- Oct 2020
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www.plymouth.edu www.plymouth.edu
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Cholesterol
This is a fat-like substance found in every single cell in the body. It aides the body to create hormones, vitamin D, and it also helps to digest food. Many dairy products are rich in Cholesterol which can be harmful if intaking high levels of it. This is due to fat deposits in the blood vessels which increases the risks of heart disease.
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- Sep 2020
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CNN, A. K. (n.d.). Fewer than 10% in the US have antibodies to the novel coronavirus. CNN. Retrieved September 29, 2020, from https://www.cnn.com/2020/09/25/health/coronavirus-antibodies-dialysis-patients/index.html
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www.sciencenews.org www.sciencenews.org
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A Brazilian city devastated by COVID-19 may have reached herd immunity. (2020, September 24). Science News. https://www.sciencenews.org/article/coronavirus-covid-19-brazil-city-manaus-herd-immunity
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www.fda.gov www.fda.gov
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Commissioner, O. of the. (2020, September 23). Coronavirus (COVID-19) Update: FDA Authorizes First Point-of-Care Antibody Test for COVID-19. FDA; FDA. https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-first-point-care-antibody-test-covid-19
Tags
- blood sample
- public health response
- serology
- is:news
- protection
- point-of-care
- is:webpage
- strategy
- COVID-19
- lang:en
- antibody test
- FDA
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URL
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www.healthline.com www.healthline.com
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Blood Thinners, Blood Pressure Meds May Improve COVID-19 Survival Rate. (2020, August 27). Healthline. https://www.healthline.com/health-news/blood-thinners-blood-pressure-meds-may-improve-covid-19-survival-rate
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- Aug 2020
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www.thehindubusinessline.com www.thehindubusinessline.com
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Awasthi, P. (n.d.). Scientists find five blood molecules linked to severe Covid-19 outcome in patients. @businessline. Retrieved August 20, 2020, from https://www.thehindubusinessline.com/news/science/scientists-find-five-blood-molecules-linked-to-severe-covid-19-outcome-in-patients/article32302700.ece
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- Jul 2020
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www.newscientist.com www.newscientist.com
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Vaughan, A. (n.d.). Which covid-19 treatments work and how close are we to getting more? New Scientist. Retrieved 31 July 2020, from https://www.newscientist.com/article/2250176-which-covid-19-treatments-work-and-how-close-are-we-to-getting-more/
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- Jun 2020
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www.theguardian.com www.theguardian.com
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editor, I. S. S. (2020, May 17). Doctors raise hopes of blood test for children with coronavirus-linked syndrome. The Guardian. https://www.theguardian.com/science/2020/may/17/possible-breakthrough-in-coronavirus-related-syndrome-in-children
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elemental.medium.com elemental.medium.com
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Smith, Dana G. ‘Coronavirus May Be a Blood Vessel Disease, Which Explains Everything’. Medium, 31 May 2020. https://elemental.medium.com/coronavirus-may-be-a-blood-vessel-disease-which-explains-everything-2c4032481ab2.
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- May 2020
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www.washingtonpost.com www.washingtonpost.com
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health, L. B. closeLenny B. covering, & medicineEmailEmailBioBioFollowFollow. (n.d.). More evidence emerges on why covid-19 is so much worse than the flu. Washington Post. Retrieved May 31, 2020, from https://www.washingtonpost.com/health/more-evidence-emerges-on-why-covid-19-is-so-much-worse-than-the-flu/2020/05/21/e7814588-9ba5-11ea-a2b3-5c3f2d1586df_story.html
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www.gov.uk www.gov.uk
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Sero-surveillance of COVID-19. (n.d.). GOV.UK. Retrieved May 27, 2020, from https://www.gov.uk/government/publications/national-covid-19-surveillance-reports/sero-surveillance-of-covid-19
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- Apr 2020
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Wölfel, R., Corman, V.M., Guggemos, W. et al. Virological assessment of hospitalized patients with COVID-2019. Nature (2020). https://doi.org/10.1038/s41586-020-2196-x
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accessmedicine.mhmedical.com accessmedicine.mhmedical.com
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The final stages of this sequence are caused by blood accumulation that forces the temporal lobe medially, with resultant compression of the third cranial nerve and eventually the brain stem.
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- Jan 2020
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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RESULTS: In the hypothyroid state, the plasma volume measured by dilution of 125I-albumin (APV) was higher than the calculated plasma volume (CPV) from packed red cell mass, suggesting an extravascular escape of albumin. After substitutive therapy, the CPV showed a statistical increase (P < 0.05), whereas APV remained unchanged. Both ERPF and GFR increased after thyroxine therapy (p < 0.05). In the subclinical group, blood volumes and renal function were similar to those found in the other group of patients when in the euthyroid state.
If this holds true, I'd expect rapid blood volume expansion from thyroid hormone. I'm also interested in whether thyroid hormone stimulates the production of albumin, given its anabolic properties.
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Thyrotoxicosis creates a hyperdynamic circulatory state because of a marked fall in peripheral vascular resistance and associated increase in venous return, increased total blood volume, increased cardiac contractility and heart rate.
If the mechanism is really the same as alpha blockers, then the blood volume expansion may be expected to be similar in constitution. However, I would expect more red blood cells in thyroid mediated volume expansion compared to alpha blockers. The reason, obviously, is because of the increased oxygen demand from thyroid hormone.
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- Oct 2019
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www.theregister.co.uk www.theregister.co.uk
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A highly interesting article where a well-known company prefers blood money to allowing employees to talk about politics. This is capitalism at its core: all profit, no empathy.
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GitLab, a San Francisco-based provider of hosted git software, recently changed its company handbook to declare it won't ban potential customers on "moral/value grounds," and that employees should not discuss politics at work.
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If you can see how people might respond to IBM, infamous for providing technology that helped the Nazis in World War II, saying, "Who has time to look into the source of this hard German currency?" you can imagine how GitLab's policy amendment has been received.
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- Aug 2019
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www.press.jhu.edu www.press.jhu.edu
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He once showed me a Sanskrit volume handwritten in human blood: “You know, Greg, all great writers must work this way.”
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- Mar 2019
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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SBP, DBP, RR, and weight did not change following T3 administration
Liothyronine does not raise blood pressure despite the rise in heart rate. The reason that respiratory rate (RR) was not changed may be because the increased cardiac output compensates for the increased oxygen demand.
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- Feb 2019
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accessmedicine.mhmedical.com accessmedicine.mhmedical.com
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Office-based devices that permit multiple automated measurements after a pre-programmed rest period produce blood pressure readings that are independent of digit preference bias and the “white coat” phenomenon (where blood pressure is elevated in the clinic but normal at home)
This is a great recommendation.
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www.npr.org www.npr.org
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Blood Orange
What feminism is --- this first song gave me chills!! So good!
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- Dec 2018
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www.nature.com www.nature.com
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Insights into imprinting from parent-of-origin phased methylomes and transcriptomes
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Annotators
URL
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- Aug 2018
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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CONCLUSIONS: These findings suggest that higher standing BP is a biomarker that helps identify persons with combat PTSD who are likely to benefit from prazosin. These results also are consistent with α1AR activation contributing to PTSD pathophysiology in a subgroup of patients.
This is precisely the results I would expect. However, I completely disagree with their interpretation.
People with high blood pressure (BP) can tolerate a reduction in BP without instigating compensatory mechanisms. People with normal or low BP would invoke compensation by the sympathetic nervous system in response to alpha blockade. This would counteract the depressant effects of adrenergic antagonism. Indeed, adrenaline and noradrenaline elevate in response to standing, which I find to be an obvious prediction. Thus, the lack of benefit from prazosin in these subjects may be mediated by an increase in adrenergic receptor activation other than the apha1-adrenoreceptor; in particular, the beta-adrenergic receptors are likely at fault. Propranolol, a beta-blocker, is used for PTSD, so this mechanism seems well substantiated.
The study apparently found benefit for patients with BP over 110 (with more benefit for higher BP). Thus, I would conclude that systolic pressure below 110 induce compensation.
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www.arenawaterinstinct.com www.arenawaterinstinct.com
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Graph 2 shows the trend for the diastolic pressure.
Post-exercise, diastolic pressure is higher than baseline; compression garments exaggerate this effect
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Graph 1 shows the systolic pressure data (x-axis in mmHg). It can be noted that the test subjects start from an equal baseline condition, but after performing the swimming test the athletes not wearing the costume in the first control (20-30 mins) have an average systolic pressure that has dropped to approximately 90 mmHg.
Thus, compression garments may prevent circumstantial hypotension. In this case, one possibility is that the compression is delivering blood to the heart that would otherwise be shunted to the skin for heat dissipation.
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academic.oup.com academic.oup.com
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Table 2
These trained athletes have a BP of about 100/60 at rest. This is substantially lower than the roughly 120/80 BP that I've seen elsewhere. This likely limits the drop in BP seen post-exercise.
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Hypertension also affects brain capillary density. Similar to the peripheral microcirculation, hypertension causes rarefaction (decrease in number) of capillaries and impaired microvessel formation that can increase vascular resistance
This is important because it implies that syncope or incomplete syncope as a result of vasodilators may not be dependent on actual blood pressure. It means that it is theoretically possible that vasodilators will acutely increase blood flow despite a drop in BP, depending on the body's level of compensation via increased cardiac output.
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Annotators
URL
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Although atenolol had no effect on subjective measures of sleep this hydrophilic drug also reduced REM frequency, suggesting that either it has some central effect, or that REM reduction is due to a peripheral 'shielding' effect.
Alternatively, it could have been nocturnal hypotension that was causing the sleep disruption.
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- Dec 2017
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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A beneficial impact of the fat quality on insulin sensitivity is not seen in individuals with a high fat intake (> 37E%).
This is likely do to the reduced carbohydrate intake rather than increased fat intake. Since carbohydrates generally insulin sensitivity, it's likely that this additional insulin resistance is acting as a confounder (as well as, presumably, a standard deviation widener). Thus, I would expect similar results during hypocaloric carbohydrate restriction.
Tags
- diabetes insulin sensitivity resistance blood sugar
- saturated fatty acid fat LCSFAs unsaturated ceramide intramuscular triglycerides intramyocellular lipid
- fatty acid / fat / LCSFA(s) /
- diabetes / insulin sensitivity/resistance / blood sugar
- diet health lifestyle disease prevention and reversal food nutrients nutrition eat
- research note
Annotators
URL
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- Nov 2017
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www.npr.org www.npr.org
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While the title of this report does not really imply anything to contradict the results of the testing of the theory, the content of the report itself leaves room for interpretation as to what these results mean and who it applies to. The main study referenced conducted by the University of Rome (Loffredo) does show that the participants who were given dark chocolate showed a higher acute result than those who were given milk chocolate, their study was made up of a small group of 20. It could also be pointed out that they did not establish a portion of their group who were tested without the ingestion of chocolate to establish a better baseline for their results. Participants endurance on a treadmill was used to measure the effects of the chocolate, but there is no indication of how or if the participants increase in ambulatory movement, or having “warmed up” with their baseline test day may have contributed to the improved results after the chocolate was administered. Another point to note is where the author mentions a previous report she submitted (Aubrey) covering the similarity of the results of the chocolate study to a study on the affects of meditation on the body. While the result may be considered similar, the way the results were achieved were very different. The wording in the studies referenced for the benefits of meditation reflect a psychological improvement as a means for a physical response, while the chocolate experiment was testing a chemical application for a physiological response. This article, although not wrong or misrepresenting the study, simplifies much of the work and applies it to the general public. The author does manage to address that the study is incomplete, as an afterthought and could easily be interpreted as having less weight than the argument for chocolate treatment by simply being under represented or under explained. Further investigation is definitely needed to understand the “how and why” of the affects of chocolate/polyphenols on our bodies before we can set any sort of prescription in place. The study would need to be much more comprehensive or added to others that test this same result on other demographics to determine if the affects can be replicated on everyone, or to narrow down if they only get this result with those who have PAD.
Aubrey, A. (2008, August 21). To Lower Blood Pressure, Open Up And Say 'Om'. Retrieved November 09, 2017, from https://www.npr.org/2008/08/21/93796200/to-lower-blood-pressure-open-up-and-say-om MPH, M. G. (2014, March 01). Meditation for Psychological Stress and Well-being. Retrieved November 09, 2017, from https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/1809754 Loffredo, L., Perri, L., Catasca, E., Pignatelli, P., Brancorsini, M., Nocella, C., . . . Violi, F. (2014, August 21). Dark Chocolate Acutely Improves Walking Autonomy in Patients With Peripheral Artery Disease. Retrieved November 09, 2017, from http://jaha.ahajournals.org/content/3/4/e001072
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- Oct 2017
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www.lifeextension.com www.lifeextension.com
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Beta blockers have long been associated with sleep disturbances such as difficulty falling asleep, staying asleep, and insomnia. They have been shown to reduce the production of melatonin via specific inhibition of beta-1 adrenergic receptors. Melatonin is a hormone secreted by the pineal gland in the brain, and helps in maintaining normal circadian rhythms.6,20-21 People with hypertension already have a lower melatonin production rate than those with normal blood pressure.22
The question becomes, then, do beta blockers impair sleep when exogenous melatonin is administered concurrently?
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- Jul 2017
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www.musikexpress.de www.musikexpress.de
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- Jun 2017
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www.offiziellecharts.de www.offiziellecharts.de
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- Mar 2017
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www.who.int www.who.int
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In patients receiving diuretic therapy symptomatichypotension may occur following the initial dose of proposed FDC, particularly due to volume/salt depletion with diuretic therapy
We have found different results in the research that we have done.
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- Nov 2016
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hypothes.is hypothes.is
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Two new molecular catalysts of water oxidation have been synthesized by a team of brilliant scientists from the U.S. Department of Energy’s Brookhaven National Laboratory. These new molecular catalysts – complexes of ruthenium which are surrounded by the binding molecules, and they contain phosphonate groups.
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- Jul 2016
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wn.rsarchive.org wn.rsarchive.org
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spiritual senses of the occultist as are externally perceptible colors to the physical eye. This etheric body can actually be seen by the clairvoyant. It is the principle which calls the inorganic materials into life, which, summoning them from their lifeless condition, weaves them into the thread of life's garment.
This reminds me of the diabetes and heart disease epidemic. If through forced choice you can engender a species of people to change the make up of their blood through outside chemicals and OVER FEEDING everyone sugar rendering most people diabetic you can in essence control the emerging medical needs of a society dependent on new forms of health care and medicines. The obama care state.
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