800 Matching Annotations
  1. Sep 2022
    1. "detail": [ { "loc": [ "body", "name" ], "message": "Field required" }, { "loc": [ "body", "email" ], "message": "'not-email' is not an 'email'" } ]

      not complient with Problem Details, which requires details to be a string

    1. FetchErrorResponse: type: object properties: meta: $ref: '#/definitions/FetchMetaResponse' errors: $ref: '#/definitions/Error' example: { "meta": { "req_id": "d07c8b12-c95e-4a06-8424-92aac94bb445" }, "errors": [{ "code": "Unauthorized", "detail": "A valid bearer token is required", "status":"401" } ] }
    1. Above all, a fresh and original intellectual approach is needed, avoid-ing all standard solutions.

      This relates to the increasing difficulty of being originial with the rapid advances in productivity today.

    2. A striving for order can, and must, also be expressed inasymmetrical form.

      This relates to sticking to past foundations that are somewhat indispensable.

    3. Thetypographer must take the greatest care to study how his work is read andought to be read.

      Today, this is foundational since there are constantly advances in works of typography making documentation and research important to giving future credit.

    4. Evenin good central-axis composition the contents are subordinated to “beautifulline arrangement.”

      Clarity becomes less important due the focus on the composition being centralized as it relates to improving the visual appeal of the artistic, "arrangement."

    5. the rigidity of central-axis setting hardly allows work tobe carried out with the degree of logic we now demand.

      The central axis in art relates to a somewhat balanced distribution of space on an art piece.

      “ARTTALK Chapter 10 Balance - Ppt Google Img.” SlidePlayer, https://slideplayer.com/slide/10709291/.

    6. This utmost clarity is necessarytoday because of the manifold claims for our attention made by the extraor-dinary amount of print, which demands the greatest economy of expression.

      This emphasizes that having clear communication is made crucially important due to the difficulty of communicating to those who are surrounded by countless other "prints."

    1. Author response

      To: Reviewer: Heikki Vapaatalo, MD, PhD, Emeritus professor of Pharmacolog

      Dear reviewer Thank you very much for the insightful suggestions, the manuscript improved a lot with the changes performed. Please find the point-by-point answer to the raised questions. In the main text, all changes are highlighted in yellow. I hope that with the changes made the new version is suitable for publication.

      Best regards Valquiria Bueno

      General assessment

      The study is interesting and the title promises for me more than the MS finally contains.

      Answer: The manuscript is part of a project aiming to study ACE1 and ACE2 expression in cells from the immune system of aging and young adults. These initial results suggest that ACE1 (and probably ACE2) plays somehow a role in the process of aging.

      The background, question and the aim are relevant as explained in the introduction.

      Answer: We included a piece of information in the “Introduction” trying to link ACE1 expression in tissue cells and age-related diseases, as it follows:

      ACE1 has been suggested to influence age-related diseases (i.e. Alzheimer’s, sarcopenia, cancer) but the associated mechanisms are still under investigation. ACE1 polymorphisms were correlated with susceptibility to Alzheimer’s disease (AD). [15, 16] In addition, it was shown recently that in normal aging ACE1 expression is increased in brain homogenates and this expression is unchanged in early stages of AD. [17] Regarding sarcopenia, Yoshihara et al. [18] found a weak correlation between ACE polymorphism and physical function. In cancer (gastric or colorectal), patients presented higher expression of ECA1 in tumor when compared with healthy tissues. [19, 20]

      The major criticism concerns the small size of the material (subjects, n=6), the small age difference (64-67 years) and the lack of younger controls.

      Answer: We agree that the small number of studied subjects is a limitation of this study. In spite of the interesting results suggesting that ACE1 expression could be linked to the health status, it was not possible to perform correlation analysis due to the small sample size. Even though there is a small chronological difference between the subjects, the biological aging is very different among them and reflects the genetics, lifestyle, nutrition and comorbidities. Another limitation is the lack of younger controls to compare with the subjects studied. Our next steps are to include younger controls, to increase the number of studied subjects, and if possible to get samples from older subjects (i.e. 70-80, 80 and more years old)

      Minor notes:

      1)Title: Angiotensin converting enzyme (ACE) expression in leukocytes of older adults

      Answer: We evaluated only ACE1 expression, and thus, title, abstract, and main text were changed to ACE1 instead of ACE. We decided to change to title for: Angiotensin converting enzyme (ACE) 1 expression in leukocytes of adults from 64 to 67 years old

      2)Introduction: The last chapter, the Author should explain in more detail, how references 11-14 suggest that “ACE play an important role in the aging process”. Does this mean, that ACE is somehow regulating the aging process or in increasing age ACE -levels are changed?

      Answer: References 11-14 shows that age-related diseases occurring in older adults are associated with changes in the immune system. To complete the text we added:

      ACE1 has been suggested to influence age-related diseases (i.e. Alzheimer’s, sarcopenia, cancer) but the associated mechanisms are still under investigation. ACE1 polymorphisms were correlated with susceptibility to Alzheimer’s disease (AD). [15, 16] In addition, it was shown recently that in normal aging ACE1 expression is increased in brain homogenates and this expression is unchanged in early stages of AD. [17] Regarding sarcopenia, Yoshihara et al. [18] found a weak correlation between ACE polymorphism and physical function. In cancer (gastric or colorectal), patients presented higher expression of ECA1 in tumor when compared with healthy tissues. [19, 20]

      Material and Methods:

      The N-value of the subjects should be mentioned here, as well the relation of females/males.

      Answer: Text was correct as suggested Blood was collected from adults (n=6, four females and two males) aged 64-67 years old in 2015.

      Do the Authors really regard 64-67 “older age” nowadays?

      Answer: Nowadays the most common term used for individuals older than 65 years is “older adults”.

      Why first many years later the assays have been done in comparison to the collection of the blood? Are the samples still useable, not destroyed?

      Answer: Samples are part of UNIFESP Biobank and have been kept in adequate conditions. We wanted to test cells from a period anterior to COVID-19 and those samples were the only ones that attended our purpose. We compared samples used in this study with fresh blood samples (cell viability and percentage of CD4+, CD8+ and CD19+) and the results showed good preservation of the cells.

      Did the subjects have some diseases and/or drugs because the possibly were from hospital sample bank?

      Answer: Samples are part of UNIFESP Biobank, but unfortunately we do not have information about diseases and medicaments.

      Express the company details similarly than Amersham, cities and countries.

      Answer: Changes were done as required ACE CD143 FITC (R&D Systems, Inc, Minneapolis, USA)


      “Table 1 shows that older adults…..” The comparison between the present data and historical studies belongs to the Discussion.

      Answer: Changes were done as required

      Give also individual ages and gender of the subjects in the table 1.

      Answer: The manuscript version sent to medrxiv@medrxiv.org had age and gender on tables, but due to their request, any possible variable that could identify the studied individual had to be removed. That is why in the present version these variables are not shown.

      What means p-values here? Compared with which or interindividual differences in the particular variable? Should be explained

      Answer: We used p-value for interindividual differences in each variable since individuals age differently (biological aging) and thus, physiological parameters could be affected by genetics, lifestyle, nutrition, and comorbidities. It is now explained in materials and methods

      The numbering of tables and the text seems to me confusing. Only three tables, but in the text mentioned four. Number 4 does not exist.

      Answer: For some reason table 2 is missing in the main text, please find the new version with Table 2 included

      It would be good to have a list of abbreviations used in the description of the cell types for an unfamiliar reader.

      Answer: In each figure and table we are now providing a description of cells evaluated.


      A major part of the discussion deals with previous publications and not meaning or clinical significance of the present findings and comparison between the present and earlier studies.

      Answer: The discussion was changed as suggested:

      Our results show that for the studied population, chronological aging and biological aging don´t go at the same pace. Even individuals having a small chronological difference (64 to 67 years old), they are heterogeneous for physiological parameters such as glucose, urea, glycated hemoglobin (Hbglic), and C-reactive protein (CRP). Changes in the same functional parameters have been reported by Carlsson et al. [22] and Helmerson-Karlqvist [23] in healthy older adults. Carlsson’s study [22] found that CRP value was 2.6 with a coefficient variation of 1.4% whereas in our study, it was observed higher values of CRP in 5 out of 6 individuals. Increased CRP levels has been associated with inflammaging and our findings show that the studied population has changes in functional parameters which are likely associated with an inflammatory profile. [24] The link between RAS and inflammation has been suggested but its role is not completely clear under physiological and pathological conditions. [25, 26] In addition, the association between ACE1 altered expression in tissues (brain, muscle, heart and vessels) and the development and progression of age-related conditions such as Alzheimer’s, sarcopenia, and cardiovascular disease has been suggested but results are controversial. [17, 27, 28, 29, 30] There are few studies showing the association between ACE1 expression in cells from the immune system (monocytes, T cells) and the progression of kidney and cardiovascular disease. [9, 8, 31, 32]. Therefore, considering the lack of information on this issue, we questioned whether ACE1 (CD143) was highly expressed in cells from the immune system during the aging process. We found that ACE1 was expressed in almost 100% of T (CD4+, CD8+) and B lymphocytes and in all phenotypes of these cells. In non-lymphoid cells, ACE1 mean expression was 56,9%. In agreement with our findings, independent studies showed that T cells from healthy donors and monocytes from patients with congestive heart failure expressed ACE1, but there was no investigation on cell phenotype. [25, 26]. Our study is the first to show that either inexperienced (naive) or fully activated (memory) cells expresses ACE1. Our findings suggest a that the expression of ACE1 in lymphoid and non-lymphoid cells reflects the health status since our studied population presented changes in physiological parameters and high levels of ACE1 expression on immune cells. Previous independent studies showed that patients with unstable angina [32] or acute myocardial infarction [33] presented higher expression of ACE1 in T cells and dendritic cells than controls subjects. In addition, markers of the cell (lymphoid and non-lymphoid) functional status such as inflammatory or growth factors production could be modulated by ACE inhibitors (ACEi). Accordingly, mononuclear leukocytes from healthy subjects incubated with endotoxin exhibited high levels of tissue factor activity which was reduced in the presence of captopril in a dose-dependent pattern. This result could be related to the antithrombotic effect of ACEi. [34]. In patients with congestive heart failure, immune cells cultured with LPS secreted high levels of the pro-inflammatory TNF-alpha and these levels were significantly reduced in the presence of captopril. [35]

      In those previous studies, also ACE2 has been reported, why not studied here?

      Answer: Our next studies will be focused on ACE1 and ACE2 expression in cells from the immune system in both younger and older adults.

      In the limitations, the Authors fairly mention the real problem: The small sample size, and I would like to say lack of younger subjects.

      Answer: we agree with the limitations pointed and the text was changed as required:

      This study have limitations such as the small sample size and the lack of young adults for comparison. As an example, the subject with the highest CRP and albumin also exhibited a high percentage of ACE1 expression on T (CD4+, CD8+), B and non-lymphoid cells in addition to the lowest percentage of CD4+ naive cells, and the highest percentage of CD8+ terminally differentiated (EMRA) and DN B cells. However, due to the small sample size it was not possible to associate the high expression of ACE1 on immune cells with inflammaging and immunosenescence. It would bring important information to correlate physiological parameters/health status with ACE1 expression and to find out whether age and associated chronic diseases could lead to increased ACE1 expression.

      The COVID-19 point even tempting today, is too far from this study and unnecessary. Answer: Our point was to emphasize the negative impact of chronic diseases for the outcome of aging population during a viral infection and how ACE1/ACE2 expression could bring information to diagnosis and treatment. Therefore, we would like to maintain this piece of information.

      Linguistic checking would improve the MS. Answer: We checked for possible linguistic mistakes

      Reviewer, Heikki Vapaatalo:

      I read with pleasure the very detailed answers to my comments.

      I very warmly recommend acceptance of this MS for publications without any further notes.

      Decision changed:

      Verified manuscript: The content is scientifically sound, only minor amendments (if any) are suggested.

  2. Aug 2022
    1. Lucas, C., Vogels, C. B. F., Yildirim, I., Rothman, J. E., Lu, P., Monteiro, V., Gelhausen, J. R., Campbell, M., Silva, J., Tabachikova, A., Peña-Hernandez, M. A., Muenker, M. C., Breban, M. I., Fauver, J. R., Mohanty, S., Huang, J., Shaw, A. C., Ko, A. I., Omer, S. B., … Iwasaki, A. (2021). Impact of circulating SARS-CoV-2 variants on mRNA vaccine-induced immunity. Nature, 1–9. https://doi.org/10.1038/s41586-021-04085-y

    1. Munro, A. P. S., Janani, L., Cornelius, V., Aley, P. K., Babbage, G., Baxter, D., Bula, M., Cathie, K., Chatterjee, K., Dodd, K., Enever, Y., Gokani, K., Goodman, A. L., Green, C. A., Harndahl, L., Haughney, J., Hicks, A., van der Klaauw, A. A., Kwok, J., … Appleby, K. (2021). Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): A blinded, multicentre, randomised, controlled, phase 2 trial. The Lancet, S0140673621027173. https://doi.org/10.1016/S0140-6736(21)02717-3 s

    1. Sadoff, J., Gars, M. L., Cardenas, V., Shukarev, G., Vaissiere, N., Heerwegh, D., Truyers, C., Groot, A. M. de, Scheper, G., Hendriks, J., Ruiz-Guinazu, J., Struyf, F., Hoof, J. V., Douoguih, M., & Schuitemaker, H. (2021). Durability of antibody responses elicited by a single dose of Ad26.COV2.S and substantial increase following late boosting (p. 2021.08.25.21262569). https://doi.org/10.1101/2021.08.25.21262569

    1. Thuluva, S., Paradkar, V., Turaga, K., Gunneri, S., Yerroju, V., Mogulla, R., Kyasani, M., Manoharan, S. K., Medigeshi, G., Singh, J., Shaman, H., Singh, C., & Rao, A. V. (2022). Selection of optimum formulation of RBD-based protein sub-unit covid19 vaccine (Corbevax) based on safety and immunogenicity in an open-label, randomized Phase-1 and 2 clinical studies (p. 2022.03.08.22271822). medRxiv. https://doi.org/10.1101/2022.03.08.22271822

    1. Krause, P. R., Fleming, T. R., Peto, R., Longini, I. M., Figueroa, J. P., Sterne, J. A. C., Cravioto, A., Rees, H., Higgins, J. P. T., Boutron, I., Pan, H., Gruber, M. F., Arora, N., Kazi, F., Gaspar, R., Swaminathan, S., Ryan, M. J., & Henao-Restrepo, A.-M. (2021). Considerations in boosting COVID-19 vaccine immune responses. The Lancet, 4. https://doi.org/10.1016/S0140-6736(21)02046-8

    1. Collier, A. Y., Brown, C. M., Mcmahan, K., Yu, J., Liu, J., Jacob-Dolan, C., Chandrashekar, A., Tierney, D., Ansel, J. L., Rowe, M., Sellers, D., Ahmad, K., Aguayo, R., Anioke, T., Gardner, S., Siamatu, M., Rivera, L. B., Hacker, M. R., Madoff, L. C., & Barouch, D. H. (2021). Immune Responses in Fully Vaccinated Individuals Following Breakthrough Infection with the SARS-CoV-2 Delta Variant in Provincetown, Massachusetts (p. 2021.10.18.21265113). https://doi.org/10.1101/2021.10.18.21265113

    1. John Bye [@_johnbye]. (2021, October 6). The new covid sceptic All Party Parliamentary Group on Pandemic Response and Recovery is backed by Gupta and Heneghan’s Collateral Global to the tune of over £30,000. £5,000 in financial benefits plus £25,501—£27,000 benefits in kind (CG is acting as their secretariat). Https://t.co/qll20Sg9aA [Tweet]. Twitter. https://twitter.com/_johnbye/status/1445867760819396608

    1. And this system of linguistic competenceis qualitatively different from anything that can be described in terms of thetaxonomic methods of structural linguistics, the concepts of S-R psychology,or the notions developed within the mathematical theory of communication orthe theory of simple automata.

      What are the atomic building blocks that would allow stimulus-response psychology to show complex behaviors?

    1. Maker Governance moved fast to vote in Debt Auction parameter fixes and changes and additions to the system. The community quickly launched further analytic tools, allowing observers to better follow system fixes and changes. See the changelog.  The zero-bid events of March 12-13 led to a collateral auction shortfall amounting to approximately 5.4M+ Dai. Around 1,200 Maker Vaults became under-collateralized and were subsequently liquidated. As noted above, the Maker community is currently discussing the circumstances surrounding the zero bids and resulting liquidations

      How Maker resaponded to the mempool manipulation

  3. Jun 2022
    1. I have wasted my life.

      Well...OK, this is the gut punch. From my own personal experience on my farm, I feel the same. This morning I saw a a pair of juvenile greater blue herons flying across the creek and then gone. We have at least three nesting pairs of herons on our farm down by the same creek. I feel a wildly inappropriate sense of having helped this brand new mated pair of herons come into being. And then I feel that nothing else in my academic life compares to that. I, too, have wasted my life. It is not a reasonable line of argument. It is a gut feelilng as Wright lays the earlier observational truth upon us. Who can stand in the wake of nature's creative force? Pan always wins.

      And the other side of that line is one that says, "It is my life to 'waste'. What you call waste is all of the glorioius connection. A culture that does not value this simple idleness, that condemns it, that is the waste.

  4. May 2022
    1. The three key enablers of the hyperthreat—its invisibility, its ability to evade all existing human threat-response mechanisms, and human hesitancy—will be targeted with three corresponding lines of effort, which will be pursued across multiple task groups:10 Make the hyperthreat visible and knowable; Reduce hyperthreat freedom of action; and Achieve mass and speed of response.

      This is a salient division to create a series of collective actions: make it visible so that we can respond to the threat in a timely and effective manner.

  5. Apr 2022
    1. Mathew, D., Giles, J. R., Baxter, A. E., Oldridge, D. A., Greenplate, A. R., Wu, J. E., Alanio, C., Kuri-Cervantes, L., Pampena, M. B., D’Andrea, K., Manne, S., Chen, Z., Huang, Y. J., Reilly, J. P., Weisman, A. R., Ittner, C. A. G., Kuthuru, O., Dougherty, J., Nzingha, K., … Wherry, E. J. (2020). Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications. Science, 369(6508), eabc8511. https://doi.org/10.1126/science.abc8511

    1. ReconfigBehSci. (2021, November 2). @jeremy_hume personally, I’d consider it a natural, considerate, and moral response to avoid contact with others when carrying an infection that can be dangerous to others. So what seems dystopian to me, is not doing so, and not creating the social/financial conditions that allow it. [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1455499076850655235

  6. Mar 2022
    1. ReconfigBehSci on Twitter: ‘@STWorg @ProfColinDavis @rpancost @chrisdc77 @syrpis this is the most in depth treatment of the impact of equalities law on pandemic policy that I’ve been able to find- it would seem to underscore that there is a legal need for impact assessments that ask (some) of these questions https://t.co/auiApVC0TW’ / Twitter. (n.d.). Retrieved 22 March 2022, from https://twitter.com/SciBeh/status/1485927221449613314

  7. Feb 2022
    1. Dr. Deepti Gurdasani. (2022, February 21). Did anyone hear any mention of long COVID, an illness affecting 1.3 million people, of whom 500,000 have had this for more than a year during the briefing? Are we just going to pretend it doesn’t exist? [Tweet]. @dgurdasani1. https://twitter.com/dgurdasani1/status/1495839416262311938

    1. But it isn’t. This is because over such a long period a message can easily be distorted or altered without this being in any way intended. (This distortion or alteration in the meaning or method of transmission of a message, whether intended or not, is called “noise.”) Languages, both written and spoken, always change. The meanings of symbols are often lost in the passage of time. In fact, most messages are bound so closely to a particular period and place that even a short time later they cannot be understood. Therefore, ensuring that a message created now can be decoded by future generations is highly problematic.

      Can symbol that represents one thing change over a long period of time to mean something different?

    2. ea. It is only because there is already a well-established connection in our minds between the appearance of an apple and the idea of temptation that this fruit is used in the picture. It is this connection that makes the picture successful in terms of communicatio

      Why was the apple chosen as the representation of temptation?

    3. semiotician,

      A Theory of signs and symbols that deals especially with there function in both artificially constructed and natural languages.

    1. That is, the first thing he asked of this particular object was not “How should it look?” but “What must it do?” and to that extent all good typography is modernist.

      Typography is not about how it should look but rather how it can convey the message.

    2. because everything about it is calculated to reveal rather than to hide the beautiful thing that it was meant to contain.

      I like this statement because when it comes to typography it is meant to reveal the beauty behind the design.

    3. that the most important thing about printing is that it conveys thought, ideas, images, from one mind to other minds.

      It's true that if you can transfer your thought and ideas in your design, your audience would be able to understand your message.

    4. maudlin experiments

      self-pityingly or tearfully sentimental, often through drunkenness.

    5. impudent

      Not showing due respect for another person or being impertinent

    6. When a goblet has a base that looks too small for security, it does not matter how cleverly it is weighted; you feel nervous lest it should tip over. There are ways of setting lines of type that may work well enough, and yet keep the reader subconsciously worried by the fear of “doubling” lines, reading three words as one, and so forth.

      The writer seems to to talking about the reader of a design becoming overwelmed by the text in a design when they look at it if there is to much causing the message of the design to be lost or not focused on in the design.

    7. Digital technology puts creation, production, and distribution into the hands of the designer, enabling such bold assertions of artistic presence. These acts of graphic authorship fit within a broader evolving model of collective author-ship that is fundamentally changing the producer-consumer relationship.

      What role does technology play in shaping design?

      Because of the technological advances that we have made, technology has helped designers to re-imagine the impossible.

      Technology has helped us to create the impossible.

    8. Today some graphic designers continue to champion ideals of neutrality and objectivity that were essential to the early formation of their field. Such designers see the client’s message as the central component of their work. They strive to communicate this message clearly, although now their post-postmodern eyes are open to the impossibility of neutrality and objectivity.

      What distinguishes the field, or fields, of design from other creative occupations?

      I think that creativity is key for distinguishing the difference between design and other occupation.

      As a designer you have to be neutral and creative in getting your clients message across.

    9. Looking back across the history of design through the minds of these influential designers, one can identify pervasive themes like those discussed in this introduction. Issues like authorship, universality, and social responsi-bility, so key to avant-garde ideology, remain crucial to contemporary critical and theoretical discussions of the field.

      According to this author, what role should design play in society?

      I think that the author was talking about how the design community should be the new avant-garde.

      I think that designers should be at the forefront of the design community.

    1. ReconfigBehSci. (2022, January 14). man who contracted potentially disease and then violated public health orders tries to cross borders by providing incorrect info on key docs = just fine is not something I foresaw from this corner... Once consistency is thrown out as a standard, rational debate is impossible... [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1481929150042619908

    1. Timothy Caulfield. (2022, January 31). How Do You Respond When an #AntiVaxxer Dies of Covid? Https://nytimes.com/2022/01/30/opinion/culture/covid-death-mental-health.html?smid=tw-share by @JamesMartinSJ “Indulged in regularly, #schadenfreude ends up warping the soul.” “Don’t find another person’s misery the subject of mirth, glee or satisfaction.” Good reminder. One I needed. [Tweet]. @CaulfieldTim. https://twitter.com/CaulfieldTim/status/1488183630056755205

  8. Jan 2022
    1. Gentles, L. E., Kehoe, L., Crawford, K. H. D., Lacombe, K., Dickerson, J., Wolf, C., Yuan, J., Schuler, S., Watson, J. T., Nyanseor, S., Briggs-Hagen, M., Saydah, S., Midgley, C. M., Pringle, K., Chu, H., Bloom, J. D., & Englund, J. A. (2022). Dynamics of infection-elicited SARS-CoV-2 antibodies in children over time (p. 2022.01.14.22269235). medRxiv. https://doi.org/10.1101/2022.01.14.22269235

    1. Dr. Thrasher wrote a book! (2022, January 8). My cousin wanted to get tested. She waited in an auto testing line for 6.5 hours, and stayed in it bc she was traveling to bury her Daddy. How many people give up in such long lines? How many cases upwards of a million are we losing bc Biden et all failed on home tests? Https://t.co/Q7WVy5qD4v [Tweet]. @thrasherxy. https://twitter.com/thrasherxy/status/1479826389142491146

    1. ReconfigBehSci. (2022, January 9). Just a thought on this and the general vaccine mandate debate. As a behavioural scientist currently stuck in Germany where this is a live debate, it strikes me that the thoughts below address only part of the population: Those not currently vaccinated. But what about ... 1/2 [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1480213148032450565

    1. ReconfigBehSci. (2022, January 9). There are many things I would not have believed about the pandemic pre 2020, but top of them is the fact that Western nations would completely ignore 24 months worth of actually implemented policies that were vastly more successful [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1480162136240398339

    1. Home

      Zuo, F., Abolhassani, H., Du, L., Piralla, A., Bertoglio, F., Campos-Mata, L. de, Wan, H., Schubert, M., Wang, Y., Sun, R., Cassaniti, I., Vlachiotis, S., Kumagai-Braesch, M., Andréll, J., Zhang, Z., Xue, Y., Wenzel, E. V., Calzolai, L., Varani, L., … Pan-Hammarström, Q. (2022). Heterologous immunization with inactivated vaccine followed by mRNA booster elicits strong humoral and cellular immune responses against the SARS-CoV-2 Omicron variant (p. 2022.01.04.22268755). https://doi.org/10.1101/2022.01.04.22268755

    1. Will Stancil. (2022, January 11). The US reported 1.4 million COVID cases yesterday and hospitalizations are the highest ever. We’re sailing into this hurricane with virtually no effort to change course because fancy people believe they have a god-given right to their normal lives, no matter how bad things get. [Tweet]. @whstancil. https://twitter.com/whstancil/status/1480914594243792904