Aortic dissection typically presents acutely with sudden, severe tearing chest or back pain, often described as lancinating in quality. [5-6] Approximately 50% of patients with thoracic aortic aneurysm may progress to dissection without timely intervention. [5] In contrast, thoracic aortic aneurysm is usually asymptomatic and discovered incidentally during physical examination or imaging for other indications. [5]
4 Matching Annotations
- Mar 2026
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accessmedicine.mhmedical.com accessmedicine.mhmedical.com
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- Recent evidence suggests that inflammatory biomarkers may aid differentiation. The neutrophil-to-lymphocyte ratio (NLR) shows high diagnostic accuracy for distinguishing dissection from controls (AUC 0.933), while the fibrinogen-to-d-dimer ratio best differentiates dissection from aneurysm (AUC 0.898, sensitivity 77%, specificity 84%). [10] D-dimer levels below 500 ng/mL make acute aortic syndrome unlikely in low-risk patients
- CT angiography is the imaging modality of choice for differentiating these conditions in the emergency setting, with very high sensitivity and specificity for acute aortic syndromes
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URL
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- Oct 2021
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www.cell.com www.cell.com
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Burn, G. L., Foti, A., Marsman, G., Patel, D. F., & Zychlinsky, A. (2021). The Neutrophil. Immunity, 54(7), 1377–1391. https://doi.org/10.1016/j.immuni.2021.06.006
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- Apr 2018
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www.nature.com www.nature.com
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Genome-scale DNA methylome and transcriptome profiling of human neutrophils
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- Mar 2018
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academic.oup.com academic.oup.com
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Neutrophils in cardiovascular disease
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