9 Matching Annotations
  1. Jan 2020
    1. Interactions between Mycobacterium tuberculosis (Mtb) and human (players) are often included in the Mtb’s strategies to invade host responses, to replicate and persist within the host,

      Does the M.Tb have knowledge of the host responses or is it merely adapting bet hedging strategies (a mix of multiple strategies across population) and whatever survived is what we see.

      This will have major implications in treating the problem in a game theoretic fashion

  2. Jul 2019
    1. “It is very important to have the research done here because at the end of the day, Ebola is our problem,” says Sabue Mulangu, an infectious-disease researcher at the INRB.

      This line of thinking is necessary in parts of world like India where infectious disease outbreaks are commonplace.

    1. Infections during pregnancy are associated with low birth weights, congenital birth defects, pregnancy complications, and miscarriages(1)

      Like this. And type whatever I want.

  3. Mar 2019
    1. Infections are a common cause of death and an even more common cause of morbidity in patients with a wide variety of neoplasms.

      It's interesting to learn this about infections.

  4. Jan 2019
  5. Nov 2017
    1. Toxoplasmosis is caused by the obligate intracellular parasite, Toxoplasma gondii. Its life cycle consists of 3 forms, including an oocyst, a tissue cyst, and an active (proliferative) form.

      See also: CDC- Toxoplasmosis


      Source of Infection in humans:

      1. Eating under cooked meat of animals harboring tissue cysts
      2. Consuming food or water contaminated with cat feces or by contaminated environmental samples (such as fecal-contaminated soil or changing the litter box of a pet cat)
      3. Blood transfusion or organ transplantation
      4. Transplacentally from mother to fetus

      Sources of T. gondi infection

      Life cycle of T. gondi

    2. The acronym TORCH was initially proposed by Andres Nahmias in 1971 to represent 4 congenital infections with a similar clinical presentation, including a rash and ocular findings in neonates: toxoplasmosis, rubella, cytomegalovirus (CMV), and herpes simplex virus (HSV). Over the next few years, the acronym was changed to TORCHES to include syphilis.

      The “other” category now includes:

      *Lymphocytic Choriomeningitis virus (LCMV)

      *Parvovirus B19


      *Varicella-zoster virus

      *Epstein-Barr virus

      *Human immunodeficiency virus (HIV)

      *West Nile virus, and

      • Zika virus (ZIKV).

      The most complex events in embryogenesis involving the sensory organs take place during the first few weeks of pregnancy, making the eyes and ears particularly vulnerable. The fetus does not have the immunologic mechanisms needed to eliminate the organism, leading to immunologic tolerance and chronic infection.

      The most common eye finding of congenital infections is a chorioretinal scar. Congenital cataracts, optic nerve atrophy, or hypoplasia may also be found.

  6. Sep 2017
    1. One Test May Spot Cancer, Infections, Diabetes and More

      based on cell free DNA fragments in blood; DNA methylation patterns and fragment length distributions can inform on organ of origin.