- Nov 2023
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docdrop.org docdrop.org
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there's a microbe in the mouth called fusobacterium nucleotide it over proliferates it's okay to have normally but it over proliferates when 01:28:39 you have bleeding gums gingivitis or periodontitis where it then enters the bloodstream this is called translocation and colonize the colon and the evidence is very good it is a principal cause of 01:28:52 colon cancer colon cancer starts in the mouth incredibly and doesn't get there by swallowing gets her through the bloodstream translocation
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for:holistic medicine - example - oral microbiome and colon cancer, oral microbiome - colon cancer, bleeding gums - colon cancer, gingivitus - colon cancer, periodontitis - colon cancer, bloodstream translocation, complexity - example - human body - colon cancer - oral microbiome
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comment
- colon cancer starts in the mouth!
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references
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Oral-Intestinal Microbiota in Colorectal Cancer: Inflammation and Immunosuppression (2022)
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824753/
- Abstract
- It is widely recognized that microbial disorders are involved in the pathogenesis of many malignant tumors.
- The oral and intestinal tract are two of the overriding microbial habitats in the human body. Although they are anatomically and physiologically continuous, belonging to the openings at both ends of the digestive tract, the oral and intestinal microbiome do not cross talk with each other due to a variety of reasons, including
- intestinal microbial colonization resistance and
- chemical barriers in the upper digestive tract.
- However, this balance can be upset in certain circumstances, such as
- disruption of colonization resistance of gut microbes,
- intestinal inflammation, and
- disruption of the digestive tract chemical barrier.
- Evidence is now accruing to suggest that the oral microbiome can colonize the gut, leading to dysregulation of the gut microbes.
- Furthermore, the oral-gut microbes create an
- intestinal inflammatory and
- immunosuppressive microenvironment
- conducive to
- tumorigenesis and
- progression of colorectal cancer (CRC).
- Here, we review
- the oral to intestinal microbial transmission and
- the inflammatory and immunosuppressive microenvironment, induced by oral-gut axis microbes in the gut.
- A superior comprehension of the contribution of the oral-intestinal microbes to CRC provides new insights into the prevention and treatment of CRC in the future.
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Insights into oral microbiome and colorectal cancer – on the way of searching new perspectives (2023)
- https://www.frontiersin.org/articles/10.3389/fcimb.2023.1159822/full
- Abstract
- Microbiome is a keystone polymicrobial community that coexist with human body in a beneficial relationship.
- These microorganisms enable the human body to maintain homeostasis and take part in mechanisms of defense against infection and in the absorption of nutrients.
- Even though microbiome is involved in physiologic processes that are beneficial to host health, it may also cause serious detrimental issues.
- Additionally, it has been proven that bacteria can migrate to other human body compartments and colonize them even although significant structural differences with the area of origin exist.
- Such migrations have been clearly observed when the causes of genesis and progression of colorectal cancer (CRC) have been investigated.
- It has been demonstrated that the oral microbiome is capable of penetrating into the large intestine and cause impairments leading to dysbiosis and stimulation of cancerogenic processes.
- The main actors of such events seem to be oral pathogenic bacteria belonging to the red and orange complex (regarding classification of bacteria in the context of periodontal diseases), such as
- Porphyromonas gingivalis and
- Fusobacterium nucleatum respectively,
- which are characterized by significant amount of cancerogenic virulence factors.
- Further examination of oral microbiome and its impact on CRC may be crucial on early detection of this disease and would allow its use as a precise non-invasive biomarker.
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- Dec 2021
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www.researchsquare.com www.researchsquare.com
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Chertow, Daniel, Sydney Stein, Sabrina Ramelli, Alison Grazioli, Joon-Yong Chung, Manmeet Singh, Claude Kwe Yinda, et al. ‘SARS-CoV-2 Infection and Persistence throughout the Human Body and Brain’, 28 December 2021. https://doi.org/10.21203/rs.3.rs-1139035/v1.
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- Apr 2021
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www.nature.com www.nature.com
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Korman, Maria, Vadim Tkachev, Cátia Reis, Yoko Komada, Shingo Kitamura, Denis Gubin, Vinod Kumar, and Till Roenneberg. ‘COVID-19-Mandated Social Restrictions Unveil the Impact of Social Time Pressure on Sleep and Body Clock’. Scientific Reports 10, no. 1 (17 December 2020): 22225. https://doi.org/10.1038/s41598-020-79299-7.
Tags
- restrictions
- sleep
- discrepancy
- human
- COVID-19
- body
- time
- young adults
- school
- sleep deficit
- workdays
- pressure
- regulation
- GCCS
- is:article
- SJL
- work-free days
- intervention
- meals
- global
- Global Chrono Corona Survey
- social
- social jetlag
- clock
- work
- epidemiology
- lang:en
- alarm clock
- quantification
Annotators
URL
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- Jan 2019
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static1.squarespace.com static1.squarespace.com
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We regularly, in the interests of Plato-worship, disembody language and reason, with the narrow-mindedness Mark Johnson points out in an important recent book, The Body in the Mindl3 Our persistent evasion of the "Q" question makes for a great deal of self-centered, self-serving preaching and a great deal of self-satisfied practice. We do sometimes follow that master of contemptuous, self-satisfied self-absorp-tion, the Platonic Socrates, closely indeed.
This reminds me of Albert Camus' thoughts on absurdity, and what James Cone says in his book Black Theology and Black Power: "All aspects of this society have participated in the act of enslaving blacks, extinguishing Indians, and annihilating all who question white society's right to decide who is human....Absurdity arises as the black man seeks to understand his place in the white world. The black man does not view himself as absurd; he views himself as human. But as he meets the white world and its values, he is confronted with an almighty No and is defined as a thing. This produces the absurdity."
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- Jun 2018
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www.lancaster.ac.uk www.lancaster.ac.uk
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One consequence of thisposition is a more radical understanding of the sense in whichmateriality is discursive (i.e., material phenomena are inseparable from theapparatuses of bodily production: matteremerges out of and includes as part of itsbeing the ongoing reconfiguring of boundaries), just as discursive practices arealways already material (i.e., they are ongoing material (re)configurings of theworld) (2003: 822).Brought back into the world oftechnology design, this intimate co-constitution ofconfigured materialities with configuring agencies clearly implies a very differentunderstanding of the ‘human-machine interface’.
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