We could read this together as a group, and do some thinking prior to the discussion, or at least even read what other people are thinking.

James Ward on Twitter. (n.d.). Twitter. Retrieved April 21, 2022, from https://twitter.com/JamesWard73/status/1470680953643319305

Morris, J. (2021, August 17). Israeli data: How can efficacy vs. severe disease be strong when 60% of hospitalized are vaccinated? Covid Data Science. https://www.covid-datascience.com/post/israeli-data-how-can-efficacy-vs-severe-disease-be-strong-when-60-of-hospitalized-are-vaccinated

Carl T. Bergstrom. (2021, August 18). 1. There has been lots of talk about recent data from Israel that seem to suggest a decline in vaccine efficacy against severe disease due to Delta, waning protection, or both. This may have even been a motivation for Biden’s announcement that the US would be adopting boosters. [Tweet]. @CT_Bergstrom. https://twitter.com/CT_Bergstrom/status/1427767356600688646

Hilda Bastian, PhD. (2021, February 6). Unofficial unnamed AstraZeneca insider says they are doing the interim analysis for the US trial of the Oxford vaccine. AstraZeneca spokesperson says 4-6 weeks till data release. Https://t.co/VUHgbHN02d One is wrong? Or they’ll release only when have FDA minimum follow-up? Https://t.co/LgjfX8AIti [Tweet]. @hildabast. https://twitter.com/hildabast/status/1357862227106095105

Dr Ellie Murray, ScD. (2021, July 6). Also, see👇🏼 [Tweet]. @EpiEllie. https://twitter.com/EpiEllie/status/1412249702460968967

(((Howard Forman))). (2021, June 28). There are few more compelling graphics to demonstrate how effective vaccines are: 80+% reduction in hospital admissions for the group most vaccinated. <40% reduction in admissions for the group least likely to be vaccinated. [Tweet]. @thehowie. https://twitter.com/thehowie/status/1409492774009847810

Prof. Christina Pagel. (2021, May 23). LONG THREAD on B.1.617.2 & latest PHE data covering: 1) latest tech report on B.1.617.2 (aka ‘India’ variant) 2) vaccine efficacy against B.1.617.2 3) consequences for roadmap 4) avoidability... Or not. [Tweet]. @chrischirp. https://twitter.com/chrischirp/status/1396574267349872644

Marc Lipsitch. (2021, July 20). At the risk of boiling down too much and certainly losing some detail, one way to summarize this wonderful thread is that when we think about vaccine effectiveness, we should think of 4 key variables: 1 which vaccine, 2 age of the person, 3 how long after vax, 4 vs what outcome. [Tweet]. @mlipsitch. https://twitter.com/mlipsitch/status/1417595538632060931

Just 1 per cent of eligible Canberrans are unvaccinated as the capital becomes one of world’s most-vaccinated cities. (2021, December 30). ABC News. https://www.abc.net.au/news/2021-12-31/covid-canberras-unvaccinated-1-per-cent-in-a-highly-vaxxed-city/100642468

CDC. (2022, February 4). A new @CDCMMWR study shows that people who reported always wearing masks or respirators in indoor public settings in California were less likely to test positive for #COVID19 compared with those who reported not wearing a face covering. Learn more. Http://bit.ly/MMWR7106 https://t.co/6UJ9cs60NK [Tweet]. @CDCgov. https://twitter.com/CDCgov/status/1489675180242870278

ReconfigBehSci. (2021, July 19). this is how the failure to understand what efficacy means and how it relates to outcomes will be seized on over and over again. Cookie cutter fallacies require cookie cutter clarification by machine tools to be combatted effectively (at least at current levels of moderation) [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1417164191664730112

Eran Segal. (2021, August 17). Israel data showing the decay of vaccine efficacy over time. Y-axis is cases per 1000 from July 7 to Aug 10, for unvaccinated, and for people vaccinated at different times Cases are higher in those vaxed earlier Despite world-data caveats, this seems quite compelling https://t.co/5aNz48AC8F [Tweet]. @segal_eran. https://twitter.com/segal_eran/status/1427696623988117505

CNN, A. S. (n.d.). Pfizer begins Phase 2 and 3 trial of Covid-19 antiviral Paxlovid in children ages 6 to 17. CNN. Retrieved 22 March 2022, from https://www.cnn.com/2022/03/09/health/pfizer-paxlovid-pediatric-trial/index.html

Yang, M. (2022, February 28). Pfizer vaccine significantly less effective in children ages five to 11, study shows. The Guardian. https://www.theguardian.com/society/2022/feb/28/pfizer-vaccine-less-effective-children-ages-five-to-11-data

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Mancini, D. P., & Smyth, J. (2022, February 16). Merck struggles to win European approval for Covid-19 antiviral pill. Financial Times. https://www.ft.com/content/2cf0b6cc-b07b-4ff9-a833-42eb1798a576

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Mahase, E. (2022). Covid-19: What do we know about omicron sublineages? BMJ, 376, o358. https://doi.org/10.1136/bmj.o358

American Medical Association (AMA). (2021, December 6). Peter Hotez, MD, PhD, on the omicron variant and Delta winter surge | COVID-19 Update for Dec. 6, 20. https://www.youtube.com/watch?v=WnfpC1_N2Mg

Iketani, S., Liu, L., Guo, Y., Liu, L., Huang, Y., Wang, M., Luo, Y., Yu, J., Yin, M. T., Sobieszczyk, M. E., Huang, Y., Wang, H. H., Sheng, Z., & Ho, D. D. (2022). Antibody Evasion Properties of SARS-CoV-2 Omicron Sublineages (p. 2022.02.07.479306). bioRxiv. https://doi.org/10.1101/2022.02.07.479306

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PaedsHaemDoc. (2022, January 9). Had the misfortune (via @fatemperor) to come across Dr Paul Alexander -apparently credentialed yet in single blog post demonstrates perfectly either a disconnect from rational thought or deliberate misinformation spreading of the #masspsychosis of the anti-Vax crew let’s examine https://t.co/Ctd49cb1qK [Tweet]. @dr_barrett. https://twitter.com/dr_barrett/status/1479986071832248322

Meng, B., Abdullahi, A., Ferreira, I. A. T. M., Goonawardane, N., Saito, A., Kimura, I., Yamasoba, D., Gerber, P. P., Fatihi, S., Rathore, S., Zepeda, S. K., Papa, G., Kemp, S. A., Ikeda, T., Toyoda, M., Tan, T. S., Kuramochi, J., Mitsunaga, S., Ueno, T., … Gupta, R. K. (2022). Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity. Nature, 1–1. https://doi.org/10.1038/s41586-022-04474-x

Mahase, E. (2022). Omicron sub-lineage BA.2 may have “substantial growth advantage,” UKHSA reports. BMJ, 376, o263. https://doi.org/10.1136/bmj.o263

Devlin, H., & correspondent, H. D. S. (2022, February 3). Novavax Covid vaccine approved for use in over-18s in UK. The Guardian. https://www.theguardian.com/society/2022/feb/03/novavax-covid-vaccine-approved-for-use-in-over-18s-in-uk

ReconfigBehSci on Twitter: “RT @AliHMokdad: Vaccine effectiveness against BA.1 and BA.2. After 2 doses it was 9% (7-10%) and 13% (-26-40%) respectively for BA.1 and BA…” / Twitter. (n.d.). Retrieved January 30, 2022, from https://twitter.com/SciBeh/status/1487123660771106821

Which can lead to an assessment of pedagogical efficacy. It's funny, to me, that those who complain about "grade inflation" (typically admins) rarely entertain the notion that grades could be higher than usual if the course went well. The situation is quite different in "L&D" (Learning and Development, typically for training and professional development in an organizational context). "Oh, great! We were able to get everyone to reach the standard for this competency! Must mean that we've done something right in our Instructional Design!"

Yang, M. (2022, January 14). ‘Menace to public health’: 270 doctors criticize Spotify over Joe Rogan’s podcast. The Guardian. https://www.theguardian.com/technology/2022/jan/14/spotify-joe-rogan-podcast-open-letter

Augustin, E. (2022, January 5). Cuba’s vaccine success story sails past mark set by rich world’s Covid efforts. The Guardian. https://www.theguardian.com/world/2022/jan/05/cuba-coronavirus-covid-vaccines-success-story

Allyson Pollock. (2022, January 2). I am told that masks obey the law of physics! How does theory translate into practice? How often do you touch mask, wash it, shove it in your pocket? If you sneeze/cough do you a) take mask off, use a handkerchief, wash hands b) keep mask on -if so where does the snot go? [Tweet]. @AllysonPollock. https://twitter.com/AllysonPollock/status/1477737957054365696

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Vaccination among the pregnant lagging despite growing evidence of safety and efficacy. (2021, December 10). Healthy Debate. https://healthydebate.ca/2021/12/topic/vaccination-pregnant-safe-efficacy/

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Cause for optimism on Omicron: Our immune systems aren’t blank slates. (2021, December 1). STAT. https://www.statnews.com/2021/12/01/a-reason-for-optimism-on-omicron-our-immune-systems-are-not-blank-slates/

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FDA authorizes Pfizer-BioNTech, Moderna boosters for all adults. (2021). Washington Post. Retrieved November 22, 2021, from https://www.washingtonpost.com/health/2021/11/19/fda-clears-pfizer-biontech-moderna-booster-shots-all-adults/

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Prof Peter Hotez MD PhD. (2021, October 30). Many thanks @FWhitfield for hosting me this Saturday AM @CNN In case it’s helpful, I’ve prepared an informal ‘fact sheet’ on COVID in children and COVID vaccines in 5-11 age group. Highlights attached...feel free to RT or repurpose the information [Tweet]. @PeterHotez. https://twitter.com/PeterHotez/status/1454489603013062656

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Dowdy, D. (2021, September 21). On the J&J booster news, keep in mind: 1. Median follow-up since 2nd dose was just 36 days, 2. Efficacy vs moderate COVID was 75% globally, and 3. Total number of cases in the US was 15. Please don’t take this to mean that a 2nd dose provides long-term increase in protection. Https://t.co/RnqDNBmwuD [Tweet]. @davidwdowdy. https://twitter.com/davidwdowdy/status/1440323242942554122

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https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00628-0/fulltext

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