- Jan 2021
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www-nature-com.ezproxy.rice.edu www-nature-com.ezproxy.rice.edu
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we developed a vastly improved INTEGRATE system that uses streamlined expression vectors to direct highly accurate insertions at ~100% efficiency effectively in a single orientation, independent of the cargo size, without requiring selection markers
Efficiency sounds too exciting to not try!
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- Aug 2020
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www.medrxiv.org www.medrxiv.org
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Ferretti, A. P., Kula, T., Wang, Y., Nguyen, D. M., Weinheimer, A., Dunlap, G. S., Xu, Q., Nabilsi, N., Perullo, C. R., Cristofaro, A. W., Whitton, H. J., Virbasius, A., Olivier, K. J., Baiamonte, L. B., Alistar, A. T., Whitman, E. D., Bertino, S. A., Chattopadhyay, S., & MacBeath, G. (2020). COVID-19 Patients Form Memory CD8+ T Cells that Recognize a Small Set of Shared Immunodominant Epitopes in SARS-CoV-2. MedRxiv, 2020.07.24.20161653. https://doi.org/10.1101/2020.07.24.20161653
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www.biorxiv.org www.biorxiv.org
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Guo, L., Boocock, J., Tome, J. M., Chandrasekaran, S., Hilt, E. E., Zhang, Y., Sathe, L., Li, X., Luo, C., Kosuri, S., Shendure, J. A., Arboleda, V. A., Flint, J., Eskin, E., Garner, O. B., Yang, S., Bloom, J. S., Kruglyak, L., & Yin, Y. (2020). Rapid cost-effective viral genome sequencing by V-seq. BioRxiv, 2020.08.15.252510. https://doi.org/10.1101/2020.08.15.252510
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www.youtube.com www.youtube.com
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Science Facebook Live: Understanding SARS-CoV-2 structure informs vaccine design, clinical trials. (2020, March 20). https://www.youtube.com/watch?v=nOzEx3OpKe8
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www.biorxiv.org www.biorxiv.org
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Qu, J., Cai, Z., Liu, Y., Duan, X., Han, S., Zhu, Y., Jiang, Z., Zhang, Y., Zhuo, C., Liu, Y., Liu, Y., Liu, L., & Yang, L. (2020). Persistent bacterial coinfection of a COVID-19 patient caused by a genetically adapted Pseudomonas aeruginosa chronic colonizer. BioRxiv, 2020.08.05.238998. https://doi.org/10.1101/2020.08.05.238998
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www.medrxiv.org www.medrxiv.org
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Lednicky, J. A., Lauzardo, M., Fan, Z. H., Jutla, A. S., Tilly, T. B., Gangwar, M., Usmani, M., Shankar, S. N., Mohamed, K., Eiguren-Fernandez, A., Stephenson, C. J., Alam, M. M., Elbadry, M. A., Loeb, J. C., Subramaniam, K., Waltzek, T. B., Cherabuddi, K., Morris, J. G., & Wu, C.-Y. (2020). Viable SARS-CoV-2 in the air of a hospital room with COVID-19 patients. MedRxiv, 2020.08.03.20167395. https://doi.org/10.1101/2020.08.03.20167395
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www.youtube.com www.youtube.comYouTube1
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LucyinLockdown: Viruses, Pandemics and Lessons Learnt with Dr Jane Greatorex—YouTube. (2020, June 18). https://youtu.be/5U1go5hyen8
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- Jul 2020
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www.nationalgeographic.com www.nationalgeographic.com
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How coronavirus mutations can track its spread—And disprove conspiracies. (2020, March 26). Science. https://www.nationalgeographic.com/science/2020/03/how-coronavirus-mutations-can-track-its-spread-and-disprove-conspiracies/
Tags
- transmission
- is:preprint
- origin
- research
- lang:en
- genome
- sequencing
- conspiracy theory
- genetics
- COVID-19
- misinformation
- tracking
- mutation
Annotators
URL
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www.cell.com www.cell.com
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How scientists know COVID-19 is way deadlier than the flu. (2020, July 2). Science. https://www.nationalgeographic.com/science/2020/07/coronavirus-deadlier-than-many-believed-infection-fatality-rate-cvd/
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www.thelancet.com www.thelancet.com
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Behrmann, Ole, and Martin Spiegel. ‘COVID-19: From Rapid Genome Sequencing to Fast Decisions’. The Lancet Infectious Diseases 0, no. 0 (14 July 2020). https://doi.org/10.1016/S1473-3099(20)30580-6.
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- Jun 2020
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threader.app threader.app
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Balloux, F. (2020, May 22) A thread written by @BallouxFrancois. Threader. https://threader.app/thread/1263745877702737920
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- May 2020
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www.nature.com www.nature.com
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Andersen, K.G., Rambaut, A., Lipkin, W.I. et al. The proximal origin of SARS-CoV-2. Nat Med 26, 450–452 (2020). https://doi.org/10.1038/s41591-020-0820-9
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- Apr 2020
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academic.oup.com academic.oup.com
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"Nala" the female German Shepherd Dog. Nala, or formally “Jonkahra Nala” (Australian Registration #2100398550)
More on Nala in the Vet Candy blog https://www.myvetcandy.com/clinicalupdblog/2020/4/2/first-complete-german-shepherd-dna-offers-new-tool-to-fight-disease
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Findings
Coverage in GenomeWeb https://www.genomeweb.com/scan/german-shepherds-own-sequence#.XoeoXG4o-qA
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- Nov 2017
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www.nature.com www.nature.com
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Two independent modes of chromatin organization revealed by cohesin removal
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Annotators
URL
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- Oct 2017
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www.biostars.org www.biostars.org
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What Tools/Libraries Do You Use To Visualize Genomic Feature Data?
discussion of tools; recently revived
Tags
Annotators
URL
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asciigenome.readthedocs.io asciigenome.readthedocs.io
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ASCIIGenome is a command-line genome browser running from terminal window
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www.sanger.ac.uk www.sanger.ac.uk
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Artemis is a free genome browser and annotation tool that allows visualisation of sequence features, next generation data and the results of analyses within the context of the sequence, and also its six-frame translation
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Annotators
URL
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github.com github.com
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Genome Maps is a modern and high-performance web-based HTML5 genome browser
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Annotators
URL
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- Sep 2017
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www.biorxiv.org www.biorxiv.org
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Major flaws in "Identification of individuals by trait prediction using whole-genome sequencing data"
re Venter study in PNAS, claiming to be able to identify people based on whole genome data
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www.nature.com www.nature.com
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Plot a course through the genome Inspired by Google Maps, a suite of tools is allowing researchers to chart the complex conformations of chromosomes.
mentioned tools are focused on (capture) Hi-C data
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- Jul 2017
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www.napoleome.ch www.napoleome.ch
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Napoleon oak genome sequencing project web site: example of public engagement in tree genomics
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Annotators
URL
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Quercus robur Genome sequencing and assembly
data (not yet live) associated with https://hyp.is/4DerrmIaEeehDPNBqsRcxQ/www.biorxiv.org/content/biorxiv/early/2017/06/13/149203.full.pdf
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Annotators
URL
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- Jun 2017
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molossinus.lab.nig.ac.jp molossinus.lab.nig.ac.jp
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Takada et al. 2013
NIG Mouse Genome Database: JF1 and MSM SNPs; effective genome browser
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Annotators
URL
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- Sep 2016
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software.broadinstitute.org software.broadinstitute.org
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You must quit IGV and restart for this preference to take effect. The genome should appear in the drop-down list.
restart may be insufficient; had to modify prefs.properties in ~/igv (removing old cached genome values) before i could see my genomes
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- Apr 2016
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gigadb.org gigadb.org
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IsPreviousVersionOf doi:10.5524/100148
This paper was studied in a case study that lead to some corrections. See the paper here: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127612
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gigadb.org gigadb.org
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genomically poorly explored
Poorly studied in some part to its very high degree of heterozygosity. You can get some more insight here, where it was nominated as a "top ten genome" http://www.homolog.us/blogs/blog/2015/05/08/top-ten-genomes-ix-pacific-oyster/
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URL
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gigadb.org gigadb.org
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Long Fragment Read technology
See Nature doi:10.1038/nature11236 for more on how LFR works: http://www.nature.com/nature/journal/v487/n7406/full/nature11236.html
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