M. L., Cardenas, V., Shukarev, G., Vaissiere, N., Heerwegh, D., Truyers, C., Groot, A. M. de, Scheper, G., Hendriks, J., Ruiz-Guinazu, J., Struyf, F., Hoof, J. V., Douoguih, M., & Schuitemaker, H. (2021). Durability of antibody responses elicited by a single dose of Ad26.COV2.S and substantial increase following late boosting (p. 2021.08.25.21262569). https://doi.org/10.1101/2021.08.25.21262569
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Bloom, J., & Cobey, S. (2021, December 12). Opinion | A Scientist’s Guide to Understanding Omicron. The New York Times. https://www.nytimes.com/2021/12/12/opinion/covid-omicron-data.html
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Gebre, M. S., Rauch, S., Roth, N., Yu, J., Chandrashekar, A., Mercado, N. B., He, X., Liu, J., McMahan, K., Martinot, A., Martinez, D. R., Giffin, T., Hope, D., Patel, S., Sellers, D., Sanborn, O., Barrett, J., Liu, X., Cole, A. C., … Barouch, D. H. (2021). Optimization of Non-Coding Regions for a Non-Modified mRNA COVID-19 Vaccine. Nature, 1–8. https://doi.org/10.1038/s41586-021-04231-6
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Anthes, E. (2021, August 19). What to Know About Boosters if You Got the Johnson & Johnson Vaccine. The New York Times. https://www.nytimes.com/2021/08/19/health/coronavirus-johnson-vaccine-booster.html
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Iketani, S., Liu, L., Guo, Y., Liu, L., Huang, Y., Wang, M., Luo, Y., Yu, J., Yin, M. T., Sobieszczyk, M. E., Huang, Y., Wang, H. H., Sheng, Z., & Ho, D. D. (2022). Antibody Evasion Properties of SARS-CoV-2 Omicron Sublineages (p. 2022.02.07.479306). bioRxiv. https://doi.org/10.1101/2022.02.07.479306
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Zimmer, C. (2021, September 21). An extra J. & J. shot substantially boosts protection against Covid, the company reports. The New York Times. https://www.nytimes.com/2021/09/21/health/johnson-and-johnson-shot.html
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Community-Based Research Shows More People Exposed to COVID-19 Virus Than Previously Known: Institute for Policy Research - Northwestern University. (2021, April 13). https://www.ipr.northwestern.edu/news/2021/scan-study-preliminary-findings-of-levels-of-protective-immunity-sars-cov-2.html
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Regev-Yochay, G., Gonen, T., Gilboa, M., Mandelboim, M., Indenbaum, V., Amit, S., Meltzer, L., Asraf, K., Cohen, C., Fluss, R., Biber, A., Nemet, I., Kliker, L., Joseph, G., Doolman, R., Mendelson, E., Freedman, L. S., Harats, D., Kreiss, Y., & Lustig, Y. (2022). 4th Dose COVID mRNA Vaccines’ Immunogenicity & Efficacy Against Omicron VOC (p. 2022.02.15.22270948). medRxiv. https://doi.org/10.1101/2022.02.15.22270948
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Collier, A. Y., Brown, C. M., Mcmahan, K., Yu, J., Liu, J., Jacob-Dolan, C., Chandrashekar, A., Tierney, D., Ansel, J. L., Rowe, M., Sellers, D., Ahmad, K., Aguayo, R., Anioke, T., Gardner, S., Siamatu, M., Rivera, L. B., Hacker, M. R., Madoff, L. C., & Barouch, D. H. (2021). Immune Responses in Fully Vaccinated Individuals Following Breakthrough Infection with the SARS-CoV-2 Delta Variant in Provincetown, Massachusetts (p. 2021.10.18.21265113). https://doi.org/10.1101/2021.10.18.21265113
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Dean, N. E. (2021, September 21). Hmm okay. J&J two dose results are a bit more complicated, with different results globally versus within the US. https://t.co/prFUorU8LE [Tweet]. @nataliexdean. https://twitter.com/nataliexdean/status/1440318770665324560
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Sample, I. (2022, January 25). Long Covid: Doctors find ‘antibody signature’ for patients most at risk. The Guardian. https://www.theguardian.com/society/2022/jan/25/doctors-find-antibody-signature-long-covid
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Gallagher, J. (2021, November 14). Covid vaccine ‘waning immunity’: How worried should I be? BBC News. https://www.bbc.com/news/health-59260294
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ReconfigBehSci. (2021, December 12). RT @EricTopol: If you think Prior Covid protects against Omicron (B.1.1.529), think again https://medrxiv.org/content/10.1101/2021.12.08.21267491v1 and "Neutralizing antibo… [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1470434736304803845
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- Apr 2022
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Payne, R. P., Longet, S., Austin, J. A., Skelly, D. T., Dejnirattisai, W., Adele, S., Meardon, N., Faustini, S., Al-Taei, S., Moore, S. C., Tipton, T., Hering, L. M., Angyal, A., Brown, R., Nicols, A. R., Gillson, N., Dobson, S. L., Amini, A., Supasa, P., … Zawia, A. A. T. (2021). Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine. Cell, 184(23), 5699-5714.e11. https://doi.org/10.1016/j.cell.2021.10.011
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Ravi K Gupta [@ravgup33_ravi]. (2021, November 24). This one is worrying and I’ve not said that since delta. Please get vaccinated and boosted and mask up in public as the mutations in this virus likely result in high level escape from neutralising antibodies [Tweet]. Twitter. https://twitter.com/ravgup33_ravi/status/1463626745651806208
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Tao, K., Tzou, P. L., Nouhin, J., Gupta, R. K., de Oliveira, T., Kosakovsky Pond, S. L., Fera, D., & Shafer, R. W. (2021). The biological and clinical significance of emerging SARS-CoV-2 variants. Nature Reviews Genetics, 1–17. https://doi.org/10.1038/s41576-021-00408-x
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Pavord, S., Hunt, B. J., Horner, D., Bewley, S., & Karpusheff, J. (2021). Vaccine induced immune thrombocytopenia and thrombosis: Summary of NICE guidance. BMJ, 375, n2195. https://doi.org/10.1136/bmj.n2195
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- Mar 2022
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Lauren Pelley. (2022, February 24). BREAKING: Made-in-Canada #COVID19 vaccine from Medicago approved by Health Canada today. Shot dubbed ‘Covifenz,’ and uses virus-like particles. Background on the high efficacy against infection seen during Phase 3 clinical trials: Https://t.co/5clkYzatVK [Tweet]. @LaurenPelley. https://twitter.com/LaurenPelley/status/1496859590402654208
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- Feb 2022
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twitter.com twitter.com
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ReconfigBehSci on Twitter: ‘surprising how the logic of argument around C19 has not updated to the fact that reinfection is a big thing, as are new variants. Delay = a round of infection you never got...’ / Twitter. (n.d.). Retrieved 13 February 2022, from https://twitter.com/SciBeh/status/1483716840316706824
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Mahase, E. (2022). Covid-19: What do we know about omicron sublineages? BMJ, 376, o358. https://doi.org/10.1136/bmj.o358
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- Jan 2022
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Gentles, L. E., Kehoe, L., Crawford, K. H. D., Lacombe, K., Dickerson, J., Wolf, C., Yuan, J., Schuler, S., Watson, J. T., Nyanseor, S., Briggs-Hagen, M., Saydah, S., Midgley, C. M., Pringle, K., Chu, H., Bloom, J. D., & Englund, J. A. (2022). Dynamics of infection-elicited SARS-CoV-2 antibodies in children over time (p. 2022.01.14.22269235). medRxiv. https://doi.org/10.1101/2022.01.14.22269235
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Taylor, L. (2022). Covid-19: CoronaVac immunity is strongest after boosting with a different vaccine. BMJ, 376, o210. https://doi.org/10.1136/bmj.o210
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Wernike, K., Boettcher, J., Amelung, S., Albrecht, K., Gaertner, T., Donat, K., & Beer, M. (2022). Serological screening suggests single SARS-CoV-2 spillover events to cattle (p. 2022.01.17.476608). https://doi.org/10.1101/2022.01.17.476608
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Liu, Y., Ebinger, J. E., Mostafa, R., Budde, P., Gajewski, J., Walker, B., Joung, S., Wu, M., Bräutigam, M., Hesping, F., Rupieper, E., Schubert, A.-S., Zucht, H.-D., Braun, J., Melmed, G. Y., Sobhani, K., Arditi, M., Van Eyk, J. E., Cheng, S., & Fert-Bober, J. (2021). Paradoxical sex-specific patterns of autoantibody response to SARS-CoV-2 infection. Journal of Translational Medicine, 19(1), 524. https://doi.org/10.1186/s12967-021-03184-8
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Glenn Beck has Covid again after refusing vaccine: ‘It’s going into my lungs.’ (2022, January 13). The Independent. https://www.independent.co.uk/news/world/americas/us-politics/glenn-beck-covid-ivermectin-mark-levin-b1992427.html
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- Dec 2021
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Richterman, A., Scott, J., & Cevik, M. (2021). Covid-19 vaccines, immunity, and boosters. BMJ, 375, n3105. https://doi.org/10.1136/bmj.n3105
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Reuters. (2021, December 20). Moderna says booster produces strong antibody response to Omicron. The Guardian. https://www.theguardian.com/world/2021/dec/20/moderna-booster-strong-antibody-response-omicron-covid-vaccine-variant
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www.medrxiv.org www.medrxiv.org11779531
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Garcia-Beltran, W. F., Denis, K. J. S., Hoelzemer, A., Lam, E. C., Nitido, A. D., Sheehan, M. L., Berrios, C., Ofoman, O., Chang, C. C., Hauser, B. M., Feldman, J., Gregory, D. J., Poznansky, M. C., Schmidt, A. G., Iafrate, A. J., Naranbhai, V., & Balazs, A. B. (2021). MRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant (p. 2021.12.14.21267755). https://doi.org/10.1101/2021.12.14.21267755
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ReconfigBehSci. (2021, December 12). RT @florian_krammer: New preprint led by Kaori Sano in collaboration with @VivianaSimonLab https://medrxiv.org/content/10.1101/2021.12.06.21267352v1. Convalescent individual… [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1469936301466079233
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Mahase, E. (2021). Covid-19: Do vaccines work against omicron—and other questions answered. BMJ, 375, n3062. https://doi.org/10.1136/bmj.n3062
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Roessler, A., Riepler, L., Bante, D., Laer, D. von, & Kimpel, J. (2021). SARS-CoV-2 B.1.1.529 variant (Omicron) evades neutralization by sera from vaccinated and convalescent individuals (p. 2021.12.08.21267491). https://doi.org/10.1101/2021.12.08.21267491
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www.bmj.com www.bmj.com
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Mahase, E. (2021). Covid-19: Antibody boost after third dose varies greatly by vaccine, study finds. BMJ, 375, n3011. https://doi.org/10.1136/bmj.n3011
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www.irishtimes.com www.irishtimes.com
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GSK-Vir antibody-based Covid-19 treatment works against Omicron variant. (n.d.). The Irish Times. Retrieved December 2, 2021, from https://www.irishtimes.com/business/health-pharma/gsk-vir-antibody-based-covid-19-treatment-works-against-omicron-variant-1.4744831
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- Nov 2021
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www.nature.com www.nature.com
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Mallapaty, S. (2021). The coronavirus is rife in common US deer. Nature. https://doi.org/10.1038/d41586-021-02110-8
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twitter.com twitter.com
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ReconfigBehSci. (2021, November 1). 2/2 from the paper ‘We speculate that the extraordinarily high antibody titers observed in vaccinated individuals who develop breakthrough infections may lead to subsequent long-term protection in those individuals.’ [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1455104597454954497
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- Oct 2021
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www.bmj.com www.bmj.com
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Mahase, E. (2021). Covid-19: Just a third of blood cancer patients had antibodies against delta variant after two vaccine doses, study finds. BMJ, 375, n2623. https://doi.org/10.1136/bmj.n2623
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twitter.com twitter.com
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John Roberts on Twitter. (n.d.). Twitter. Retrieved 31 October 2021, from https://twitter.com/john_actuary/status/1453289464441233422
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Andreano, E., Paciello, I., Piccini, G., Manganaro, N., Pileri, P., Hyseni, I., Leonardi, M., Pantano, E., Abbiento, V., Benincasa, L., Giglioli, G., De Santi, C., Fabbiani, M., Rancan, I., Tumbarello, M., Montagnani, F., Sala, C., Montomoli, E., & Rappuoli, R. (2021). Hybrid immunity improves B cells and antibodies against SARS-CoV-2 variants. Nature, 1–7. https://doi.org/10.1038/s41586-021-04117-7
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twitter.com twitter.com
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Prof. Akiko Iwasaki. (2021, September 23). Thankfully, we have not seen any evidence of antibody-dependent enhancement of infection or disease by any COVID vaccines to date. Vaccine are not making infections worse, and are very effective in preventing disease. [Tweet]. @VirusesImmunity. https://twitter.com/VirusesImmunity/status/1441074260534075392
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China’s ‘zero Covid’ vs Singapore’s ‘living with it’: Rapid low-cost testing could mean we don’t need to choose | South China Morning Post. (n.d.). Retrieved October 15, 2021, from https://www.scmp.com/comment/opinion/article/3152167/chinas-zero-covid-vs-singapores-living-it-rapid-low-cost-testing
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Mahase, E. (2021). Covid-19: Antibody levels fall after second Pfizer dose, but protection against severe disease remains, studies indicate. BMJ, 375, n2481. https://doi.org/10.1136/bmj.n2481
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www.medpagetoday.com www.medpagetoday.com
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Should the Unvaccinated Get Priority for Monoclonal Antibodies? (2021, October 8). https://www.medpagetoday.com/infectiousdisease/covid19/94937
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www.science.org www.science.org
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Mateus, J., Dan, J. M., Zhang, Z., Rydyznski Moderbacher, C., Lammers, M., Goodwin, B., Sette, A., Crotty, S., & Weiskopf, D. (n.d.). Low-dose mRNA-1273 COVID-19 vaccine generates durable memory enhanced by cross-reactive T cells. Science, 0(0), eabj9853. https://doi.org/10.1126/science.abj9853
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fullfact.org fullfact.org
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Full Fact. ‘What Do We Know about the Covid-19 Vaccines Crossing the Placenta?’, 16:58:51+00:00. https://fullfact.org/pregnant-then-screwed/vaccines-crossing-placenta/.
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Emary, K. R. W., Golubchik, T., Aley, P. K., Ariani, C. V., Angus, B., Bibi, S., Blane, B., Bonsall, D., Cicconi, P., Charlton, S., Clutterbuck, E. A., Collins, A. M., Cox, T., Darton, T. C., Dold, C., Douglas, A. D., Duncan, C. J. A., Ewer, K. J., Flaxman, A. L., … Pollard, A. J. (2021). Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial. The Lancet, 0(0). https://doi.org/10.1016/S0140-6736(21)00628-0
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00628-0/fulltext
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Yahoo Finance. (2021, September 21). “The J&J results exceed expectations,” Yale Radiology and Public Health Professor @thehowie says about the COVID-19 vaccine. “They continue to point out that the J&J vaccine is highly effective even as a one dose vaccine.” https://t.co/AOsxo9IwKT [Tweet]. @YahooFinance. https://twitter.com/YahooFinance/status/1440356401826590727
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- Sep 2021
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www.theguardian.com www.theguardian.com
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Geddes, L. (2021, September 28). Covid can infect cells in pancreas that make insulin, research shows. The Guardian. https://www.theguardian.com/society/2021/sep/29/covid-can-infect-cells-in-pancreas-that-make-insulin-research-shows
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Dupuy, B. (2021, August 6). COVID-19 vaccines offer benefits even to those previously infected. AP NEWS. https://apnews.com/article/fact-checking-130053228518
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www.newscientist.com www.newscientist.com
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Klein, Alice. “Cheap Covid-19 Antibody Test Shows If You Have Immunity in 5 Minutes.” New Scientist. Accessed September 20, 2021. https://www.newscientist.com/article/2290120-cheap-covid-19-antibody-test-shows-if-you-have-immunity-in-5-minutes/.
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Wilson, C. (2021, September 9). Blood test could reveal who is most likely to get severe covid-19. New Scientist. https://www.newscientist.com/article/2289718-blood-test-could-reveal-who-is-most-likely-to-get-severe-covid-19/
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www.science.org www.science.org
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Israelow, B., Mao, T., Klein, J., Song, E., Menasche, B., Omer, S. B., & Iwasaki, A. (2021). Adaptive immune determinants of viral clearance and protection in mouse models of SARS-CoV-2. Science Immunology. https://doi.org/10.1126/sciimmunol.abl4509
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John Burn-Murdoch. (2021, August 23). NEW: in the last couple of weeks there have a lot of new studies out assessing vaccine efficacy, many of which have touched on the question of waning immunity. Unsurprisingly, these have prompted a lot of questions. Time for a thread to summarise what we do and don’t know: [Tweet]. @jburnmurdoch. https://twitter.com/jburnmurdoch/status/1429878189011111936
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- Aug 2021
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www.biorxiv.org www.biorxiv.org
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Liu, Y., Arase, N., Kishikawa, J., Hirose, M., Li, S., Tada, A., Matsuoka, S., Arakawa, A., Akamatsu, K., Ono, C., Jin, H., Kishida, K., Nakai, W., Kohyama, M., Nakagawa, A., Yamagishi, Y., Nakagami, H., Kumanogoh, A., Matsuura, Y., … Arase, H. (2021). The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines (p. 2021.08.22.457114). https://doi.org/10.1101/2021.08.22.457114
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www.thelancet.com www.thelancet.com
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Madhi, S. A., Koen, A. L., Izu, A., Fairlie, L., Cutland, C. L., Baillie, V., Padayachee, S. D., Dheda, K., Barnabas, S. L., Bhorat, Q. E., Briner, C., Aley, P. K., Bhikha, S., Hermanus, T., Horne, E., Jose, A., Kgagudi, P., Lambe, T., Masenya, M., … Kwatra, G. (2021). Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in people living with and without HIV in South Africa: An interim analysis of a randomised, double-blind, placebo-controlled, phase 1B/2A trial. The Lancet HIV, 0(0). https://doi.org/10.1016/S2352-3018(21)00157-0
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www.theguardian.com www.theguardian.com
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We shouldn’t be giving Covid boosters while millions wait for a first dose | Andrew Pollard and Seth Berkley | The Guardian. (n.d.). Retrieved August 17, 2021, from https://www.theguardian.com/commentisfree/2021/aug/13/covid-boosters-dose-vaccine
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www.medrxiv.org www.medrxiv.org
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Hillus, David, Tatjana Schwarz, Pinkus Tober-Lau, Hana Hastor, Charlotte Thibeault, Stefanie Kasper, Elisa T. Helbig, et al. “Safety, Reactogenicity, and Immunogenicity of Homologous and Heterologous Prime-Boost Immunisation with ChAdOx1-NCoV19 and BNT162b2: A Prospective Cohort Study,” June 2, 2021. https://doi.org/10.1101/2021.05.19.21257334.
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Prof. Devi Sridhar. “Rest of the World Watching Closely: ‘In Scotland, Estimated That 92.5% of Adults Would Have Tested Positive for Antibodies against SARS-CoV-2 on a Blood Test in the Week Beginning 12 July 2021’- Is This Enough to Dampen Transmission & Protect under 12s from Infection? Under 18s?” Tweet. @devisridhar (blog), August 4, 2021. https://twitter.com/devisridhar/status/1422852550957617157.
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Greinacher, A., Thiele, T., Warkentin, T. E., Weisser, K., Kyrle, P. A., & Eichinger, S. (2021). Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination. New England Journal of Medicine, 384(22), 2092–2101. https://doi.org/10.1056/NEJMoa2104840
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Shrotri, M., Navaratnam, A. M. D., Nguyen, V., Byrne, T., Geismar, C., Fragaszy, E., Beale, S., Fong, W. L. E., Patel, P., Kovar, J., Hayward, A. C., & Aldridge, R. W. (2021). Spike-antibody waning after second dose of BNT162b2 or ChAdOx1. The Lancet, 398(10298), 385–387. https://doi.org/10.1016/S0140-6736(21)01642-1
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