38 Matching Annotations
  1. Mar 2022
  2. Feb 2022
    1. There's a common design flaw on many many websites that require an email address to register; most recently I came across this bug on CNet's download.com site: for some reason they don't accept me when I try to register an email address containing a "+", and they then send me back saying my address is invalid. It isn't!
  3. Dec 2021
  4. Oct 2021
    1. Meuris, C., Kremer, C., Geerinck, A., Locquet, M., Bruyère, O., Defêche, J., Meex, C., Hayette, M.-P., Duchene, L., Dellot, P., Azarzar, S., Maréchal, N., Sauvage, A.-S., Frippiat, F., Giot, J.-B., Léonard, P., Fombellida, K., Moutschen, M., Durkin, K., … Darcis, G. (2021). Transmission of SARS-CoV-2 After COVID-19 Screening and Mitigation Measures for Primary School Children Attending School in Liège, Belgium. JAMA Network Open, 4(10), e2128757. https://doi.org/10.1001/jamanetworkopen.2021.28757

  5. Jun 2021
  6. May 2021
  7. Feb 2021
  8. Oct 2020
  9. Sep 2020
  10. Aug 2020
    1. Ferretti, A. P., Kula, T., Wang, Y., Nguyen, D. M., Weinheimer, A., Dunlap, G. S., Xu, Q., Nabilsi, N., Perullo, C. R., Cristofaro, A. W., Whitton, H. J., Virbasius, A., Olivier, K. J., Baiamonte, L. B., Alistar, A. T., Whitman, E. D., Bertino, S. A., Chattopadhyay, S., & MacBeath, G. (2020). COVID-19 Patients Form Memory CD8+ T Cells that Recognize a Small Set of Shared Immunodominant Epitopes in SARS-CoV-2. MedRxiv, 2020.07.24.20161653. https://doi.org/10.1101/2020.07.24.20161653

  11. Jun 2020
  12. May 2020
    1. Döhla, M., Boesecke, C., Schulte, B., Diegmann, C., Sib, E., Richter, E., Eschbach-Bludau, M., Aldabbagh, S., Marx, B., Eis-Hübinger, A.-M., Schmithausen, R. M., & Streeck, H. (2020). Rapid point-of-care testing for SARS-CoV-2 in a community screening setting shows low sensitivity. Public Health. https://doi.org/10.1016/j.puhe.2020.04.009

    1. Arons, M. M., Hatfield, K. M., Reddy, S. C., Kimball, A., James, A., Jacobs, J. R., Taylor, J., Spicer, K., Bardossy, A. C., Oakley, L. P., Tanwar, S., Dyal, J. W., Harney, J., Chisty, Z., Bell, J. M., Methner, M., Paul, P., Carlson, C. M., McLaughlin, H. P., … Jernigan, J. A. (2020). Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing Facility. New England Journal of Medicine, NEJMoa2008457. https://doi.org/10.1056/NEJMoa2008457

    1. Gudbjartsson, D. F., Helgason, A., Jonsson, H., Magnusson, O. T., Melsted, P., Norddahl, G. L., Saemundsdottir, J., Sigurdsson, A., Sulem, P., Agustsdottir, A. B., Eiriksdottir, B., Fridriksdottir, R., Gardarsdottir, E. E., Georgsson, G., Gretarsdottir, O. S., Gudmundsson, K. R., Gunnarsdottir, T. R., Gylfason, A., Holm, H., … Stefansson, K. (2020). Spread of SARS-CoV-2 in the Icelandic Population. New England Journal of Medicine, NEJMoa2006100. https://doi.org/10.1056/NEJMoa2006100

  13. Apr 2020
    1. The hit rate was found to be much lower thanthat of the fragment screen

      the author implied that fragment screening usually has higher hit rate than drug size library screening.

    2. a hit rate of about 4%

      hit rate of 4% by DSF is similar to that of screening against kinase targets, interesting.

    3. fragment library

      fragment screening for binders are really powerful. this library contains 800 fragments

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  14. Mar 2020