285 Matching Annotations
  1. Sep 2023
  2. www.biorxiv.org www.biorxiv.org
    Caspase-4 dimerisation and D289 auto-processing elicits an interleukin-1β converting enzyme
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    1. EMBOpress 06 Sep 2023

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    biorxiv.org/content/10.1101/2023.01.05.522955v1
  3. www.biorxiv.org www.biorxiv.org
    Neuroprotective effects of hepatoma-derived growth factor in models of Huntington's disease
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    1. EMBOpress 06 Sep 2023

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    biorxiv.org/content/10.1101/2023.02.23.529222v1
  4. www.biorxiv.org www.biorxiv.org
    Structural evidence for elastic tethers connecting separating chromosomes in crane-fly spermatocytes
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    1. EMBOpress 06 Sep 2023

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    biorxiv.org/content/10.1101/2023.05.28.541924v1
  5. www.biorxiv.org www.biorxiv.org
    A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance
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    1. EMBOpress 06 Sep 2023

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    biorxiv.org/content/10.1101/2023.02.26.530079v2
  6. www.biorxiv.org www.biorxiv.org
    Estimation of crossbridge-state during cardiomyocyte beating using second harmonic generation
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    1. EMBOpress 01 Sep 2023

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    biorxiv.org/content/10.1101/2022.10.13.512034v1
  7. www.biorxiv.org www.biorxiv.org
    Identification of a novel enhancer essential for Satb1 expression in TH2 cells and activated ILC2s.
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    1. EMBOpress 01 Sep 2023

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    biorxiv.org/content/10.1101/2023.01.03.522551v1
  8. www.biorxiv.org www.biorxiv.org
    Spatial metabolomics for symbiotic marine invertebrates
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    1. EMBOpress 01 Sep 2023

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    biorxiv.org/content/10.1101/2022.10.05.511040v1
  9. www.biorxiv.org www.biorxiv.org
    MAP4K3 inhibits Sirtuin-1 to repress LKB1-AMPK to promote amino acid dependent activation of mTORC1
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    1. EMBOpress 01 Sep 2023

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    biorxiv.org/content/10.1101/2021.11.08.467702v2
  10. www.biorxiv.org www.biorxiv.org
    Origin and segregation of the human germline
    1
    1. EMBOpress 01 Sep 2023

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    biorxiv.org/content/10.1101/2022.07.06.498671v1
  11. www.biorxiv.org www.biorxiv.org
    Apolipoprotein E intersects with amyloid-β within neurons
    1
    1. EMBOpress 01 Sep 2023

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    biorxiv.org/content/10.1101/2022.12.13.520238v1
  12. www.biorxiv.org www.biorxiv.org
    Distant sequence regions of JBP1 contribute to J-DNA binding
    1
    1. EMBOpress 01 Sep 2023

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    biorxiv.org/content/10.1101/2023.01.23.525147v1
  13. www.biorxiv.org www.biorxiv.org
    IKBKB reduces huntingtin aggregation by phosphorylating Serine 13 via a non-canonical IKK pathway
    1
    1. EMBOpress 01 Sep 2023

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    biorxiv.org/content/10.1101/2022.12.05.519070v1
  14. www.biorxiv.org www.biorxiv.org
    Germinal Centers Convergent Evolution and B cell Recirculation in Human Lymph Nodes
    1
    1. EMBOpress 01 Sep 2023

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    biorxiv.org/content/10.1101/2022.11.09.463832v9
  15. Aug 2023
  16. www.biorxiv.org www.biorxiv.org
    NLRP3 controls ATM activation in response to DNA damage.
    1
    1. EMBOpress 26 Aug 2023

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    biorxiv.org/content/10.1101/2020.05.12.087015v1
  17. www.biorxiv.org www.biorxiv.org
    The C-terminal tail of CSNAP attenuates the CSN complex
    1
    1. EMBOpress 03 Aug 2023

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    biorxiv.org/content/10.1101/2022.07.18.500399v1
  18. Jul 2023
  19. www.biorxiv.org www.biorxiv.org
    Comparative membrane proteomics reveals diverse cell regulators concentrated at the nuclear envelope
    1
    1. EMBOpress 29 Jul 2023

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    biorxiv.org/content/10.1101/2023.02.13.528342v1
  20. www.biorxiv.org www.biorxiv.org
    Characterizing control of memory CD8 T cell differentiation by BTB-ZF transcription factor Zbtb20
    1
    1. EMBOpress 29 Jul 2023

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    biorxiv.org/content/10.1101/2022.08.22.504726v1
  21. www.biorxiv.org www.biorxiv.org
    Extracellular matrix sensing via modulation of orientational order of integrins and F-actin in focal adhesions
    1
    1. EMBOpress 27 Jul 2023

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    biorxiv.org/content/10.1101/2022.07.22.501116v2
  22. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2021.11.16.468777
    1
    1. EMBOpress 27 Jul 2023

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    biorxiv.org/content/10.1101/2021.11.16.468777v1
  23. www.biorxiv.org www.biorxiv.org
    Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation
    1
    1. EMBOpress 13 Jul 2023

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    biorxiv.org/content/10.1101/2023.03.29.534741v1
  24. www.biorxiv.org www.biorxiv.org
    The cytochrome b carboxyl-terminal region is necessary for mitochondrial Complex III assembly
    1
    1. EMBOpress 13 Jul 2023

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    biorxiv.org/content/10.1101/2022.11.25.517933v1
  25. www.biorxiv.org www.biorxiv.org
    arfA antisense RNA regulates MscL excretory activity
    1
    1. EMBOpress 13 Jul 2023

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    biorxiv.org/content/10.1101/2022.11.21.517365v1
  26. www.biorxiv.org www.biorxiv.org
    Antibody reliability influences observed mRNA-protein correlations in tumour samples
    1
    1. EMBOpress 13 Jul 2023

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    biorxiv.org/content/10.1101/2022.12.23.521733v1
  27. www.biorxiv.org www.biorxiv.org
    N-terminal proteoforms may engage in different protein complexes
    1
    1. EMBOpress 13 Jul 2023

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    biorxiv.org/content/10.1101/2023.01.17.524352v2
  28. www.biorxiv.org www.biorxiv.org
    PI3P dependent regulation of cell size and autophagy by phosphatidylinositol 5-phosphate 4-kinase
    1
    1. EMBOpress 13 Jul 2023

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    biorxiv.org/content/10.1101/2022.06.18.496676v2
  29. www.biorxiv.org www.biorxiv.org
    Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes.
    1
    1. EMBOpress 13 Jul 2023

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    biorxiv.org/content/10.1101/2022.10.14.512296v1
  30. Jun 2023
  31. www.biorxiv.org www.biorxiv.org
    Accurate genotype-based demultiplexing of single cell RNA sequencing samples from non-human animals
    1
    1. EMBOpress 29 Jun 2023

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    biorxiv.org/content/10.1101/2022.09.22.508993v1
  32. www.biorxiv.org www.biorxiv.org
    Structure-based design and characterization of Parkin activating mutations
    1
    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.02.22.481412v1
  33. www.biorxiv.org www.biorxiv.org
    Mitochondrial dysfunction rapidly modulates the abundance and thermal stability of cellular proteins
    1
    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.10.27.514032v1
  34. www.biorxiv.org www.biorxiv.org
    Upf3a is dispensable for nonsense-mediated mRNA decay in mouse pluripotent and somatic cells
    1
    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.07.04.495064v2
  35. www.biorxiv.org www.biorxiv.org
    Structural insights into ubiquitin chain cleavage by Legionella ovarian tumor deubiquitinases
    1
    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2023.01.02.522462v1
  36. www.biorxiv.org www.biorxiv.org
    The pro-inflammatory response to influenza A virus infection is fueled by endothelial cells
    1
    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.08.19.504520v1
  37. www.biorxiv.org www.biorxiv.org
    Missense variant interaction scanning reveals a critical role of the FERM-F3 domain for tumor suppressor protein NF2 conformation and function
    1
    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.12.11.519953v2
  38. May 2023
  39. www.biorxiv.org www.biorxiv.org
    BAZ2A-RNA mediated association with TOP2A and KDM1A represses gene expression in prostate cancer
    1
    1. EMBOpress 31 May 2023

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    biorxiv.org/content/10.1101/2021.07.15.452487v2
  40. www.biorxiv.org www.biorxiv.org
    Recursive splicing discovery using lariats in total RNA sequencing
    1
    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.12.22.521701v1
  41. www.biorxiv.org www.biorxiv.org
    Exploratory Meta-Analysis of Hypoxic Transcriptomes Using a Precise Transcript Reference Sequence Set
    1
    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.05.01.489280v2
  42. www.biorxiv.org www.biorxiv.org
    VEGFR3 modulates brain microvessel branching in a mouse model of 22q11.2 deletion syndrome
    1
    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.03.16.484566v1
  43. www.biorxiv.org www.biorxiv.org
    Telescoping bimodal latent Dirichlet allocation to identify expression QTLs across tissues
    1
    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2021.10.27.466156v2
  44. www.biorxiv.org www.biorxiv.org
    RAS and PP2A activities converge on epigenetic gene regulation
    1
    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.05.11.491459v1
  45. www.biorxiv.org www.biorxiv.org
    Functional substitutions of amino acids that differ between GDF11 and GDF8 impact skeletal development and skeletal muscle.
    1
    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.05.09.491247v1
  46. www.biorxiv.org www.biorxiv.org
    Gapless provides combined scaffolding, gap filling and assembly correction with long reads
    1
    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.03.08.483466v2
  47. www.biorxiv.org www.biorxiv.org
    Z-Flipon Variants reveal the many roles of Z-DNA and Z-RNA in health and disease
    1
    1. EMBOpress 24 May 2023

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    biorxiv.org/lookup/doi/10.1101/2023.01.12.523822
  48. www.biorxiv.org www.biorxiv.org
    The value of genotype-specific reference for transcriptome analyses
    1
    1. EMBOpress 14 May 2023

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    biorxiv.org/content/10.1101/2021.09.14.460213v1
  49. www.biorxiv.org www.biorxiv.org
    Genome-wide CRISPRi screening reveals regulators of Alzheimee's tau pathology shared between exosomal and vesicle-free tau seeds.
    1
    1. EMBOpress 14 May 2023

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    biorxiv.org/content/10.1101/2022.04.26.489622v1
  50. www.biorxiv.org www.biorxiv.org
    Small non-coding vault RNA1-2 modulate expression of cell membrane proteins through nascent RNA silencing
    1
    1. EMBOpress 11 May 2023

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    biorxiv.org/content/10.1101/2022.08.12.503724v2
  51. www.biorxiv.org www.biorxiv.org
    LuminoCell: a versatile and affordable luminometer platform for monitoring in-cell luciferase-based reporters
    1
    1. EMBOpress 11 May 2023

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    biorxiv.org/content/10.1101/2022.01.28.478134v1
  52. Apr 2023
  53. www.biorxiv.org www.biorxiv.org
    Efficient knock-in method enabling lineage tracing in zebrafish
    1
    1. EMBOpress 12 Apr 2023

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    biorxiv.org/content/10.1101/2022.07.15.500272v1
  54. www.biorxiv.org www.biorxiv.org
    The TUDOR domain of SMN is an H3K79me1 histone mark reader
    1
    1. EMBOpress 11 Apr 2023

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    biorxiv.org/content/10.1101/2022.10.06.511070v1
  55. www.biorxiv.org www.biorxiv.org
    Preference of CAMSAP3 for microtubules with expanded lattice contributes to stabilization of the minus end
    1
    1. EMBOpress 11 Apr 2023

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    biorxiv.org/content/10.1101/2022.08.21.504720v2
  56. www.biorxiv.org www.biorxiv.org
    Analysis of context-specific KRAS-effectors (sub)complexes in Caco-2 cells
    1
    1. EMBOpress 11 Apr 2023

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  57. Mar 2023
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    Peroxisomes contribute to intracellular calcium dynamics
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    An extended DNA-free intranuclear compartment organizes centrosomal microtubules in Plasmodium falciparum
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    Non-canonical miRNA-RNA base-pairing impedes tumor suppressor activity of miR-16
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    The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation, epithelial repair, and tumor growth
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    Stepwise progression of beta-selection during T cell development as revealed by histone deacetylation inhibition
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    Lack of peroxisomal catalase affects heat shock response in C. elegans
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    Lineage Tracing Reveals Fate Bias and Transcriptional Memory in Human B cells
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    Critical roles of ICOS in controlling Foxp3-expressing T follicular cell subsets during early-stage germinal center reactions
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    The human MRS2 magnesium binding domain is a regulatory feedback switch for channel activity.
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    Activation and inhibition of the C-terminal kinase domain of p90 ribosomal S6 kinases
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    Segregation of pathways leading to pexophagy
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    New algorithms for accurate and efficient de-novo genome assembly from long DNA sequencing reads
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  70. Feb 2023
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    Adenylyl cyclase 9 is auto-stimulated by its isoform-specific carboxyl terminal domain and equipped with paradigm-switching mechanisms.
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    Lung macrophages utilize cathepsin K-dependent phagosomal machinery to degrade intracellular collagen
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    SorCS1 inhibits amyloid-β binding to neurexin and rescues amyloid-β-induced synaptic pathology
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    The GET pathway serves to activate Atg32-mediated mitophagy by ER targeting of the Ppg1-Far complex
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    Human RNA Nm-MTase FTSJ1: new tRNA targets and role in the regulation of brain-specific genes.
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    A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery
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    Epigenetic signals that direct cell type specific interferon beta response in mouse cells
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  78. en.wikipedia.org en.wikipedia.org
    William Whewell - Wikipedia
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      the essay Of the Plurality of Worlds (1853), in which he argued against the probability of life on other planets
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    Convergent evolution and horizontal gene transfer in Arctic Ocean microalgae
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  80. Jan 2023
  81. www.biorxiv.org www.biorxiv.org
    Structural and functional characterization of TraI from pKM101 reveals basis for DNA processing
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    Membrane cholesterol regulates inhibition and substrate transport by the glycine transporter, GlyT2
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    SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis.
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    Epigenetic centromere identity is precisely maintained through DNA replication but is uniquely specified among human cells
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    Identifying novel regulators of placental development using time series transcriptomic data and network analyses
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    De novo discovery of traits co-occurring with chronic obstructive pulmonary disease
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    An isoform-specific function of Cdc42 in regulating mammalian Exo70 during axon formation
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    Comparative analysis of MERFISH spatial transcriptomics with bulk and single-cell RNA sequencing
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    A synergistic activation of RARb and RARg nuclear receptors restores cell-types specialization during stem cells differentiation by hijacking RARa-controlled program
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    Nuclear envelope reshaping around the vacuole determines the morphology of the ribosomal DNA
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    Porcine intestinal innate lymphoid cells and lymphocyte spatial context revealed through single-cell RNA sequencing
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    Sibling rivalry among the ZBTB transcription factor family: homo vs. heterodimers
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  93. Dec 2022
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    Stage-specific gene and transcript dynamics in human male germ cells
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    Cdh5-lineage independent origin of dermal lymphatic vessels revealed by temporally restricted lineage tracing
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    Endoplasmic Reticulum membranes are continuously required to maintain mitotic spindle size and forces
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    Genome-wide Profiling of Histone Modifications in Plasmodium falciparum using CUT&RUN.
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    Systematic analysis of ADP-ribose detection reagents and optimisation of sample preparation to detect ADP-ribosylation in vitro and in cells
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    Drosophila pVALIUM10 TRiP RNAi lines cause undesired silencing of Gateway-based transgenes
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  100. Nov 2022
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    Actin binding domain of Rng2 strongly inhibits actin movement on myosin II HMM through structural changes of actin filaments
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    Miro GTPase domains regulate assembly of the mitochondrial motor-adaptor complex
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    Improving the computation efficiency of polygenic risk score modeling: Faster in Julia
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    Structure of mammalian V-ATPase with the TLDc domain protein mEAK7 bound
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    Profiling subcellular localization of nuclear-encoded mitochondrial gene products in zebrafish
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  106. Oct 2022
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    Replication-associated inversions are the dominant form of bacterial chromosome structural variation
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    Contribution of the Golgi apparatus in morphogenesis of a virus induced cytopathic vacuolar system
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    Regulation of Liprin-α phase separation by CASK is disrupted by a mutation in its CaM kinase domain
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    Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions
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    Synthetic evolution of herbicide resistance using a T7 RNAP-based random DNA base editor
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      PeerReviewed EMBOPress Life Science Alliance synthetic biology
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    biorxiv.org/content/10.1101/2021.11.30.470689v1
  113. www.biorxiv.org www.biorxiv.org
    Evaluation of CA repeat arrays as targets for MeCP2 function in the brain
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    1. EMBOpress 08 Oct 2022

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      PeerReviewed EMBOPress Life Science Alliance genomics
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    biorxiv.org/content/10.1101/2022.04.26.489598v2
  114. Sep 2022
  115. www.biorxiv.org www.biorxiv.org
    Meiotic DNA breaks activate a streamlined phospho-signaling response that largely avoids protein level changes
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    1. EMBOpress 27 Sep 2022

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      PeerReviewed EMBOPress Life Science Alliance cell biology
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    biorxiv.org/content/10.1101/2022.02.24.481857v1
  116. www.biorxiv.org www.biorxiv.org
    Human gene function publications that describe wrongly identified nucleotide sequence reagents are unacceptably frequent within the genetics literature
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    1. EMBOpress 13 Sep 2022

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      PeerReviewed EMBOPress Life Science Alliance genetics
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    biorxiv.org/lookup/doi/10.1101/2021.07.29.453321
  117. Aug 2022
  118. www.biorxiv.org www.biorxiv.org
    Decreasing pdzd8-mediated mitochondrial-ER contacts in neurons improves fitness by increasing mitophagy
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    1. EMBOpress 31 Aug 2022

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    biorxiv.org/content/10.1101/2020.11.14.382861v1
  119. www.biorxiv.org www.biorxiv.org
    Islet Gene View - a tool to facilitate islet research
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    1. EMBOpress 19 Aug 2022

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    biorxiv.org/content/10.1101/435743v3
  120. www.biorxiv.org www.biorxiv.org
    Resolution of the curse of dimensionality in single-cell RNA sequencing data analysis
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    1. EMBOpress 19 Aug 2022

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    biorxiv.org/content/10.1101/2022.05.02.490246v1
  121. www.biorxiv.org www.biorxiv.org
    CFTR modulator response measurements in subjects with cystic fibrosis using 2D differentiated nasal epithelia converted into spheroids
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    1. EMBOpress 18 Aug 2022

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    biorxiv.org/content/10.1101/2021.07.20.453105v2
  122. www.biorxiv.org www.biorxiv.org
    A minimal hepatocyte growth factor mimic acting as a powerful agonist of the MET receptor tyrosine kinase for regeneration of epithelial tissues and organs.
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    1. EMBOpress 17 Aug 2022

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    biorxiv.org/content/10.1101/2020.07.20.212654v3
  123. www.biorxiv.org www.biorxiv.org
    Drosophila insulator proteins exhibit in-vivo liquid-liquid phase separation properties
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    1. EMBOpress 11 Aug 2022

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    biorxiv.org/content/10.1101/2022.05.27.493687v1
  124. www.biorxiv.org www.biorxiv.org
    ScRNA-seq Expression of APOC2 and IFI27 Identifies Four Families of Alveolar Macrophage Superclusters in Cystic Fibrosis and Healthy BALF
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    1. EMBOpress 06 Aug 2022

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      PeerReviewed EMBOPress Life Science Alliance immunology
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    biorxiv.org/content/10.1101/2022.01.30.478325v3
  125. www.biorxiv.org www.biorxiv.org
    ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1
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    1. EMBOpress 02 Aug 2022

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    biorxiv.org/content/10.1101/2021.12.22.473898v2
  126. Jul 2022
  127. www.biorxiv.org www.biorxiv.org
    LncRNA RUS shapes the gene expression program towards neurogenesis
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    1. EMBOpress 13 Jul 2022

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