- Nov 2022
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web.archive.org web.archive.org
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web.archive.org web.archive.org
- Aug 2022
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tracydurnell.com tracydurnell.com
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mutational meltdown
Mutational meltdown happens in a population of animals if their number is so low that negative mutations and deletions in their DNA accumulate.
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- Apr 2022
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twitter.com twitter.com
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Dr Emma Hodcroft. (2021, May 2). 🗓️https://t.co/wVE7ubYBoy is updated🗓️, with some cool new additions: - B.1.617.1/2 are added as 20A/S:154K & 20A/S:478K 🎉—Beautiful new name table 📑🍾—Mutation list displayed in full as a ‘side-sausage’🌭 Let’s take a tour... 😁 1/7 [Tweet]. @firefoxx66. https://twitter.com/firefoxx66/status/1388921325411053569
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- Feb 2022
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www.nature.com www.nature.com
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Mallapaty, Smriti. ‘Where Did Omicron Come from? Three Key Theories’. Nature 602, no. 7895 (28 January 2022): 26–28. https://doi.org/10.1038/d41586-022-00215-2.
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- Mar 2021
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www.theguardian.com www.theguardian.com
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the Guardian. ‘How a String of Failures by the British Government Helped Covid-19 to Mutate | Anthony Costello’, 22 December 2020. http://www.theguardian.com/commentisfree/2020/dec/22/uk-government-blamed-covid-19-mutation-occur.
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twitter.com twitter.com
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ReconfigBehSci on Twitter: ‘RT @AdamJKucharski: Summary of NERVTAG view on new SARS-CoV-2 variant, from 18 Dec (full document here: Https://t.co/yll9beVI9A) https://t.…’ / Twitter. (n.d.). Retrieved 2 March 2021, from https://twitter.com/SciBeh/status/1341034652082036739
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- Apr 2017
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while those that had been moved to 25 degrees had largely lost the methylation tags. Importantly, they still maintained this reduced histone methylation when moved back to the cooler temperature, suggesting that it is playing an important role in locking the memory into the transgenes.
Could it be that the genetic background (or importantly surrounding environment or cross talk among cells) in the first generation that were exposed to 25 C temp might have changed, and conditioned subsequent generations?
After 14 generations, secondary changes in the propoagated genetic makeup (including cross talk) could have reverted phenotype and reset histone marks to repress gene expression.
See if how often c.elegans mutate or show CN changes, i.e., background vs stress induced by temp changes?
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