for - health - heart - Beta-blocker/thiazide diuretic combos

health - heart - Beta-blocker/thiazide diuretic combos - This combo lowers the blood pressure by - removing excess water and salt from the body and - slowing the heart rate. - These only mask the symptoms CAUSED BY INSULIN RESISTANCE

Matthew seems to confirm a longheld belief i've had for a while (though, I think of it in differing ways). Mainly, that the world is ever changing, and that nothing is permanent (see permanent beta movement, as an example). If one wants to adapt to differing circumstances, one needs to learn.

Just a reminder... that all (stereo) audio... is spatial already...

Aren't these updates pushed over the air?

So now every time someone releases a software update, media is going to call it a recall? 🤔

Also, this is not currently working.

John Burn-Murdoch. (2021, November 25). Five quick tweets on the new variant B.1.1.529 Caveat first: Data here is very preliminary, so everything could change. Nonetheless, better safe than sorry. 1) Based on the data we have, this variant is out-competing others far faster than Beta and even Delta did 🚩🚩 https://t.co/R2Ac4e4N6s [Tweet]. @jburnmurdoch. https://twitter.com/jburnmurdoch/status/1463956686075580421

Prof. Shane Crotty. (2021, October 19). 1/ The regular vaccines give great booster responses against Delta and other variants This was first shown by Moderna, with “original recipe” vaccine booster, compare to Beta booster. Https://nature.com/articles/s41591-021-01527-y https://t.co/g7YDwGIURP [Tweet]. @profshanecrotty. https://twitter.com/profshanecrotty/status/1450489709050744833

Dr Dominic Pimenta [@DrDomPimenta]. (2021, December 15). An illustration of communicating risk with “less severe” variants: [Thread] Assume Omicron is 4x more transmissible than Delta. [1] Assume Omicron leads to 1/3 less admissions than Delta. [Figure below] Assume 1 in 100 cases of Delta are admitted to hospital. Https://t.co/XtnVwoOrUo [Tweet]. Twitter. https://twitter.com/DrDomPimenta/status/1471094002808242177

ReconfigBehSci [@SciBeh]. ‘RT @vikkypaedia: B.1.1.529 Seems to Have Gone from 0.1% to 50% in Just a Couple of Weeks, When It Took Delta Several Months to Achieve That…’. Tweet. Twitter, 26 November 2021. https://twitter.com/SciBeh/status/1464194450406752282.

Tao, K., Tzou, P. L., Nouhin, J., Gupta, R. K., de Oliveira, T., Kosakovsky Pond, S. L., Fera, D., & Shafer, R. W. (2021). The biological and clinical significance of emerging SARS-CoV-2 variants. Nature Reviews Genetics, 1–17. https://doi.org/10.1038/s41576-021-00408-x

Hirose, R., Itoh, Y., Ikegaya, H., Miyazaki, H., Watanabe, N., Yoshida, T., Bandou, R., Daidoji, T., & Nakaya, T. (2022). Differences in environmental stability among SARS-CoV-2 variants of concern: Omicron has higher stability [Preprint]. Microbiology. https://doi.org/10.1101/2022.01.18.476607

Paul Mainwood. (2021, November 29). @mroliverbarnes If it’s anything like Beta, then boosters should clobber it just fine. Https://t.co/LPX0GAXn1y [Tweet]. @PaulMainwood. https://twitter.com/PaulMainwood/status/1465263524104609792

Andreano, E., Paciello, I., Piccini, G., Manganaro, N., Pileri, P., Hyseni, I., Leonardi, M., Pantano, E., Abbiento, V., Benincasa, L., Giglioli, G., De Santi, C., Fabbiani, M., Rancan, I., Tumbarello, M., Montagnani, F., Sala, C., Montomoli, E., & Rappuoli, R. (2021). Hybrid immunity improves B cells and antibodies against SARS-CoV-2 variants. Nature, 1–7. https://doi.org/10.1038/s41586-021-04117-7

The BMJ on Twitter. (n.d.). Twitter. Retrieved 3 September 2021, from https://twitter.com/bmj_latest/status/1432056729743863810

Mahase, E. (2021). Covid-19: How many variants are there, and what do we know about them?: Video 1. BMJ, n1971. https://doi.org/10.1136/bmj.n1971

Nasreen, Sharifa, Hannah Chung, Siyi He, Kevin A. Brown, Jonathan B. Gubbay, Sarah A. Buchan, Deshayne B. Fell, et al. “Effectiveness of COVID-19 Vaccines against Variants of Concern in Ontario, Canada,” July 16, 2021. https://doi.org/10.1101/2021.06.28.21259420.

Callaway, E. (2021). Remember Beta? New data reveal variant’s deadly powers. Nature, d41586-021-02177–3. https://doi.org/10.1038/d41586-021-02177-3

Twitter. “Mia Malan on Twitter.” Accessed August 9, 2021. https://twitter.com/miamalan/status/1423531025313976322.

Tada, Takuya, Hao Zhou, Marie I. Samanovic, Belinda M. Dcosta, Amber Cornelius, Mark J. Mulligan, and Nathaniel R. Landau. “Comparison of Neutralizing Antibody Titers Elicited by MRNA and Adenoviral Vector Vaccine against SARS-CoV-2 Variants.” BioRxiv, July 19, 2021, 2021.07.19.452771. https://doi.org/10.1101/2021.07.19.452771.

What we call assessment is really an attempt to create a proxy indicator for what we call learning.

It seems weird to think of it that way; we don't really understand learning so we create tasks for students to complete in the hope those tasks somehow give us some insight into the thing that we don't really understand.

This article is ostensibly a response to the use of proctoring software in higher education.

But in order to do that properly the author has also delved into learning and assessment.

It's a well-written piece that questions some of our taken-for-granted assumptions around assessment.

This post articulates a lot of what I've been thinking about for the past 18 months or so, but it adds the additional concept of community integration.

Interestingly, this aligns with the early, tentative ideas around what the future of In Beta might look like as a learning community, rather than a repository of content.

Vaughan, A. (n.d.). Which covid-19 treatments work and how close are we to getting more? New Scientist. Retrieved 31 July 2020, from https://www.newscientist.com/article/2250176-which-covid-19-treatments-work-and-how-close-are-we-to-getting-more/

Me parece que el formulario debería ser sencillo y estar colocado en una sola página, en lugar de múltiples preguntas disgregadas a lo largo de una encuesta.

Me parece que el formulario actual está extremadamente dirigido a bibliotecarios, por ejemplo preguntando de qué tipo de bibliotecas se suscriben al manifiesto, con lo cual sesga fuertemente la posibilidad de instituciones de la sociedad civil e individuos que se vinculan a la misma.

Dado que se recolectan datos, como el usuario de Twitter, el formulario Manifiesto debería indicar una breve política de tratamiento de datos, algo como que los datos no serán ofrecidos a terceros sin permiso explícito y serán recolectados únicamente a fin de:

• mantenerte informado sobre el manifiesto,
• hacer el apoyo al mismo visible.
• contactarte para acciones relacionadas con los propósitos del manifiesto.

Full text summary: Beta 1 but not beta 2 is involved in REM sleep generation. High dose propranolol (which is not selective) practically obliterated REM sleep. Selective beta 1 agonism restored REM, while selective beta 2 agonism did not.

Thus, the effective pharmacological half life of phenoxybenzamine is roughly 1 day.

Alternatively, it could have been nocturnal hypotension that was causing the sleep disruption.

Surprisingly, beta-blockers, unlike alpha-blockers, appear to impair sleep.

Surprisingly, beta-blockers, unlike alpha-blockers, appear detrimental to sleep. I would speculate that this could be the result of a shift in autonomic tone, similar to how caffeine tends to lower heart rate.

This suggests that a beta 2 agonist may be appropriate for sleep.

Note: they appear to be talking about the number of dreams recalled (due to awakenings) rather than the actual number of dreams.

The question becomes, then, do beta blockers impair sleep when exogenous melatonin is administered concurrently?