38 Matching Annotations
  1. Last 7 days
  2. Aug 2020
    1. Clausen, T. M., Sandoval, D. R., Spliid, C. B., Pihl, J., Painter, C. D., Thacker, B. E., Glass, C. A., Narayanan, A., Majowicz, S. A., Zhang, Y., Torres, J. L., Golden, G. J., Porell, R., Garretson, A. F., Laubach, L., Feldman, J., Yin, X., Pu, Y., Hauser, B., … Esko, J. D. (2020). SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. BioRxiv, 2020.07.14.201616. https://doi.org/10.1101/2020.07.14.201616

    1. Amanat, F., White, K. M., Miorin, L., Strohmeier, S., McMahon, M., Meade, P., Liu, W.-C., Albrecht, R. A., Simon, V., Martinez‐Sobrido, L., Moran, T., García‐Sastre, A., & Krammer, F. (2020). An In Vitro Microneutralization Assay for SARS-CoV-2 Serology and Drug Screening. Current Protocols in Microbiology, 58(1), e108. https://doi.org/10.1002/cpmc.108

  3. Jul 2020
    1. That does not mean that there is infectious virus present. (This distinction has confused a great number of reports about the persistence of the virus on surfaces as well). We still don’t know how long infected patients (symptomatic and asymptomatic) are shedding infectious virus – those are far harder data points to obtain than just detecting viral RNA.
    1. Sapoval, N., Mahmoud, M., Jochum, M. D., Liu, Y., Elworth, R. A. L., Wang, Q., Albin, D., Ogilvie, H., Lee, M. D., Villapol, S., Hernandez, K., Berry, I. M., Foox, J., Beheshti, A., Ternus, K., Aagaard, K. M., Posada, D., Mason, C., Sedlazeck, F. J., & Treangen, T. J. (2020). Hidden genomic diversity of SARS-CoV-2: Implications for qRT-PCR diagnostics and transmission. BioRxiv, 2020.07.02.184481. https://doi.org/10.1101/2020.07.02.184481

  4. Jun 2020
    1. Starr, T. N., Greaney, A. J., Hilton, S. K., Crawford, K. H., Navarro, M. J., Bowen, J. E., Tortorici, M. A., Walls, A. C., Veesler, D., & Bloom, J. D. (2020). Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding [Preprint]. Microbiology. https://doi.org/10.1101/2020.06.17.157982

    1. Marshall, J. C., Murthy, S., Diaz, J., Adhikari, N., Angus, D. C., Arabi, Y. M., Baillie, K., Bauer, M., Berry, S., Blackwood, B., Bonten, M., Bozza, F., Brunkhorst, F., Cheng, A., Clarke, M., Dat, V. Q., de Jong, M., Denholm, J., Derde, L., … Zhang, J. (2020). A minimal common outcome measure set for COVID-19 clinical research. The Lancet Infectious Diseases, S1473309920304837. https://doi.org/10.1016/S1473-3099(20)30483-7

    1. there’s a bill tiptoeing through the U.S. Congress that could inflict the backdoor virus that law enforcement agencies have been trying to inflict on encryption for years... The choice for tech companies comes down to weakening their own encryption and endangering the privacy and security of all their users, or foregoing protections and potentially facing liability in a wave of lawsuits.
    1. Putting that risk more simply, the EARN-IT bill is cleverly leaving it to the tech platforms to keep themselves safe—there would be little option other than some form of access to encrypted content, even though it would not be specified in law. Sophos describes this as “the backdoor virus that law enforcement agencies have been trying to inflict on encryption for years.”
  5. May 2020
    1. to concentrate the viruses, the 1‐l aliquot was acidified with 1 mol l−1 acetic acid to pH ~3·0 and then viruses were filtered onto a 47‐mm, 0·45‐μm HA negatively charged nitrocellulose filter
  6. Apr 2020
  7. Apr 2019
    1. YouTube doesn’t give an exact recipe for virality. But in the race to one billion hours, a formula emerged: Outrage equals attention.

      Talk radio has had this formula for years and they've almost had to use it to drive any listenership as people left radio for television and other media.

      I can still remember the different "loudness" level of talk between Bill O'Reilly's primetime show on Fox News and the louder level on his radio show.

  8. May 2017
    1. Cindy A. Buckmaster: Animal research Is a labor of love for animals and people

      This page was analyzed on May 5, 2017 and was found to have low virality and impact. While the content may be either true or false, it is nnot moving through the network in the way we see hoaxes or clickbait move.

  9. Mar 2017
    1. The person is often only aware of feeling of constraint. We pick away at those constraints little by little. Meaningful time spent with one person has a viral effect on other students who are witnesses to the uniquely meaninful dialogue. Such moments of connection become virtuous, viral messages.

      meaningful connection

      constraint meaningless

      WHY

      KEY

      https://vimeo.com/195637079