- Oct 2021
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blog.gdeltproject.org blog.gdeltproject.org
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Using The Global Relationship Graph To Examine Claims About Covid-19 Vaccination And Infertility Or Bell’s Palsy – The GDELT Project. (n.d.). Retrieved May 14, 2021, from https://blog.gdeltproject.org/using-the-global-relationship-graph-to-examine-claims-about-covid-19-vaccination-and-infertility-or-bells-palsy/
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Using The Global Relationship Graph To Examine Claims About Covid-19 Vaccination And Infertility Or Bell's Palsy
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Using the Global Relationship Graph's (GRG) Realtime Verb-Centered NGram Pilot, what can we learn about claims in English language media coverage about links between Covid-19 vaccinations and infertility or Bell's Palsy? The query below searches across the GRG, which today totals more than 850M relationships across English language news coverage dating back to October 27, 2020:
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Kington, R. S., Arnesen, S., Chou, W.-Y. S., Curry, S. J., Lazer, D., & Villarruel, and A. M. (2021). Identifying Credible Sources of Health Information in Social Media: Principles and Attributes. NAM Perspectives. https://doi.org/10.31478/202107a
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Identifying Credible Sources of Health Information in Social Media: Principles and Attributes
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Neville, S., Burn-Murdoch, J., & Bounds, A. (2021, May 27). UK virus cases hit 6-week high but vaccines diminish threat. Financial Times. https://www.ft.com/content/a5dc95ca-5869-46e1-b368-d6856adf414a
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UK virus cases hit 6-week high but vaccines diminish threat
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Rise in infections remains concentrated among younger, less vulnerable people
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Inasaridze, K. (2021). Therapy of depression by the method of behavioral activation. PsyArXiv. https://doi.org/10.31234/osf.io/rfq79
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www.theguardian.com www.theguardian.com
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Covid cases in England are 26 times higher than a year ago. (2021, August 28). The Guardian. http://www.theguardian.com/world/2021/aug/28/covid-cases-in-england-are-26-times-higher-than-a-year-ago
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orb-international.com orb-international.com
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orb-developer. (2021, June 4). Vaccine Confidence Tracker: UK. ORB International. https://orb-international.com/2021/06/04/vaccine-confidence-tracker-uk/
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Vaccine Confidence Tracker: UK
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Founded in 2010 The Vaccine Confidence Project (VCP) at the London School of Hygiene and Tropical Medicine (LSHTM) was developed to understand responses to hesitancy and misinformation on vaccination programmes. Today, the purpose of the project is to monitor public confidence in immunisation programmes through research and analysis.
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www.bloomberg.com www.bloomberg.com
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Delta Hospitalizes More U.S. Kids, Cuts Job Growth: Virus Update. (2021, September 2). Bloomberg.Com. https://www.bloomberg.com/news/articles/2021-09-02/fauci-floats-three-doses-u-s-hospitals-strained-virus-update
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www.sciencemag.org www.sciencemag.org
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Kupferschmidt, K., VogelMar. 27, G., 2021, & Am, 10:20. (2021, March 27). A rare clotting disorder may cloud the world’s hopes for AstraZeneca’s COVID-19 vaccine. Science | AAAS. https://www.sciencemag.org/news/2021/03/rare-clotting-disorder-may-cloud-worlds-hopes-astrazenecas-covid-19-vaccine
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A rare clotting disorder may cloud the world’s hopes for AstraZeneca’s COVID-19 vaccine
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Many European countries suspended use of AstraZeneca’s vaccine earlier this month following initial reports of the symptoms, which have led to at least 15 deaths. Most resumed vaccinations after the European Medicines Agency (EMA) recommended doing so on 18 March, saying the benefits of the vaccine outweigh any risks. EMA is continuing to investigate the matter and will convene a wide-ranging committee of experts on 29 March.
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www.theguardian.com www.theguardian.com
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Military doctors shore up exhausted health teams in US south amid Covid surge. (2021, September 7). The Guardian. https://www.theguardian.com/us-news/2021/sep/07/covid-us-south-military-doctors
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Covid: Royal Bolton Hospital taking “urgent action” over virus. (2021, May 25). BBC News. https://www.bbc.com/news/uk-england-manchester-57242368
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Covid: Royal Bolton Hospital taking 'urgent action' over virus
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assets.publishing.service.gov.uk assets.publishing.service.gov.uk
Tags
- influenza
- is:report
- Public Health England
- surveillance report
- UK
- monitoring
- COVID-19
- surveillance system
- summary
- lang:en
Annotators
URL
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www.theguardian.com www.theguardian.com
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Nicholas, J., & Evershed, N. (n.d.). Covid-19 vaccine Australia rollout tracker by state: total number of people and per cent vaccinated, daily vaccine doses and rate of progress. The Guardian. Retrieved September 20, 2021, from https://www.theguardian.com/australia-news/datablog/ng-interactive/2021/sep/20/covid-19-vaccine-rollout-australia-vaccination-rate-progress-how-many-people-vaccinated-percent-tracker-australian-states-number-total-daily-live-data-stats-updates-news-schedule-tracking-chart-percentage-new-cases-today
Tags
Annotators
URL
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www.climatechangecommunication.org www.climatechangecommunication.org
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The Conspiracy Theory Handbook | Center For Climate Change Communication. (n.d.). Retrieved March 3, 2021, from https://www.climatechangecommunication.org/conspiracy-theory-handbook/
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The Conspiracy Theory Handbook
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Conspiracy theories attempt to explain events as the secretive plots of powerful people. While conspiracy theories are not typically supported by evidence, this doesn’t stop them from blossoming. Conspiracy theories damage society in a number of ways. To help minimise these harmful effects, The Conspiracy Theory Handbook, by Stephan Lewandowsky and John Cook, explains why conspiracy theories are so popular, how to identify the traits of conspiratorial thinking, and what are effective response strategies.
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www.kingcounty.gov www.kingcounty.gov
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COVID-19 vaccine - King County. (n.d.). Retrieved March 2, 2021, from https://www.kingcounty.gov/depts/health/covid-19/vaccine.aspx
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COVID-19 vaccine
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Serra-Garcia, M., & Gneezy, U. (2021). Nonreplicable publications are cited more than replicable ones. Science Advances, 7(21), eabd1705. https://doi.org/10.1126/sciadv.abd1705
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Nonreplicable publications are cited more than replicable ones
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We use publicly available data to show that published papers in top psychology, economics, and general interest journals that fail to replicate are cited more than those that replicate. This difference in citation does not change after the publication of the failure to replicate. Only 12% of postreplication citations of nonreplicable findings acknowledge the replication failure. Existing evidence also shows that experts predict well which papers will be replicated. Given this prediction, why are nonreplicable papers accepted for publication in the first place? A possible answer is that the review team faces a trade-off. When the results are more “interesting,” they apply lower standards regarding their reproducibility.
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www.longcovid.org www.longcovid.org
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User, S. (n.d.). Long Covid Support. Long Covid. Retrieved August 19, 2021, from https://www.longcovid.org/
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www.youtube.com www.youtube.com
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Stephen Senn. (n.d.). Being wrong about randomisation v2. Retrieved July 5, 2021, from https://www.youtube.com/watch?v=nwVZMwb-wjc
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Being wrong about randomisation v2
Tags
Annotators
URL
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www.psychologicalscience.org www.psychologicalscience.org
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IJzerman, H., Dutra, N., Silan, M., Adetula, A., Brown, D. M. B., & Forscher, and P. (2021). Psychological Science Needs the Entire Globe. APS Observer, 34(5). https://www.psychologicalscience.org/observer/global-psych-science
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bmjopen.bmj.com bmjopen.bmj.com
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Kerr, J. R., Schneider, C. R., Recchia, G., Dryhurst, S., Sahlin, U., Dufouil, C., Arwidson, P., Freeman, A. L., & Linden, S. van der. (2021). Correlates of intended COVID-19 vaccine acceptance across time and countries: results from a series of cross-sectional surveys. BMJ Open, 11(8), e048025. https://doi.org/10.1136/bmjopen-2020-048025
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onlinelibrary.wiley.com onlinelibrary.wiley.com
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Juanchich, M., Sirota, M., Jolles, D., & Whiley, L. A. (n.d.). Are COVID-19 conspiracies a threat to public health? Psychological characteristics and health protective behaviours of believers. European Journal of Social Psychology, n/a(n/a). https://doi.org/10.1002/ejsp.2796
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Are COVID-19 conspiracies a threat to public health? Psychological characteristics and health protective behaviours of believers
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www.washingtonpost.com www.washingtonpost.com
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Keating, D., Johnson, A., & Ulmanu, M. (n.d.). The pandemic marks another grim milestone: 1 in 500 Americans have died of covid-19. Washington Post. Retrieved September 20, 2021, from https://www.washingtonpost.com/health/interactive/2021/1-in-500-covid-deaths/
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graphics.reuters.com graphics.reuters.com
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Sharma, M., Scarr, S., & Kell, K. (n.d.). Speed Science. Reuters. Retrieved August 19, 2021, from https://graphics.reuters.com/CHINA-HEALTH-RESEARCH/0100B5ES3MG/index.html
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psyarxiv.com psyarxiv.com
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Winter, T., Jose, P., Riordan, B., Bizumic, B., Ruffman, T., Hunter, J., Hartman, T. K., & Scarf, D. (2021). Left-wing support of authoritarian submission to protect against societal threat. PsyArXiv. https://doi.org/10.31234/osf.io/hu9ef
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Left-wing support of authoritarian submission to protect against societal threat
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psyarxiv.com psyarxiv.com
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Pennycook, G., & Rand, D. (2021). Nudging social media sharing towards accuracy. PsyArXiv. https://doi.org/10.31234/osf.io/tp6vy
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www.thelancet.com www.thelancet.com
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Emary, K. R. W., Golubchik, T., Aley, P. K., Ariani, C. V., Angus, B., Bibi, S., Blane, B., Bonsall, D., Cicconi, P., Charlton, S., Clutterbuck, E. A., Collins, A. M., Cox, T., Darton, T. C., Dold, C., Douglas, A. D., Duncan, C. J. A., Ewer, K. J., Flaxman, A. L., … Pollard, A. J. (2021). Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial. The Lancet, 0(0). https://doi.org/10.1016/S0140-6736(21)00628-0
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00628-0/fulltext
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Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial
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SummaryBackgroundA new variant of SARS-CoV-2, B.1.1.7, emerged as the dominant cause of COVID-19 disease in the UK from November, 2020. We report a post-hoc analysis of the efficacy of the adenoviral vector vaccine, ChAdOx1 nCoV-19 (AZD1222), against this variant.MethodsVolunteers (aged ≥18 years) who were enrolled in phase 2/3 vaccine efficacy studies in the UK, and who were randomly assigned (1:1) to receive ChAdOx1 nCoV-19 or a meningococcal conjugate control (MenACWY) vaccine, provided upper airway swabs on a weekly basis and also if they developed symptoms of COVID-19 disease (a cough, a fever of 37·8°C or higher, shortness of breath, anosmia, or ageusia). Swabs were tested by nucleic acid amplification test (NAAT) for SARS-CoV-2 and positive samples were sequenced through the COVID-19 Genomics UK consortium. Neutralising antibody responses were measured using a live-virus microneutralisation assay against the B.1.1.7 lineage and a canonical non-B.1.1.7 lineage (Victoria). The efficacy analysis included symptomatic COVID-19 in seronegative participants with a NAAT positive swab more than 14 days after a second dose of vaccine. Participants were analysed according to vaccine received. Vaccine efficacy was calculated as 1 − relative risk (ChAdOx1 nCoV-19 vs MenACWY groups) derived from a robust Poisson regression model. This study is continuing and is registered with ClinicalTrials.gov, NCT04400838, and ISRCTN, 15281137.FindingsParticipants in efficacy cohorts were recruited between May 31 and Nov 13, 2020, and received booster doses between Aug 3 and Dec 30, 2020. Of 8534 participants in the primary efficacy cohort, 6636 (78%) were aged 18–55 years and 5065 (59%) were female. Between Oct 1, 2020, and Jan 14, 2021, 520 participants developed SARS-CoV-2 infection. 1466 NAAT positive nose and throat swabs were collected from these participants during the trial. Of these, 401 swabs from 311 participants were successfully sequenced. Laboratory virus neutralisation activity by vaccine-induced antibodies was lower against the B.1.1.7 variant than against the Victoria lineage (geometric mean ratio 8·9, 95% CI 7·2–11·0). Clinical vaccine efficacy against symptomatic NAAT positive infection was 70·4% (95% CI 43·6–84·5) for B.1.1.7 and 81·5% (67·9–89·4) for non-B.1.1.7 lineages.InterpretationChAdOx1 nCoV-19 showed reduced neutralisation activity against the B.1.1.7 variant compared with a non-B.1.1.7 variant in vitro, but the vaccine showed efficacy against the B.1.1.7 variant of SARS-CoV-2.
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covid19scenariomodelinghub.org covid19scenariomodelinghub.org
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Home - COVID 19 scenario model hub. (n.d.). Retrieved July 5, 2021, from https://covid19scenariomodelinghub.org/
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Scenario Modeling Hub
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Even the best models of emerging infections struggle to give accurate forecasts at time scales greater than 3-4 weeks due to unpredictable drivers such as a changing policy environment, behavior change, the development of new control measures, and stochastic events. However, policy decisions around the course of emerging infections often require projections in the time frame of months. The goal of long-term projections is to compare outbreak trajectories under different scenarios, as opposed to offering a specific, unconditional estimate of what “will” happen.
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www.pnas.org www.pnas.org
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Sah, P., Fitzpatrick, M. C., Zimmer, C. F., Abdollahi, E., Juden-Kelly, L., Moghadas, S. M., Singer, B. H., & Galvani, A. P. (2021). Asymptomatic SARS-CoV-2 infection: A systematic review and meta-analysis. Proceedings of the National Academy of Sciences, 118(34). https://doi.org/10.1073/pnas.2109229118
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replicationnetwork.com replicationnetwork.com
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replicationnetwork. (2021, May 18). DUAN & REED: How Are Meta-Analyses Different Across Disciplines? The Replication Network. https://replicationnetwork.com/2021/05/18/duan-reed-how-are-meta-analyses-different-across-disciplines/
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How Are Meta-Analyses Different Across Disciplines?
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Recently, one of us gave a workshop on how to conduct meta-analyses. The workshop was attended by participants from a number of different disciplines, including economics, finance, psychology, management, and health sciences. During the course of the workshop, it became apparent that different disciplines conduct meta-analyses differently. While there is a vague awareness that this is the case, we are unaware of any attempts to quantify those differences. That is the motivation for this blog.
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www.theatlantic.com www.theatlantic.com
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Yong, E. (2021, September 1). Long-Haulers Are Fighting for Their Future. The Atlantic. https://www.theatlantic.com/science/archive/2021/09/covid-19-long-haulers-pandemic-future/619941/
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link.springer.com link.springer.com
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Shahsavari, S., Holur, P., Wang, T., Tangherlini, T. R., & Roychowdhury, V. (2020). Conspiracy in the time of corona: automatic detection of emerging COVID-19 conspiracy theories in social media and the news. Journal of Computational Social Science, 3(2), 279–317. https://doi.org/10.1007/s42001-020-00086-5
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Conspiracy in the time of corona: automatic detection of emerging COVID-19 conspiracy theories in social media and the news
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Rumors and conspiracy theories thrive in environments of low confidence and low trust. Consequently, it is not surprising that ones related to the COVID-19 pandemic are proliferating given the lack of scientific consensus on the virus’s spread and containment, or on the long-term social and economic ramifications of the pandemic. Among the stories currently circulating in US-focused social media forums are ones suggesting that the 5G telecommunication network activates the virus, that the pandemic is a hoax perpetrated by a global cabal, that the virus is a bio-weapon released deliberately by the Chinese, or that Bill Gates is using it as cover to launch a broad vaccination program to facilitate a global surveillance regime. While some may be quick to dismiss these stories as having little impact on real-world behavior, recent events including the destruction of cell phone towers, racially fueled attacks against Asian Americans, demonstrations espousing resistance to public health orders, and wide-scale defiance of scientifically sound public mandates such as those to wear masks and practice social distancing, countermand such conclusions. Inspired by narrative theory, we crawl social media sites and news reports and, through the application of automated machine-learning methods, discover the underlying narrative frameworks supporting the generation of rumors and conspiracy theories. We show how the various narrative frameworks fueling these stories rely on the alignment of otherwise disparate domains of knowledge, and consider how they attach to the broader reporting on the pandemic. These alignments and attachments, which can be monitored in near real time, may be useful for identifying areas in the news that are particularly vulnerable to reinterpretation by conspiracy theorists. Understanding the dynamics of storytelling on social media and the narrative frameworks that provide the generative basis for these stories may also be helpful for devising methods to disrupt their spread.
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www.nature.com www.nature.com
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Telenti, A., Arvin, A., Corey, L., Corti, D., Diamond, M. S., García-Sastre, A., Garry, R. F., Holmes, E. C., Pang, P., & Virgin, H. W. (2021). After the pandemic: perspectives on the future trajectory of COVID-19. Nature, 1–14. https://doi.org/10.1038/s41586-021-03792-w
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After the pandemic: perspectives on the future trajectory of COVID-19
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www.sciencemag.org www.sciencemag.org
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CohenMay. 6, J., 2021, & Pm, 2:45. (2021, May 6). Further evidence supports controversial claim that SARS-CoV-2 genes can integrate with human DNA. Science | AAAS. https://www.sciencemag.org/news/2021/05/further-evidence-offered-claim-genes-pandemic-coronavirus-can-integrate-human-dna
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Further evidence supports controversial claim that SARS-CoV-2 genes can integrate with human DNA
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A team of prominent scientists has doubled down on its controversial hypothesis that genetic bits of the pandemic coronavirus can integrate into our chromosomes and stick around long after the infection is over. If they are right—skeptics have argued that their results are likely lab artifacts—the insertions could explain the rare finding that people can recover from COVID-19 but then test positive for SARS-CoV-2 again months later.
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Blomberg, B., Mohn, K. G.-I., Brokstad, K. A., Zhou, F., Linchausen, D. W., Hansen, B.-A., Lartey, S., Onyango, T. B., Kuwelker, K., Sævik, M., Bartsch, H., Tøndel, C., Kittang, B. R., Cox, R. J., & Langeland, N. (2021). Long COVID in a prospective cohort of home-isolated patients. Nature Medicine, 1–7. https://doi.org/10.1038/s41591-021-01433-3
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Long COVID in a prospective cohort of home-isolated patients
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Long COVID in a prospective cohort of home-isolated patients
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Long-term complications after coronavirus disease 2019 (COVID-19) are common in hospitalized patients, but the spectrum of symptoms in milder cases needs further investigation. We conducted a long-term follow-up in a prospective cohort study of 312 patients—247 home-isolated and 65 hospitalized—comprising 82% of total cases in Bergen during the first pandemic wave in Norway. At 6 months, 61% (189/312) of all patients had persistent symptoms, which were independently associated with severity of initial illness, increased convalescent antibody titers and pre-existing chronic lung disease. We found that 52% (32/61) of home-isolated young adults, aged 16–30 years, had symptoms at 6 months, including loss of taste and/or smell (28%, 17/61), fatigue (21%, 13/61), dyspnea (13%, 8/61), impaired concentration (13%, 8/61) and memory problems (11%, 7/61). Our findings that young, home-isolated adults with mild COVID-19 are at risk of long-lasting dyspnea and cognitive symptoms highlight the importance of infection control measures, such as vaccination.
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Miller, A. (2021, August 27). States Pull Back on Covid Data Even Amid Delta Surge. Kaiser Health News. https://khn.org/news/article/states-pull-back-on-covid-data-even-amid-delta-surge/
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Miller, A. (2021, August 27). States Pull Back on Covid Data Even Amid Delta Surge. Kaiser Health News. https://khn.org/news/article/states-pull-back-on-covid-data-even-amid-delta-surge/
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www.bmj.com www.bmj.com
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Wise, J. (2021). Long covid: One in seven children may still have symptoms 15 weeks after infection, data show. BMJ, 374, n2157. https://doi.org/10.1136/bmj.n2157
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uclpartners.com uclpartners.com
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Involving patients from the very beginning for COVID rehabilitation. (n.d.). UCLPartners. Retrieved September 2, 2021, from https://uclpartners.com/blog-post/involving-patients-from-the-very-beginning-for-covid-rehabilitation/
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www.tandfonline.com www.tandfonline.com
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Davies, A., Seaton, A., Tonooka, C., & White, J. (2021). Covid-19, online workshops, and the future of intellectual exchange. Rethinking History, 25(2), 224–241. https://doi.org/10.1080/13642529.2021.1934290
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Covid-19, online workshops, and the future of intellectual exchange
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blog.gdeltproject.org blog.gdeltproject.org
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BigQuery + UDF = Identifying The Earliest Glimmers Of Covid-19 – The GDELT Project. (n.d.). Retrieved May 14, 2021, from https://blog.gdeltproject.org/bigquery-udf-identifying-the-earliest-glimmers-of-covid-19/
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BigQuery + UDF = Identifying The Earliest Glimmers Of Covid-19
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The GKG 2.0 is essentially a realtime metadata index over the world's news in 65 languages dating back to 2015. A typical use case is to filter it to identify coverage mentioning a specific topic or location or combination of both. However, a simple filter that just looks for articles containing a given topic in the V2Themes field and a given location in the V2Locations field will yield a lot of irrelevant matches, since the topic of interest might be mentioned at the start of the article and the location of interest mentioned in an unrelated context at the bottom. Thus, when BigQuery first debuted the ability to use custom JavaScript User Defined Functions (UDF's), we showcased how a simple UDF could be used to parse through the V2Locations field to identify each distinct location mention in the article, then parse the V2Themes field and assign each theme mention to the nearest location mention in the text within a given window. In other words, it takes each location mention in an article and compiles a list of the themes mentioned within a given number of characters of that location in the text under the assumption that if "quarantine" is mentioned within a few words of "California" they are potentially related.
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www.timesofisrael.com www.timesofisrael.com
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AFP. (n.d.). Early Israeli data signals Delta strain may bypass vaccine, cause mild illness. Retrieved September 9, 2021, from https://www.timesofisrael.com/early-israeli-data-signals-delta-strain-may-bypass-vaccine-cause-mild-illness/
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ourworldindata.org ourworldindata.org
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Coronavirus Pandemic Data Explorer. (n.d.). Our World in Data. Retrieved March 3, 2021, from https://ourworldindata.org/coronavirus-data-explorer
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Coronavirus PandemicData Explorer
Tags
- Poland
- Guernsey
- Ethiopia
- Norway
- Barbados
- Bhutan
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- test
- Vietnam
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- Oceania
- Saint Helena
- Seychelles
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- ann:title
Annotators
URL
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www.timesofisrael.com www.timesofisrael.com
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Staff, T. (n.d.). 23 people caught trying to fly from Israel to New York with forged COVID tests. Retrieved August 13, 2021, from https://www.timesofisrael.com/23-people-caught-trying-to-fly-from-israel-to-new-york-with-forged-covid-tests/
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scopeblog.stanford.edu scopeblog.stanford.edu
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Duff-Brown, A. B. (2021, July 1). Racial, ethnic disparities in COVID-19 vaccination coverage. Scope. https://scopeblog.stanford.edu/2021/07/01/racial-ethnic-disparities-in-covid-19-vaccination-coverage/
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Racial, ethnic disparities in COVID-19 vaccination coverage
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qap.ecdc.europa.eu qap.ecdc.europa.eu
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COVID-19 | European Centre for Disease Prevention and Control. (n.d.). Retrieved March 1, 2021, from https://qap.ecdc.europa.eu/public/extensions/COVID-19/COVID-19.html#global-overview-tab
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COVID-19 Situation Dashboard
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www.cnn.com www.cnn.com
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CNN, R. J. (n.d.). “Tell all your TikTok buddies to get vaccinated”: Fauci finds a new way to fight Covid-19. CNN. Retrieved August 19, 2021, from https://www.cnn.com/2021/07/03/politics/fauci-tiktok-youth-vaccinations/index.html
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www.theatlantic.com www.theatlantic.com
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Yong, E. (2021, August 12). How the Pandemic Now Ends. The Atlantic. https://www.theatlantic.com/health/archive/2021/08/delta-has-changed-pandemic-endgame/619726/
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www.scientificamerican.com www.scientificamerican.com
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Yee, A. (n.d.). COVID’s Outsize Impact on Asian Americans Is Being Ignored. Scientific American. Retrieved May 14, 2021, from https://www.scientificamerican.com/article/covids-outsize-impact-on-asian-americans-is-being-ignored/
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COVID’s Outsize Impact on Asian Americans Is Being Ignored
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Along with Pacific Islanders, they suffer from disproportionately high death rates and hospitalizations and low testing—but their suffering remains invisible
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scibeh.org scibeh.org
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Viewer. (n.d.). SciBeh. Retrieved February 26, 2021, from https://scibeh.org/viewer/
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www.propublica.org www.propublica.org
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Marco, M. A., Meg. (n.d.). How Your Brain Tricks You Into Taking Risks During the Pandemic. ProPublica. Retrieved September 2, 2021, from https://www.propublica.org/article/how-your-brain-tricks-you-into-taking-risks-during-the-pandemic?token=l24Nh-wDyBgy53bhcy5jGvQh1IDRcxzE
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uk.sagepub.com uk.sagepub.com
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Collective Intelligence. (2020, July 18). SAGE Publications Ltd. https://uk.sagepub.com/en-gb/eur/collective-intelligence/journal203713
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Collective Intelligence
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Collective Intelligence, co-published by SAGE and the Association for Computing Machinery (ACM), with the collaboration of Nesta, is a global, peer-reviewed, open-access journal that publishes trans-disciplinary work bearing on collective intelligence across the disciplines. The journal embraces a policy of creative rigor in the study of collective intelligence to facilitate the discovery of principles that apply across scales and new ways of harnessing the collective to improve social, ecological, and economic outcomes. In that spirit, the journal encourages a broad-minded approach to collective performance. We welcome perspectives that emphasize traditional views of intelligence as well as optimality, satisficing, robustness, adaptability, and wisdom. In more technical terms, this includes issues related to collective output quality and assessment, aggregation of information and related topics (e.g., network structure and dynamics, higher-order vs. pairwise interactions, spatial and temporal synchronization, diversity, etc.), accumulation of information by individuals/components, environmental complexity, evolutionary considerations, and design of systems and platforms fostering collective intelligence.
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www.vaccinestoday.eu www.vaccinestoday.eu
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Finnegan, G. (2021, September 8). How France overcame COVID-19 vaccine scepticism. VaccinesToday. https://www.vaccinestoday.eu/stories/how-france-overcame-covid-19-vaccine-scepticism/
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www.scientificamerican.com www.scientificamerican.com
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Currin, G. (n.d.). YouTube’s Plan to Showcase Credible Health Information Is Flawed, Experts Warn. Scientific American. Retrieved September 3, 2021, from https://www.scientificamerican.com/article/youtubes-plan-to-showcase-credible-health-information-is-flawed-experts-warn/
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www.eventbrite.com www.eventbrite.com
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Human Centered Design Workshop for PPE. (n.d.). Eventbrite. Retrieved March 3, 2021, from https://www.eventbrite.com/e/136323937567?aff=efbneb
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HMW improve mask comfort, sociability AND Safety?
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This workshop will provide design researchers with an introductory assessment of the landscape of current options in terms of the CARES experience methodology
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publicintegrity.org publicintegrity.org
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Spreading vaccine fears. And cashing in. (n.d.). Center for Public Integrity. Retrieved June 21, 2021, from https://publicintegrity.org/health/coronavirus-and-inequality/spreading-fears-cashing-in-anti-vaccine/
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Spreading vaccine fears. And cashing in.
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mriids.org mriids.orgMRIIDS1
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MRIIDS. (n.d.). Retrieved September 6, 2021, from https://mriids.org/about
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english.elpais.com english.elpais.com
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Salas, M. Z., Javier. (2020, October 28). A room, a bar and a classroom: how the coronavirus is spread through the air. EL PAÍS. https://english.elpais.com/society/2020-10-28/a-room-a-bar-and-a-class-how-the-coronavirus-is-spread-through-the-air.html
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A room, a bar and a classroom: how the coronavirus is spread through the air
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The risk of contagion is highest in indoor spaces but can be reduced by applying all available measures to combat infection via aerosols. Here is an overview of the likelihood of infection in three everyday scenarios, based on the safety measures used and the length of exposure
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www.euractiv.com www.euractiv.com
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Heller, F. (2021, January 13). Spain to launch Whatsapp channel to fight vaccine disinformation. Www.Euractiv.Com. https://www.euractiv.com/section/digital/news/spain-to-launch-whatsapp-channel-to-fight-vaccine-disinformation/
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Spain to launch Whatsapp channel to fight vaccine disinformation
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Spain’s health ministry will soon launch a WhatsApp interactive channel to fight against disinformation on COVID-19 vaccines, El País reported. This should help reduce the percentage of Spaniards who still refuse to get vaccinated. EURACTIV’s partner EuroEfe reports.
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www.wired.co.uk www.wired.co.uk
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They Claimed the Covid Vaccine Made Them Sick—and Went Viral. (n.d.). Wired. Retrieved March 1, 2021, from https://www.wired.co.uk/article/covid-vaccine-misinformation-facebook
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They Claimed the Covid Vaccine Made Them Sick—and Went Viral
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On Facebook, videos of people reporting disturbing side effects from the shots have been viewed by millions. Fact-checking efforts can't keep up.
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blog.gdeltproject.org blog.gdeltproject.org
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Announcing The Global Numeric Graph – The GDELT Project. (n.d.). Retrieved May 14, 2021, from https://blog.gdeltproject.org/announcing-the-global-numeric-graph/
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Announcing The Global Numeric Graph
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We are tremendously excited to announce today the debut of the GDELT Global Numeric Graph (GNG), which compiles appearances of numeric statements across worldwide online news coverage in 152 languages. Each article monitored by GDELT is scanned for all appearances of numbers, either in the numeric characters of the given language for all 152 languages or, for around 100 languages and growing, spelled numbers (ie "one million" or "fifty" in English). Each appearance is compiled along with a brief context of how the number was used and the articles that specific number-in-context was seen in. This inaugural release compiles nearly 3.8 billion numeric references across 152 languages dating back to January 1, 2020.
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blog.gdeltproject.org blog.gdeltproject.org
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Quantifying The COVID-19 Public Health Media Narrative Through TV & Radio News Analysis – The GDELT Project. (n.d.). Retrieved May 14, 2021, from https://blog.gdeltproject.org/quantifying-the-covid-19-public-health-media-narrative-through-tv-radio-news-analysis/
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Quantifying The COVID-19 Public Health Media Narrative Through TV & Radio News Analysis
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Quantifying The COVID-19 Public Health Media Narrative Through TV & Radio News Analysis
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How does the COVID-19 narrative differ across television, radio and online news and across outlets? Is COVID-19 being covered differently than past disease outbreaks like Ebola or Zika and what can we learn from those communication efforts that could help inform public health communication about the current pandemic? To help answer these critical questions, the M-DRC is working with GDELT to use Google’s Cloud Video and Cloud Speech To Text APIs to non-consumptively analyze selections of the Internet Archive’s Television News Archive and Radio News Archive in a secure research environment, analyzing in total more than 4.9 million minutes of television news across 1,113 days 2009-present and 2.5 million minutes of radio since the start of this year to create an open set of non-consumptive annotations to enable public health communication research on how the COVID-19 pandemic has been communicated to the public and how those communicative efforts compare with the pandemics of the past decade, including Cholera, Ebola, E. coli, Measles, MERS, Salmonella and Zika and a portion of the opioid epidemic.
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blog.gdeltproject.org blog.gdeltproject.org
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A Timeline Of Infection, Death And Vaccination Count Mentions In The News During Covid-19 Using The Global Numeric Graph – The GDELT Project. (n.d.). Retrieved May 14, 2021, from https://blog.gdeltproject.org/a-timeline-of-infection-death-and-vaccination-count-mentions-in-the-news-during-covid-19-using-the-global-numeric-graph/
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A Timeline Of Infection, Death And Vaccination Count Mentions In The News During Covid-19 Using The Global Numeric Graph
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Using the new Global Numeric Graph announced yesterday, which tracks global mentions of precise numeric counts in worldwide news coverage in 152 languages in realtime back to January 1, 2020, what does the Covid-19 pandemic look like in terms of how often disease-related numbers have appeared in the news? Using the simple queries below, we searched all appearances of numeric counts across English language news coverage monitored by GDELT from January 1, 2020 through May 9, 2021 and counted the total number of numeric statements per day that mentioned either "deaths/dead/died/dying" in context with the number, "infect*" or "vaccin*" to count how many numbers across the monitored English coverage each day were associated with these three topics. Note that this counts how many times per day a number was expressed in text alongside one of these three sets of keywords, not the actual death/infection/vaccination count itself. In other words, if an article states "more than 3,000 have died in the last 24 hours", we would record that the topic of death appeared alongside a number once in the article, not that 3,000 people died. In other words, we are looking at how prevalent death, infections and vaccinations were in global English language news coverage day by day over the course of the pandemic.
Tags
- disease
- global
- relation
- global numeric graph
- ann:summary
- is:webpage
- ann:title
- vaccine
- infection
- graph
- COVID-19
- death
- mention
- lang:en
- news
Annotators
URL
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www.uclhospitals.brc.nihr.ac.uk www.uclhospitals.brc.nihr.ac.uk
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Pavord, S., Scully, M., Hunt, B. J., Lester, W., Bagot, C., Craven, B., Rampotas, A., Ambler, G., & Makris, M. (2021). Clinical Features of Vaccine-Induced Immune Thrombocytopenia and Thrombosis. New England Journal of Medicine, NEJMoa2109908. https://doi.org/10.1056/NEJMoa2109908
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blog.gdeltproject.org blog.gdeltproject.org
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A Daily Timeline Of Key Vaccine Topics In 2021 Through A TF-IDF BigQuery Analysis Of The Global Relationship Graph – The GDELT Project. (n.d.). Retrieved May 14, 2021, from https://blog.gdeltproject.org/a-daily-timeline-of-key-vaccine-topics-in-2021-through-a-tf-idf-bigquery-analysis-of-the-global-relationship-graph/
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A Daily Timeline Of Key Vaccine Topics In 2021 Through A TF-IDF BigQuery Analysis Of The Global Relationship Graph
Tags
- global
- association
- is:webpage
- global relationship graph
- vaccine
- graph
- phrase
- language
- ann:title
- lang:en
- word
Annotators
URL
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blog.gdeltproject.org blog.gdeltproject.org
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Using The Global Quotation Graph To Examine Statements About Covid-19 Vaccination And Infertility Or Bell’s Palsy – The GDELT Project. (n.d.). Retrieved May 14, 2021, from https://blog.gdeltproject.org/using-the-global-quotation-graph-to-examine-statements-about-covid-19-vaccination-and-infertility-or-bells-palsy/
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Using the Global Quotation Graph (GQG), what can we learn about public statements quoted in English language online media about links between Covid-19 vaccinations and infertility or Bell's Palsy? The query below searches across the quote itself and the text immediately before and after it, searching the English portion of the full GQG, which totals 164 million quoted statements across 152 languages spanning January 1, 2020 through present:
Tags
- global
- ann:summary
- infertility
- online media
- is:webpage
- vaccine
- public
- graph
- COVID-19
- Bell's Palsy
- lang:en
Annotators
URL
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tnicholsmd.medium.com tnicholsmd.medium.com
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Nichols, T. (2021, July 19). COVID Isn’t Over, And Why That Will Impact Everyone. Medium. https://tnicholsmd.medium.com/covid-isnt-over-and-why-that-will-impact-everyone-ce94766669df
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www.theatlantic.com www.theatlantic.com
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Bastian, H. (2021, June 24). The mRNA Vaccines Are Extraordinary, but Novavax Is Even Better. The Atlantic. https://www.theatlantic.com/health/archive/2021/06/novavax-now-best-covid-19-vaccine/619276/
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The mRNA Vaccines Are Extraordinary, but Novavax Is Even Better
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www.imperial.ac.uk www.imperial.ac.uk
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Real-time Assessment of Community Transmission findings. (n.d.). Imperial College London. Retrieved August 18, 2021, from http://www.imperial.ac.uk/medicine/research-and-impact/groups/react-study/real-time-assessment-of-community-transmission-findings/
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Bekkers, R. (2021). Course Manual: Replication and Preregistration in the Social Sciences. https://osf.io/bh3yp/
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www.newscientist.com www.newscientist.com
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Vaughan, A. (n.d.). Scientists call for urgent investigation into covid-19 animal origins. New Scientist. Retrieved September 2, 2021, from https://www.newscientist.com/article/2287934-scientists-call-for-urgent-investigation-into-covid-19-animal-origins/
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www.nejm.org www.nejm.org
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Covid-19 Vaccine Resource Center. (n.d.). Https://Www.Nejm.Org. Retrieved July 19, 2021, from https://www.nejm.org/covid-vaccine
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Covid-19 Vaccine Resource Center
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A magnet won’t stick to a glass vaccine vial. (2021, June 7). Full Fact. https://fullfact.org/online/covid-vaccine-vial-magnetic/
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A magnet won’t stick to a glass vaccine vial
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api.gdeltproject.org api.gdeltproject.org
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GDELT Summary: Television Explorer: hydroxychloroquine AND (Station:CNN OR Station:FOXNEWS OR Station:MSNBC) AND PublicationDate>=3/1/2020. (n.d.). Retrieved May 14, 2021, from https://api.gdeltproject.org/api/v2/summary/summary?d=iatv&t=summary&k=hydroxychloroquine+&ts=custom&sdt=20200301000000&fs=station%3ACNN&fs=station%3AFOXNEWS&fs=station%3AMSNBC&svt=zoom&swvt=zoom&ssc=yes&sshc=yes&swc=yes&stcl=yes&c=1
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Television Explorer
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Below is a visual dashboard summary of broadcast television news coverage of your search using data from the Internet Archive's Television News Archive. While the index is updated every 15 minutes, broadcasts take 24-48 hours to become available for search, so results for the past two days are incomplete. Refresh this page again in 15 minutes to see the most recent updates. Displays work best in Google Chrome.
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datastudio.google.com datastudio.google.com
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COVIDGlobal Misinformation Dashboard 2020-21. (n.d.). Google Data Studio. Retrieved August 19, 2021, from http://datastudio.google.com/reporting/87b00158-5589-4154-a81b-c17cdb0d0d19/page/Kn2IB?feature=opengraph
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www.healthaffairs.org www.healthaffairs.org
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Four Steps To Help Achieve COVID-19 Vaccine Adoption: How Health Professionals Can Embrace Their Role As Messengers | Health Affairs Blog. (n.d.). Retrieved May 28, 2021, from https://www.healthaffairs.org/do/10.1377/hblog20210121.500910/full/
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Four Steps To Help Achieve COVID-19 Vaccine Adoption: How Health Professionals Can Embrace Their Role As Messengers
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Four Steps To Help Achieve COVID-19 Vaccine Adoption: How Health Professionals Can Embrace Their Role As Messengers
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Recently, the Centers for Disease Control and Prevention (CDC) announced updates about reactions to COVID-19 vaccines. They reported that—as of December 18, 2020—3,150 of the 112,807 (2.8 percent) people receiving a first dose reported “health impact events” requiring missing work or seeing a doctor. These numbers may appear frightening, but data from clinical trials are reassuring that Pfizer and Moderna COVID-19 vaccine side effects are generally mild. The country needs to ensure Americans understand that rising absolute numbers of side effects need not imply a higher rate of reactions—nor that the risk-benefit profiles have changed.
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Recently, the Centers for Disease Control and Prevention (CDC) announced updates about reactions to COVID-19 vaccines. They reported that—as of December 18, 2020—3,150 of the 112,807 (2.8 percent) people receiving a first dose reported “health impact events” requiring missing work or seeing a doctor. These numbers may appear frightening, but data from clinical trials are reassuring that Pfizer and Moderna COVID-19 vaccine side effects are generally mild. The country needs to ensure Americans understand that rising absolute numbers of side effects need not imply a higher rate of reactions—nor that the risk-benefit profiles have changed.
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publichealthcollaborative.org publichealthcollaborative.org
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Misinformation Alerts - Public Health Communications Collaborative. (n.d.). Public Health Communication Collaborative. Retrieved September 24, 2021, from https://publichealthcollaborative.org/misinformation-alerts/
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docs.google.com docs.google.com
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Understanding COVID-19 Registration Form. (n.d.). Google Docs. Retrieved March 31, 2021, from https://docs.google.com/forms/d/e/1FAIpQLScrC4krKVHcSm_Wi2VcXcGHa4F8l3cilL2xhbB62etcK4sy4w/viewform?usp=embed_facebook
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Understanding COVID-19 Registration Form
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yougov.co.uk yougov.co.uk
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Europe is becoming more pro-vaccine | YouGov. (n.d.). Retrieved March 1, 2021, from https://yougov.co.uk/topics/international/articles-reports/2021/01/22/europe-becoming-more-pro-vaccine
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Europe is becoming more pro-vaccine
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People in nine key European nations are noticeably more willing to get vaccinated against coronavirus
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Frank Luntz. (n.d.). Frank Luntz shares why half of Americans are still unvaccinated. Retrieved August 13, 2021, from https://www.youtube.com/watch?v=LkzRtxtzGTs
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British Asian celebrities unite for video to dispel Covid vaccine myths
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Celebrities including comedians Romesh Ranganathan and Meera Syal and cricketer Moeen Ali have made a video urging people to get the Covid vaccine.
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www.irishtimes.com www.irishtimes.com
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Hungary buys Sputnik vaccines for 1m people, saying EU has been ‘too slow’
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Hungary has agreed to buy enough doses of Russia’s Sputnik V vaccine to inoculate 1 million people against coronavirus, becoming the first EU member to turn to Moscow after complaining about the pace of the bloc’s own vaccine procurement programme.
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www.youtube.com www.youtube.com
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SIOP/CARMA Open Science Virtual Summer Series, May&June 2021!
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www.tagesschau.de www.tagesschau.de
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Komplett verdrehte Aussage
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Ein Pharmakonzern soll die Impfstoffentwicklung gegen das Coronavirus eingestellt haben, weil es besser wäre, infiziert zu werden und sein Immunsystem arbeiten zu lassen. Aber diese Behauptung stimmt nicht.
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Addressing COVID-19 Misinformation on Social Media Preemptively and Responsively
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Efforts to address misinformation on social media have special urgency with the emergence of coronavirus disease (COVID-19). In one effort, the World Health Organization (WHO) designed and publicized shareable infographics to debunk coronavirus myths. We used an experiment to test the efficacy of these infographics, depending on placement and source. We found that exposure to a corrective graphic on social media reduced misperceptions about the science of 1 false COVID-19 prevention strategy but did not affect misperceptions about prevention of COVID-19. Lowered misperceptions about the science persisted >1 week later. These effects were consistent when the graphic was shared by the World Health Organization or by an anonymous Facebook user and when the graphics were shared preemptively or in response to misinformation. Health organizations can and should create and promote shareable graphics to improve public knowledge.
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www.cnn.com www.cnn.com
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Xi Jinping touts coronavirus cooperation as China persists with vaccine disinformation push
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China has been praised for its "vaccine diplomacy," promising shots to developing countries and investing in vaccine candidates that do not require expensive cold storage to be effective. But as questions have been raised over the effectiveness of one of those vaccines, the country's state media has reacted aggressively, targeting not just critics but also other vaccines, in an apparent effort to tear down their reputation in the name of defending the Chinese shots.
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www.youtube.com www.youtube.com
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#StratComTalks Vaccines and Disinformation
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This episode of #StratComTalks looks at how this disinformation spreads vis-à-vis vaccination and how governments can prepare for this communications challenge.
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www.frontiersin.org www.frontiersin.org
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Inoculating Against Fake News About COVID-19
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The outbreak of the SARS-CoV-2 novel coronavirus (COVID-19) has been accompanied by a large amount of misleading and false information about the virus, especially on social media. In this article, we explore the coronavirus “infodemic” and how behavioral scientists may seek to address this problem. We detail the scope of the problem and discuss the negative influence that COVID-19 misinformation can have on the widespread adoption of health protective behaviors in the population. In response, we explore how insights from the behavioral sciences can be leveraged to manage an effective societal response to curb the spread of misinformation about the virus. In particular, we discuss the theory of psychological inoculation (or prebunking) as an efficient vehicle for conferring large-scale psychological resistance against fake news.
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Covid-19: Millions could be offered booster vaccinations from September
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Covid-19 booster vaccinations should be offered in England from September 2021, the Joint Committee on Vaccination and Immunisation has advised. But some experts have questioned the necessity and the practicalities of the plan.
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What scientists know about new, fast-spreading coronavirus variants
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Key questions remain about how quickly B.1.617 variants can spread, their potential to evade immunity and how they might affect the course of the pandemic.
Tags
Annotators
URL
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www.youtube.com www.youtube.com
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COVID Course 3 17 21
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This short video seeks to inform high school students about an opportunity to attend a 2 day virtual course April 20 and 21 entitled "COVID-19: Evolution of a Pandemic". In this course students will learn where the virus came from, how it causes disease, why viruses are existential threats to humanity, how treatments are discovered and how vaccines are made. In addition, we will discuss how policy and advocacy influence the course of pandemics, when life will get back to normal, and how worried we should be about future pandemics and what we can do now to prevent future pandemics.
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www.theguardian.com www.theguardian.com
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MPs’ report scathing on UK’s handling and sharing of Covid data
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Committee says government’s lack of sufficient explanation has placed needless strain on public confidence
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www.youtube.com www.youtube.com
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#COVID19 LIVE Q&A virus variants with Dr M. Ryan and Dr M. Van Kerkhove - #AskWHO of 27 January 2021
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#AskWHO series: This was the live discussion of 27 January 2021 about COVID-19 virus variants with Dr Mike Ryan, Executive Director of WHO Health Emergencies Programme, and Dr Maria Van Kerkhove, WHO Technical Lead on COVID-19. Questions from the audience were taken.
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carmattu.com carmattu.com
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Welcome! SIOP/CARMA Open Science Virtual Summer Series
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The overall focus of the workshop series is to introduce and teach attendees about open science practices that are widely believed to help researchers produce studies that are better planned and understood by all collaborators involved; more transparent and reproducible; and more accessible, useful, and impactful to the research and practice communities interested in the research. The virtual workshops will be hosted via CARMA’s resources (i.e., Zoom), and attendees can choose to attend any or all virtual workshops. By attending the summer series, you will learn critical principles and how-tos of open science practices that can be introduced into your research pipeline as well as learn about the perspectives of journal editors and associate editors hoping to encourage open science practices and enhance the robustness of our work (e.g., Lillian Eby of the Journal of Applied Psychology, Steven Rogelberg of the Journal of Business and Psychology).
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www.mdpi.com www.mdpi.com
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Citizen Science on Twitter: Using Data Analytics to Understand Conversations and Networks
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This paper presents a long-term study on how the public engage with discussions around citizen science and crowdsourcing topics. With progress in sensor technologies and IoT, our cities and neighbourhoods are increasingly sensed, measured and observed. While such data are often used to inform citizen science projects, it is still difficult to understand how citizens and communities discuss citizen science activities and engage with citizen science projects. Understanding these engagements in greater depth will provide citizen scientists, project owners, practitioners and the generic public with insights around how social media can be used to share citizen science related topics, particularly to help increase visibility, influence change and in general and raise awareness on topics. To the knowledge of the authors, this is the first large-scale study on understanding how such information is discussed on Twitter, particularly outside the scope of individual projects. The paper reports on the wide variety of topics (e.g., politics, news, ecological observations) being discussed on social media and a wide variety of network types and the varied roles played by users in sharing information in Twitter. Based on these findings, the paper highlights recommendations for stakeholders for engaging with citizen science topics.
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bhekisisa.org bhekisisa.org
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Why South Africa isn’t using the AstraZeneca jabs it bought
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After South Africa bought AstraZeneca vaccines from the Serum Institute of India, results from a small local study with only mild and moderate infections showed that the vaccine was not effective against the 501Y.V2 variant. South Africa sold its AstraZeneca vaccines in March despite World Health Organisation (WHO) advice that the jab should still be used in countries where new variants are circulating.Some experts, including the government’s ministerial advisory committee on vaccines, say the move is in line with South Africa’s evidence-based approach to COVID-19 decisions, while the Democratic Alliance and a group of scientists argue it’s a missed opportunity.
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www.researchsquare.com www.researchsquare.com
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Divergent trajectories of antiviral memory after SARS-Cov-2 infection
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is normally controlled by effective host immunity including innate, humoral and cellular responses. However, the trajectories and correlates of acquired immunity, and the capacity of memory responses months after infection to neutralise variants of concern - which has important public health implications - is not fully understood. To address this, we studied a cohort of 78 UK healthcare workers who presented in April to June 2020 with symptomatic PCR-confirmed infection or who tested positive during an asymptomatic screening programme and tracked virus-specific B and T cell responses longitudinally at 5-6 time points each over 6 months, prior to vaccination. We observed a highly variable range of responses, some of which - T cell interferon-gamma (IFN-γ) ELISpot, N-specific antibody waned over time across the cohort, while others (spike-specific antibody, B cell memory ELISpot) were stable. In such cohorts, antiviral antibody has been linked to protection against re-infection. We used integrative analysis and a machine-learning approach (SIMON - Sequential Iterative Modeling Over Night) to explore this heterogeneity and to identify predictors of sustained immune responses. Hierarchical clustering defined a group of high and low antibody responders, which showed stability over time regardless of clinical presentation. These antibody responses correlated with IFN-γ ELISpot measures of T cell immunity and represent a subgroup of patients with a robust trajectory for longer term immunity. Importantly, this immune-phenotype associates with higher levels of neutralising antibodies not only against the infecting (Victoria) strain but also against variants B.1.1.7 (alpha) and B.1.351 (beta). Overall memory responses to SARS-CoV-2 show distinct trajectories following early priming, that may define subsequent protection against infection and severe disease from novel variants.
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www.theguardian.com www.theguardian.com
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WHO voices concerns over Sputnik V Covid vaccine plant
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WHO reports issues with quality control data and test results as Slovakia announces it is offloading 160k doses
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www.cell.com www.cell.com
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The Neutrophil
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Neutrophils are immune cells with unusual biological features that furnish potent antimicrobial properties. These cells phagocytose and subsequently kill prokaryotic and eukaryotic organisms very efficiently. Importantly, it is not only their ability to attack microbes within a constrained intracellular compartment that endows neutrophils with antimicrobial function. They can unleash their effectors into the extracellular space, where, even post-mortem, their killing machinery can endure and remain functional. The antimicrobial activity of neutrophils must not be misconstrued as being microbe specific and should be viewed more generally as biotoxic. Outside of fighting infections, neutrophils can harness their noxious machinery in other contexts, like cancer. Inappropriate or dysregulated neutrophil activation damages the host and contributes to autoimmune and inflammatory disease. Here we review a number of topics related to neutrophil biology based on contemporary findings.
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www.bmj.com www.bmj.com
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Too little, too late: social media companies’ failure to tackle vaccine misinformation poses a real threat
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As the world looks to the new covid-19 vaccines with hope, there are major worries about how social media will affect uptake. Claire Wardle and Eric Singerman ask what the companies in charge should be doing to stem the misinformation tide
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assets.publishing.service.gov.uk assets.publishing.service.gov.uk
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SARS-CoV-2 variants of concern and variants under investigation in England
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There are 5 variants of concern and 8 variants under investigation (Table 1). VUI-21APR-02 (B.1.617.2) was escalated to a variant of concern on 6 May 2021 (VOC-21APR-02). It is assessed as having at least equivalent transmissibility to B.1.1.7 based on available data (moderate confidence). There are insufficient data currently to assess the potential for immune escape. There has been a steep recent increase in the number of cases identified (N=509 genomically confirmed) of this variant of concern in the UK, which includes both imported (n=157 confirmed after travel) and domestically-acquired cases. Postcodes of residence are most frequently identified as London and the North West. This technical briefing includes national overview data and surveillance updates for VUI-21APR-01 (B.1.617.1), VOC-21APR-02 (B.1.617.2) and VUI-21APR-03 (B.1.617.3), and a new clinical risk assessment for VOC-21APR-02 (B.1.617.2). The full update for each individual variant will be published in the next technical briefing and monthly thereafter.
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www.cdc.gov www.cdc.gov
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SARS-CoV-2–Associated Deaths Among Persons Aged <21 Years
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www.youtube.com www.youtube.com
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intuitive EPI - Table 2 Fallacy (Part 1)
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www.nature.com www.nature.com
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Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination
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psyarxiv.com psyarxiv.com
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Perceived vaccine safety over time in a vaccine hesitant sample: Impact of pausing due to safety concerns
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In the current effort to vaccinate as many people as possible against COVID-19, it has been suggested that events such as the pause in the use of the Janssen vaccine would have a large effect on perceptions of vaccine safety. Further, as vaccination rates slow, there is concern that hesitancy may be stable and difficult to change among those still unvaccinated. We examined both of these issues in our ongoing study of low-income participants. We modeled the intensive longitudinal data provided by 53 individuals. We found the negative, not statistically significant effect of the Janssen pause would be overwhelmed within weeks by the statistically significant increasing perceptions of safety across time. We also observed strong variability in vaccine hesitancy in many participants. Frequent reminders about vaccine availability might catch more people when they are less hesitant, helping increase vaccination rates.
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www.frontiersin.org www.frontiersin.org
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Exposure to COVID-19 Vaccine Hesitancy is As Impactful as Vaccine Misinformation in Inducing a Decline in Vaccination Intentions in New Zealand: Results from Pre-Post Between Groups Randomized Block Experiment
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www.cell.com www.cell.com
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Homeostatic functions of monocytes and interstitial lung macrophages are regulated via collagen domain-binding receptor LAIR1
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Myeloid cells encounter stromal cells and their matrix determinants on a continual basis during their residence in any given organ. Here, we examined the impact of the collagen receptor LAIR1 on myeloid cell homeostasis and function. LAIR1 was highly expressed in the myeloid lineage and enriched in non-classical monocytes. Proteomic definition of the LAIR1 interactome identified stromal factor Colec12 as a high-affinity LAIR1 ligand. Proteomic profiling of LAIR1 signaling triggered by Collagen1 and Colec12 highlighted pathways associated with survival, proliferation, and differentiation. Lair1−/− mice had reduced frequencies of Ly6C− monocytes, which were associated with altered proliferation and apoptosis of non-classical monocytes from bone marrow and altered heterogeneity of interstitial macrophages in lung. Myeloid-specific LAIR1 deficiency promoted metastatic growth in a melanoma model and LAIR1 expression associated with improved clinical outcomes in human metastatic melanoma. Thus, monocytes and macrophages rely on LAIR1 sensing of stromal determinants for fitness and function, with relevance in homeostasis and disease.
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www.nejm.org www.nejm.org
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Covid-19 Breakthrough Infections in Vaccinated Health Care Workers
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