28 Matching Annotations
  1. Aug 2022
    1. Munro, A. P. S., Janani, L., Cornelius, V., Aley, P. K., Babbage, G., Baxter, D., Bula, M., Cathie, K., Chatterjee, K., Dodd, K., Enever, Y., Gokani, K., Goodman, A. L., Green, C. A., Harndahl, L., Haughney, J., Hicks, A., van der Klaauw, A. A., Kwok, J., … Appleby, K. (2021). Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): A blinded, multicentre, randomised, controlled, phase 2 trial. The Lancet, S0140673621027173. https://doi.org/10.1016/S0140-6736(21)02717-3 s

    1. Thuluva, S., Paradkar, V., Turaga, K., Gunneri, S., Yerroju, V., Mogulla, R., Kyasani, M., Manoharan, S. K., Medigeshi, G., Singh, J., Shaman, H., Singh, C., & Rao, A. V. (2022). Selection of optimum formulation of RBD-based protein sub-unit covid19 vaccine (Corbevax) based on safety and immunogenicity in an open-label, randomized Phase-1 and 2 clinical studies (p. 2022.03.08.22271822). medRxiv. https://doi.org/10.1101/2022.03.08.22271822

  2. Nov 2021
    1. Each new layer of Life is the result of what scientists call a major evolutionary transition? What was the cause of these transitions the answer is? Cooperation a Major Transition starts when free living creatures team up to form a cooperative group in the early stages of cooperation Participants are free to come and go as they [please] [if] a group sticks together long enough however 00:04:51 Division of labor will often evolve different participants begin specializing in different tasks as time goes on Individuals may become so specialized that they can no longer survive on their own [if] the entire group becomes locked into cooperation Depending fully on one another to survive and reproduce a new super organism has been forged and they made your evolutionary transition is complete 00:05:16 From this point on the entire group will evolve together as one Models describing natural situations that might promote the evolution of major transitions have been put forth by scientists such as John Maynard Smith [fior] Sonck Mary stuart West and w d hamilton using these models Researchers have been able to Mimic natural scenarios in the lab Allowing us to directly witness the beginnings of major transitions [evolved]

      This is the key to Major Evolutionary Transition - a population of free living individual creatures discover that in teaming up, there is a greater resultant evolutionary fitness, mutualism symbiotic relationship emerges. It becomes so strong over time that the many become a self-replicating one.

      The biological self is always defined by a boundary between inner and outer, but in this act of mutualism, the many biological selves join to form a new higher order biological self.

      In this way, a multi-cellular species like ours is somewhat like one of those nested Russian dolls.

      Indeed, Amanda Robins hypothesizes


      that our species has undergone what she and Peter Nonacs calls Major System Transition (MST). The cultural artifact of inscribed language has made possible a superorganism / supraorganism that has spread across the globe.

    2. Today we tend to shrug this off as common knowledge, but think how amazing this is you are a Colony

      This is a great vid for showing how we are a multi-level being. Within this human body, we embed 4 different stages of Major Evolutionary Transitions (MET).

      Our human body is the product of billions of years of evolution, embodying various outputs from each major stage of a Major Evolutionary Transition (MET). We are a multi-cellular being, a colony. Yet,at the same time, we have living elements that at one time in history, were independent living beings which were NOT part of a multi-cellular colony!

      We have genes, that were once autonomous living entities, mitochondria within cells, which at one time were autonomous entities, and cells, which were also once autonomously existent eukaryotes. All three exist in transmuted form that is now integrated into our body.

  3. Sep 2021
  4. Jul 2021
  5. May 2021
  6. Mar 2021
    1. Technological advances have reduced the footprint of communications equipment, making it possible to fit cellular and satellite components into one device, which keeps equipment costs down
  7. Nov 2020
    1. ATP

      ATP better known as Adenosine triphosphate is an energy carrying molecule found in all living things cells. ATP takes the chemical energy from the process of breaking down food molecules to releases it as fuel for cellular processes.

  8. Sep 2020
  9. Aug 2020
    1. Ferretti, A. P., Kula, T., Wang, Y., Nguyen, D. M., Weinheimer, A., Dunlap, G. S., Xu, Q., Nabilsi, N., Perullo, C. R., Cristofaro, A. W., Whitton, H. J., Virbasius, A., Olivier, K. J., Baiamonte, L. B., Alistar, A. T., Whitman, E. D., Bertino, S. A., Chattopadhyay, S., & MacBeath, G. (2020). COVID-19 Patients Form Memory CD8+ T Cells that Recognize a Small Set of Shared Immunodominant Epitopes in SARS-CoV-2. MedRxiv, 2020.07.24.20161653. https://doi.org/10.1101/2020.07.24.20161653

    1. Glasgow, A., Glasgow, J., Limonta, D., Solomon, P., Lui, I., Zhang, Y., Nix, M. A., Rettko, N. J., Lim, S. A., Zha, S., Yamin, R., Kao, K., Rosenberg, O. S., Ravetch, J. V., Wiita, A. P., Leung, K. K., Zhou, X. X., Hobman, T. C., Kortemme, T., & Wells, J. A. (2020). Engineered ACE2 receptor traps potently neutralize SARS-CoV-2. BioRxiv, 2020.07.31.231746. https://doi.org/10.1101/2020.07.31.231746

    1. Clausen, T. M., Sandoval, D. R., Spliid, C. B., Pihl, J., Painter, C. D., Thacker, B. E., Glass, C. A., Narayanan, A., Majowicz, S. A., Zhang, Y., Torres, J. L., Golden, G. J., Porell, R., Garretson, A. F., Laubach, L., Feldman, J., Yin, X., Pu, Y., Hauser, B., … Esko, J. D. (2020). SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. BioRxiv, 2020.07.14.201616. https://doi.org/10.1101/2020.07.14.201616

  10. Jul 2020
    1. Yurkovetskiy, L., Wang, X., Pascal, K. E., Tomkins-Tinch, C., Nyalile, T., Wang, Y., Baum, A., Diehl, W. E., Dauphin, A., Carbone, C., Veinotte, K., Egri, S. B., Schaffner, S. F., Lemieux, J. E., Munro, J., Rafique, A., Barve, A., Sabeti, P. C., Kyratsous, C. A., … Luban, J. (2020). Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant. BioRxiv, 2020.07.04.187757. https://doi.org/10.1101/2020.07.04.187757

  11. Jun 2020
  12. Oct 2019
  13. Jan 2018
    1. The lower the frequency of the band the further it can travel, so the 800MHz band is the most adept of the three at travelling over long distances, which means users can get a 4G signal even when they’re a long way from a mast. This becomes particularly useful in rural areas where masts are likely to be quite spread out.

      Hmm? I assumed 4G was lower range than 3G. From what I read here, 4G can work at a longer range, with lower capacity, scenarios and work at shorter range, high capacity scenarios.

      But only if the cell phone provider has both low frequencies and high frequencies