184 Matching Annotations
  1. Last 7 days
  2. Jan 2022
  3. Dec 2021
  4. Nov 2021
    1. Those structures reveal that Ag+ binds to 6PGDH at both catalytic and non-catalytic sites with dominant binding residues of Cys, His and Met in quasi-linear and trigonal geometry, which is generally consistent with our previous reports36,40. Together with the site-directed mutagenesis study, we unveil that Ag+ abolishes the enzymatic activity of 6PGDH through targeting His185 in the active site and morphing its catalytic pocket.

      Ag can bind with protein at Cys, His and Met residues.

  5. Oct 2021
  6. Sep 2021
    1. A mental model is what the user believes about the system at hand.

      “Mental models are one of the most important concepts in human–computer interaction (HCI).”

      — Nielsen Norman Group

    1. Researchers of online courses in community colleges found that the level of interpersonal interaction was the best predictor of how well an online course did.

      Research shows that the level of interpersonal interaction is the best predictor for how well an online course does.

      Reference for this??

  7. Jul 2021
  8. Jun 2021
    1. ?seq

      ?function doesn't work for mean in the interactive R console (i am using firefox browser) - the running of the scripts and other rconsole interactions does work

    1. Anita: So, what happened to you in the States? So that you ended up back here?Ivan: I was in the wrong car. So, I was in a car that, they pulled us over and I was just with the people, but they'd said that—well they found drugs in the car. So, they blamed me. But I was on the passenger side. So, I know that the rules is whoever's driving or the car owner has to be responsible. But they did not take it like that. They just said... I didn't want to give them my name because I was scared. So, they took me for that too, giving a false name. But on top of that they put all the charges on me. So, they charged me for all the drugs because they didn't want to take the charge.Anita: So, they charged you instead of the person who had the drugs?Ivan: Yes. Yes, that's true.Anita: Why'd they do that?Ivan: I don't know, but they did. They didn't want to take the charge. But I mean, I was just with them because I was going to Walmart to do a return and they stopped us in a traffic stop and they blamed it all on me. I was trying to fight my case, but it was taking too long. I was getting too stressed out being inside in jail so I just signed the papers. I just wanted to get out, so I just took the charge.

      explanation of how he ended up back in Mexico.

  9. May 2021
  10. Apr 2021
    1. Can we reconfigure growth to mean richness in difference? Flourishing interdependent diversity of networks, network protocols and forms of interaction? What does this mean for digital decay, and can the decay of files, applications and networks become some form of compost, or what might be the most dignified form of digital death and rebirth?

      Also see Apoptosis

  11. Mar 2021
  12. Feb 2021
  13. parsejournal.com parsejournal.com
    1. ntra-action with the world rather than in the head of the autonomous subject, and as a sensuous and sensory practice in which mind and body are indistinguishable.
  14. Jan 2021
  15. Dec 2020
    1. The following ANOVA table illustrates the relationship between the sums of squares for each component and the resulting F-statistic for testing the three null and alternative hypotheses for a two-way ANOVA.

      The following ANOVA table illustrates the relationship between the sums of squares for each component and the resulting F-statistic for testing the three null and alternative hypotheses for a two-way ANOVA.

  16. Nov 2020
  17. Oct 2020
    1. This piece makes a fascinating point about people and interactions. It's the sort of thing that many in the design and IndieWeb communities should read and think about as they work.

      I came to it via an episode of the podcast The Happiness Lab.

    2. “Social” media: This is social interaction that isn’t really social. While Facebook and others frequently claim to offer connection, and do offer the appearance of it, the fact is a lot of social media is a simulation of real connection.

      Perhaps this is one of the things I like most about the older blogosphere and it's more recent renaissance with the IndieWeb idea of Webmentions, a W3C recommendation spec for online interactions? While many of the interactions I get are small nods in the vein of likes, favorites, or reposts, some of them are longer, more visceral interactions.

      My favorite just this past week was a piece that I'd worked on for a few days that elicited a short burst of excitement from someone who just a few minutes later wrote a reply that was almost as long as my piece itself.

      To me this was completely worth the effort and the work, not because of the many other smaller interactions, but because of the human interaction that resulted. Not to mention that I'm still thinking out a reply still several days later.

      This sort of human social interaction also seems to be at the heart of what Manton Reece is doing with micro.blog. By leaving out things like reposts and traditional "likes", he's really creating a human connection network to fix what traditional corporate social media silos have done to us. This past week's episode of Micro Monday underlines this for us.

    3. Most of the tech news we get barraged with is about algorithms, AI, robots, and self-driving cars, all of which fit this pattern. I am not saying that such developments are not efficient and convenient; this is not a judgment. I am simply noticing a pattern and wondering if, in recognizing that pattern, we might realize that it is only one trajectory of many. There are other possible roads we could be going down, and the one we’re on is not inevitable or the only one; it has been (possibly unconsciously) chosen.
    4. And in the meantime, if less human interaction enables us to forget how to cooperate, then we lose our advantage.

      It may seem odd, but I think a lot of the success of the IndieWeb movement and community is exactly this: a group of people has come together to work and interact and increase our abilities to cooperate to make something much bigger, more diverse, and more interesting than any of us could have done separately.

  18. Sep 2020
    1. Sometimes we can escape them, by speeding away in a power chair

      This reminds me of Zoom calls and how easy it can be to escape a social interaction through muting and turning off your camera. It almost becomes normal to sit in silence, and I am just as guilty as everyone else, sometimes you just don't want to talk to anyone that day. However, this is still sad to think about.

  19. Aug 2020
    1. Hogan, A. B., Jewell, B. L., Sherrard-Smith, E., Vesga, J. F., Watson, O. J., Whittaker, C., Hamlet, A., Smith, J. A., Winskill, P., Verity, R., Baguelin, M., Lees, J. A., Whittles, L. K., Ainslie, K. E. C., Bhatt, S., Boonyasiri, A., Brazeau, N. F., Cattarino, L., Cooper, L. V., … Hallett, T. B. (2020). Potential impact of the COVID-19 pandemic on HIV, tuberculosis, and malaria in low-income and middle-income countries: A modelling study. The Lancet Global Health, 0(0). https://doi.org/10.1016/S2214-109X(20)30288-6

  20. Jul 2020
  21. Jun 2020
    1. De plus, il n’est pas toujours nécessaire d’être dans le virtuel pour communiquer et aider les enfants autistes. Une collaboration entre deux chercheures du Québec et de la France ont mené à la création du site Litter-action'ailes. Ce site explique en détail comment utiliser la littérature jeunesse pour développer l’interaction auprès des autistes et favoriser leur communication et leur compréhension. La première partie explicite les théories sur lesquelles se sont basées les deux femmes pour développer les approches avec les livres. Le second segment se concentre sur des façons concrètes des différentes difficultés liées aux autistes et comment des activités de littérature peuvent être mises en place pour régler ces problèmes. En plus de description, le site offre des diaporamas et des vidéos montrant bien comment se déroulent les activités.

      Argument qui rejoint le précédant, le virtuel n'est pas le seul élément pour répondre aux besoins spécifiques des enfants autistes. D'autres types de médiations existent et sont accessibles sur internet pour les personnes qui souhaitent développer de nouvelles méthodes d'apprentissage.

  22. May 2020