78 Matching Annotations
  1. Aug 2025
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    Computing hematopoiesis plasticity in response to genetic mutations and environmental stimulations
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    biorxiv.org/lookup/doi/10.1101/2024.08.02.606315
  3. Jul 2025
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    Multiple domains of scaffold Tudor protein play non-redundant roles in Drosophila germline
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    biorxiv.org/lookup/doi/10.1101/2025.03.13.643173
  5. May 2025
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    Canonical and non-canonical PRC1 differentially contribute to the regulation of neural stem cell fate
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    biorxiv.org/content/10.1101/2024.08.07.606990v1
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    FAM172A controls the nuclear import and alternative splicing function of AGO2
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    biorxiv.org/content/10.1101/2022.03.04.482948v2
  8. Nov 2024
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    Deregulation of multiple mechanisms shapes the onset of LAMA2-congenital muscular dystrophy
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    biorxiv.org/content/10.1101/2024.01.20.576409v1
  10. Jun 2024
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    Trim66 paternal deficiency causes intrauterine overgrowth
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    biorxiv.org/content/10.1101/2024.02.12.579976v1
  12. Feb 2024
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    Histology-associated transcriptomic heterogeneity in ovarian folliculogenesis revealed by quantitative single-cell RNA-sequencing for tissue sections with DRaqL
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    biorxiv.org/content/10.1101/2022.12.14.520513v1
  14. Jan 2024
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    Convergent Insulin and TGF-β signalling drives cancer cachexia by promoting aberrant fatbody ECM accumulation in a Drosophila tumour model
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    biorxiv.org/content/10.1101/2023.06.10.544444v1
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    Changes in searching behaviour of CSL transcription complexes in Notch active conditions
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    biorxiv.org/content/10.1101/2023.08.10.552734v2
  17. docdrop.org docdrop.org
    Video: Michael Levin: What Is The Field Of Diverse Intelligence? (DocDrop)
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    docdrop.org/video/kMxTS7eKkNM/
  18. docdrop.org docdrop.org
    Video: Can cells think? | Michael Levin (DocDrop)
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    docdrop.org/video/0a3xg4M9Oa8/
  19. Dec 2023
  20. www.biorxiv.org www.biorxiv.org
    Protein phosphatase 1 regulates core PCP signaling
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    biorxiv.org/content/10.1101/2023.09.12.556998v1
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    Automated staging of zebrafish embryos with deep learning
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    biorxiv.org/content/10.1101/2023.01.13.523922v2
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    MICA: A multi-omics method to predict gene regulatory networks in early human embryos
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    biorxiv.org/content/10.1101/2023.02.03.527081v2
  23. Nov 2023
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    Comprehensive comparison of female germ cell development in vitro and in vivo identifies epigenetic gene regulation crucial for oocyte development and embryonic competence
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    biorxiv.org/content/10.1101/2023.02.15.528760v1
  25. Oct 2023
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    EMBRYO-UTERINE INTERACTION COORDINATES MOUSE EMBRYOGENESIS DURING IMPLANTATION
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    biorxiv.org/content/10.1101/2022.06.13.495767v1
  27. Sep 2023
  28. docdrop.org docdrop.org
    Video: The beauty of collective intelligence, explained by a developmental biologist | Michael Levin (DocDrop)
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    1. stopresetgo 10 Sep 2023

      • for: Michael Levine, developmental biology, human superorganism, multi-scale competency architecture, eukaryote multi-cellular superorganism - interlevel communication, interoception

      • definition: multi-scale competency architecture

        • a complex living organism is not simply nested structurally in terms of cells which comprise tissues, comprising organs, and bodies, and then ultimately societies. Each of these layers has certain problem-solving competencies.

      • comment

        • The HUMAN interBEcomING is a multi-level system.
        • It would be insightful to learn if there are ways our human consciousness level can communicate to each level, including the social level
      • future work
        • literature review of research on specific areas related to the level of human consciousness communicating with other levels of the superorganism
          • perhaps called "interlevel communication of multi-level superorganism
          • interoception signals?
      human superorganism superorganism multi-scale competency architeccture Michael Levin developmental biology social superorganism eukaryote multicellular superorganism - interlevel communication interoception
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    docdrop.org/video/U93x9AWeuOA/
  29. www.biorxiv.org www.biorxiv.org
    Origin and segregation of the human germline
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    biorxiv.org/content/10.1101/2022.07.06.498671v1
  30. Aug 2023
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    Randomly incorporated genomic 6mA delays zygotic transcription initiation
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    biorxiv.org/content/10.1101/2022.10.27.514014v1
  32. Jun 2023
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    Deterministic and probabilistic fate decisions co-exist in a single retinal lineage
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    biorxiv.org/content/10.1101/2022.08.11.503564v1
  34. May 2023
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    VEGFR3 modulates brain microvessel branching in a mouse model of 22q11.2 deletion syndrome
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    biorxiv.org/content/10.1101/2022.03.16.484566v1
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    Functional substitutions of amino acids that differ between GDF11 and GDF8 impact skeletal development and skeletal muscle.
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    biorxiv.org/content/10.1101/2022.05.09.491247v1
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    Caspase-dependent activation of Hedgehog-signalling sustains proliferation and differentiation of ovarian somatic stem cells.
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    biorxiv.org/content/10.1101/722330v3
  38. Apr 2023
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    Single cell analysis of lymphatic endothelial cell fate specification and differentiation during zebrafish development
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    biorxiv.org/content/10.1101/2022.02.10.479999v2
  40. Mar 2023
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    Stepwise progression of beta-selection during T cell development as revealed by histone deacetylation inhibition
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    biorxiv.org/content/10.1101/2021.10.03.462949v4
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    E-Cadherin mediated AMIS localisation
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    biorxiv.org/content/10.1101/2021.11.30.470571v5
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    The Grainyhead/LSF transcription factor GRH-1 is rhythmically required for molting
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    biorxiv.org/content/10.1101/2022.03.01.482504v2
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    Production of offspring from azoospermic mice with meiotic failure: Precise biparental meiosis within halved oocytes
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    biorxiv.org/content/10.1101/2021.09.03.458818v4
  45. Feb 2023
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    The blood vasculature instructs lymphatics patterning in a SOX7-dependent manner
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    biorxiv.org/content/10.1101/2021.07.02.450967v1
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    NuRD independent Mi-2 activity represses ectopic gene expression during neuronal maturation.
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    biorxiv.org/content/10.1101/2022.04.19.488642v3
  48. Jan 2023
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    Identifying novel regulators of placental development using time series transcriptomic data and network analyses
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    biorxiv.org/content/10.1101/2022.05.17.492330v1
  50. Dec 2022
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    Cdh5-lineage independent origin of dermal lymphatic vessels revealed by temporally restricted lineage tracing
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    biorxiv.org/content/10.1101/2022.06.08.495310v1
  52. Nov 2022
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    The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging
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    biorxiv.org/content/10.1101/2022.02.28.482241v1
  54. www.biorxiv.org www.biorxiv.org
    m6A is required for resolving progenitor identity during planarian stem cell differentiation
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    biorxiv.org/content/10.1101/2021.07.27.453979v1
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    Bleeding in patients and mice with Alagille syndrome: sex differences and risk factors
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    biorxiv.org/content/10.1101/2021.04.13.439679v2
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    Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc
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    biorxiv.org/content/10.1101/2021.09.11.459911v1
  57. www.biorxiv.org www.biorxiv.org
    A temporally controlled sequence of X-chromosomeinactivation and reactivation defines female mouse in vitro germ cells with meiotic potential
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    biorxiv.org/content/10.1101/2021.08.11.455976v3
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    TRiC activates the unfolded protein response and protects starved stem cells by modulating energy and lipid metabolism during planarian regeneration
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    biorxiv.org/content/10.1101/732875v1
  59. Mar 2022
  60. www.biorxiv.org www.biorxiv.org
    The expression of essential selenoproteins during zebrafish development requires SECIS binding protein 2-like
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    biorxiv.org/content/10.1101/2021.11.01.466845v1
  61. www.biorxiv.org www.biorxiv.org
    A Cdc42-Borg4-Septin 7 axis regulates HSCs polarity and function
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    biorxiv.org/content/10.1101/2021.03.17.435817v1
  62. Jan 2022
  63. www.biorxiv.org www.biorxiv.org
    Rbfox1 is required for myofibril development and maintaining fiber-type specific isoform expression in Drosophila muscles
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    biorxiv.org/content/10.1101/2021.05.09.443278v1
  64. www.biorxiv.org www.biorxiv.org
    An exon junction complex-independent function of Barentsz in neuromuscular synapse growth
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    biorxiv.org/content/10.1101/2021.02.13.430688v1
  65. Dec 2021
  66. www.biorxiv.org www.biorxiv.org
    Traction forces exerted by the developing optic cup mediate cell movements and axon extension in the olfactory placode
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    biorxiv.org/content/10.1101/2021.03.15.435408v2
  67. Nov 2021
  68. www.biorxiv.org www.biorxiv.org
    Delta C2 Domain β1-2 loop contributes to robust Notch signalling
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    biorxiv.org/lookup/doi/10.1101/2021.02.16.431397
  69. Oct 2021
  70. www.biorxiv.org www.biorxiv.org
    Resf1 deletion reduces the efficiency of embryonic stem cell self-renewal and germline entry
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    biorxiv.org/content/10.1101/2021.05.25.445589v2
  71. www.biorxiv.org www.biorxiv.org
    Foxm1 regulates neuronal progenitor fate during spinal cord regeneration
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    biorxiv.org/content/10.1101/2020.02.26.962977v1
  72. Sep 2021
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    Msps Governs Acentrosomal Microtubule Assembly and Reactivation of Quiescent Neural Stem Cells
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    biorxiv.org/content/10.1101/2020.01.24.918227v1
  74. Jul 2021
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    Edem1 activity in the fat body regulates insulin signalling and metabolic homeostasis in Drosophila
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    biorxiv.org/lookup/doi/10.1101/671305
  76. www.biorxiv.org www.biorxiv.org
    Characterization of histone inheritance patterns in the Drosophila female germline
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    biorxiv.org/content/10.1101/2020.08.18.255455v1
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    A dynamic and spatially periodic micro-pattern of HES5 expression underlies the probability of neuronal differentiation in the mouse spinal cord
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    biorxiv.org/content/10.1101/2020.08.03.234369v2
  78. Jun 2021
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    CyclinD1 controls development of cerebellar granule cell progenitors through phosphorylation and stabilization of ATOH1
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    biorxiv.org/content/10.1101/2020.03.27.010926v1
  80. May 2021
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    Somatic transposition in the Drosophila intestine occurs in active chromatin and is associated with tumor suppressor gene inactivation
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    biorxiv.org/content/10.1101/2020.07.10.166629v1
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    REPRESSION BY HDAC3 AND DAX1 MEDIATES LINEAGE RESTRICTION OF EMBRYONIC STEM CELLS
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    biorxiv.org/content/10.1101/2020.09.10.291013v1
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    Multidimensional Chromatin Regulation of Cell Lineage Differentiation in a Metazoan Embryo
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    biorxiv.org/content/10.1101/2020.05.18.101584v1
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    Combinatorial action of transcription factors in open chromatin contributes to early cellular heterogeneity and organizer mesendoderm specification.
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    biorxiv.org/content/10.1101/2020.02.26.966168v1
  85. Apr 2021
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    Glial Hedgehog and lipid metabolism regulate neural stem cell proliferation in Drosophila
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    biorxiv.org/content/10.1101/2020.05.18.100990v2
  87. www.biorxiv.org www.biorxiv.org
    Membrane potential regulates Hedgehog signaling and compartment boundary maintenance in the Drosophila wing disc
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    biorxiv.org/content/10.1101/2020.06.02.128892v1
  88. Feb 2021
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    Gradual centriole maturation associates with the mitotic surveillance pathway in mouse development
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    biorxiv.org/content/10.1101/2020.07.24.219402v1
  90. www.biorxiv.org www.biorxiv.org
    Modulation of Yorkie activity by alternative splicing is required for developmental stability
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    biorxiv.org/content/10.1101/2019.12.19.882779v1
  91. www.biorxiv.org www.biorxiv.org
    Non-apoptotic caspase-dependent regulation of enteroblast quiescence in Drosophila
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    biorxiv.org/content/10.1101/707380v1
  92. Oct 2020
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    Stage-specific transcriptomes and DNA methylomes indicate an early and transient loss of transposon control in Arabidopsis shoot stem cells
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    biorxiv.org/content/10.1101/430447v2
  94. Jul 2020
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    Temporal specificity and heterogeneity of the fly immune cells' transcriptional landscape
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    biorxiv.org/content/10.1101/2019.12.20.871301v1
  96. www.biorxiv.org www.biorxiv.org
    miR-9 mediated noise optimization of the her6 oscillator is needed for cell state progression in the Zebrafish hindbrain
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    biorxiv.org/content/10.1101/608604v1
  97. www.biorxiv.org www.biorxiv.org
    MTA proteins act redundantly within the NuRD complex to ensure fidelity of ES cell lineage commitment
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    biorxiv.org/content/10.1101/362988v2
  98. Jun 2020
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    BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression
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    biorxiv.org/content/10.1101/2019.12.13.876268v2
  100. Nov 2019
  101. www.biorxiv.org www.biorxiv.org
    Endogenous fluctuations of OCT4 and SOX2 bias pluripotent cell fate decisions
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    biorxiv.org/content/10.1101/299073v3
  102. Sep 2019
  103. www.biorxiv.org www.biorxiv.org
    let-7 controls the transition to adulthood by releasing select transcriptional regulators from repression by LIN41
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    biorxiv.org/content/10.1101/460352v1
  104. www.biorxiv.org www.biorxiv.org
    Maternal Circulating MicroRNAs Control the Placental Response to Alcohol
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    biorxiv.org/content/10.1101/409854v3
  105. www.biorxiv.org www.biorxiv.org
    A genetic system for generating single-sex progeny in mice
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    biorxiv.org/content/10.1101/515064v2
  106. www.biorxiv.org www.biorxiv.org
    SWI/SNF chromatin remodeling controls Notch-responsive enhancer accessibility
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    biorxiv.org/content/10.1101/399501v1
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    Bimodal Spindle Orientation Drives Tissue Regularity in a Proliferating Epithelium
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    biorxiv.org/content/10.1101/178517v3
  108. www.biorxiv.org www.biorxiv.org
    A common molecular logic determines embryonic stem cell self-renewal and reprogramming
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    biorxiv.org/content/10.1101/200501v2
  109. www.biorxiv.org www.biorxiv.org
    Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth
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    biorxiv.org/content/10.1101/300053v1
  110. www.biorxiv.org www.biorxiv.org
    Bicoid gradient formation mechanism and dynamics revealed by protein lifetime analysis
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    biorxiv.org/content/10.1101/280834v1
  111. www.biorxiv.org www.biorxiv.org
    The Trithorax group protein dMLL3/4 instructs the assembly of the zygotic genome at fertilization
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    biorxiv.org/content/10.1101/242008v1
  112. www.biorxiv.org www.biorxiv.org
    WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome
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    biorxiv.org/content/10.1101/200154v1
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    Aubergine And piRNAs Repress The Proto-Oncogene Cbl For Germline Stem Cell Self-Renewal
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    biorxiv.org/content/10.1101/134304v1
  114. www.biorxiv.org www.biorxiv.org
    Polarized Cortical Tension drives Zebrafish Epiboly Movements
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    biorxiv.org/content/10.1101/032284v1