- Jun 2023
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www.carbonbrief.org www.carbonbrief.org
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Dr Sokhna Thiam, from the African Population and Health Research Center in Nairobi, Kenya, added that water-borne enteric diseases are among the “primary expected health impacts” of climate change.
Basically climate changes makes the leading cause of child deaths much worse
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- May 2023
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www.gimjournal.org www.gimjournal.org
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Figure 1Optical genome mapping reveals 173 Mb pericentric inversion on chromosome 1 with a breakpoint within the USH2A gene.
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Structural variants (SVs) play an important role in inherited retinal diseases (IRD).
Structural variants, specifically CNVs (Copy Number Variants) contribute to more than 10% of undiagnosed IRD cases
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- Feb 2023
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www.biorxiv.org www.biorxiv.org
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Review coordinated by Life Science Editors.
Reviewed by: Dr. Angela Andersen, Life Science Editors
Potential Conflicts of Interest: Dr. Mill has worked with Life Science Editors on other manuscripts.
Background: Retinitis pigmentosa (RP) is a group of rare eye diseases that cause vision loss. Symptoms usually start in childhood, and most people eventually lose most of their sight. There is no cure for RP. Mutations in retinitis pigmentosa GTPase regulator (RPGR) cause RP and compromise the renewal of light-sensitive “disc” membranes (specialized cilia) at the outer segment of photoreceptors, resulting in the loss of these cells over time. Evidence suggests that disc formation is similar to the release of ectosomes (small extracellular vesicles) and that both rely on the actin cytoskeleton. Knockdown of RPGR in retinal pigmented epithelium cells showed stronger actin filaments and reduced cilia suggesting that it may regulate nascent photoreceptor disc formation by regulating actin-mediated membrane extension in the retina (Gakovic et al., Human Molecular Genetics, 2011). In addition, RPGR patient iPSC-retinal models displayed phenotypes consistent with abnormal actin regulation (Megaw et al., Nature Communications, 2017; Karam et al., J Personalized Medicine, 2022).
Question: What function of RPGR is compromised in photoreceptors to cause RP?
Advance: The authors generated novel Rpgr mutant mice harboring human disease-causing mutations that recapitulate human disease phenotypes: aborted membrane shedding as ectosome-like vesicles, photoreceptor death and visual loss. RPGR is located at the site of disc formation – to test if it plays a role in disc genesis, they engineered a novel reporter mouse to track outer segment turnover. Rhodopsin was tagged with the self-labelling peptide SNAP- Rhodopsin is the major protein component of outer segment discs, and so incubating RhodSNAP retinal slice cultures with SNAP fluorophores results in outer segment labelling. Perturbation of RPGR resulted in a slowed rate of disc formation, leading to shortened outer segments and increased vesicle shedding. To me, the breakthrough is in the last figure: the actin depolymerizing drug Cytochalasin D in PBS was injected intravitreally, and fixed retinas were analyzed 6 hours later by electron microscopy. Cytochalasin D treatment significantly reduced the number of shed vesicles from the base of the outer segment in Rpgr-mutant mice (they now look like wild-type).
Significance: Nails down the disease-relevant function of RPGR and a molecular mechanism of RP in photoreceptor cells, in vivo, in mice. Pharmacological rescue not only demonstrates the importance of the mechanism to disease but also sheds light on a potential therapeutic avenue for RP.
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- Jan 2023
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docdrop.org docdrop.org
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the numbers are 00:14:09 something like that you drop it down to you've got 88 percent less chance or actually it's it's 12 percent chance for most diseases so most diseases are protected by these diets
!- vegan and pescatarian diets : disease impacts - reduce by 88%
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- Dec 2022
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www.danielpipes.org www.danielpipes.org
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The polio-vaccine conspiracy theory has had direct consequences: Sixteen countries where polio had been eradicated have in recent months reported outbreaks of the disease – twelve in Africa (Benin, Botswana, Burkina Faso, Cameroon, Central African Republic, Chad, Ethiopia, Ghana, Guinea, Mali, Sudan, and Togo) and four in Asia (India, Indonesia, Saudi Arabia, and Yemen). Yemen has had the largest polio outbreak, with more than 83 cases since April. The WHO calls this "a major epidemic."
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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I came here after recalling a critique by Bessel van der Kolk's "The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma" regarding the disease model and it's negative impact on adequately helping people with trauma. van der Kolk's critique was similar to Marc Lewis' critique of the disease model as it applies to addiction from "The Biology of Desire: Why Addiction Is Not a Disease". This made me wonder what the term "disease" actually means and whether or not some general consensus existed within the medical community. This article suggests there is no such consensus.
This article is by Jackie Leach Scully who holds a "PhD in cellular pathology, University of Cambridge; BA (Hons) in biochemistry, University of Oxford; MA in psychoanalytic studies, Sheffield University".
Scully does several insightful things in this paper the following are the ones that were most salient to me upon the first read: - distinguishes "disease" from "disability" - contrasts the "social model" and "medical model" perspectives on "disability" - The "medical model" referred to here is probably what Lewis & van der Kolk are critiquing as the "disease model".<br /> - Are the "medical" and "disease" model different? - the social model seems to have arisen as a response to the inadequacy of the medical model
- "The social model's fundamental criticism of the medical model is that it wrongly locates 'the problem' of disability in biological constraints, considering it only from the point of view of the individual and neglecting the social and systemic frameworks that contribute to it. The social model distinguishes between impairment (the biological substrate, such as impaired hearing) and the disabled experience. In this view the presence of impaired hearing is one thing, while the absence of subtitling on TV is quite another, and it is the refusal of society to make the necessary accommodations that is the real site of disability. A social model does not ignore biology, but contends that societal, economic and environmental factors are at least as important in producing disability."- brings up a subtle point that there are two jumps "from gene to phenotype, and from phenotype to experience" and that some of the arguments mentioned "suggest that the 'harm' of the impairment is not straightforwardly related to phenotype. What ought to concern us about disease and disability is the disadvantage, pain or suffering involved, and in a sense the impairment is always a kind of surrogate marker for this experience."
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www.sciencedirect.com www.sciencedirect.com
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OMIM 612718
Case#: pt I, 21 y/o male
DiseaseAssertion: GAMT deficiency
FamilyInfo:non-consangeous parents of Yemenite Jewish descent
CasePresentingHPOs: expressive speech was delayed, reduced strength and stamina, delayed general cognitive function
CaseHPOFreeText: N/A
CaseNotHPOs:N/A
CaseNotHPOFreeText: N/A
Biochemical analyte testing: abnormal CK and EMG results
Brain Magnetic Resonance Spectroscopy (MRS): appeared normal
GAMT activity assay: N/A
Zygosity: autosomal recessive
Variant 1: OMIM 612718
ClinVarID: N/A
CAID: N/A
gnomAD: N/A
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academic.oup.com academic.oup.com
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OMIM 300352)
Case#: N/A
DiseaseAssertion: AGAT mutation
FamilyInfo: N/A
CasePresentingHPOs: N/A
CaseHPOFreeText: N/A
CaseNotHPOs: N/A
CaseNotHPOFreeText: N/A
Biochemical analyte testing: N/A
Brain Magnetic Resonance Spectroscopy (MRS): N/A
GAMT activity assay: N/A
Zygosity: homozygous
Variant 1: OMIM 602360
ClinVarID: 8303
CAID: CA340769
gnomAD: N/A
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OMIM 601240
Case#: N/A
DiseaseAssertion: AGAT mutation
FamilyInfo: N/A
CasePresentingHPOs: N/A
CaseHPOFreeText: N/A
CaseNotHPOs: N/A
CaseNotHPOFreeText: N/A
Biochemical analyte testing: N/A
Brain Magnetic Resonance Spectroscopy (MRS): N/A
GAMT activity assay: N/A
Zygosity: homozygous
Variant 1: OMIM 602360
ClinVarID: 8303
CAID: CA340769
gnomAD: N/A
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OMIM 602360
Case#: N/A
DiseaseAssertion: AGAT mutation
FamilyInfo: N/A
CasePresentingHPOs: N/A
CaseHPOFreeText: N/A
CaseNotHPOs: N/A
CaseNotHPOFreeText: N/A
Biochemical analyte testing: N/A
Brain Magnetic Resonance Spectroscopy (MRS): N/A
GAMT activity assay: N/A
Zygosity: homozygous
Variant 1: OMIM 602360
ClinVarID: 8303
CAID: CA340769
gnomAD: N/A
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- Nov 2022
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Local file Local file
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Use of predictive algorithms in-homemonitoring of chronic obstructivepulmonary disease and asthma:A systematic review
Use of predictive algorithms in-home monitoring of chronic obstructive pulmonary disease and asthma: A systematic review
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- Oct 2022
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clinicalgenome.org clinicalgenome.org
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seen by the original user, not by
A case of: Disease assertion: family information: case presenting:
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- Sep 2022
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The underlying theme tyingthese myths together is that poverty is often perceived to be an issue of“them” rather than an issue of “us”—that those who experience povertyare viewed as strangers to mainstream America, falling outside accept-able behavior, and as such, are to be scorned and stigmatized.
One of the underlying commonalities about the various myths of poverty is that we tend to "other" those that it effects. The "them" we stigmatize with the ills of poverty really look more like "us", and in fact, they are.
Rather than victim shame and blame those in poverty, we ought to spend more of our time fixing the underlying disease instead of spending the time, effort, energy, and money on attempting to remedy the symptoms (eg. excessive policing, et al.) Not only is it more beneficial, but cheaper in the long run.
Related:<br /> Gladwell, Malcolm. “Million-Dollar Murray.” The New Yorker, February 5, 2006. https://www.newyorker.com/magazine/2006/02/13/million-dollar-murray (.pdf copy available at https://housingmatterssc.org/million-dollar-murray/)
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- Aug 2022
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www.abc.net.au www.abc.net.au
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Willis, O. (2021, October 19). The pandemic won’t end with a bang, but more likely a fizzle. Here’s how. ABC News. https://www.abc.net.au/news/health/2021-10-20/covid-19-pandemic-when-does-it-end-become-endemic-like-flu/100549816
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twitter.com twitter.com
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www.medrxiv.org www.medrxiv.org
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Regev-Yochay, G., Gonen, T., Gilboa, M., Mandelboim, M., Indenbaum, V., Amit, S., Meltzer, L., Asraf, K., Cohen, C., Fluss, R., Biber, A., Nemet, I., Kliker, L., Joseph, G., Doolman, R., Mendelson, E., Freedman, L. S., Harats, D., Kreiss, Y., & Lustig, Y. (2022). 4th Dose COVID mRNA Vaccines’ Immunogenicity & Efficacy Against Omicron VOC (p. 2022.02.15.22270948). medRxiv. https://doi.org/10.1101/2022.02.15.22270948
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www.medrxiv.org www.medrxiv.org
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Bays, D., Whiteley, T., Pindar, M., Taylor, J., Walker, B., Williams, H., Finnie, T. J. R., & Gent, N. (2021). Mitigating isolation: The use of rapid antigen testing to reduce the impact of self-isolation periods (p. 2021.12.23.21268326). medRxiv. https://doi.org/10.1101/2021.12.23.21268326
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www.washingtonpost.com www.washingtonpost.com
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Hamblin, J. (2021, December 9). Perspective | Omicron won’t keep us from ending the pandemic. We’re doing that ourselves. Washington Post. https://www.washingtonpost.com/outlook/2021/12/09/omicron-coronavirus-individual-threat/
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www.npr.org www.npr.org
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Huang, P. (2021, April 1). How The CDC Is Battling The Pandemic And Working To Regain Public Trust: Shots—Health News: NPR. https://www.npr.org/sections/health-shots/2021/04/01/982761755/inside-the-cdcs-battle-to-defeat-the-virus?utm_campaign=storyshare&utm_source=twitter.com&utm_medium=social
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www.washingtonpost.com www.washingtonpost.com
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Perspective | Even the best-case scenario with omicron will still be bad. (n.d.). Washington Post. Retrieved December 23, 2021, from https://www.washingtonpost.com/outlook/2021/12/21/omicron-mild-cases-numbers/
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twitter.com twitter.com
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ReconfigBehSci on Twitter: "RT @vmcorman: “...With nearly 5 million children ages 5 to 11 now vaccinated against COVID-19, Centers for Disease Control and Prevention D…” / Twitter. (n.d.). Retrieved December 13, 2021, from https://twitter.com/SciBeh/status/1470066664301637632
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twitter.com twitter.com
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ReconfigBehSci on Twitter: “RT @acweyand: Kids account for <0.2% of cancer deaths in US Kids account for <0.2% of heart disease deaths in US Kids account for <0.3% of…” / Twitter. (n.d.). Retrieved January 21, 2022, from https://twitter.com/SciBeh/status/1483869918332432388
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- May 2022
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Pathogenic germline variants in DICER1 underlie an autosomal dominant, pleiotropic tumor-predisposition disorder.
gene name: DICER 1 PMID (PubMed ID): 33570641 HGNCID: n/a Inheritance Pattern: autosomal dominant Disease Entity: benign and malignant tumor mutation Mutation: somatic Zygosity: heterozygous Variant: n/a Family Information: n/a Case: people of all sexes, ages, ethnicities and races participated CasePresentingHPOs: individuals with DICER1-associated tumors or pathogenic germline DICER1 variants were recruited to participate CasePreviousTesting: n/a gnomAD: n/a
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watermark.silverchair.com watermark.silverchair.com
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DICER1 syndrome is an autosomal-dominant,pleiotropic, tumor-predisposition disorder arisingfrom pathogenic germline variants in DICER1, whichencodes an endoribonuclease integral to processingmicroRNAs
DICER1 is the gene name. PubMed ID, HGCNCID, and Variant: I can't find Inheritance Pattern: autosomal-dominant The disease entity: DICER1 syndrome The type of mutation: germline. Zygosity: not known. Family Information: a family was used, DICER1 carriers, and non DICER1 variant used, some of the family members had tumors from DICER1 Case Information: mean age is 34, the range of age is 18.6 to 43 years, male, and female used, ethnicity can't find Case Presenting HPO: cancer testing, chemotherapy, radiotherapy gnomeAD: 9.2,8.3.2 Mutation type: Pleiotropic, loss of function, missense
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Embryonal rhabdomyosarcoma (ERMS) of the uterus has recently been shown to frequently harbor DICER1 mutations.
HGNCID:
Tags
- Inheritance Pattern: Non- inheritance(DNA methylation)
- Mutation: 5428 G>C
- Variant: Clinvar ID not identified
- Mutation: c.4267G>T
- case mut: f 28-67
- Zygosity: Some Cases displayed homozygosity
- Mutation: c.5438 A> C
- pathogenicity: only 2 of 17 patients died from disease
- Mutation: c5113G>A
- Mutation: c.5428G>T
- Family Information: not identified
- Mutation: c.3580delA
- Disease Entity: Embryonal rhabdomyosarcoma (ERMS)
- Mutation: c.4420A>G
- GeneName: DICER1
- Mutation: c.5125G > A
- case wt: m&f 0.5-19
- PMID (PubMed ID): 33846547
Annotators
URL
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- Apr 2022
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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long COVID
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SARS-CoV-2
Tags
Annotators
URL
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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DICER1 syndrome is an autosomal-dominant, pleiotropic tumor-predisposition disorder
Gene Name:DICER1 PMID: 30715996 HGNCID: Not on document Inheritance Pattern: Autosomal Dominant Disease Entity: Pleiotropic Tumor-Predisposition Disorder Mutation: Pathogenic Germline Variants Zygosity: Not in document Variant: Not in document Family Information: An individual was found who had family members who were also affected by this mutation. Because of this, those family members were also chosen to participate in this study. Mutation Type: Missense Case: The study was done on more than one individual. Roughly more than half of the individuals were female
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www.science.org www.science.org
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Mathew, D., Giles, J. R., Baxter, A. E., Oldridge, D. A., Greenplate, A. R., Wu, J. E., Alanio, C., Kuri-Cervantes, L., Pampena, M. B., D’Andrea, K., Manne, S., Chen, Z., Huang, Y. J., Reilly, J. P., Weisman, A. R., Ittner, C. A. G., Kuthuru, O., Dougherty, J., Nzingha, K., … Wherry, E. J. (2020). Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications. Science, 369(6508), eabc8511. https://doi.org/10.1126/science.abc8511
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pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
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Taylor, S. (2021). The Psychology of Pandemics. Annual Review of Clinical Psychology. https://doi.org/10.1146/annurev-clinpsy-072720-020131
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twitter.com twitter.com
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Dr. Deepti Gurdasani. (2022, January 24). When did 4.5% of children in any age group being infected every wk become ok for any disease? [Tweet]. @dgurdasani1. https://twitter.com/dgurdasani1/status/1485670994320793602
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twitter.com twitter.com
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Freja Kirsebom. (2022, January 28). Two important updates from our team this week: - Vaccine effectiveness (VE) against symptomatic disease after Omicron BA.2 shows that VE remains unchanged—VE against death after Omicron BA.1 shows VE is 95% at 2+ weeks after booster 1/7 Full report https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1050721/Vaccine-surveillance-report-week-4.pdf [Tweet]. @freja_kirsebom. https://twitter.com/freja_kirsebom/status/1486730977464369160
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video.ibm.com video.ibm.com
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Advisory Committee on Immunization Practices- ACIP. (n.d.). Retrieved April 27, 2022, from https://video.ibm.com/channel/VWBXKBR8af4
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www.cdc.gov www.cdc.gov
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Lindsley, W. G. (2021). Efficacy of Portable Air Cleaners and Masking for Reducing Indoor Exposure to Simulated Exhaled SARS-CoV-2 Aerosols—United States, 2021. MMWR. Morbidity and Mortality Weekly Report, 70. https://doi.org/10.15585/mmwr.mm7027e1
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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The DICER1 syndrome is an autosomal dominant tumor‐predisposi-tion disorder associated with pleuropulmonary blastoma, a rare pediatric lung cancer
GeneName:DICER1 PMID (PubMed ID): PMCID: PMC6418698 PMID: 30672147 HGNCID: NOT LISTED<br /> Inheritance Pattern: Autosomal Dominant Disease Entity: Cancer; benign and malignant tumors including pleuropulmonary blastoma, cystic nephroma, Sertoli-Leydig cell tumors, multinodular goiter, Thryoid cancer, rhabdomyosarcoma, and pineoblastoma. Mutation: Somatic missense variation Mutation type: missense Zygosity: None stated Variant: unregistered…. Family Information: Characterize germline variants in familial early-onset clorectal cancer patients; The observation of germline DICER1 variation with uterine corpus endometrial carcinoma merits additional investigation. CasePresentingHPOs: uterine and rectal cancers in germline mutation
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twitter.com twitter.com
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Prof Francois Balloux [@BallouxFrancois]. (2021, December 9). This may have sounded somewhat naïve in early 2020, but by now, I would have expected that anyone with an interest in covid-19 might have acquired some basic notions in infectious disease epidemiology. 1/ [Tweet]. Twitter. https://twitter.com/BallouxFrancois/status/1469063480334561285
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www.nature.com www.nature.com
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Levine-Tiefenbrun, M., Yelin, I., Alapi, H., Katz, R., Herzel, E., Kuint, J., Chodick, G., Gazit, S., Patalon, T., & Kishony, R. (2021). Viral loads of Delta-variant SARS-CoV-2 breakthrough infections after vaccination and booster with BNT162b2. Nature Medicine, 1–3. https://doi.org/10.1038/s41591-021-01575-4
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www.covid-datascience.com www.covid-datascience.com
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Morris, J. (2021, August 17). Israeli data: How can efficacy vs. severe disease be strong when 60% of hospitalized are vaccinated? Covid Data Science. https://www.covid-datascience.com/post/israeli-data-how-can-efficacy-vs-severe-disease-be-strong-when-60-of-hospitalized-are-vaccinated
Tags
- symptomatic
- surge
- age
- COVID-19
- Pfizer
- lang:en
- vaccine
- hospitalization
- severe disease
- efficacy
- is:blog
- asymptomatic
- variant
- dose
- delta
- risk
- effective
Annotators
URL
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twitter.com twitter.com
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Carl T. Bergstrom. (2021, August 18). 1. There has been lots of talk about recent data from Israel that seem to suggest a decline in vaccine efficacy against severe disease due to Delta, waning protection, or both. This may have even been a motivation for Biden’s announcement that the US would be adopting boosters. [Tweet]. @CT_Bergstrom. https://twitter.com/CT_Bergstrom/status/1427767356600688646
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www.cdc.gov www.cdc.gov
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Excess Deaths Associated with COVID-19. (2021, February 17). https://www.cdc.gov/nchs/nvss/vsrr/covid19/excess_deaths.htm
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twitter.com twitter.com
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Dr Greg Kelly. (2021, July 2). As a pediatrician I’m going on record saying that allowing kids to be freely infected with a novel disease that has unknown long term consequences is the worst idea of 2021 despite being a pretty crowded field so far #COVID19 [Tweet]. @drgregkelly. https://twitter.com/drgregkelly/status/1411083905034117120
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twitter.com twitter.com
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ReconfigBehSci. (2021, January 29). RT @IndependentSage: 3.7 million infected with #COVID19 in the UK. An estimated 5-10% will develop #LongCovid. We can’t afford to ignore th… [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1355097550529945607
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Callaway, E. (2021). Heavily mutated Omicron variant puts scientists on alert. Nature, 600(7887), 21–21. https://doi.org/10.1038/d41586-021-03552-w
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- Mar 2022
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www.bccdc.ca www.bccdc.ca
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Getting a Vaccine. (n.d.). Retrieved 31 March 2022, from http://www.bccdc.ca/health-info/diseases-conditions/covid-19/covid-19-vaccine/getting-a-vaccine#under12
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Study finds brain changes similarly to Alzheimer’s after COVID-19. (n.d.). The Jerusalem Post | JPost.Com. Retrieved March 31, 2022, from https://www.jpost.com/health-and-wellness/coronavirus/article-696565
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www.theguardian.com www.theguardian.com
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Sample, I., & editor, I. S. S. (2022, March 10). UK Covid cases rising among those aged 55 and over. The Guardian. https://www.theguardian.com/world/2022/mar/10/uk-covid-cases-rising-among-those-aged-55-and-over
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twitter.com twitter.com
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Dr. Deepti Gurdasani. (2022, March 1). New study out yesterday suggesting that vaccine efficacy with current dose for 5-11 yr olds likely wanes quickly. Especially against infection, but also against hospitalisation, although protection against severe disease is higher. Seems to be closely linked to vaccine dose🧵 https://t.co/NojLODF1ED [Tweet]. @dgurdasani1. https://twitter.com/dgurdasani1/status/1498580243665367040
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psyarxiv.com psyarxiv.com
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Lehnen, N., Glasauer, S., Schröder, L., Regnath, F., Biersack, K., Bergh, O. V. den, & Werder, D. von. (2022). Post-COVID symptoms in the absence of organic deficit—Lessons from diseases we know. PsyArXiv. https://doi.org/10.31234/osf.io/yqar2
Tags
- brain
- symptom
- COVID-19
- persistent symptoms
- lang:en
- severe symptoms
- fatigue
- post-COVID
- body signals
- organic deficit
- disease
- long COVID
- predictive coding
- breathlessness
- body symptoms
- experience
- interoception
- organic impairment
- is:preprint
- dizziness
- experimental paradigm
- rebreathing
- informational processing
- perception
Annotators
URL
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twitter.com twitter.com
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ReconfigBehSci on Twitter: ‘this really is now a disinformation account. I retweeted posts earlier in the pandemic as part of a balanced spread of opinion. But this will be the last one...’ / Twitter. (n.d.). Retrieved 29 March 2022, from https://twitter.com/SciBeh/status/1478485258395951108
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name. (n.d.). På trods af historisk høje smittetal følger indlæggelserne ikke med. Retrieved 28 March 2022, from https://www.ssi.dk/aktuelt/nyheder/2022/paa-trods-af-hoeje-smittetal-foelger-indlaeggelserne-ikke-med
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www.pnas.org www.pnas.org
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Kerr, P. J., Cattadori, I. M., Liu, J., Sim, D. G., Dodds, J. W., Brooks, J. W., Kennett, M. J., Holmes, E. C., & Read, A. F. (2017). Next step in the ongoing arms race between myxoma virus and wild rabbits in Australia is a novel disease phenotype. Proceedings of the National Academy of Sciences, 114(35), 9397–9402. https://doi.org/10.1073/pnas.1710336114
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twitter.com twitter.com
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ReconfigBehSci. (2022, January 20). @OmicronData @timcolbourn I think there might be a difference here between what you are putting forward and what @timcolbourn is arguing any rational individual should be for analysing the expected costs and benefits of a course of action, and I assume we all agree on that. 1/2 [Tweet]. @i. https://twitter.com/i/web/status/1484080972459134976
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twitter.com twitter.com
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ReconfigBehSci on Twitter: ‘@STWorg @ProfColinDavis @rpancost @chrisdc77 @syrpis this is the most in depth treatment of the impact of equalities law on pandemic policy that I’ve been able to find- it would seem to underscore that there is a legal need for impact assessments that ask (some) of these questions https://t.co/auiApVC0TW’ / Twitter. (n.d.). Retrieved 22 March 2022, from https://twitter.com/SciBeh/status/1485927221449613314
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Halilova, J. G., Fynes-Clinton, S., Green, L., Myerson, J., Wu, J., Ruggeri, K., … Rosenbaum, R. (2022, January 28). Short-sighted decision-making by those not vaccinated against COVID-19. https://doi.org/10.31234/osf.io/6uqky
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psyarxiv.com psyarxiv.com
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Kourtesis, Panagiotis, Graham Wilson, and Mario Parra Rodrigues. ‘Factors Influencing Acceptance of Technology across Age: Amid the COVID-19 Pandemic’. PsyArXiv, 4 February 2022. https://doi.org/10.31234/osf.io/tsrk4.
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www.theguardian.com www.theguardian.com
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France-Presse, A. (2022, March 13). China battles worst Covid outbreak for two years as cases double in 24 hours. The Guardian. https://www.theguardian.com/world/2022/mar/13/china-battles-worst-covid-outbreak-for-two-years-as-cases-double-in-24-hours
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Deepti Gurdasani. (2022, January 10). Lots of people dismissing links between COVID-19 and all-cause diabetes. An association that’s been shown in multiple studies- whether this increase is due to more diabetes or SARS2 precipitating diabetic keto-acidosis allowing these to be diagnosed is not known. A brief look👇 [Tweet]. @dgurdasani1. https://twitter.com/dgurdasani1/status/1480546865812840450
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Deepti Gurdasani. (2022, February 8). Exactly this 👇 We never talk about the huge benefits mitigations have had in reducing other respiratory illnesses... Which means deaths from other causes have reduced. Excess deaths are not a good indicator of COVID-19 deaths—Which we should be doing a lot more to prevent! [Tweet]. @dgurdasani1. https://twitter.com/dgurdasani1/status/1491123632349024256
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ReconfigBehSci. (2022, January 20). @timcolbourn @OmicronData I’m sorry but I genuinely do not see how this is a response to what I said about the presuppositions in the ‘delay framing’? This reply is about your views on disease burden, not -as mine is- how choice of terminology implicitly shapes the argument space [Tweet]. @i. https://twitter.com/i/web/status/1484191657318879234
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COVID-19 takes serious toll on heart health—A full year after recovery. (n.d.). Retrieved February 11, 2022, from https://www.science.org/content/article/covid-19-takes-serious-toll-heart-health-full-year-after-recovery
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ReconfigBehSci. (2022, January 20). @timcolbourn @OmicronData As I said before, it’s not the function of this account to argue/advocate covid policies, but I will comment on the shape of the argument. The use of the frame “just delay” here seems hugely prejudicial. We don’t talk that way about flu or other diseases we might get repeatedly [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1484074977964011520
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Mahase, E. (2022). Omicron sub-lineage BA.2 may have “substantial growth advantage,” UKHSA reports. BMJ, 376, o263. https://doi.org/10.1136/bmj.o263
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ReconfigBehSci on Twitter: “RT @AliHMokdad: Vaccine effectiveness against BA.1 and BA.2. After 2 doses it was 9% (7-10%) and 13% (-26-40%) respectively for BA.1 and BA…” / Twitter. (n.d.). Retrieved January 30, 2022, from https://twitter.com/SciBeh/status/1487123660771106821
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James 💙 Neill - 😷 🇪🇺🇮🇪🇬🇧🔶. (2022, January 23). Of 51,141 deaths due to ischaemic heart diseases 32,872 (64.3%) had pre-existing conditions.💔 Do those 33k heart disease deaths not count? Or is an absence of pre-existing conditions only required for Covid deaths...😡⁉️ Source: ONS England 2019 [Tweet]. @jneill. https://twitter.com/jneill/status/1485327886164844546
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Helder Nakaya. (2022, January 14). 75 years of research on human diseases in 1 minute https://t.co/1QtdijRTtJ [Tweet]. @helder_nakaya. https://twitter.com/helder_nakaya/status/1482095277813157888
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•. (n.d.). Even Mild COVID Infections Can Have Lasting Impacts Like ‘Chemo Brain,’ Study Finds. NBC New York. Retrieved 12 January 2022, from https://www.nbcnewyork.com/news/coronavirus/even-mild-covid-infections-can-have-lasting-impacts-like-chemo-brain-study-finds/3489958/
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CDC studies confirm mask-wearing in schools reduces spread of COVID-19. (2021, September 27). New Atlas. https://newatlas.com/health-wellbeing/cdc-mask-mandate-children-schools-coronavirus-effective/
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Kit Yates. (2021, November 26). European centres for disease prevention and control has designated B.1.1.259 as a variant of concern. Fast work. Https://t.co/f6JiWVvjJC [Tweet]. @Kit_Yates_Maths. https://twitter.com/Kit_Yates_Maths/status/1464285136137170947
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Dr Ellie Murray, ScD. (2021, October 2). Everyone keeps talking about covid becoming endemic, but as I listen to the conversation, it’s becoming more & more clear to me that very few of you know what “endemic” means. So here’s a thread on how pandemics end. Https://t.co/uuYinUcynb [Tweet]. @EpiEllie. https://twitter.com/EpiEllie/status/1444088804961304581
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Cerebrospinal fluid and plasma biomarkers, as well as amyloid imaging markers, can offer information about neuropathological symptoms of AD, when no evidence markers for hippocampal volume loss can be accurately exported from MRI scanning [49]
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JITSUVAX. (2021, November 8). 🤰UPDATE: The @SciBeh and @jitsuvax team has created a new page ‘COVID-19 Vaccines and Pregnancy’. Learn more about the risk of the disease, the safety of vaccination, breast-feeding and common myths about fertility https://c19vax.scibeh.org/pages/pregnancy https://t.co/g6BFn7DHPD [Tweet]. @jitsuvax. https://twitter.com/jitsuvax/status/1457654003467182084
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- Oct 2021
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Prof. Akiko Iwasaki. (2021, September 23). Thankfully, we have not seen any evidence of antibody-dependent enhancement of infection or disease by any COVID vaccines to date. Vaccine are not making infections worse, and are very effective in preventing disease. [Tweet]. @VirusesImmunity. https://twitter.com/VirusesImmunity/status/1441074260534075392
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