292 Matching Annotations
  1. Dec 2023
      • for: climate crisis - debate - community action, climate crisis - discussion - community action, indyweb - curation example

      • discussion: effectiveness of community action to address climate crisis

        • This is a good discussion on the effectiveness of community action to address the climate crisis.
        • It offers a diverse range of perspectives that can all be mapped using SRG trailmark protocol and then data visualized within Indyweb via cytoscape
  2. Sep 2023
    1. this is just a hypothesis there's a thing called the unreasonable effectiveness of mathematics like why is it the case that you go off and you invent complex numbers and quaternions and do abstract algebra and somehow that has something 00:33:26 to say about the physical world still a mystery but there's an unreasonable effectiveness of deep learning there is no a priori reason why DNA and images and video and speech synthesis and fmri 00:33:40 should share a kind of universal shape but they do and I think that's telling us something very deep about the structure of the universe
      • for: unreasonable effectiveness of mathematics, emptiness, emptiness - unreasonable effectiveness of mathematics

      • comment

        • everything is an expression of emptiness
  3. May 2023
    1. They are efficiency and effectiveness. For memory systems, an effective system is one that gets the right answer every time no matter how long it takes you. And the efficient system is one that uses the least amount of resources like time, associations, dependent systems, etc. but it may not be that good at providing the correct answers.

      Efficiency and effectiveness measures for specific mnemonic systems may vary from person to person, so one should consider them with respect to their own practices. There may not be a single "right" or "correct" practice universally, but there could be one for everyone individually based on their own choices or preferences.

  4. Feb 2023
  5. Nov 2022
    1. The way you deal with your time outside of work is a little bit different, and so I’m going to put that aside.

      I wonder in what ways the time outside of work is managed differently. In the end, it is all about allocating your time to the uses you decide on.

  6. Oct 2022
    1. Das Produktivitätsproblem muss inbezug auf eine Relation gestellt werden,nämlich in bezug auf die Relation vonZettelkasten und Benutzer.

      "The productivity problem must be formulated in the context of a relation, in the relation of the ZK and its user." This holds generally I suppose, productivity notions must be placed in the context of the producer and their tools. Where the producer also is the one formulating what counts as productivity. Vgl [[A Practice for Note Card Systems Outputs – Interdependent Thoughts 20221023140227]] Reading this I realise I have little purpose for e.g. economic measures of general population productivity, and e.g. in my company staying away from using billable hours as measure for productivity (but struggling to find another way to have such conversations, about effectiveness perhaps more than productivity)

  7. Aug 2022
    1. Chadeau-Hyam, M., Wang, H., Eales, O., Haw, D., Bodinier, B., Whitaker, M., Walters, C. E., Ainslie, K. E. C., Atchison, C., Fronterre, C., Diggle, P. J., Page, A. J., Trotter, A. J., Ashby, D., Barclay, W., Taylor, G., Cooke, G., Ward, H., Darzi, A., … Elliott, P. (2022). SARS-CoV-2 infection and vaccine effectiveness in England (REACT-1): A series of cross-sectional random community surveys. The Lancet Respiratory Medicine, 0(0). https://doi.org/10.1016/S2213-2600(21)00542-7

    1. Kustin, T., Harel, N., Finkel, U., Perchik, S., Harari, S., Tahor, M., Caspi, I., Levy, R., Leschinsky, M., Dror, S. K., Bergerzon, G., Gadban, H., Gadban, F., Eliassian, E., Shimron, O., Saleh, L., Ben-Zvi, H., Amichay, D., Ben-Dor, A., … Stern, A. (2021). Evidence for increased breakthrough rates of SARS-CoV-2 variants of concern in BNT162b2 mRNA vaccinated individuals. MedRxiv, 2021.04.06.21254882. https://doi.org/10.1101/2021.04.06.21254882

    1. Lauring, A. S., Tenforde, M. W., Chappell, J. D., Gaglani, M., Ginde, A. A., McNeal, T., Ghamande, S., Douin, D. J., Talbot, H. K., Casey, J. D., Mohr, N. M., Zepeski, A., Shapiro, N. I., Gibbs, K. W., Files, D. C., Hager, D. N., Shehu, A., Prekker, M. E., Erickson, H. L., … Self, W. H. (2022). Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: Prospective observational study. BMJ, 376, e069761. https://doi.org/10.1136/bmj-2021-069761

  8. May 2022
  9. Apr 2022
    1. 🇺🇦 Meaghan Kall. (2022, January 27). NEW: 🏴󠁧󠁢󠁥󠁮󠁧󠁿 Vaccine effectiveness (symptomatic infection) data for BA.2 {Omicron’s more infectious sister} NO difference in VE between Omicron (BA.1) and BA.2 Possibly even higher VE for BA.2 but estimates overlap See full thread 🧵 from @freja_kirsebom https://t.co/bJ7uCn2cGV [Tweet]. @kallmemeg. https://twitter.com/kallmemeg/status/1486821549458001927

    1. Pérez-Then, E., Lucas, C., Monteiro, V. S., Miric, M., Brache, V., Cochon, L., Vogels, C. B. F., Cruz, E. D. la, Jorge, A., Santos, M. D. los, Leon, P., Breban, M. I., Billig, K., Yildirim, I., Pearson, C., Downing, R., Gagnon, E., Muyombwe, A., Razeq, J., … Iwasaki, A. (2021). Immunogenicity of heterologous BNT162b2 booster in fully vaccinated individuals with CoronaVac against SARS-CoV-2 variants Delta and Omicron: The Dominican Republic Experience (p. 2021.12.27.21268459). medRxiv. https://doi.org/10.1101/2021.12.27.21268459

    1. 🇺🇦 Meaghan Kall [@kallmemeg]. (2021, December 23). VACCINES Speaking of boosters, it’s not great news I’m afraid. Updated vaccine effectiveness analysis shows mRNA boosters beginning to wane from one month (week 5-9) for Omicron, and as low as 30-50% effective from 10 weeks post-booster. This effect is not seen with Delta. Https://t.co/g0tLxH3vLR [Tweet]. Twitter. https://twitter.com/kallmemeg/status/1474072056878804992

    1. Abu-Raddad, L. J., Chemaitelly, H., Ayoub, H. H., AlMukdad, S., Tang, P., Hasan, M. R., Coyle, P., Yassine, H. M., Al-Khatib, H. A., Smatti, M. K., Al-Kanaani, Z., Al-Kuwari, E., Jeremijenko, A., Kaleeckal, A. H., Latif, A. N., Shaik, R. M., Abdul-Rahim, H. F., Nasrallah, G. K., Al-Kuwari, M. G., … Bertollini, R. (2022). Effectiveness of BNT162b2 and mRNA-1273 COVID-19 boosters against SARS-CoV-2 Omicron (B.1.1.529) infection in Qatar (p. 2022.01.18.22269452). medRxiv. https://doi.org/10.1101/2022.01.18.22269452

  10. Mar 2022
    1. That’s all fine and well and good as long as you don’t have a crisis

      Systems that are too efficient will become brittle. Brittle systems collapse catastrophically when conditions vary too far from expectations. The only way to accommodate unforeseeable circumstances is to give up some efficiency for greater flexibility. This produces robust systems that endure where brittle systems collapse.

  11. Feb 2022
    1. ReconfigBehSci on Twitter: “RT @Gab_H_R: Effectiveness of mRNA-1273 against-Omicron and Delta variants ⚠️ The 3dose VE was 71.6% and 47.4% against Omicron infection (…” / Twitter. (n.d.). Retrieved February 22, 2022, from https://twitter.com/SciBeh/status/1496032262177136642

    1. Altarawneh, H. N., Chemaitelly, H., Hasan, M. R., Ayoub, H. H., Qassim, S., AlMukdad, S., Coyle, P., Yassine, H. M., Al-Khatib, H. A., Benslimane, F. M., Al-Kanaani, Z., Al-Kuwari, E., Jeremijenko, A., Kaleeckal, A. H., Latif, A. N., Shaik, R. M., Abdul-Rahim, H. F., Nasrallah, G. K., Al-Kuwari, M. G., … Abu-Raddad, L. J. (2022). Protection against the Omicron Variant from Previous SARS-CoV-2 Infection. New England Journal of Medicine, 0(0), null. https://doi.org/10.1056/NEJMc2200133

    1. Prof. Gavin Yamey MD MPH. (2022, January 21). His vax disinformation is at 34.55 in the video His full comments: “But people do not trust this vaccine. It’s not been through the normal trials, it’s a technology that’s not been proven as safe & effective, & now the data is coming in on the vaccine that’s showing that..” 1/3 [Tweet]. @GYamey. https://twitter.com/GYamey/status/1484668215825469445

  12. Jan 2022
    1. ReconfigBehSci. (2022, January 28). We’ve had at least 4 months of European governments tailoring policy to hospital capacity, not cases per se—So why are we still seeing arguments against the effectiveness of those policies based solely on cases, and not the actual target function? @AllysonPollock [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1487038050899222528

    1. Jennifer Cohn ✍🏻 📢. (2022, January 11). This chart says it all. If u got double vaccinated early on & are not yet boosted, ur effectively unvaccinated against Omicron infection. Thus, many adults & teens are effectively unvaccinated against infection. Kids got vaccinated recently & thus may be in a safer position. 1/ [Tweet]. @jennycohn1. https://twitter.com/jennycohn1/status/1481034404260581377

    1. Home

      Zuo, F., Abolhassani, H., Du, L., Piralla, A., Bertoglio, F., Campos-Mata, L. de, Wan, H., Schubert, M., Wang, Y., Sun, R., Cassaniti, I., Vlachiotis, S., Kumagai-Braesch, M., Andréll, J., Zhang, Z., Xue, Y., Wenzel, E. V., Calzolai, L., Varani, L., … Pan-Hammarström, Q. (2022). Heterologous immunization with inactivated vaccine followed by mRNA booster elicits strong humoral and cellular immune responses against the SARS-CoV-2 Omicron variant (p. 2022.01.04.22268755). https://doi.org/10.1101/2022.01.04.22268755

    1. Olson, S. M., Newhams, M. M., Halasa, N. B., Price, A. M., Boom, J. A., Sahni, L. C., Pannaraj, P. S., Irby, K., Walker, T. C., Schwartz, S. P., Maddux, A. B., Mack, E. H., Bradford, T. T., Schuster, J. E., Nofziger, R. A., Cameron, M. A., Chiotos, K., Cullimore, M. L., Gertz, S. J., … Randolph, A. G. (2022). Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents. New England Journal of Medicine, 0(0), null. https://doi.org/10.1056/NEJMoa2117995

    1. Carreño, J. M., Alshammary, H., Tcheou, J., Singh, G., Raskin, A., Kawabata, H., Sominsky, L., Clark, J., Adelsberg, D. C., Bielak, D., Gonzalez-Reiche, A. S., Dambrauskas, N., Vigdorovich, V., Group, P. S., Srivastava, K., Sather, D. N., Sordillo, E. M., Bajic, G., van Bakel, H., … Krammer, F. (2021). Activity of convalescent and vaccine serum against SARS-CoV-2 Omicron. Nature. https://doi.org/10.1038/d41586-021-03846-z

  13. Dec 2021
    1. Thiruvengadam, R., Awasthi, A., Medigeshi, G., Bhattacharya, S., Mani, S., Sivasubbu, S., Shrivastava, T., Samal, S., Rathna Murugesan, D., Koundinya Desiraju, B., Kshetrapal, P., Pandey, R., Scaria, V., Kumar Malik, P., Taneja, J., Binayke, A., Vohra, T., Zaheer, A., Rathore, D., … Garg, P. K. (2021). Effectiveness of ChAdOx1 nCoV-19 vaccine against SARS-CoV-2 infection during the delta (B.1.617.2) variant surge in India: A test-negative, case-control study and a mechanistic study of post-vaccination immune responses. The Lancet Infectious Diseases, S1473309921006800. https://doi.org/10.1016/S1473-3099(21)00680-0

  14. Nov 2021
    1. Thiruvengadam, R., Awasthi, A., Medigeshi, G., Bhattacharya, S., Mani, S., Sivasubbu, S., Shrivastava, T., Samal, S., Murugesan, D. R., Desiraju, B. K., Kshetrapal, P., Pandey, R., Scaria, V., Malik, P. K., Taneja, J., Binayke, A., Vohra, T., Zaheer, A., Rathore, D., … Garg, P. K. (2021). Effectiveness of ChAdOx1 nCoV-19 vaccine against SARS-CoV-2 infection during the delta (B.1.617.2) variant surge in India: A test-negative, case-control study and a mechanistic study of post-vaccination immune responses. The Lancet Infectious Diseases, 0(0). https://doi.org/10.1016/S1473-3099(21)00680-0

    1. Seth Trueger. (2021, July 21). If seatbelts work so well why do we have airbags crumple zones speed limits licensing road signs traffic lights road safety engineering ambulances EMTs trauma centers brakes https://t.co/6x29wCOlwp [Tweet]. @MDaware. https://twitter.com/MDaware/status/1417680529160294401

    1. Walter, E. B., Talaat, K. R., Sabharwal, C., Gurtman, A., Lockhart, S., Paulsen, G. C., Barnett, E. D., Muñoz, F. M., Maldonado, Y., Pahud, B. A., Domachowske, J. B., Simões, E. A. F., Sarwar, U. N., Kitchin, N., Cunliffe, L., Rojo, P., Kuchar, E., Rämet, M., Munjal, I., … Gruber, W. C. (2021). Evaluation of the BNT162b2 Covid-19 Vaccine in Children 5 to 11 Years of Age. New England Journal of Medicine, NEJMoa2116298. https://doi.org/10.1056/NEJMoa2116298

    1. This year, a United Nations regulation on vehicle cybersecurity came into force, obligating manufacturers to perform various risk assessments and report on intrusion attempts to certify cybersecurity readiness. The regulation will take effect for all vehicles sold in Europe from July 2024 and in Japan and South Korea in 2022.

      Global regulations for automotive cybersecurity being to emerge.

    2. Major software and hardware suppliers to the world’s manufacturers build in firewalls to ensure that such elements as infotainment systems are prevented from passing code to systems that regulate speed, steering and other critical functions.Vehicle electronic control units are being designed to send an alert if one system that normally never communicates with another suddenly tries to do so. And they’re also locked down, so that an attempt to inject new code will be thwarted.
    3. Cybersecurity companies must protect a vehicle in multiple ways. Threats include SIM cards carrying malicious code, faked over-the-air software updates, code sent from a smartphone to the vehicle, and vehicle sensors and cameras being tricked with wrong information.

      Multi-factor safety demands.

    4. The challenge may be even greater than securing the world’s airlines. According to a McKinsey & Company report on automotive cybersecurity, modern vehicles employ around 150 electronic control units and about 100 million lines of code; by 2030, with the advent of autonomous driving features and so-called vehicle-to-vehicle communication, the number of lines of code may triple.

      It will be difficult to ensure cybersecurity.

  15. Oct 2021
    1. Gil Feldman. (2021, October 26). @EricTopol Updated data from Israel. The booster works, without any doubt! Red (empty battery): Un-vax Light green (half battery): 2nd dose without the booster Green (full battery): With the booster https://t.co/HbZBvDMQs6 [Tweet]. @feldman_gil. https://twitter.com/feldman_gil/status/1452845319251767299

    1. Andreano, E., Paciello, I., Piccini, G., Manganaro, N., Pileri, P., Hyseni, I., Leonardi, M., Pantano, E., Abbiento, V., Benincasa, L., Giglioli, G., De Santi, C., Fabbiani, M., Rancan, I., Tumbarello, M., Montagnani, F., Sala, C., Montomoli, E., & Rappuoli, R. (2021). Hybrid immunity improves B cells and antibodies against SARS-CoV-2 variants. Nature, 1–7. https://doi.org/10.1038/s41586-021-04117-7

    1. Tartof, S. Y., Slezak, J. M., Fischer, H., Hong, V., Ackerson, B. K., Ranasinghe, O. N., Frankland, T. B., Ogun, O. A., Zamparo, J. M., Gray, S., Valluri, S. R., Pan, K., Angulo, F. J., Jodar, L., & McLaughlin, J. M. (2021). Effectiveness of mRNA BNT162b2 COVID-19 vaccine up to 6 months in a large integrated health system in the USA: A retrospective cohort study. The Lancet, 398(10309), 1407–1416. https://doi.org/10.1016/S0140-6736(21)02183-8

    1. Hulme, W. J., Williamson, E. J., Green, A., Bhaskaran, K., McDonald, H. I., Rentsch, C. T., Schultze, A., Tazare, J., Curtis, H. J., Walker, A. J., Tomlinson, L., Palmer, T., Horne, E., MacKenna, B., Morton, C. E., Mehrkar, A., Fisher, L., Bacon, S., Evans, D., … Goldacre, B. (2021). Comparative effectiveness of ChAdOx1 versus BNT162b2 COVID-19 vaccines in Health and Social Care workers in England: A cohort study using OpenSAFELY [Preprint]. Epidemiology. https://doi.org/10.1101/2021.10.13.21264937

    1. Higdon, M. M., Wahl, B., Jones, C. B., Rosen, J. G., Truelove, S. A., Baidya, A., Nande, A. A., ShamaeiZadeh, P. A., Walter, K. K., Feikin, D. R., Patel, M. K., Knoll, M. D., & Hill, A. L. (2021). A systematic review of COVID-19 vaccine efficacy and effectiveness against SARS-CoV-2 infection and disease [Preprint]. Epidemiology. https://doi.org/10.1101/2021.09.17.21263549

  16. Sep 2021
    1. David Dowdy on Twitter: “@NEJM joining the waning immunity debate. I’m going to push back a bit. Data from @UCSDHealth of vax effectiveness in health workers: 94% in June, 65% in July. Interpreted as ‘likely to be due to...delta and waning immunity over time, compounded by end of masking requirements.’ https://t.co/flDOfBbTs7” / Twitter. (n.d.). Retrieved September 2, 2021, from https://twitter.com/davidwdowdy/status/1433254675915157504?s=20

  17. Aug 2021
  18. Jul 2021
  19. Jun 2021
    1. Borobia, A. M., Carcas, A. J., Pérez-Olmeda, M., Castaño, L., Bertran, M. J., García-Pérez, J., Campins, M., Portolés, A., González-Pérez, M., García Morales, M. T., Arana-Arri, E., Aldea, M., Díez-Fuertes, F., Fuentes, I., Ascaso, A., Lora, D., Imaz-Ayo, N., Barón-Mira, L. E., Agustí, A., … Torvisco, J. M. (2021). Immunogenicity and reactogenicity of BNT162b2 booster in ChAdOx1-S-primed participants (CombiVacS): A multicentre, open-label, randomised, controlled, phase 2 trial. The Lancet, S0140673621014203. https://doi.org/10.1016/S0140-6736(21)01420-3

    1. Regev-Yochay, G., Amit, S., Bergwerk, M., Lipsitch, M., Leshem, E., Kahn, R., Lustig, Y., Cohen, C., Doolman, R., Ziv, A., Novikov, I., Rubin, C., Gimpelevich, I., Huppert, A., Rahav, G., Afek, A., & Kreiss, Y. (2021). Decreased Infectivity Following BNT162b2 Vaccination. SSRN Electronic Journal. https://doi.org/10.2139/ssrn.3815668

    1. Thompson, M. G., Burgess, J. L., Naleway, A. L., Tyner, H. L., Yoon, S. K., Meece, J., Olsho, L. E. W., Caban-Martinez, A. J., Fowlkes, A., Lutrick, K., Kuntz, J. L., Dunnigan, K., Odean, M. J., Hegmann, K. T., Stefanski, E., Edwards, L. J., Schaefer-Solle, N., Grant, L., Ellingson, K., … Gaglani, M. (2021). Interim Estimates of Vaccine Effectiveness of BNT162b2 and mRNA-1273 COVID-19 Vaccines in Preventing SARS-CoV-2 Infection Among Health Care Personnel, First Responders, and Other Essential and Frontline Workers—Eight U.S. Locations, December 2020–March 2021. MMWR. Morbidity and Mortality Weekly Report, 70(13), 495–500. https://doi.org/10.15585/mmwr.mm7013e3

    1. Hall, V. J., Foulkes, S., Saei, A., Andrews, N., Oguti, B., Charlett, A., Wellington, E., Stowe, J., Gillson, N., Atti, A., Islam, J., Karagiannis, I., Munro, K., Khawam, J., Group, T. S. S., Chand, M. A., Brown, C., Ramsay, M. E., Bernal, J. L., & Hopkins, S. (2021). Effectiveness of BNT162b2 mRNA Vaccine Against Infection and COVID-19 Vaccine Coverage in Healthcare Workers in England, Multicentre Prospective Cohort Study (the SIREN Study) (SSRN Scholarly Paper ID 3790399). Social Science Research Network. https://doi.org/10.2139/ssrn.3790399

  20. May 2021
    1. Eric Topol. (2021, May 1). Downgrading the concern on B.1.617, the poorly named ‘double mutant’—98% effectiveness of mRNA vaccine in an Israeli outbreak @CT_Bergstrom https://t.co/tGbuwPUmAL —Lab studies: Minimal immune evasion, expected full protection from vaccine @GuptaR_lab https://t.co/AIp24G0ROK https://t.co/AK20UWlDBD [Tweet]. @EricTopol. https://twitter.com/EricTopol/status/1388539223230140422

    1. Adam Kucharski. (2021, April 14). If populations are highly vaccinated, we’d expect a higher proportion of future cases to have been previously vaccinated (because by definition, there aren’t as many non-vaccinated people around to be infected). But what sort of numbers should we expect? A short thread... 1/ [Tweet]. @AdamJKucharski. https://twitter.com/AdamJKucharski/status/1382242089673617417

    1. Hall, V. J., Foulkes, S., Saei, A., Andrews, N., Oguti, B., Charlett, A., Wellington, E., Stowe, J., Gillson, N., Atti, A., Islam, J., Karagiannis, I., Munro, K., Khawam, J., Chand, M. A., Brown, C. S., Ramsay, M., Lopez-Bernal, J., Hopkins, S., … Heeney, J. L. (2021). COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): A prospective, multicentre, cohort study. The Lancet, 0(0). https://doi.org/10.1016/S0140-6736(21)00790-X

  21. Apr 2021
    1. The Principle of Effectiveness: Devote time only to what brings you closer towards achieving your organization’s overall objectives, so that you can make the best use of your limited time, energy and resources.

      Yes, and reduce WIP and get to done quick!