324 Matching Annotations
  1. Last 7 days
  2. Jul 2021
    1. Now that they are part of comedy history, it can be hard to imagine George Carlin’s most famous routines as anything but finished products. Whether the infamous “Seven Words” from his album Class Clown (released exactly 45 years ago Friday) or the monologues from his hosting of the first-ever episode of Saturday Night Live (which returns for its 43rd season this Saturday), these routines can seem to have sprung fully formed from his mind. But there’s plenty of physical evidence to the contrary.

      It's rarely ever the case (my cognitive bias statement), that anything springs fully formed from the mind.

      Generally there's an infrastructure, a system, a method by which ideas or physical things are aggregated, accumulated, and edited into existence.

      When seeing them well done, they appear magical because we don't see the work or the process. We will often call them genius, when in reality, they're the result of long hard work.

      Take the Pyramids of Giza. They look large and magesterial---and likely moreso in their non-degraded form. But is it so mystical how they may have been built if we were to see the structure and scaffolding that likely went into constructing them?

  3. Jun 2021
    1. Note that every call of sample(1:6, 3, replace = T) gives a different outcome since we draw with replacement at random. To allow you to reproduce the results of computations that involve random numbers, we will used set.seed() to set R’s random number generator to a specific state. You should check

      In general I really like the online approach etc! really appreciated. I am now actively using and studying through this book. I think what would be super useful is to show some kind of equivalent of page numbers. Going back and forth between sections and scrolling up and down really makes me lose track of where i was.

  4. May 2021
    1. The most common way to stage an argument in the thesis goes something like this: Here is a puzzle/problem/question worth asking. If we know more about this puzzle/problem/question then something significant (policy, practice, more research) can happen.Here is what we already know about the puzzle/problem/question. I’ve used this existing knowledge (literatures) to help: my thinking and approach; my research design; make sense of my results; and establish where my scholarly contribution will be. Here is how I designed and did the research in order to come up with an “answer”.Here’s the one/two/three clusters of results.Missing stepNow here’s my (summarised) “answer” to the puzzle/problem/question I posed at the start. On the back of this answer, here’s what I claim as my contribution(s) to the field. Yes I didn’t do everything, but I did do something important. Because we now know my answer, and we didn’t before I did the research, then here are some possible actions that might arise in policy/practice/research/scholarship.
    1. It is never just the developers or coding that makes an app successful. The fact is – there are piles of factors contributing to the success of a mobile app; Like the business idea, look and feel of the app, user journeys, efficient algorithms, architecture solutions, adequate risk management, security, and so on.
  5. Mar 2021
    1. In computer science, a tree is a widely used abstract data type that simulates a hierarchical tree structure

      a tree (data structure) is the computer science analogue/dual to tree structure in mathematics

  6. Feb 2021
    1. The adapter is where authentication, policy checks, and eventually your domain logic happen. All termini of the protocol’s activity are standardized end events - that’s how protocol and adapter communicate.
    1. Trailblazer offers you a new, more intuitive file layout in applications.
    2. Instead of grouping by technology, classes and views are structured by concept, and then by technology. A concept can relate to a model, or can be a completely abstract concern such as invoicing.
    3. Concepts over Technology
    4. While Trailblazer offers you abstraction layers for all aspects of Ruby On Rails, it does not missionize you. Wherever you want, you may fall back to the "Rails Way" with fat models, monolithic controllers, global helpers, etc. This is not a bad thing, but allows you to step-wise introduce Trailblazer's encapsulation in your app without having to rewrite it.
    1. c0 0000 00

      The "size", defined by the expression `varsize + strx + comsize + (pc + nofimps + nofent + nofptrs + 1)4; (varsize includes type descriptors*), where these names match those used by the code generator ORG.Mod. Used by the module loader for determining how big of a hole needs to be used to accommodate the module in main memory when imported by another module or invoked to service a user command.

    2. 01

      The version/class of the object file format used here. Special class 0 is used for the bootloader.

    3. b765 6d6c

      The module "key"—a signature computed by the Oberon compiler, used for verification by the linker.

      Note that this is stored as a little-endian 32-bit word. This is the native byte order. (Signed integers use two's complement arithmetic.)

    4. 4865 6c6c 6f00

      NUL-terminated module name, as ASCII.

  7. Jan 2021
  8. Dec 2020
    1. Types of Structure Outliners take advantage of what may be the most primitive of relationships, probably the first one you learned as an infant: in. Things can be in or contained by other things; alternatively, things can be superior to other things in a pecking order. Whatever the cognitive mechanics, trees/hierarchies are a preferred way of structuring things. But it is not the only way. Computer users also encounter: links, relationships, attributes, spatial/tabular arrangements, and metaphoric content. Links are what we know from the Web, but they can be so much more. The simplest ones are a sort of ad hoc spaghetti connecting pieces of text to text containers (like Web pages), but we will see many interesting kinds that have names, programs attached, and even work two-way. Relationships are what databases do, most easily imagined as “is-a” statements which are simple types of rules: Ted is a supervisor, supervisors are employees, all employees have employee numbers. Attributes are adjectives or tags that help characterize or locate things. Finder labels and playlists are good examples of these. Spatial/tabular arrangements are obvious: the very existence of the personal computer sprang from the power of the spreadsheet. Metaphors are a complex and powerful technique of inheriting structure from something familiar. The Mac desktop is a good example. Photoshop is another, where all the common tools had a darkroom tool or technique as their predecessor.

      Structuring Information

      Ted Goranson holds that there are only a couple of ways to structure information.

      In — Possibly the most primitive of relationships. Things can be in other things and things can be superior to other things.

      Links —Links are what we know from the web, but these types of links or only one implementation. There are others, like bi-directional linking.

      Relationships — This is what we typically use databases for and is most easily conceived as "is-a" statements.

      Attributes — Adjectives or tags that help characterize or locate things.

      Metaphors — A technique for inheriting structure from something familiar.

  9. Nov 2020
    1. example of poor target accessibility, manifested by the significant number of mid-level amplitude droplets (that is, rain), which is resolved by performing a restriction digestion on the DNA before ddPCR
  10. Oct 2020
    1. The results of a DEXA scan are most often reported as T-scores. A T-score compares a person’s bone density to the average peak bone density of a healthy 30-year-old population of the same gender. A T-score of −1.0 or above indicates normal bone density. A person with a T-score between −1.0 and −2.5 has low bone density, which is a condition referred to as osteopenia. A person with a T-score of −2.5 or below is diagnosed with osteoporosis.

      T score levels for bone density.

    1. La distinction entre les mondes marchand et non marchand sépare moins deux populations différentes qu’elle ne traverse chaque internaute publiant en quête de réputation et de visibilité. Beaucoup d’entre eux ne cessent de calculer, cherchent à se faire voir et sont en compétition pour obtenir une place de choix dans les résultats « organiques » du moteur de recherche. Et pour cela, ils vont entreprendre de déformer à leur profit la structure des liens de la Toile, afin de capturer un surcroît de l’autorité dispensée par le PageRank.

      Non seulement ça, mais l'Internet encourage de plus en plus la culture du hustling, qui encourage chacun (en particulier les millénaux qui peinent à joindre les deux bouts) à tenter de capitaliser sur le moindre de ses talents.

    2. Car la condition essentielle de son fonctionnement est que les internautes n’aient pas agi en fonction du PageRank, mais que leur choix de liens distribue de façon « naturelle » les honneurs et les oublis. Si les jugements qu’ils s’échangent à travers les liens ont été produits en fonction du méta-coordinateur qui les agrège, la pertinence épistémique du résultat en sera profondément altérée.

      Un peu de la même manière que l'observateur d'une population influence toujours les observations anthropologique, ou que les études cliniques peuvent être biaisées si les participants connaissent à l'avance l'hypothèse exacte que les chercheurs veulent vérifier.

    3. PageRank est un champion de la démocratie […] : tout lien pointant de la page A à la page B est considéré comme un vote de la page A en faveur de la page B.

      D'où la pertinence de sites comme donotlink.com (aujourd'hui désuet) et la propriété rel="nofollow" sur les hyperliens. Article de blog intéressant à ce sujet: https://skeptools.wordpress.com/2015/02/16/nofollow-donotlink-best-practice-skeptic/

    1. In the third step of bone remodeling, the site is prepared for building. In this stage, sugars and proteins accumulate along the bone’s surface, forming a cement line which acts to form a strong bond between the old bone and the new bone that will be made. These first three steps take approximately two to three weeks to complete.

      Bone remodeling process.

    2. In adulthood, our bones stop growing and modeling, but continue to go through a process of bone remodeling.

      I would challenge that fact.

    3. Bone tissue cells include osteoprogenitor cells, osteoblasts, osteoclasts, and osteocytes. The osteoprogenitor cells are cells that have not matured yet. Once they are stimulated, some will become osteoblasts, the bone builders, and others will become osteoclasts, the cells that break bone down. Osteocytes are the most abundant cells in bone tissue. Osteocytes are star-shaped cells that are connected throughout the bone and exchange nutrients from bones to the blood and lymph.

      The Asteo Class of Bone Tissue

    4. Your bones are stronger than reinforced concrete. Bone tissue is a composite of fibrous collagen strands that resemble the steel rebar in concrete and a hardened mineralized matrix that contains large amounts of calcium, just like concrete.

      What Is Bone?

    1. Doctoral programs are often highly unstructured learning and training environments, where individual autonomy and freedom are highly valued. Decisions as to what counts as a good idea, a worthwhile project, or adequate progress are often left to the discretion of professors, and criteria for success can be opaque for students. This is even more so for those who are not already “in the know.”
    1. in E

      An example to reinforce the statement made in the previous paragraph

    2. 2-3). This article proposes to take up where Frank furt left off and to address the question of bullshit in a way that is especially pertinent to academics, even more pertinent to people in the humanities and social sciences, and most pertinent of all to those who specialize in rhetoric and writin

      Thesis?

    3. Philip Eubanks and John D. Schaeffe

      Authors

    1. I call it the detective-fever; and I first caught it in the company of Sergeant Cuff

      For some reason this little section is so funny to me. It almost reads like a Buddy Comedy or something. I also think that it's sort of supposed to feel like a bit like things are starting to come full circle as we get near to the end of the story. The same setting is back, the same jokes are back, we're back with Betteredge and encouraged to feel comforted by that through Franklin's narrative.

  11. Sep 2020
  12. Aug 2020
    1. Walls, A. C., Fiala, B., Schäfer, A., Wrenn, S., Pham, M. N., Murphy, M., Tse, L. V., Shehata, L., O’Connor, M. A., Chen, C., Navarro, M. J., Miranda, M. C., Pettie, D., Ravichandran, R., Kraft, J. C., Ogohara, C., Palser, A., Chalk, S., Lee, E.-C., … King, N. P. (2020). Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2. BioRxiv, 2020.08.11.247395. https://doi.org/10.1101/2020.08.11.247395

    1. Kreye, J., Reincke, S. M., Kornau, H.-C., Sánchez-Sendin, E., Corman, V. M., Liu, H., Yuan, M., Wu, N. C., Zhu, X., Lee, C.-C. D., Trimpert, J., Höltje, M., Dietert, K., Stöffler, L., Wardenburg, N. von, Hoof, S. van, Homeyer, M. A., Hoffmann, J., Abdelgawad, A., … Prüss, H. (2020). A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model. BioRxiv, 2020.08.15.252320. https://doi.org/10.1101/2020.08.15.252320

    1. Hsieh, C.-L., Goldsmith, J. A., Schaub, J. M., DiVenere, A. M., Kuo, H.-C., Javanmardi, K., Le, K. C., Wrapp, D., Lee, A. G., Liu, Y., Chou, C.-W., Byrne, P. O., Hjorth, C. K., Johnson, N. V., Ludes-Meyers, J., Nguyen, A. W., Park, J., Wang, N., Amengor, D., … McLellan, J. S. (2020). Structure-based design of prefusion-stabilized SARS-CoV-2 spikes. Science. https://doi.org/10.1126/science.abd0826

    1. Equivalent to role="region". Content that needs extra context from its parent sectioning element to make sense. This is a generic sectioning element that is used whenever it doesn’t make sense to use the other more semantic ones.
    2. Content that is self-contained in that it makes sense on its own when taken out of context. That could mean a widget, a blog post or even a comment within a blog post.
  13. Jul 2020
  14. Jun 2020
    1. Oh, and to be absolutely clear, every example that I know of a company trying to adopt the "pioneer - settler - town planner" structure without first getting their principles in a decent state has ... failed. Principles first. Org structure later. Culture, later still.

      Thinking on this with respect to Colin Woodard's book American Nations, makes me realize why America is in such horrible shape today.

    1. normalizing our dabatase will help us. What means normalize? Well, it simply means to separate our information as much as we can

      directly contradicts firebase's official advice: denormalize the structure by duplicating some of the data: https://youtu.be/lW7DWV2jST0?t=378

  15. May 2020
    1. We believe everyone deserves to report to exactly one person that knows and understands what you do day to day. The benefit of having a technically competent manager is easily the largest positive influence on a typical worker’s level of job satisfaction. We have a simple functional hierarchy, everyone has one manager that is experienced in their subject matter.
    2. We don't want a matrix organization where you work with a lead day to day but formally report to someone else.
  16. Apr 2020