65 Matching Annotations
  1. Nov 2023
  2. Oct 2023
  3. Dec 2022
    1. So we've got to establish our priorities. And then there's three levels if you will.

      !-- priorities : 3 levels - Short term (next few years) - medium term (next 5 to 10 years) - long term ( next 50 years)

    1. Doing so helps you decide which goals and tasks need to be prioritized now. Try to limit the number of these primary goals and tasks to the most essential. You can always add more later—but the point is to ensure your top priorities have real estate on your calendar.

      Your essential tasks. Limit the number of essential tasks, because if everything’s important, nothing is.

  4. Nov 2022
    1. Un robatiempo es una tarea o reclamo que conlleva el consumo de un tiempo valioso que debería gastarse en temas de mucho más valor añadido o importancia

      This made me think of Warren Buffet’s prioritisation principle

    1. In reality, it’s a framework to consider a “continuum of impact.” If the numbers feel too big, think of the multipliers instead. If your lowest unit value work is $10/hour (i.e. hitting inbox zero), what’s something that’s 10x more impactful? How about 1,000x more impactful?

      I prefer the multipliers over dollar amounts

    2. $10,000 per hour work is the process of identifying your highest leverage activities and committing a small amount of time to them each day.

      The dollar amount one the different types of work is attractive, but may also be a distraction, since most high leverage activities are almost impossible to quantise.

    1. I fail to understand how this is such a low priority. Code review is one of the most basic and critical portions of development lifecycle, and prior to discovery of this ticket I literally had to roll an entire other repository manager just to perform that correctly when I discovered entire directories of changes had been omitted from the Gitlab generated MR. We actually found that in order to get the change set fix to apply reliably, that it is required to add "?w=1" to the url even after updating the white space setting.
  5. Sep 2022
    1. This hasn't yet been scheduled, but we're tracking it on our backlog as something we want to do this year. A few months ago, we arranged for additional capacity to address items like this that have waited for so long. Now that additional capacity is available, it's just a matter of scheduling based on relative priority. We're anxious to get this one done, and I hope to soon have a clearer date to post here.
  6. Aug 2022
  7. May 2022
    1. the skills to tweak an app or website into what they need

      Does "what they need" here implicitly mean "a design that no one really benefits from but you can bill a client for $40+/hr for"? Because that's how Glitch comes off to me—more vocational (and even less academic) than a bootcamp without the structure.

      What was that part about home-cooked meals?

  8. Apr 2022
  9. Oct 2021
  10. May 2021
    1. ReconfigBehSci on Twitter: ‘am I the only one discomfited by the fact that US teenagers are being vaccinated while an out of control pandemic rages in India and Nepal? I would have expected more discussion of this!’ / Twitter. (n.d.). Retrieved 14 May 2021, from https://twitter.com/SciBeh/status/1392852883410849796

  11. Mar 2021
    1. This issue hasn’t been deemed a high enough priority to be fixed yet. It will be addressed one day, I’m sure. There are many issues in GLib which many people on the internet think are important.
  12. Feb 2021
  13. Jan 2021
  14. Dec 2020
    1. The official definition of a “close contact” — 15 minutes, within six feet — isn’t foolproof.

      The takeaway: The official definition of a "close contact" for COVID-19 is not foolproof.

      The claim: The official definition of a "close contact" - 15 minutes, within six feet - isn't foolproof.

      The evidence: In Korea, a person sitting in a restaurant 6.5 meters (>20ft) away from the COVID index case for five minutes was infected, most likely because airflow from the air conditioner carried droplets with COVID-19 from the infected person to the person who became infected (1). How common transmission across large distances occurs is still debated (2). As several indoor outbreaks were attributed to airborne transmission, precautions to prevent airborne COVID transmission are needed (3). Examples include better air filtration/UV to kill virus in the system, increased air flow from outside, avoidance of recirculating interior air, and avoiding overcrowding in interior spaces.

      Sources:

      1) https://jkms.org/DOIx.php?id=10.3346/jkms.2020.35.e415

      2) https://www.sciencedirect.com/science/article/pii/S0166093420302858?via%3Dihub

      3) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454469/pdf/ciaa939.pdf

  15. Nov 2020
    1. Gov. Kristi Noem defended her hands-off approach to managing the deadly COVID-19 pandemic while addressing lawmakers earlier this week and called mandatory stay-at home orders "useless" in helping lower the spread.

      Take away: Lower COVID-19 spread occurred after stay-at home orders were issued. Room for debate exists on how restrictive lockdowns should be.

      The claim: Mandatory stay-at home orders are "useless" in helping lower the spread of SARS-CoV-2.

      The evidence: Two publications showed that lower COVID-19 spread occurred after stay-at home orders were issued (1, 2). Hospitalizations were lower than predicted exponential growth rates after implementation of stay-at home orders (3). Some caveats to consider include that it is impossible to tease apart the effects of the stay-at home orders from other measure implemented simultaneously with stay-at home orders such as increased hygiene measures, social distancing guidelines, and school closures. It is also impossible to conclusively state that the effect is from the stay-at home order and not the natural progression of the disease.

      The comparison between Illinois with stay-at home orders and Iowa without stay-at home orders resulted in an estimated 217 additional COVID-19 cases in Iowa over the course of a month (2). This small number raises the question, "are stay-at home orders worth it?" It is important to remember that comparison of Iowa and Illinois is the comparison of two social distancing strategies. Stay-at home orders close everything and then write the exceptions that can remain open. Iowa took the approach of leaving everything open except what the government choose to close (4). Some businesses in Iowa were still closed and many federal guidelines were still followed. A negative control showing disease progression without any mitigation measures does not exist in published literature.

      Sources:

      1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246016/

      2 https://pubmed.ncbi.nlm.nih.gov/32413112/

      3 https://www.desmoinesregister.com/story/news/2020/04/07/iowa-equivalent-stay-at-home-order-coronavirus-kim-reynolds/2961810001/

      4 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254451/

  16. Oct 2020
    1. 50 percent effective

      Take away: Cloth face masks filter approximately 50% of bacteriophage five times smaller than one SARS-CoV-2 virus. Therefore it is reasonable to assume that masks, including cloth masks, are 50% effective.

      The claim: Masks are assumed to be 50% effective.

      The evidence: Face masks, including home made face masks, were shown to reduce aerosol exposure (1). Masks made from various materials were shown to filter 50-68% of Bacteriophage CS2 which is 20 nm (2). When NaCl aerosols were used instead of a bacteriophage, penetration by NaCl occurred 9-98% of the time depending on the size of the particles (3). Two well written reviews detail the efficacy of facemasks (4, 5). SARS-CoV-2 virus is ~100 nm in size (6).

      Sources: 1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440799/

      2 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108646/

      3 https://academic.oup.com/annweh/article/54/7/789/202744

      4 https://www.preprints.org/manuscript/202004.0203/v1

      5 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497125/#ref23

      6 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224694/#:~:text=SARS%2DCoV%2D2%20is%20an,they%20do%20more%20than%20that.

    1. The model predicted that school closures and isolation of younger people would increase the total number of deaths, albeit postponed to a second and subsequent waves. The findings of this study suggest that prompt interventions were shown to be highly effective at reducing peak demand for intensive care unit (ICU) beds but also prolong the epidemic, in some cases resulting in more deaths long term. This happens because covid-19 related mortality is highly skewed towards older age groups. In the absence of an effective vaccination programme, none of the proposed mitigation strategies in the UK would reduce the predicted total number of deaths below 200 000.

      Take away: This model excludes the possibility of vaccination. As many vaccines are in stage three clinical trials, the conclusion that more people will die from closing schools, etc. will most likely not be realized.

      The claim: School closures and isolation of younger people will increase total number of deaths from second and subsequent waves of COVID-19 when restrictions are lifted.

      The evidence: This model predicts more deaths from the combination of place closures such as schools, case isolations, household quarantine, and social distancing of over 70s than for the combination of case isolation, household quarantine, and social distancing for over 70s. The majority of the deaths for the combination of place closures, case isolations, household quarantine, and social distancing of over 70s occur once the restrictions are lifted. This model excludes the possibility of a vaccine reducing the size of the second wave.

      At least ten companies have a COVID-19 vaccine in the final stage (Phase III) of clinical trials (1). Therefore a model which excludes vaccination will most likely not be accurate to reality once a vaccine is widely administered.

      Source:

      1 https://www.who.int/publications/m/item/draft-landscape-of-covid-19-candidate-vaccines

  17. Sep 2020
  18. Aug 2020
    1. Sherrard-Smith, E., Hogan, A. B., Hamlet, A., Watson, O. J., Whittaker, C., Winskill, P., Ali, F., Mohammad, A. B., Uhomoibhi, P., Maikore, I., Ogbulafor, N., Nikau, J., Kont, M. D., Challenger, J. D., Verity, R., Lambert, B., Cairns, M., Rao, B., Baguelin, M., … Churcher, T. S. (2020). The potential public health consequences of COVID-19 on malaria in Africa. Nature Medicine, 1–6. https://doi.org/10.1038/s41591-020-1025-y

  19. Jul 2020
    1. O’Connor, D. B., Aggleton, J. P., Chakrabarti, B., Cooper, C. L., Creswell, C., Dunsmuir, S., Fiske, S. T., Gathercole, S., Gough, B., Ireland, J. L., Jones, M. V., Jowett, A., Kagan, C., Karanika‐Murray, M., Kaye, L. K., Kumari, V., Lewandowsky, S., Lightman, S., Malpass, D., … Armitage, C. J. (n.d.). Research priorities for the COVID-19 pandemic and beyond: A call to action for psychological science. British Journal of Psychology, n/a(n/a), e12468. https://doi.org/10.1111/bjop.12468

  20. Jun 2020
  21. May 2020
    1. Holmes, E. A., O’Connor, R. C., Perry, V. H., Tracey, I., Wessely, S., Arseneault, L., Ballard, C., Christensen, H., Silver, R. C., Everall, I., Ford, T., John, A., Kabir, T., King, K., Madan, I., Michie, S., Przybylski, A. K., Shafran, R., Sweeney, A., … Bullmore, E. (2020). Multidisciplinary research priorities for the COVID-19 pandemic: A call for action for mental health science. The Lancet Psychiatry, 0(0). https://doi.org/10.1016/S2215-0366(20)30168-1

  22. Apr 2020
    1. Because users read items from left to right, the priority direction for reading items is stronger horizontally than vertically.
    2. Items in a top navigation do not have equal weight. The leftmost items carry more visual weight than other items because of its placement in the primary optical area (top left). Items in the top left area get more exposure and are often seen as more important than other items.
    3. you will have certain items with higher priority than others. Because the user’s topic of interest is more limited in this context, placing items in a top navigation allows users to find what they want faster and easier.
  23. Nov 2019
  24. May 2019
    1. Vancouver-based Contextual Genomics has launched two molecular hotspot assays for detecting genomic mutations in blood and solid tumors. <!--//--><![CDATA[// ><!-- document.addEventListener("googletagEvent", function () { let hideOnMobile = "0"; let isMobileQuery = false; if (typeof window.dataLayerValues === "undefined" || !window.dataLayerValues.hasOwnProperty('isMobileQuery') || window.dataLayerValues.isMobileQuery) { isMobileQuery = window.dataLayerValues.isMobileQuery; } // Don't display the ad unit if this is a mobile browser and we're supposed to hide the unit in mobile view. if (isMobileQuery && hideOnMobile === '1') { return; } let hideOnDesktop = "0"; // Don't display this ad unit if this is a desktop broser and we're supposed to hide the mobile ad unit if(!isMobileQuery && hideOnDesktop === '1') { return; } googletag.cmd.push(function () { googletag.display('content-embed-one'); }); }); //--><!]]> The new version of the company’s Find It solid tumor panel now screens for 146 somatic genome alterations, and 23 exons in 30 cancer-associated genes, to help identify precision cancer treatments and recognize drug-resistant mutations. New additions to the panel include tests for mutations in the POLE gene, which have been associated with colorectal cancer as well as immunodeficiency.

      31-05-2019

  25. May 2017
    1. David Menasche’s Priority List

      I read this book for a class and highly enjoyed the priority lesson Menasche included in the overall theme of the book.

  26. Jul 2016
    1. Page 223

      This is Borgman discussing the role of priority in the humanities

      cultural and historical events can be reinterpreted repeatedly. Prizes are based on the best interpretation rather than on the first claim to a finding.