Rational optimism regarding our future, then, is only possible to the extent we can find prior evolutionary steps which are plausibly more improbable than they look. Conversely, without such findings we must consider the possibility that we have yet to pass through a substantial part of the Great Filter. If so, then our prospects are bleak, but knowing this fact may at least help us improve our chances. For example, if our prospects are likely bleak we should search out and take especially seriously any plausible scenarios, such as nuclear war or ecological collapse, which might lead to our future inability to explode across the universe. A long list of such scenarios for concern can be found in [Leslie 96]. Our main data point, the Great Silence, would be telling us that at least one of these scenarios is much more probable than it otherwise looks. With such a warning in hand, we might, for example, take extra care to protect our ecosystems, perhaps even at substantial expense to our economic growth rate. We might be even especially cautious regarding the possibility of world-destroying physics experiments. And we might place a much higher priority on projects like Biosphere 2, which may allow some part of humanity to survive a great disaster.

The earlier a serious Manhattan-like project to develop nanotechnology is initiated, the longer it will take to complete, because the earlier you start, the lower the foundation from which you begin. The actual project will then run for longer, and that will then mean more time for preparation: serious preparation only starts when the project starts, and the sooner the project starts, the longer it will take, so the longer the preparation time will be. And that suggests that we should push as hard as we can to get this product launched immediately, to maximize time for preparation.

the Center for the 01:00:29 Study of existential risk dedicated the study and mitigation of risks that could lead to human extinction or civilizational collapse and the interesting thing is that modernity is 01:00:41 not on their list either in fact it's not on the list of any of the agencies that now are dedicated to do this work