15 Matching Annotations
  1. Nov 2019
    1. tools described here can be used to mimic complex expression patterns, such as the ones found for pneumococcal virulence factors, paving the way for in vivo investigations of the importance of gene expression control on the pathogenicity of S. pneumoniae.
    2. It is challenging to study how pneumococci control virulence factor expression, because cues of natural environments and the presence of an immune system are difficult to simulate in vitro
  2. Oct 2019
    1. includes creation of innovative solutions for bio energy, resource recovery, and emerging public health concerns by leveraging synthetic or molecular biology tools, novel biological systems (genetic circuits, enzymes, genetically engineered microbes), fundamental biological and chemical concepts, artificial intelligence, and big data science, as well as collaborations in Computer Science, Public Health, Plant Biology, or related fields.
  3. Sep 2019
    1. MicroBio Engineering Inc., a research and engineering consulting firm specializing in developing improved algal strains and cultivation processes for wastewater reclamation, animal feeds, higher value products and, yes, biofuels.
    1. In Japan, scientists are developing synthetically altered soy plants and yeast that produce glycyrrhizen, a compound in licorice root that is 150 to 300 times sweeter than sugar
  4. Apr 2017
    1. approaches have proven invaluable for understanding metabo-lism and improving metabolite production (Wiechert 2002;Patilet al. 2004), metabolic engineering ‘design principles’ are yet tobe fully elucidated due to our incomplete knowledge of livingsystems. Subsequently, it can take many iterations of the classi-cal design-build-test cycle to achieve engineering objectives,some of which may even be impossible to meet using availablebiological knowledge.An elegant way to overcome the challenges associated withengineering in biology is to apply a selective pressure to a genet-ically diverse population so that cells with the desired pheno-type can be isolated.

      This is key!