591 Matching Annotations
  1. Sep 2022
  2. Feb 2022
    1. Understanding the effects of introducing Solar PV and how it can affect “Power Factor” on complex Industrial/Commercial sites
  3. Jan 2022
  4. Dec 2021
  5. Nov 2021
  6. Aug 2021
  7. Jul 2021
    1. In order to use Z-Wave, Zigbee or other integrations that require access to devices, you need to map the appropriate device into the container.
  8. Jun 2021
  9. Oct 2020
    1. Future kernel updates would require the updated kernels to be signed again, so it makes sense to put the signing commands in a script that can be run at a later date as necessary. A sample script /root/module-signing/sign-vbox-modules is given below.
  10. Jul 2020
    1. A shell script to automate the retrieval and installation of the Oracle (Sun) Java Runtime Environment
  11. May 2020
  12. Jan 2020
  13. Nov 2019
    1. CompizConfig Settings Manager's Place windows plug-in which will allow an application that isn't running to open on its particular workspace at its pre-defined X-Y coordinate,
  14. Jul 2019
  15. May 2019
  16. Feb 2019
  17. Jan 2019
  18. Dec 2018
  19. Nov 2018
  20. Oct 2018
  21. Sep 2018
    1. HOMER
    2. Target enhancers are identified by leave-one-ou

      Likelihood ratio test as in ISMARA?

    3. ridge regressio
    4. centered and scale

      Likely centering and scaling (by SD) rows, i.e., across samples.

    5. motifs without any hits in the supplied sequencesand motifs mapping to transcription factors with low expression(default threshold: 1 normalized read per kilobase) are remove


    6. motif matrix is centered

      Could mean double-centered, or row- or column-centered. Rows correspond to enhancers, columns to motifs. Centering columns makes sense; rows not so much.

    7. Motif search, calculation of motif activities, and target prediction
    1. Unlike simple k-mer searching, these methods were designed to predict individual RBP binding sites. They go beyond the motif content alone, for instance by taking into account site accessibility (Li et al. 2010; Zhang et al. 2013) or clustering (Akerman et al. 2009; Zhang et al. 2013).

      Suggests that RBPmap is a good choice, provided one uses the weighted rank score accounting for clustering and the conservation filter. mCarts by Zhang et al. applied to the ENCODE CLIP data would complement RBPmap, but what would be even better is if ENCODE had already applied it to their data and can provide the binding site predictions.

    2. Estimating the prevalence of functional exonic splice regulatory information
  22. Aug 2018
    1. RHEL mount hangs: nfs: server [...] not responding, still trying
  23. Jul 2018
    1. repeat expansion at IIL1 leads to increased accumulation of 24-nt siRNAs in a temperature-dependent manner that correlates with the iil phenotype. We show that DCL3 and other components of the RNA-dependent DNA methylation (RdDM) pathway are essential for this siRNA-directed epigenetic gene silencing
  24. Jun 2018
    1. Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs

      Queuosine metabolite necessary for DNMT2-induced tRNA modification; salvaged from bacteria of microbiome

  25. May 2018
    1. one level is chosen as the “reference”, and its mean behaviour is represented by the intercept. Each column of the resulting matrix represents the difference between the mean of one level and this reference level
  26. Apr 2018
    1. caffeine caused a significant decrease of PTH secretion and PTH gene expression. This decrease occurred in parallel with a decrease of the intracellular cAMP level, protein kinase A activity, and ADORA1 gene expression
    1. chronic administration of caffeine could lead to negative calcium balance when there is an impaired ability to increase the efficiency of calcium absorption. Such a situation exists in elderly human subjects