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  1. Last 7 days
  2. Jan 2023
    1. Selain itu, isolat virus RaTG13 memiliki nilai kekerabatan 96,1%. Virus ini ditemukan di Yunnan, Cina. Sedangkan isolat virus yang berasal dari tenggiling mempunyai nilai kekerabatan sekitar 91%. Adanya nilai kekerabatan yang tinggi ini dimungkinkan akibat dari evolusi yang telah terjadi dari nenek moyang yang sama.

      Untuk diperhatikan, artikel yang dikutip dengan judul "Probable Pangolin Origin of SARS-CoV-2 Associated with the COVID-19 Outbreak" sudah di erratum 3 tahun yang lalu (https://pubmed.ncbi.nlm.nih.gov/32315626/)

      Sehingga masuk dalam jangkauan diskusi PubPeer dengan komentar sebagai berikut:

      Readers should become aware of a preprint (DOI: 10.1101/2020.05.07.077016) entitled "The SARS-CoV-2-like virus found in captive pangolins from Guangdong should be better sequenced" that provides critics to the quality of the sequence runs used in Liu et al. 2019 and also in this paper, to infer the genome sequence of Pangolin-CoV.

      This preprint states, in particular, that "I found the genome assemblies of GD/P virus of poor quality, having high levels of missing data. Additionally, unexpected reads in the Illumina sequencing data were identified. The GD/P2S dataset contains reads that are identical to SARS-CoV-2, suggesting either the coexistence of two SARS-CoV-2-like viruses in the same pangolin or contamination by the human virus".

      Penting bagi penulis untuk menambahkan informasi kebaharuan dan status riset dan temuan terbaru dari artikel yang dikutip. Semoga menjadi koreksi.

      Salam.

    1. I asked why she thought that was happening, and she said, “Covid”. The lack of socialization, especially at such a key time in life, had made this incoming class the first one that lacked basic manners and social skills.

      Covid has heavily impacted our social/communication skills

  3. Dec 2022
    1. forced on the population

      at least in the US, no one is being forced to get a vaccine. Not only that, but there's no evidence anyone's even considered it: https://www.snopes.com/fact-check/forced-vaccines-covid-19/

      Maybe they're talking about another population?

    1. We analyzed URLs cited in Twitter messages before and after the temporary interruption of the vaccine development on September 9, 2020 to investigate the presence of low credibility and malicious information. We show that the halt of the AstraZeneca clinical trials prompted tweets that cast doubt, fear and vaccine opposition. We discovered a strong presence of URLs from low credibility or malicious websites, as classified by independent fact-checking organizations or identified by web hosting infrastructure features. Moreover, we identified what appears to be coordinated operations to artificially promote some of these URLs hosted on malicious websites.
    1. We found that misinformation-exposure scores are significantly positively related to language toxicity (Fig. 3a; b = 0.129, 95% CI = [0.098, 0.159], SE = 0.015, t (4121) = 8.323, p < 0.001; b = 0.319, 95% CI = [0.274, 0.365], SE = 0.023, t (4106) = 13.747, p < 0.001 when controlling for estimated ideology) and expressions of moral outrage (Fig. 3b; b = 0.107, 95% CI = [0.076, 0.137], SE = 0.015, t (4143) = 14.243, p < 0.001; b = 0.329, 95% CI = [0.283,0.374], SE = 0.023, t (4128) = 14.243, p < 0.001 when controlling for estimated ideology). See Supplementary Tables 1, 2 for full regression tables and Supplementary Tables 3–6 for the robustness of our results.
    1. Exposure to elite misinformation is associated with sharing news from lower-quality outlets and with conservative estimated ideology.

      Shown is the relationship between users’ misinformation-exposure scores and (a) the quality of the news outlets they shared content from, as rated by professional fact-checkers21, (b) the quality of the news outlets they shared content from, as rated by layperson crowds21, and (c) estimated political ideology, based on the ideology of the accounts they follow10. Small dots in the background show individual observations; large dots show the average value across bins of size 0.1, with size of dots proportional to the number of observations in each bin.

    1. We find that, during the pandemic, no-vax communities became more central in the country-specificdebates and their cross-border connections strengthened, revealing a global Twitter anti-vaccinationnetwork. U.S. users are central in this network, while Russian users also become net exporters ofmisinformation during vaccination roll-out. Interestingly, we find that Twitter’s content moderationefforts, and in particular the suspension of users following the January 6th U.S. Capitol attack, had aworldwide impact in reducing misinformation spread about vaccines. These findings may help publichealth institutions and social media platforms to mitigate the spread of health-related, low-credibleinformation by revealing vulnerable online communities
    1. we found that social bots played a bridge role in diffusion in the apparent directional topic like “Wuhan Lab”. Previous research also found that social bots play some intermediary roles between elites and everyday users regarding information flow [43]. In addition, verified Twitter accounts continue to be very influential and receive more retweets, whereas social bots retweet more tweets from other users. Studies have found that verified media accounts remain more central to disseminating information during controversial political events [75]. However, occasionally, even the verified accounts—including those of well-known public figures and elected officials—sent misleading tweets. This inspired us to investigate the validity of tweets from verified accounts in subsequent research. It is also essential to rely solely on science and evidence-based conclusions and avoid opinion-based narratives in a time of geopolitical conflict marked by hidden agendas, disinformation, and manipulation [76].
    1. Engagement of religious leaders, for example, has been documented as an important approach to improve vaccine acceptance16,57. Key to the preparation of a COVID-19 vaccine is, therefore, the early and frequent engagement of religious and community-leaders58, and for health authorities to work collaboratively with multiple societal stakeholders to avoid the feeling that they are only acting on behalf of government authorities59.
    2. Similar rates of vaccine hesitance (26% and 25%) and resistance (9% and 6%) were evident in the Irish and UK samples, with only 65% of the Irish population and 69% of the UK population fully willing to accept a COVID-19 vaccine. These findings align with other estimates across seven European nations where 26% of adults indicated hesitance or resistance to a COVID-19 vaccine7 and in the United States where 33% of the population indicated hesitance or resistance34. Rates of resistance to a COVID-19 vaccine also parallel those found for other types of vaccines. For example, in the United States 9% regarded the MMR vaccine as unsafe in a survey of over 1000 adults35, while 7% of respondents across the world said they “strongly disagree” or “somewhat disagree” with the statement ‘Vaccines are safe’36. Thus, upwards of approximately 10% of study populations appear to be opposed to vaccinations in whatever form they take. Importantly, however, the findings from the current study and those from around Europe and the United States may not be consistent with or reflective of vaccine acceptance, hesitancy, or resistance in non-Western countries or regions.
  4. Nov 2022
    1. Our kids have lost so much—family members, connections to friends and teachers, emotional well-being, and for many, financial stability at home. And, of course, they’ve lost some of their academic progress. The pressure to measure—and remediate—this “learning loss” is intense; many advocates for educational equity are rightly focused on getting students back on track. But I am concerned about how this growing narrative of loss will affect our students, emotionally and academically. Research shows a direct connection between a student’s mindset and academic success.
    1. “Our kids have lost so much—family members, connections to friends and teachers, emotional well-being, and for many, financial stability at home,” the article begins, sifting through a now-familiar inventory of devastation, before turning to a problem of a different order. “And of course, they’ve lost some of their academic progress.”
    1. These labor actions underscored the frustrations of teachers, who have had to navigate not only the pandemic but also political harangues about their curricula, as well as insufficient pay and other long-standing issues tied to their actual work as educators. Teachers were already leaving the profession, but stress induced by the pandemic accelerated the pace.
    1. We’re dedicated to providing the highest standards of safety to protect you and your family during your visit to Founders Family Medicine. We screen all patients for COVID-19 symptoms. We also require masks and social distancing at our clinic.

      We’re dedicated to providing the highest standards of safety to protect you and your family during your visit to Founders Family Medicine. We screen all patients for COVID-19 symptoms. We also require masks and social distancing at our clinic.

  5. Oct 2022
    1. Many now find Japanese society’s prevalence for mask wearing and the numerous vestiges of preventative measures (social distancing in some restaurants, compulsory temperature checks and hand sanitizer upon entering facilities with cramped quarters, just to name a few) all an overcautious holdover from another time.

      lol at westerners thinking wearing masks is overly cautious

    1. A study across the population of Scotland researched the affects of covid by comparing those with a positive PCR test with a control group that did not have covid. Vaccinations were shown to decrease symptoms. There are concerns about long-term effects as the virus becomes endemic.

  6. Sep 2022
    1. The North American Division has put together a series of links to offer guidance about vaccines from national and international health organizations, the General Conference, and healthcare experts — with the COVID-19 vaccine highlighted in particular.
  7. Aug 2022
    1. The socioeconomic disruption associated with COVID-19 represents a highly unusual alteration of the human interaction with the Earth System. This alteration is likely to generate a series of responses, illuminating the processes connecting energy, emissions, air quality and climate, as well as globalization, food security, poverty and biodiversity

      La perturbación socioeconómica asociada a COVID-19 representa una alteración muy inusual de la interacción humana con el Sistema Tierra. Es probable que esta alteración genere una serie de respuestas que iluminen los procesos que conectan la energía, las emisiones, la calidad del aire y el clima, así como la globalización, la seguridad alimentaria, la pobreza y la biodiversidad.

    1. Lucas, C., Vogels, C. B. F., Yildirim, I., Rothman, J. E., Lu, P., Monteiro, V., Gelhausen, J. R., Campbell, M., Silva, J., Tabachikova, A., Peña-Hernandez, M. A., Muenker, M. C., Breban, M. I., Fauver, J. R., Mohanty, S., Huang, J., Shaw, A. C., Ko, A. I., Omer, S. B., … Iwasaki, A. (2021). Impact of circulating SARS-CoV-2 variants on mRNA vaccine-induced immunity. Nature, 1–9. https://doi.org/10.1038/s41586-021-04085-y

    1. Gilbert, P. B., Montefiori, D. C., McDermott, A., Fong, Y., Benkeser, D. C., Deng, W., Zhou, H., Houchens, C. R., Martins, K., Jayashankar, L., Castellino, F., Flach, B., Lin, B. C., O’Connell, S., McDanal, C., Eaton, A., Sarzotti-Kelsoe, M., Lu, Y., Yu, C., … Teams, U. S. G. (USG)/CoVPN B. (2021). Immune Correlates Analysis of the mRNA-1273 COVID-19 Vaccine Efficacy Trial. MedRxiv, 2021.08.09.21261290. https://doi.org/10.1101/2021.08.09.21261290

    1. Munro, A. P. S., Janani, L., Cornelius, V., Aley, P. K., Babbage, G., Baxter, D., Bula, M., Cathie, K., Chatterjee, K., Dodd, K., Enever, Y., Gokani, K., Goodman, A. L., Green, C. A., Harndahl, L., Haughney, J., Hicks, A., van der Klaauw, A. A., Kwok, J., … Appleby, K. (2021). Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): A blinded, multicentre, randomised, controlled, phase 2 trial. The Lancet, S0140673621027173. https://doi.org/10.1016/S0140-6736(21)02717-3 s

    1. Chadeau-Hyam, M., Wang, H., Eales, O., Haw, D., Bodinier, B., Whitaker, M., Walters, C. E., Ainslie, K. E. C., Atchison, C., Fronterre, C., Diggle, P. J., Page, A. J., Trotter, A. J., Ashby, D., Barclay, W., Taylor, G., Cooke, G., Ward, H., Darzi, A., … Elliott, P. (2022). SARS-CoV-2 infection and vaccine effectiveness in England (REACT-1): A series of cross-sectional random community surveys. The Lancet Respiratory Medicine, 0(0). https://doi.org/10.1016/S2213-2600(21)00542-7

    1. Kustin, T., Harel, N., Finkel, U., Perchik, S., Harari, S., Tahor, M., Caspi, I., Levy, R., Leschinsky, M., Dror, S. K., Bergerzon, G., Gadban, H., Gadban, F., Eliassian, E., Shimron, O., Saleh, L., Ben-Zvi, H., Amichay, D., Ben-Dor, A., … Stern, A. (2021). Evidence for increased breakthrough rates of SARS-CoV-2 variants of concern in BNT162b2 mRNA vaccinated individuals. MedRxiv, 2021.04.06.21254882. https://doi.org/10.1101/2021.04.06.21254882

    1. Sadoff, J., Gars, M. L., Cardenas, V., Shukarev, G., Vaissiere, N., Heerwegh, D., Truyers, C., Groot, A. M. de, Scheper, G., Hendriks, J., Ruiz-Guinazu, J., Struyf, F., Hoof, J. V., Douoguih, M., & Schuitemaker, H. (2021). Durability of antibody responses elicited by a single dose of Ad26.COV2.S and substantial increase following late boosting (p. 2021.08.25.21262569). https://doi.org/10.1101/2021.08.25.21262569

    1. Pozzetto, B., Legros, V., Djebali, S., Barateau, V., Guibert, N., Villard, M., Peyrot, L., Allatif, O., Fassier, J.-B., Massardier-Pilonchéry, A., Brengel-Pesce, K., Yaugel-Novoa, M., Denolly, S., Boson, B., Bourlet, T., Bal, A., Valette, M., Andrieu, T., Lina, B., … Trouillet-Assant, S. (2021). Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination. Nature, 1–9. https://doi.org/10.1038/s41586-021-04120-y

    1. Thuluva, S., Paradkar, V., Turaga, K., Gunneri, S., Yerroju, V., Mogulla, R., Kyasani, M., Manoharan, S. K., Medigeshi, G., Singh, J., Shaman, H., Singh, C., & Rao, A. V. (2022). Selection of optimum formulation of RBD-based protein sub-unit covid19 vaccine (Corbevax) based on safety and immunogenicity in an open-label, randomized Phase-1 and 2 clinical studies (p. 2022.03.08.22271822). medRxiv. https://doi.org/10.1101/2022.03.08.22271822