- Dec 2020
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www.newscientist.com www.newscientist.com
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Lawton. G. (2020) Coronavirus family tree reveals the virus is hardly mutating. New Scientist. Retrieved from: https://www.newscientist.com/article/2254387-coronavirus-family-tree-reveals-the-virus-is-hardly-mutating/?utm_medium=social&utm_campaign=echobox&utm_source=Twitter#Echobox=1600082893
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- Aug 2020
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pubs.acs.org pubs.acs.org
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Zhang, Q., Honko, A., Zhou, J., Gong, H., Downs, S. N., Vasquez, J. H., Fang, R. H., Gao, W., Griffiths, A., & Zhang, L. (2020). Cellular Nanosponges Inhibit SARS-CoV-2 Infectivity. Nano Letters. https://doi.org/10.1021/acs.nanolett.0c02278
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- Jul 2020
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www.biorxiv.org www.biorxiv.org
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Yurkovetskiy, L., Wang, X., Pascal, K. E., Tomkins-Tinch, C., Nyalile, T., Wang, Y., Baum, A., Diehl, W. E., Dauphin, A., Carbone, C., Veinotte, K., Egri, S. B., Schaffner, S. F., Lemieux, J. E., Munro, J., Rafique, A., Barve, A., Sabeti, P. C., Kyratsous, C. A., … Luban, J. (2020). Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant. BioRxiv, 2020.07.04.187757. https://doi.org/10.1101/2020.07.04.187757
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www.houstonchronicle.com www.houstonchronicle.com
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Ackerman, T. (2020, July 4). Evidence growing that Houston’s main coronavirus strain is more contagious than original. HoustonChronicle.Com. https://www.houstonchronicle.com/news/houston-texas/houston/article/coronavirus-evidence-growing-houston-strain-mutant-15386157.php
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- transmission
- contagiousness
- Houston
- epidemiology
- is:news
- risk
- fitness advantage
- lang:en
- USA
- COVID-19
- strain
- mutation
- research
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www.nationalgeographic.com www.nationalgeographic.com
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How coronavirus mutations can track its spread—And disprove conspiracies. (2020, March 26). Science. https://www.nationalgeographic.com/science/2020/03/how-coronavirus-mutations-can-track-its-spread-and-disprove-conspiracies/
Tags
- sequencing
- transmission
- genome
- misinformation
- genetics
- tracking
- origin
- lang:en
- COVID-19
- conspiracy theory
- mutation
- research
- is:preprint
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www.scientificamerican.com www.scientificamerican.com
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Kwon, K. (n.d.). Second Coronavirus Strain May Be More Infectious—but Some Scientists Are Skeptical. Scientific American. Retrieved July 17, 2020, from https://www.scientificamerican.com/article/second-coronavirus-strain-may-be-more-infectious-but-some-scientists-are-skeptical/
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www.biorxiv.org www.biorxiv.org
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Corbett, K. S., Edwards, D., Leist, S. R., Abiona, O. M., Boyoglu-Barnum, S., Gillespie, R. A., Himansu, S., Schäfer, A., Ziwawo, C. T., DiPiazza, A. T., Dinnon, K. H., Elbashir, S. M., Shaw, C. A., Woods, A., Fritch, E. J., Martinez, D. R., Bock, K. W., Minai, M., Nagata, B. M., … Graham, B. S. (2020). SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness. BioRxiv, 2020.06.11.145920. https://doi.org/10.1101/2020.06.11.145920
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www.biorxiv.org www.biorxiv.org
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Zhang, L., Jackson, C. B., Mou, H., Ojha, A., Rangarajan, E. S., Izard, T., Farzan, M., & Choe, H. (2020). The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity. BioRxiv, 2020.06.12.148726. https://doi.org/10.1101/2020.06.12.148726
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www.biorxiv.org www.biorxiv.org
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Sapoval, N., Mahmoud, M., Jochum, M. D., Liu, Y., Elworth, R. A. L., Wang, Q., Albin, D., Ogilvie, H., Lee, M. D., Villapol, S., Hernandez, K., Berry, I. M., Foox, J., Beheshti, A., Ternus, K., Aagaard, K. M., Posada, D., Mason, C., Sedlazeck, F. J., & Treangen, T. J. (2020). Hidden genomic diversity of SARS-CoV-2: Implications for qRT-PCR diagnostics and transmission. BioRxiv, 2020.07.02.184481. https://doi.org/10.1101/2020.07.02.184481
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- Jun 2020
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Starr, T. N., Greaney, A. J., Hilton, S. K., Crawford, K. H., Navarro, M. J., Bowen, J. E., Tortorici, M. A., Walls, A. C., Veesler, D., & Bloom, J. D. (2020). Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding [Preprint]. Microbiology. https://doi.org/10.1101/2020.06.17.157982
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twitter.com twitter.com
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Bloom Lab. (2020, June 18). "We've experimentally measured how all amino-acid mutations to the #SARSCoV2 spike RBD affect ACE2 binding and expression of folded protein in a deep mutational scanning study led by @tylernstarr & Allie Greaney:https://biorxiv.org/content/10.1101/2020.06.17.157982v1 Why is this important? (1/n)" Twitter. https://twitter.com/jbloom_lab/status/1273468539484213248
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threader.app threader.app
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Balloux, F. (2020, May 22) A thread written by @BallouxFrancois. Threader. https://threader.app/thread/1263745877702737920
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- May 2020
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www.theguardian.com www.theguardian.com
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Davis, N. (2020, May 26). Research reveals gene role in both dementia and severe Covid-19. The Guardian. https://www.theguardian.com/world/2020/may/26/research-reveals-gene-role-in-both-dementia-and-severe-covid-19
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www.nature.com www.nature.com
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Andersen, K.G., Rambaut, A., Lipkin, W.I. et al. The proximal origin of SARS-CoV-2. Nat Med 26, 450–452 (2020). https://doi.org/10.1038/s41591-020-0820-9
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www.scientificamerican.com www.scientificamerican.com
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Krzywinski, M. F., Martin. (n.d.). Virus Mutations Reveal How COVID-19 Really Spread. Scientific American. Retrieved May 6, 2020, from https://www.scientificamerican.com/article/virus-mutations-reveal-how-covid-19-really-spread1/
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- May 2018
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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SRSF1-Regulated Alternative Splicing in Breast Cancer
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www.cell.com www.cell.com
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Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types
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- Nov 2017
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gmt.genome.wustl.edu gmt.genome.wustl.edu
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SomaticSniper
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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tier 1 contains all changes in the amino acid coding regions of annotated exons, consensus splice-site regions, and RNA genes (including microRNA genes). Tier 2 contains changes in highly conserved regions of the genome or regions that have regulatory potential. Tier 3 contains mutations in the nonrepetitive part of the genome that does not meet tier 2 criteria, and tier 4 contains mutations in the remainder of the genome
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onlinelibrary.wiley.com onlinelibrary.wiley.com
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The background puzzle: how identical mutations in the same gene lead to different disease symptoms
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- Sep 2017
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www.nature.com www.nature.com
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Parental influence on human germline de novo mutations in 1,548 trios from Iceland
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