221 Matching Annotations
  1. Last 7 days
    1. Townsend, L., Dyer, A. H., Naughton, A., Kiersey, R., Holden, D., Gardiner, M., Dowds, J., O’Brien, K., Bannan, C., Nadarajan, P., Dunne, J., Martin-Loeches, I., Fallon, P. G., Bergin, C., O’Farrelly, C., Cheallaigh, C. N., Bourke, N. M., & Conlon, N. (2021). Longitudinal Analysis of COVID-19 Patients Shows Age-Associated T Cell Changes Independent of Ongoing Ill-Health. Frontiers in Immunology, 12. https://www.frontiersin.org/article/10.3389/fimmu.2021.676932

  2. Jan 2022
  3. Dec 2021
  4. Nov 2021
  5. Oct 2021
  6. Sep 2021
    1. from the analog age to the digital age

      So what is the exact definition of digital age? When can we say that we live in a digital age?

    1. John Burn-Murdoch. (2021, August 23). NEW: in the last couple of weeks there have a lot of new studies out assessing vaccine efficacy, many of which have touched on the question of waning immunity. Unsurprisingly, these have prompted a lot of questions. Time for a thread to summarise what we do and don’t know: [Tweet]. @jburnmurdoch. https://twitter.com/jburnmurdoch/status/1429878189011111936

    1. Liu, W., Russell, R. M., Bibollet-Ruche, F., Skelly, A. N., Sherrill-Mix, S., Freeman, D. A., Stoltz, R., Lindemuth, E., Lee, F.-H., Sterrett, S., Bar, K. J., Erdmann, N., Gouma, S., Hensley, S. E., Ketas, T., Cupo, A., Cruz Portillo, V. M., Moore, J. P., Bieniasz, P. D., … Hahn, B. H. (2021). Predictors of Nonseroconversion after SARS-CoV-2 Infection. Emerging Infectious Diseases, 27(9), 2454–2458. https://doi.org/10.3201/eid2709.211042

  7. Aug 2021
    1. Dr Greg Kelly. (2021, July 2). As a pediatrician I’m going on record saying that allowing kids to be freely infected with a novel disease that has unknown long term consequences is the worst idea of 2021 despite being a pretty crowded field so far #COVID19 [Tweet]. @drgregkelly. https://twitter.com/drgregkelly/status/1411083905034117120

    1. Carl T. Bergstrom. (2021, August 18). 1. There has been lots of talk about recent data from Israel that seem to suggest a decline in vaccine efficacy against severe disease due to Delta, waning protection, or both. This may have even been a motivation for Biden’s announcement that the US would be adopting boosters. [Tweet]. @CT_Bergstrom. https://twitter.com/CT_Bergstrom/status/1427767356600688646

    1. Marc Lipsitch. (2021, July 20). At the risk of boiling down too much and certainly losing some detail, one way to summarize this wonderful thread is that when we think about vaccine effectiveness, we should think of 4 key variables: 1 which vaccine, 2 age of the person, 3 how long after vax, 4 vs what outcome. [Tweet]. @mlipsitch. https://twitter.com/mlipsitch/status/1417595538632060931

    1. (((Howard Forman))). (2021, July 26). ‘Among those aged 60-plus, early vaccinators are twice as likely to get infected. For those aged 40-59 early vaccinators are 2.1 times more vulnerable, and among under 39s they are 1.6 more likely to catch the coronavirus.’ https://timesofisrael.com/hmo-those-who-inoculated-early-twice-as-likely-to-catch-covid-as-later-adopters/ [Tweet]. @thehowie. https://twitter.com/thehowie/status/1419647827458789383

  8. Jul 2021
    1. Collier, D. A., Ferreira, I. A. T. M., Kotagiri, P., Datir, R., Lim, E., Touizer, E., Meng, B., Abdullahi, A., Elmer, A., Kingston, N., Graves, B., Gresley, E. L., Caputo, D., Bergamaschi, L., Smith, K. G. C., Bradley, J. R., Ceron-Gutierrez, L., Cortes-Acevedo, P., Barcenas-Morales, G., … Gupta, R. K. (2021). Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2. Nature, 1–9. https://doi.org/10.1038/s41586-021-03739-1

  9. Jun 2021
    1. Helen McArdle on Twitter: “The good news: An astonishing 98.2% of over-60s in Scotland are now fully vaccinated. That’s an amazing uptake. It doesn’t mean they are 100% protected of course (and especially not when case rates are high) but their risk of hospitalisation/death is cut by over 90% https://t.co/DzAxkpLvcR” / Twitter. (n.d.). Retrieved June 30, 2021, from https://twitter.com/HMcArdleHT/status/1409821893557768195

  10. May 2021
    1. Prof. Christina Pagel. (2021, April 15). THREAD on VACCINATION & EQUITY in ENGLAND: I know I’ve tweeted about this before, but now we can look at how gaps by deprivation and ethnicity change with age groups and what that might mean... TLDR: widening gaps but access and communication will be key I suspect 1/5 [Tweet]. @chrischirp. https://twitter.com/chrischirp/status/1382725119773134848

  11. Apr 2021
  12. Mar 2021
    1. Theodore Roosevelt—who denounced the “unfair money-getting” that created a “small class of enormously wealthy and economically powerful men, whose chief object is to hold and increase their power”—rewrote the rules. He broke up monopolies to make the economy more fair, returning power to small businesses and entrepreneurs. He enacted protections for working people. And he created the national parks, public spaces for all to enjoy.

      We could definitely use another round of this now. Where is the end of our current gilded age?

    1. Legally, for humans, (at least in the UK since 1970) adults are people aged 18 or older.

      This is incorrect. There are different ages for different purposes and varies by countries in the UK. For example, in England and Wales, those 16 to 18 can marry, but only with parental consent. In Scotland, parental consent is not required for this age group.

    1. O’Driscoll, M., Santos, G. R. D., Wang, L., Cummings, D. A. T., Azman, A. S., Paireau, J., Fontanet, A., Cauchemez, S., & Salje, H. (2020). Age-specific mortality and immunity patterns of SARS-CoV-2 infection in 45 countries. MedRxiv, 2020.08.24.20180851. https://doi.org/10.1101/2020.08.24.20180851

    1. Grint, D. J., Wing, K., Williamson, E., McDonald, H. I., Bhaskaran, K., Evans, D., Evans, S. J., Walker, A. J., Hickman, G., Nightingale, E., Schultze, A., Rentsch, C. T., Bates, C., Cockburn, J., Curtis, H. J., Morton, C. E., Bacon, S., Davy, S., Wong, A. Y., … Eggo, R. M. (2021). Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England. MedRxiv, 2021.03.04.21252528. https://doi.org/10.1101/2021.03.04.21252528

    1. Gupta, R. K., Marks, M., Samuels, T. H. A., Luintel, A., Rampling, T., Chowdhury, H., Quartagno, M., Nair, A., Lipman, M., Abubakar, I., Smeden, M. van, Wong, W. K., Williams, B., & Noursadeghi, M. (2020). Systematic evaluation and external validation of 22 prognostic models among hospitalised adults with COVID-19: An observational cohort study. MedRxiv, 2020.07.24.20149815. https://doi.org/10.1101/2020.07.24.20149815

  13. Feb 2021
    1. Pastor-Barriuso, R., Pérez-Gómez, B., Hernán, M. A., Pérez-Olmeda, M., Yotti, R., Oteo-Iglesias, J., Sanmartín, J. L., León-Gómez, I., Fernández-García, A., Fernández-Navarro, P., Cruz, I., Martín, M., Delgado-Sanz, C., Larrea, N. F. de, Paniagua, J. L., Muñoz-Montalvo, J. F., Blanco, F., Larrauri, A., & Pollán, M. (2020). Infection fatality risk for SARS-CoV-2 in community dwelling population of Spain: Nationwide seroepidemiological study. BMJ, 371, m4509. https://doi.org/10.1136/bmj.m4509

    1. Enquittant leurs parents, ces jeunes passent par unepériode transitionnelle au cours de laquelle ils mul-tiplient les expériences dans une phase de construc-tion de soi.

      les jeunes de la population majoritaire et ceux originaires du sud connaissent une phase de transitoire où ils peuvent expérimenter se construire hors du domicile parental . Les étapes d'entrée dans l'âge adulte sont moins préétablies. Ce qui s'explique par le fait que les parents des jeunes originaires de l'Europe du Sud sont arrivés plus jeunes . en France et ils sont moins victimes du racisme et des discriminations Les jeunes d'origine maghrébines connaissent un parcours plus linéaire et resserré entre l'union et le premier enfant.

    2. On peut dès lors présumer que lesdifficultés rencontrées au cours de la scolaritéauront des effets durables sur les âges et les moda-lités de franchissement des autres étapes de cetteentrée dans la vie adulte.

      hypothèse Les diplômes étant déterminant dans l'insertion professionnel dans le système français, on peut penser que le parcours scolaire difficile des jeunes issus de l'immigration va impacter la manière d'entrer dans l'âge adulte et les différente articulations de celui-ci.

  14. Jan 2021
    1. From morn to night

      We started the poem at the beginning of the day and now end at night. Not only does this show the "circle motif" in this poem - what I mean is how "all things come to a close" and then restart anew - but it also parallels the journey of the youth, from being naive and blissful to being to falling victim to that naivety and becoming unaware of their fictitious bliss in the unknown; the journey leads to isolation from reality.

    2. Doubt is fled=stuck to their opinions

      Doubt is fled seems very much like a point on the youths lack of internal questioning. They do not think there is room for doubt, as they must be right - a point made from their lack of understanding the nuance of truth and reality.

    3. delight=bliss in not understanding?

      Does this mean that there is delight in not understanding truth? It is the youths who are delighted, relating to their lack of experience.

      p.s This poem is taken from Selected Poetry and Prose of Blake (section Songs of Experience)

    4. opening morn=sunrise

      We start the poem at the beginning of the day, juxtaposing the youth that come hither. Just as the day begins, so do the youth with their lives.

    5. truth new born

      The youth are at the beginning of their lives, and so the image of truth (reality as it is perceived universally) is also in its beginning stages, not fully developed nor fully understood by the youth.

  15. Dec 2020
  16. Nov 2020
  17. icla2020b.jonreeve.com icla2020b.jonreeve.com
    1. there were some of Lord Lytton’s works which boys couldn’t read.

      So I was super curious what Lord Lytton had written that would be considered too much for young boys. I couldn't find anything "controversial" by some light googling, but it's clear that the old man means this in a very very creepy way, and that's he's trying to insinuate that the narrator then must be "mature" and "not like other boys" for having read it. Something fun about Lord Lytton is that there's the Bulwer-Lytton Fiction Contest every year which looks for the worst opening line for a book every year. It's a lot of fun to check out.

    1. too old for the spring

      Spring is usually associated with birth, life, and youth, so it makes sense that Mr. Neave being old would make him unfit for Spring. But on the other hand, I've never heard someone complain about being too old for Spring. I've heard my grandmother complain about winter or summer, but spring is a pretty nice and easy season for the elderly.

  18. Oct 2020
    1. Designing Social Media for Informal Learning and Knowledge Maturing in the Digital Workplace

      Ravenscroft, A., Schmidt, A., Cook, J., & Bradley, C. (2012). Designing Social Media for Informal Learning and Knowledge Maturing in the Digital Workplace. Journal of Computer Assisted Learning, 28(3), 235–249.

      https://search.ebscohost.com/login.aspx?direct=true&AuthType=shib&db=eric&AN=EJ966042&site=eds-live&scope=site&custid=uphoenix

      This paper presents an original approach to designing social media that support informal learning in the digital workplace. It adapts design-based research to take into account the embeddedness of interactions within digitally mediated work-based contexts. The approach is demonstrated through the design, implementation, and evaluation of software tools supporting a particular type of informal learning called "knowledge maturing". The paper: introduces and presents the rationale for, and concept of, knowledge maturing; presents a new design methodology for developing social media that support informal learning and knowledge maturing; focuses on one prototype, for "people tagging for organisational development", that was produced by the methodology (and concisely describes two others); presen