8 Matching Annotations
  1. Aug 2022
  2. www.nature.com www.nature.com
    Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity
    1
    1. jackiekrauss 29 Aug 2022

      Meng, B., Abdullahi, A., Ferreira, I. A. T. M., Goonawardane, N., Saito, A., Kimura, I., Yamasoba, D., Gerber, P. P., Fatihi, S., Rathore, S., Zepeda, S. K., Papa, G., Kemp, S. A., Ikeda, T., Toyoda, M., Tan, T. S., Kuramochi, J., Mitsunaga, S., Ueno, T., … Gupta, R. K. (2022). Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity. Nature, 1–1. https://doi.org/10.1038/s41586-022-04474-x

      is:article lang:en COVID-19 Omicron tropism fusogenicity spike mutation ACE2 neutralization antiviral drug efficacy lower replication Delta variant TMPRSS2
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    nature.com/articles/s41586-022-04474-x
  3. Feb 2022
  4. www.ft.com www.ft.com
    Merck struggles to win European approval for Covid antiviral pill
    1
    1. lucyparfitt16 17 Feb 2022

      Mancini, D. P., & Smyth, J. (2022, February 16). Merck struggles to win European approval for Covid-19 antiviral pill. Financial Times. https://www.ft.com/content/2cf0b6cc-b07b-4ff9-a833-42eb1798a576

      is:news lang:en Europe approval Merck COVID-19 antiviral pill EMA marketing authorization data molnupiravir drug treatment mortality hospitalization efficacy Pfizer Paxlovid medicine clinical trials
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    ft.com/content/2cf0b6cc-b07b-4ff9-a833-42eb1798a576
  5. assets.publishing.service.gov.uk assets.publishing.service.gov.uk
    S1513 Viral Evolution Scenarios.pdf
    1
    1. lucyparfitt16 14 Feb 2022

      Academics: Viral Evolution Scenarios, 10 February 2022. (n.d.). GOV.UK. Retrieved February 14, 2022, from https://www.gov.uk/government/publications/academics-viral-evolution-scenarios-10-february-2022

      is:report lang:en COVID-19 UK scenario variant prediction viral evolution immunity transmissibility vaccination infection vaccine immune escape waning immunity protection heterogeneity antigenic escape severity antiviral drug resistance surveillance therapeutic testing vaccine efficacy
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    assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1054323/S1513_Viral_Evolution_Scenarios.pdf
  6. Nov 2021
  7. www.science.org www.science.org
    Antiviral pills could change pandemic’s course
    1
    1. lucyparfitt16 12 Nov 2021

      Couzin-Frankel, J. (2021). Antiviral pills could change pandemic’s course. Science, 374(6569), 799–800. https://doi.org/10.1126/science.acx9605

      is:article lang:en COVID-19 antiviral pill treatment clinical trials research drug development breakthrough infection vaccine safety net funding biology resistance medication virology
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    science.org/doi/10.1126/science.acx9605
  8. Aug 2020
  9. www.nature.com www.nature.com
    Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2
    1
    1. ErikStuchly 09 Aug 2020

      Hoffmann, M., Mösbauer, K., Hofmann-Winkler, H., Kaul, A., Kleine-Weber, H., Krüger, N., Gassen, N. C., Müller, M. A., Drosten, C., & Pöhlmann, S. (2020). Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2. Nature, 1–5. https://doi.org/10.1038/s41586-020-2575-3

      is:preprint lang:en COVID-19 chloroquine infection prevention efficacy lung cell antiviral intervention drug protection
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    nature.com/articles/s41586-020-2575-3
  10. Jun 2020
  11. www.theatlantic.com www.theatlantic.com
    The Best Hopes for a Coronavirus Drug
    1
    1. edampf 10 Jun 2020

      Zhang, S. (2020, April 8). The Best Hopes for a Coronavirus Drug. The Atlantic. https://www.theatlantic.com/science/archive/2020/04/what-coronavirus-drug-will-look-like/609661/

      is:webpage lang:en COVID-19 drug pharmaceuticals protein immune system replication biomedical antiviral cytokine storm
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    theatlantic.com/science/archive/2020/04/what-coronavirus-drug-will-look-like/609661/
  12. May 2020
  13. www.thelancet.com www.thelancet.com
    Testing COVID-19 therapies to prevent progression of mild disease
    1
    1. Marlene_Wulf 07 May 2020

      Lipsitch, M., Perlman, S., & Waldor, M. K. (2020). Testing COVID-19 therapies to prevent progression of mild disease. The Lancet Infectious Diseases, 0(0). https://doi.org/10.1016/S1473-3099(20)30372-8

      is:article lang:en COVID-19 testing therapy progression disease influenza antiviral drug placebo symptom treatment oseltamivir
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    thelancet.com/journals/laninf/article/PIIS1473-3099(20)30372-8/fulltext
  14. Apr 2020
  15. www.thelancet.com www.thelancet.com
    Flooded by the torrent: the COVID-19 drug pipeline
    1
    1. edampf 24 Apr 2020

      Mullard, A. (2020). Flooded by the torrent: The COVID-19 drug pipeline. The Lancet, 395(10232), 1245–1246. https://doi.org/10.1016/S0140-6736(20)30894-1

      is:article COVID-19 lang:en drug treatment trial research pharmaceutical therapy healthcare clinical WHO China Gilead data collection antiviral antibody immune system infection
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    thelancet.com/journals/lancet/article/PIIS0140-6736(20)30894-1/fulltext