Clinical trials will most certainly first include those patients with the highest risk of relapse. However, long term, everything will depend on the risk/ benefit trade off: if an effective, simple, well-tolerated and cost-effective treatment was available (let's imagine a single short low-dose PD1 for any early Melanoma patient) that prevented progression for most patients would be very different from a highly toxic, expensive treatment that doesn't work for everyone (think Ipi 10mg/kg adjuvant)- so everything is in the trade-off

keywords

Evokes distributed cognition (Hutchins) as well as the uncertain nature of safety- and time-critical work and how to classify risk/need.

A visual exploration of the link between statin use and the risk of Diabetes in a subpopulation of patients with subclinical hypothyroidism.

This is an interactive graph created with Biovista Vizit; nodes and links can be further explored to view supporting bibliography and molecular mechanism of action.

This shows between a 65% to 272% increased risk of miscarriage from use of common antibiotics.

The risk is being characterized as "small' - http://www.cnn.com/2017/05/01/health/antibiotics-miscarriage-study/

I'm not sure any pregnant woman would characterize more than doubling of the risk as small, and we can assume that if this data was shown for a natural substance, it would be characterized differently.

The study that is hyperlinked in this article takes you to a blog post on the Harvard Medical School Prostate Knowlegde blog. They didn't do the study, but they wrote a post about two studies that were conducted on the topic and gave references, which made it nice to follow. After reading the two studies, i found that this title tends to be misleading in its statement. Both studies conducted found that men who ejaculate more than either 7 times per week or more than 21 times a month have a decreased risk of prostate cancer. To me, this is not regular orgasms, that amount seems to be on the higher end for most people and hard to continue through out your life. In conclusion, yes, more ejaculations can reduce your risk of prostate cancer, but the amount needed is high and must be started at a young age to fully reap the benefits.

APA References:

Giles, G.G., Severi, G., English, D.R., McCredie, M.R.E., Borland, R., Boyle, P., & Hopper, J.L. (2003). Sexual factors and prostate cancer. BJU International, 92(3), 211-216.

Leitzmann, M.F., Platz, E.A., Stampfer, M.J., Willett, W.C., Giovannucci, E. (2004). Ejaculation frequency and subsequent risk of prostate cancer. JAMA: Journal of the American Medical Association, 291(13), 1578-1586.

Links: http://jamanetwork.com/journals/jama/fullarticle/198487?=quot;,gt;

http://onlinelibrary.wiley.com/doi/10.1046/j.1464-410X.2003.04319.x/full

Another facet/form of risk.

I think this is key. The only alternative to argument is a risk--to risk one's self by making their narrative plain and facing the possibility that the other will reject one's narrative (and thereby reject one's personhood.

The difference between the previous steps to avoid argument and this one is that this one advocates risk and seems to make no promise of resolution.

Taking the risk to be open.

Feeling of being uncomfortable when first confronted with explaining a potential project - that reminds me of conversations with Maritta and Leena.

Need to create a risk management plan associated with the use of predictive analytics. Talking as an organization about the risks is important - that way we can help keep each other responsible for using analytics in a responsible way.

Algal bloom is noted by the EPA as a major environmental problem. Essentially, algal blooms are overgrowths of algae. Of course, a natural phenomenon such as this does not know political boundaries, and thus information given on Algal Bloom by the EPA is as valid in Canada as it is in the U.S. Algal blooms are also known as red tides, cyanobacteria, or blue-green algae. Algal blooms are commonly toxic, and the EPA advises people and other animals stay away from water sources that look like they may have algal bloom occurring. This water is commonly green, bad smelling, or scummy. Algal bloom can occur in both marine environments and fresh water environments. In fact, in both these environments, even non-toxic algal blooms can affect the economy and environment. This is because algal blooms can create “dead zones” in the environment they are present in. They also make treatment of drinking water much harder, raising costs of that process. They also hurt industries that rely on clean water to operate. Algal blooms essentially need three things to occur: slow moving water, sunlight, and nutrients. These nutrients include nitrogen and phosphorus. In terms of specific effects of the harmful algal bloom, the human health consequences can be seen as symptoms such as: respiratory problems, stomach illness, liver illness, rashes, and neurological effects. Children drinking nitrates (a common element in algal bloom water) is also very dangerous. Dioxins, which are used to treat water contaminated with the elements of algal bloom, can also be dangerous.

EPA. “Harmful Algal Blooms”. Last modified January 23, 2017. https://www.epa.gov/nutrientpollution/harmful-algal-blooms

To perform his ethos puts him at risk.

These "endangering possibilities" are the focus of much of the Enlightenment thinkers we will shortly engage.

source: https://s3.amazonaws.com/prod_foundationapp/364221/lessons/35/1384378776-john-carlton-1.pdf

from: https://campus.thefoundation.com/courses/1/lessons/35

it's a shame that teachers may be hesitant to elevate the discourse amongst students out of fear of repercussions due to idealogy

The conditions and process described here mirrors the process many organizations go through in an attempt to cut costs by trying to cut through what is perceived as marketing-hype. The cost differences are compelling enough to continually tempt people down a path to considerably reduce costs while believing that they've done enough due-diligence to avoid raising the risk to an unacceptable level.